The Immunomodulatory Role of Adjuvants in Vaccines Formulated with the Recombinant Antigens Ov-103 and Ov-RAL-2 against Onchocerca volvulus in Mice

por Hess, Jessica A., Zhan, Bin, Torigian, April R., Patton, John B., Petrovsky, Nikolai, Zhan, Tingting, Bottazzi, Maria Elena, Hotez, Peter J., Klei, Thomas R., Lustigman, Sara, Abraham, David
Publicado 2016

Ligand binding properties of two Brugia malayi fatty acid and retinol (FAR) binding proteins and their vaccine efficacies against challenge infection in gerbils

por Zhan, Bin, Arumugam, Sridhar, Kennedy, Malcolm W., Tricoche, Nancy, Lian, Lu-Yun, Asojo, Oluwatoyin A., Bennuru, Sasisekhar, Bottazzi, Maria Elena, Hotez, Peter J., Lustigman, Sara, Klei, Thomas R.
Publicado 2018

Localized cardiac metabolic trajectories and post-infectious metabolic sequelae in experimental Chagas disease

por Liu, Zongyuan, Ulrich, Rebecca, Kendricks, April L., Wheeler, Kate, Leão, Ana Carolina, Pollet, Jeroen, Bottazzi, Maria Elena, Hotez, Peter, Gusovsky, Fabian, Jones, Kathryn M., McCall, Laura-Isobel
Publicado 2023

Process development and scale-up optimization of the SARS-CoV-2 receptor binding domain–based vaccine candidate, RBD219-N1C1

por Lee, Jungsoon, Liu, Zhuyun, Chen, Wen-Hsiang, Wei, Junfei, Kundu, Rakhi, Adhikari, Rakesh, Rivera, Joanne Altieri, Gillespie, Portia M., Strych, Ulrich, Zhan, Bin, Hotez, Peter J., Bottazzi, Maria Elena
Publicado 2021

Expression, purification, and characterization of the Necator americanus aspartic protease-1 (Na-APR-1 (M74)) antigen, a component of the bivalent human hookworm vaccine

por Seid, Christopher A, Curti, Elena, Jones, R Mark, Hudspeth, Elissa, Rezende, Wanderson, Pollet, Jeroen, Center, Lori, Versteeg, Leroy, Pritchard, Sonya, Musiychuk, Konstantin, Yusibov, Vidadi, Hotez, Peter J, Bottazzi, Maria Elena
Publicado 2015

Controlled Human Hookworm Infection: Accelerating Human Hookworm Vaccine Development

por Diemert, David, Campbell, Doreen, Brelsford, Jill, Leasure, Caitlyn, Li, Guangzhao, Peng, Jin, Zumer, Maria, Younes, Naji, Bottazzi, Maria Elena, Mejia, Rojelio, Pritchard, David I, Hawdon, John M, Bethony, Jeffrey M
Publicado 2018

Mucosal Vaccination With Recombinant Tm-WAP49 Protein Induces Protective Humoral and Cellular Immunity Against Experimental Trichuriasis in AKR Mice

por Wei, Junfei, Hegde, Venkatesh L., Yanamandra, Ananta V., O’Hara, Madison P., Keegan, Brian, Jones, Kathryn M., Strych, Ulrich, Bottazzi, Maria Elena, Zhan, Bin, Sastry, K. Jagannadha, Hotez, Peter J.
Publicado 2022

The BENEFIT Trial: Where Do We Go from Here?

por Pecoul, Bernard, Batista, Carolina, Stobbaerts, Eric, Ribeiro, Isabella, Vilasanjuan, Rafael, Gascon, Joaquim, Pinazo, Maria Jesus, Moriana, Silvia, Gold, Silvia, Pereiro, Ana, Navarro, Miriam, Torrico, Faustino, Bottazzi, Maria Elena, Hotez, Peter J.
Publicado 2016

The Benefits of Vaccinating With the First Available COVID-19 Coronavirus Vaccine

por Bartsch, Sarah M., O'Shea, Kelly J., Wedlock, Patrick T., Strych, Ulrich, Ferguson, Marie C., Bottazzi, Maria Elena, Randall, Samuel L., Siegmund, Sheryl S., Cox, Sarah N., Hotez, Peter J., Lee, Bruce Y.
Publicado 2021

Lives and Costs Saved by Expanding and Expediting Coronavirus Disease 2019 Vaccination

por Bartsch, Sarah M, Wedlock, Patrick T, O’Shea, Kelly J, Cox, Sarah N, Strych, Ulrich, Nuzzo, Jennifer B, Ferguson, Marie C, Bottazzi, Maria Elena, Siegmund, Sheryl S, Hotez, Peter J, Lee, Bruce Y
Publicado 2021

Maintaining face mask use before and after achieving different COVID-19 vaccination coverage levels: a modelling study

por Bartsch, Sarah M, O'Shea, Kelly J, Chin, Kevin L, Strych, Ulrich, Ferguson, Marie C, Bottazzi, Maria Elena, Wedlock, Patrick T, Cox, Sarah N, Siegmund, Sheryl S, Hotez, Peter J, Lee, Bruce Y
Publicado 2022

Vaccine-linked chemotherapy improves cardiac structure and function in a mouse model of chronic Chagas disease

por Jones, Kathryn M., Mangin, Elise N., Reynolds, Corey L., Villanueva, Liliana E., Cruz, Julio Vladimir, Versteeg, Leroy, Keegan, Brian, Kendricks, April, Pollet, Jeroen, Gusovsky, Fabian, Bottazzi, Maria Elena, Hotez, Peter J.
Publicado 2023

Yeast-expressed recombinant As16 protects mice against Ascaris suum infection through induction of a Th2-skewed immune response

por Wei, Junfei, Versteeg, Leroy, Liu, Zhuyun, Keegan, Brian, Gazzinelli-Guimarães, Ana Clara, Fujiwara, Ricardo T., Briggs, Neima, Jones, Kathryn M., Strych, Ulrich, Beaumier, Coreen M., Bottazzi, Maria Elena, Hotez, Peter J., Zhan, Bin
Publicado 2017

Yeast-Expressed SARS-CoV Recombinant Receptor-Binding Domain (RBD219-N1) Formulated with Aluminum Hydroxide Induces Protective Immunity and Reduces Immune Enhancement

por Chen, Wen-Hsiang, Tao, Xinrong, Agrawal, Anurodh, Algaissi, Abdullah, Peng, Bi-Hung, Pollet, Jeroen, Strych, Ulrich, Bottazzi, Maria Elena, Hotez, Peter J., Lustigman, Sara, Du, Lanying, Jiang, Shibo, Tseng, Chien-Te K.
Publicado 2020

Vaccine Efficacy Needed for a COVID-19 Coronavirus Vaccine to Prevent or Stop an Epidemic as the Sole Intervention

por Bartsch, Sarah M., O'Shea, Kelly J., Ferguson, Marie C., Bottazzi, Maria Elena, Wedlock, Patrick T., Strych, Ulrich, McKinnell, James A., Siegmund, Sheryl S., Cox, Sarah N., Hotez, Peter J., Lee, Bruce Y.
Publicado 2020

Yeast-expressed SARS-CoV recombinant receptor-binding domain (RBD219-N1) formulated with aluminum hydroxide induces protective immunity and reduces immune enhancement

por Chen, Wen-Hsiang, Tao, Xinrong, Agrawal, Anurodh Shankar, Algaissi, Abdullah, Peng, Bi-Hung, Pollet, Jeroen, Strych, Ulrich, Bottazzi, Maria Elena, Hotez, Peter J., Lustigman, Sara, Du, Lanying, Jiang, Shibo, Tseng, Chien-Te K.
Publicado 2020

Vaccine-linked chemotherapy induces IL-17 production and reduces cardiac pathology during acute Trypanosoma cruzi infection

por Cruz-Chan, Julio V., Villanueva-Lizama, Liliana E., Versteeg, Leroy, Damania, Ashish, Villar, Maria José, González-López, Cristina, Keegan, Brian, Pollet, Jeroen, Gusovsky, Fabian, Hotez, Peter J., Bottazzi, Maria Elena, Jones, Kathryn M.
Publicado 2021

Onchocerca volvulus bivalent subunit vaccine induces protective immunity in genetically diverse collaborative cross recombinant inbred intercross mice

por Ryan, Nathan M., Hess, Jessica A., de Villena, Fernando Pardo-Manuel, Leiby, Benjamin E., Shimada, Ayako, Yu, Lei, Yarmahmoodi, Amir, Petrovsky, Nikolai, Zhan, Bin, Bottazzi, Maria Elena, Makepeace, Benjamin L., Lustigman, Sara, Abraham, David
Publicado 2021

Engineering a stable CHO cell line for the expression of a MERS-coronavirus vaccine antigen

por Nyon, Mun Peak, Du, Lanying, Tseng, Chien-Te Kent, Seid, Christopher A., Pollet, Jeroen, Naceanceno, Kevin S., Agrawal, Anurodh, Algaissi, Abdullah, Peng, Bi-Hung, Tai, Wanbo, Jiang, Shibo, Bottazzi, Maria Elena, Strych, Ulrich, Hotez, Peter J.
Publicado 2018

Trichuris muris whey acidic protein induces type 2 protective immunity against whipworm

por Briggs, Neima, Wei, Junfei, Versteeg, Leroy, Zhan, Bin, Keegan, Brian, Damania, Ashish, Pollet, Jeroen, Hayes, Kelly S., Beaumier, Coreen, Seid, Christopher A., Leong, Jamie, Grencis, Richard K., Bottazzi, Maria Elena, Sastry, K. Jagannadha, Hotez, Peter J.
Publicado 2018