SARS-CoV-2 infection produces chronic pulmonary epithelial and immune cell dysfunction with fibrosis in mice

por Dinnon, Kenneth H., Leist, Sarah R., Okuda, Kenichi, Dang, Hong, Fritch, Ethan J., Gully, Kendra L., De la Cruz, Gabriela, Evangelista, Mia D., Asakura, Takanori, Gilmore, Rodney C., Hawkins, Padraig, Nakano, Satoko, West, Ande, Schäfer, Alexandra, Gralinski, Lisa E., Everman, Jamie L., Sajuthi, Satria P., Zweigart, Mark R., Dong, Stephanie, McBride, Jennifer, Cooley, Michelle R., Hines, Jesse B., Love, Miriya K., Groshong, Steve D., VanSchoiack, Alison, Phelan, Stefan J., Liang, Yan, Hether, Tyler, Leon, Michael, Zumwalt, Ross E., Barton, Lisa M., Duval, Eric J., Mukhopadhyay, Sanjay, Stroberg, Edana, Borczuk, Alain, Thorne, Leigh B., Sakthivel, Muthu K., Lee, Yueh Z., Hagood, James S., Mock, Jason R., Seibold, Max A., O’Neal, Wanda K., Montgomery, Stephanie A., Boucher, Richard C., Baric, Ralph S.
Publicado 2022

Genome-wide bidirectional CRISPR screens identify mucins as host factors modulating SARS-CoV-2 infection

por Biering, Scott B., Sarnik, Sylvia A., Wang, Eleanor, Zengel, James R., Leist, Sarah R., Schäfer, Alexandra, Sathyan, Varun, Hawkins, Padraig, Okuda, Kenichi, Tau, Cyrus, Jangid, Aditya R., Duffy, Connor V., Wei, Jin, Gilmore, Rodney C., Alfajaro, Mia Madel, Strine, Madison S., Nguyenla, Xammy, Van Dis, Erik, Catamura, Carmelle, Yamashiro, Livia H., Belk, Julia A., Begeman, Adam, Stark, Jessica C., Shon, D. Judy, Fox, Douglas M., Ezzatpour, Shahrzad, Huang, Emily, Olegario, Nico, Rustagi, Arjun, Volmer, Allison S., Livraghi-Butrico, Alessandra, Wehri, Eddie, Behringer, Richard R., Cheon, Dong-Joo, Schaletzky, Julia, Aguilar, Hector C., Puschnik, Andreas S., Button, Brian, Pinsky, Benjamin A., Blish, Catherine A., Baric, Ralph S., O’Neal, Wanda K., Bertozzi, Carolyn R., Wilen, Craig B., Boucher, Richard C., Carette, Jan E., Stanley, Sarah A., Harris, Eva, Konermann, Silvana, Hsu, Patrick D.
Publicado 2022

The neutralizing antibody, LY-CoV555, protects against SARS-CoV-2 infection in nonhuman primates

por Jones, Bryan E., Brown-Augsburger, Patricia L., Corbett, Kizzmekia S., Westendorf, Kathryn, Davies, Julian, Cujec, Thomas P., Wiethoff, Christopher M., Blackbourne, Jamie L., Heinz, Beverly A., Foster, Denisa, Higgs, Richard E., Balasubramaniam, Deepa, Wang, Lingshu, Zhang, Yi, Yang, Eun Sung, Bidshahri, Roza, Kraft, Lucas, Hwang, Yuri, Žentelis, Stefanie, Jepson, Kevin R., Goya, Rodrigo, Smith, Maia A., Collins, David W., Hinshaw, Samuel J., Tycho, Sean A., Pellacani, Davide, Xiang, Ping, Muthuraman, Krithika, Sobhanifar, Solmaz, Piper, Marissa H., Triana, Franz J., Hendle, Jorg, Pustilnik, Anna, Adams, Andrew C., Berens, Shawn J., Baric, Ralph S., Martinez, David R., Cross, Robert W., Geisbert, Thomas W., Borisevich, Viktoriya, Abiona, Olubukola, Belli, Hayley M., de Vries, Maren, Mohamed, Adil, Dittmann, Meike, Samanovic, Marie I., Mulligan, Mark J., Goldsmith, Jory A., Hsieh, Ching-Lin, Johnson, Nicole V., Wrapp, Daniel, McLellan, Jason S., Barnhart, Bryan C., Graham, Barney S., Mascola, John R., Hansen, Carl L., Falconer, Ester
Publicado 2021

Ultrapotent antibodies against diverse and highly transmissible SARS-CoV-2 variants

por Wang, Lingshu, Zhou, Tongqing, Zhang, Yi, Yang, Eun Sung, Schramm, Chaim A., Shi, Wei, Pegu, Amarendra, Oloniniyi, Olamide K., Henry, Amy R., Darko, Samuel, Narpala, Sandeep R., Hatcher, Christian, Martinez, David R., Tsybovsky, Yaroslav, Phung, Emily, Abiona, Olubukola M., Antia, Avan, Cale, Evan M., Chang, Lauren A., Choe, Misook, Corbett, Kizzmekia S., Davis, Rachel L., DiPiazza, Anthony T., Gordon, Ingelise J., Hait, Sabrina Helmold, Hermanus, Tandile, Kgagudi, Prudence, Laboune, Farida, Leung, Kwanyee, Liu, Tracy, Mason, Rosemarie D., Nazzari, Alexandra F., Novik, Laura, O’Connell, Sarah, O’Dell, Sijy, Olia, Adam S., Schmidt, Stephen D., Stephens, Tyler, Stringham, Christopher D., Talana, Chloe Adrienna, Teng, I-Ting, Wagner, Danielle A., Widge, Alicia T., Zhang, Baoshan, Roederer, Mario, Ledgerwood, Julie E., Ruckwardt, Tracy J., Gaudinski, Martin R., Moore, Penny L., Doria-Rose, Nicole A., Baric, Ralph S., Graham, Barney S., McDermott, Adrian B., Douek, Daniel C., Kwong, Peter D., Mascola, John R., Sullivan, Nancy J., Misasi, John
Publicado 2021

SARS-CoV-2 mRNA Vaccine Design Enabled by Prototype Pathogen Preparedness

por Corbett, Kizzmekia S., Edwards, Darin K., Leist, Sarah R., Abiona, Olubukola M., Boyoglu-Barnum, Seyhan, Gillespie, Rebecca A., Himansu, Sunny, Schäfer, Alexandra, Ziwawo, Cynthia T., DiPiazza, Anthony T., Dinnon, Kenneth H., Elbashir, Sayda M., Shaw, Christine A., Woods, Angela, Fritch, Ethan J., Martinez, David R., Bock, Kevin W., Minai, Mahnaz, Nagata, Bianca M., Hutchinson, Geoffrey B., Wu, Kai, Henry, Carole, Bahi, Kapil, Garcia-Dominguez, Dario, Ma, LingZhi, Renzi, Isabella, Kong, Wing-Pui, Schmidt, Stephen D., Wang, Lingshu, Zhang, Yi, Phung, Emily, Chang, Lauren A., Loomis, Rebecca J., Altaras, Nedim Emil, Narayanan, Elisabeth, Metkar, Mihir, Presnyak, Vlad, Liu, Cuiping, Louder, Mark K., Shi, Wei, Leung, Kwanyee, Yang, Eun Sung, West, Ande, Gully, Kendra L., Stevens, Laura J., Wang, Nianshuang, Wrapp, Daniel, Doria-Rose, Nicole A., Stewart-Jones, Guillaume, Bennett, Hamilton, Alvarado, Gabriela S., Nason, Martha C., Ruckwardt, Tracy J., McLellan, Jason S., Denison, Mark R., Chappell, James D., Moore, Ian N., Morabito, Kaitlyn M., Mascola, John R., Baric, Ralph S., Carfi, Andrea, Graham, Barney S.
Publicado 2020

Single-Shot Ad26 Vaccine Protects Against SARS-CoV-2 in Rhesus Macaques

por Mercado, Noe B., Zahn, Roland, Wegmann, Frank, Loos, Carolin, Chandrashekar, Abishek, Yu, Jingyou, Liu, Jinyan, Peter, Lauren, McMahan, Katherine, Tostanoski, Lisa H., He, Xuan, Martinez, David R., Rutten, Lucy, Bos, Rinke, van Manen, Danielle, Vellinga, Jort, Custers, Jerome, Langedijk, Johannes P., Kwaks, Ted, Bakkers, Mark J.G., Zuijdgeest, David, Huber, Sietske K. Rosendahl, Atyeo, Caroline, Fischinger, Stephanie, Burke, John S., Feldman, Jared, Hauser, Blake M., Caradonna, Timothy M., Bondzie, Esther A., Dagotto, Gabriel, Gebre, Makda S., Hoffman, Emily, Jacob-Dolan, Catherine, Kirilova, Marinela, Li, Zhenfeng, Lin, Zijin, Mahrokhian, Shant H., Maxfield, Lori F., Nampanya, Felix, Nityanandam, Ramya, Nkolola, Joseph P., Patel, Shivani, Ventura, John D., Verrington, Kaylee, Wan, Huahua, Pessaint, Laurent, Van Ry, Alex, Blade, Kelvin, Strasbaugh, Amanda, Cabus, Mehtap, Brown, Renita, Cook, Anthony, Zouantchangadou, Serge, Teow, Elyse, Andersen, Hanne, Lewis, Mark G., Cai, Yongfei, Chen, Bing, Schmidt, Aaron G., Reeves, R. Keith, Baric, Ralph S., Lauffenburger, Douglas A., Alter, Galit, Stoffels, Paul, Mammen, Mathai, Van Hoof, Johan, Schuitemaker, Hanneke, Barouch, Dan H.
Publicado 2020

In vitro and in vivo functions of SARS-CoV-2 infection-enhancing and neutralizing antibodies

por Li, Dapeng, Edwards, Robert J., Manne, Kartik, Martinez, David R., Schäfer, Alexandra, Alam, S. Munir, Wiehe, Kevin, Lu, Xiaozhi, Parks, Robert, Sutherland, Laura L., Oguin, Thomas H., McDanal, Charlene, Perez, Lautaro G., Mansouri, Katayoun, Gobeil, Sophie M.C., Janowska, Katarzyna, Stalls, Victoria, Kopp, Megan, Cai, Fangping, Lee, Esther, Foulger, Andrew, Hernandez, Giovanna E., Sanzone, Aja, Tilahun, Kedamawit, Jiang, Chuancang, Tse, Longping V., Bock, Kevin W., Minai, Mahnaz, Nagata, Bianca M., Cronin, Kenneth, Gee-Lai, Victoria, Deyton, Margaret, Barr, Maggie, Von Holle, Tarra, Macintyre, Andrew N., Stover, Erica, Feldman, Jared, Hauser, Blake M., Caradonna, Timothy M., Scobey, Trevor D., Rountree, Wes, Wang, Yunfei, Moody, M. Anthony, Cain, Derek W., DeMarco, C. Todd, Denny, Thomas N., Woods, Christopher W., Petzold, Elizabeth W., Schmidt, Aaron G., Teng, I-Ting, Zhou, Tongqing, Kwong, Peter D., Mascola, John R., Graham, Barney S., Moore, Ian N., Seder, Robert, Andersen, Hanne, Lewis, Mark G., Montefiori, David C., Sempowski, Gregory D., Baric, Ralph S., Acharya, Priyamvada, Haynes, Barton F., Saunders, Kevin O.
Publicado 2021

A comprehensive collection of systems biology data characterizing the host response to viral infection

por Aevermann, Brian D., Pickett, Brett E., Kumar, Sanjeev, Klem, Edward B., Agnihothram, Sudhakar, Askovich, Peter S., Bankhead, Armand, Bolles, Meagen, Carter, Victoria, Chang, Jean, Clauss, Therese R.W., Dash, Pradyot, Diercks, Alan H., Eisfeld, Amie J., Ellis, Amy, Fan, Shufang, Ferris, Martin T., Gralinski, Lisa E., Green, Richard R., Gritsenko, Marina A., Hatta, Masato, Heegel, Robert A., Jacobs, Jon M., Jeng, Sophia, Josset, Laurence, Kaiser, Shari M., Kelly, Sara, Law, G. Lynn, Li, Chengjun, Li, Jiangning, Long, Casey, Luna, Maria L., Matzke, Melissa, McDermott, Jason, Menachery, Vineet, Metz, Thomas O., Mitchell, Hugh, Monroe, Matthew E., Navarro, Garnet, Neumann, Gabriele, Podyminogin, Rebecca L., Purvine, Samuel O., Rosenberger, Carrie M., Sanders, Catherine J., Schepmoes, Athena A., Shukla, Anil K., Sims, Amy, Sova, Pavel, Tam, Vincent C., Tchitchek, Nicolas, Thomas, Paul G., Tilton, Susan C., Totura, Allison, Wang, Jing, Webb-Robertson, Bobbie-Jo, Wen, Ji, Weiss, Jeffrey M., Yang, Feng, Yount, Boyd, Zhang, Qibin, McWeeney, Shannon, Smith, Richard D., Waters, Katrina M., Kawaoka, Yoshihiro, Baric, Ralph, Aderem, Alan, Katze, Michael G., Scheuermann, Richard H.
Publicado 2014

Content and Performance of the MiniMUGA Genotyping Array: A New Tool To Improve Rigor and Reproducibility in Mouse Research

por Sigmon, John Sebastian, Blanchard, Matthew W., Baric, Ralph S., Bell, Timothy A., Brennan, Jennifer, Brockmann, Gudrun A., Burks, A. Wesley, Calabrese, J. Mauro, Caron, Kathleen M., Cheney, Richard E., Ciavatta, Dominic, Conlon, Frank, Darr, David B., Faber, James, Franklin, Craig, Gershon, Timothy R., Gralinski, Lisa, Gu, Bin, Gaines, Christiann H., Hagan, Robert S., Heimsath, Ernest G., Heise, Mark T., Hock, Pablo, Ideraabdullah, Folami, Jennette, J. Charles, Kafri, Tal, Kashfeen, Anwica, Kulis, Mike, Kumar, Vivek, Linnertz, Colton, Livraghi-Butrico, Alessandra, Lloyd, K. C. Kent, Lutz, Cathleen, Lynch, Rachel M., Magnuson, Terry, Matsushima, Glenn K., McMullan, Rachel, Miller, Darla R., Mohlke, Karen L., Moy, Sheryl S., Murphy, Caroline E. Y., Najarian, Maya, O’Brien, Lori, Palmer, Abraham A., Philpot, Benjamin D., Randell, Scott H., Reinholdt, Laura, Ren, Yuyu, Rockwood, Steve, Rogala, Allison R., Saraswatula, Avani, Sassetti, Christopher M., Schisler, Jonathan C., Schoenrock, Sarah A., Shaw, Ginger D., Shorter, John R., Smith, Clare M., St. Pierre, Celine L., Tarantino, Lisa M., Threadgill, David W., Valdar, William, Vilen, Barbara J., Wardwell, Keegan, Whitmire, Jason K., Williams, Lucy, Zylka, Mark J., Ferris, Martin T., McMillan, Leonard, Manuel de Villena, Fernando Pardo
Publicado 2020

Evaluation of the mRNA-1273 Vaccine against SARS-CoV-2 in Nonhuman Primates

por Corbett, Kizzmekia S., Flynn, Barbara, Foulds, Kathryn E., Francica, Joseph R., Boyoglu-Barnum, Seyhan, Werner, Anne P., Flach, Britta, O’Connell, Sarah, Bock, Kevin W., Minai, Mahnaz, Nagata, Bianca M., Andersen, Hanne, Martinez, David R., Noe, Amy T., Douek, Naomi, Donaldson, Mitzi M., Nji, Nadesh N., Alvarado, Gabriela S., Edwards, Darin K., Flebbe, Dillon R., Lamb, Evan, Doria-Rose, Nicole A., Lin, Bob C., Louder, Mark K., O’Dell, Sijy, Schmidt, Stephen D., Phung, Emily, Chang, Lauren A., Yap, Christina, Todd, John-Paul M., Pessaint, Laurent, Van Ry, Alex, Browne, Shanai, Greenhouse, Jack, Putman-Taylor, Tammy, Strasbaugh, Amanda, Campbell, Tracey-Ann, Cook, Anthony, Dodson, Alan, Steingrebe, Katelyn, Shi, Wei, Zhang, Yi, Abiona, Olubukola M., Wang, Lingshu, Pegu, Amarendra, Yang, Eun Sung, Leung, Kwanyee, Zhou, Tongqing, Teng, I-Ting, Widge, Alicia, Gordon, Ingelise, Novik, Laura, Gillespie, Rebecca A., Loomis, Rebecca J., Moliva, Juan I., Stewart-Jones, Guillaume, Himansu, Sunny, Kong, Wing-Pui, Nason, Martha C., Morabito, Kaitlyn M., Ruckwardt, Tracy J., Ledgerwood, Julie E., Gaudinski, Martin R., Kwong, Peter D., Mascola, John R., Carfi, Andrea, Lewis, Mark G., Baric, Ralph S., McDermott, Adrian, Moore, Ian N., Sullivan, Nancy J., Roederer, Mario, Seder, Robert A., Graham, Barney S.
Publicado 2020

Mission, Organization, and Future Direction of the Serological Sciences Network for COVID-19 (SeroNet) Epidemiologic Cohort Studies

por Figueiredo, Jane C, Hirsch, Fred R, Kushi, Lawrence H, Nembhard, Wendy N, Crawford, James M, Mantis, Nicholas, Finster, Laurel, Merin, Noah M, Merchant, Akil, Reckamp, Karen L, Melmed, Gil Y, Braun, Jonathan, McGovern, Dermot, Parekh, Samir, Corley, Douglas A, Zohoori, Namvar, Amick, Benjamin C, Du, Ruofei, Gregersen, Peter K, Diamond, Betty, Taioli, Emanuela, Sariol, Carlos, Espino, Ana, Weiskopf, Daniela, Gifoni, Alba, Brien, James, Hanege, William, Lipsitch, Marc, Zidar, David A, Scheck McAlearney, Ann, Wajnberg, Ania, LaBaer, Joshua, Yvonne Lewis, E, Binder, Raquel A, Moormann, Ann M, Forconi, Catherine, Forrester, Sarah, Batista, Jennifer, Schieffelin, John, Kim, Dongjoo, Biancon, Giulia, VanOudenhove, Jennifer, Halene, Stephanie, Fan, Rong, Barouch, Dan H, Alter, Galit, Pinninti, Swetha, Boppana, Suresh B, Pati, Sunil K, Latting, Misty, Karaba, Andrew H, Roback, John, Sekaly, Rafick, Neish, Andrew, Brincks, Ahnalee M, Granger, Douglas A, Karger, Amy B, Thyagarajan, Bharat, Thomas, Stefani N, Klein, Sabra L, Cox, Andrea L, Lucas, Todd, Furr-Holden, Debra, Key, Kent, Jones, Nicole, Wrammerr, Jens, Suthar, Mehul, Yu Wong, Serre, Bowman, Natalie M, Simon, Viviana, Richardson, Lynne D, McBride, Russell, Krammer, Florian, Rana, Meenakshi, Kennedy, Joshua, Boehme, Karl, Forrest, Craig, Granger, Steve W, Heaney, Christopher D, Knight Lapinski, Maria, Wallet, Shannon, Baric, Ralph S, Schifanella, Luca, Lopez, Marcos, Fernández, Soledad, Kenah, Eben, Panchal, Ashish R, Britt, William J, Sanz, Iñaki, Dhodapkar, Madhav, Ahmed, Rafi, Bartelt, Luther A, Markmann, Alena J, Lin, Jessica T, Hagan, Robert S, Wolfgang, Matthew C, Skarbinski, Jacek
Publicado 2022

Durability of mRNA-1273 vaccine–induced antibodies against SARS-CoV-2 variants

por Pegu, Amarendra, O’Connell, Sarah E., Schmidt, Stephen D., O’Dell, Sijy, Talana, Chloe A., Lai, Lilin, Albert, Jim, Anderson, Evan, Bennett, Hamilton, Corbett, Kizzmekia S., Flach, Britta, Jackson, Lisa, Leav, Brett, Ledgerwood, Julie E., Luke, Catherine J., Makowski, Mat, Nason, Martha C., Roberts, Paul C., Roederer, Mario, Rebolledo, Paulina A., Rostad, Christina A., Rouphael, Nadine G., Shi, Wei, Wang, Lingshu, Widge, Alicia T., Yang, Eun Sung, Beigel, John H., Graham, Barney S., Mascola, John R., Suthar, Mehul S., McDermott, Adrian B., Doria-Rose, Nicole A., Arega, Jae, Beigel, John H., Buchanan, Wendy, Elsafy, Mohammed, Hoang, Binh, Lampley, Rebecca, Kolhekar, Aparna, Koo, Hyung, Luke, Catherine, Makhene, Mamodikoe, Nayak, Seema, Pikaart-Tautges, Rhonda, Roberts, Paul C., Russell, Janie, Sindall, Elisa, Albert, Jim, Kunwar, Pratap, Makowski, Mat, Anderson, Evan J., Bechnak, Amer, Bower, Mary, Camacho-Gonzalez, Andres F., Collins, Matthew, Drobeniuc, Ana, Edara, Venkata Viswanadh, Edupuganti, Srilatha, Floyd, Katharine, Gibson, Theda, Ackerley, Cassie M. Grimsley, Johnson, Brandi, Kamidani, Satoshi, Kao, Carol, Kelley, Colleen, Lai, Lilin, Macenczak, Hollie, McCullough, Michele Paine, Peters, Etza, Phadke, Varun K., Rebolledo, Paulina A., Rostad, Christina A., Rouphael, Nadine, Scherer, Erin, Sherman, Amy, Stephens, Kathy, Suthar, Mehul S., Teherani, Mehgan, Traenkner, Jessica, Winston, Juton, Yildirim, Inci, Barr, Lee, Benoit, Joyce, Carste, Barbara, Choe, Joe, Dunstan, Maya, Erolin, Roxanne, ffitch, Jana, Fields, Colin, Jackson, Lisa A., Kiniry, Erika, Lasicka, Susan, Lee, Stella, Nguyen, Matthew, Pimienta, Stephanie, Suyehira, Janice, Witte, Michael, Bennett, Hamilton, Altaras, Nedim Emil, Carfi, Andrea, Hurley, Marjorie, Leav, Brett, Pajon, Rolando, Sun, Wellington, Zaks, Tal, Coler, Rhea N., Larsen, Sasha E., Neuzil, Kathleen M., Lindesmith, Lisa C., Martinez, David R., Munt, Jennifer, Mallory, Michael, Edwards, Caitlin, Baric, Ralph S., Berkowitz, Nina M., Boritz, Eli A., Carlton, Kevin, Corbett, Kizzmekia S., Costner, Pamela, Creanga, Adrian, Doria-Rose, Nicole A., Douek, Daniel C., Flach, Britta, Gaudinski, Martin, Gordon, Ingelise, Graham, Barney S., Holman, LaSonji, Ledgerwood, Julie E., Leung, Kwanyee, Lin, Bob C., Louder, Mark K., Mascola, John R., McDermott, Adrian B., Morabito, Kaitlyn M., Novik, Laura, O’Connell, Sarah, O’Dell, Sijy, Padilla, Marcelino, Pegu, Amarendra, Schmidt, Stephen D., Shi, Wei, Swanson, Phillip A., Talana, Chloe A., Wang, Lingshu, Widge, Alicia T., Yang, Eun Sung, Zhang, Yi, Chappell, James D., Denison, Mark R., Hughes, Tia, Lu, Xiaotao, Pruijssers, Andrea J., Stevens, Laura J., Posavad, Christine M., Gale, Michael, Menachery, Vineet, Shi, Pei-Yong
Publicado 2021