A Genome-Wide Association Study Reveals Variants in ARL15 that Influence Adiponectin Levels

por Richards, J. Brent, Waterworth, Dawn, O'Rahilly, Stephen, Hivert, Marie-France, Loos, Ruth J. F., Perry, John R. B., Tanaka, Toshiko, Timpson, Nicholas John, Semple, Robert K., Soranzo, Nicole, Song, Kijoung, Rocha, Nuno, Grundberg, Elin, Dupuis, Josée, Florez, Jose C., Langenberg, Claudia, Prokopenko, Inga, Saxena, Richa, Sladek, Robert, Aulchenko, Yurii, Evans, David, Waeber, Gerard, Erdmann, Jeanette, Burnett, Mary-Susan, Sattar, Naveed, Devaney, Joseph, Willenborg, Christina, Hingorani, Aroon, Witteman, Jaquelin C. M., Vollenweider, Peter, Glaser, Beate, Hengstenberg, Christian, Ferrucci, Luigi, Melzer, David, Stark, Klaus, Deanfield, John, Winogradow, Janina, Grassl, Martina, Hall, Alistair S., Egan, Josephine M., Thompson, John R., Ricketts, Sally L., König, Inke R., Reinhard, Wibke, Grundy, Scott, Wichmann, H-Erich, Barter, Phil, Mahley, Robert, Kesaniemi, Y. Antero, Rader, Daniel J., Reilly, Muredach P., Epstein, Stephen E., Stewart, Alexandre F. R., Van Duijn, Cornelia M., Schunkert, Heribert, Burling, Keith, Deloukas, Panos, Pastinen, Tomi, Samani, Nilesh J., McPherson, Ruth, Davey Smith, George, Frayling, Timothy M., Wareham, Nicholas J., Meigs, James B., Mooser, Vincent, Spector, Tim D.
Publicado 2009

Detailed Physiologic Characterization Reveals Diverse Mechanisms for Novel Genetic Loci Regulating Glucose and Insulin Metabolism in Humans

por Ingelsson, Erik, Langenberg, Claudia, Hivert, Marie-France, Prokopenko, Inga, Lyssenko, Valeriya, Dupuis, Josée, Mägi, Reedik, Sharp, Stephen, Jackson, Anne U., Assimes, Themistocles L., Shrader, Peter, Knowles, Joshua W., Zethelius, Björn, Abbasi, Fahim A., Bergman, Richard N., Bergmann, Antje, Berne, Christian, Boehnke, Michael, Bonnycastle, Lori L., Bornstein, Stefan R., Buchanan, Thomas A., Bumpstead, Suzannah J., Böttcher, Yvonne, Chines, Peter, Collins, Francis S., Cooper, Cyrus C., Dennison, Elaine M., Erdos, Michael R., Ferrannini, Ele, Fox, Caroline S., Graessler, Jürgen, Hao, Ke, Isomaa, Bo, Jameson, Karen A., Kovacs, Peter, Kuusisto, Johanna, Laakso, Markku, Ladenvall, Claes, Mohlke, Karen L., Morken, Mario A., Narisu, Narisu, Nathan, David M., Pascoe, Laura, Payne, Felicity, Petrie, John R., Sayer, Avan A., Schwarz, Peter E. H., Scott, Laura J., Stringham, Heather M., Stumvoll, Michael, Swift, Amy J., Syvänen, Ann-Christine, Tuomi, Tiinamaija, Tuomilehto, Jaakko, Tönjes, Anke, Valle, Timo T., Williams, Gordon H., Lind, Lars, Barroso, Inês, Quertermous, Thomas, Walker, Mark, Wareham, Nicholas J., Meigs, James B., McCarthy, Mark I., Groop, Leif, Watanabe, Richard M., Florez, Jose C.
Publicado 2010

Impact of Type 2 Diabetes Susceptibility Variants on Quantitative Glycemic Traits Reveals Mechanistic Heterogeneity

por Dimas, Antigone S., Lagou, Vasiliki, Barker, Adam, Knowles, Joshua W., Mägi, Reedik, Hivert, Marie-France, Benazzo, Andrea, Rybin, Denis, Jackson, Anne U., Stringham, Heather M., Song, Ci, Fischer-Rosinsky, Antje, Boesgaard, Trine Welløv, Grarup, Niels, Abbasi, Fahim A., Assimes, Themistocles L., Hao, Ke, Yang, Xia, Lecoeur, Cécile, Barroso, Inês, Bonnycastle, Lori L., Böttcher, Yvonne, Bumpstead, Suzannah, Chines, Peter S., Erdos, Michael R., Graessler, Jurgen, Kovacs, Peter, Morken, Mario A., Narisu, Narisu, Payne, Felicity, Stancakova, Alena, Swift, Amy J., Tönjes, Anke, Bornstein, Stefan R., Cauchi, Stéphane, Froguel, Philippe, Meyre, David, Schwarz, Peter E.H., Häring, Hans-Ulrich, Smith, Ulf, Boehnke, Michael, Bergman, Richard N., Collins, Francis S., Mohlke, Karen L., Tuomilehto, Jaakko, Quertemous, Thomas, Lind, Lars, Hansen, Torben, Pedersen, Oluf, Walker, Mark, Pfeiffer, Andreas F.H., Spranger, Joachim, Stumvoll, Michael, Meigs, James B., Wareham, Nicholas J., Kuusisto, Johanna, Laakso, Markku, Langenberg, Claudia, Dupuis, Josée, Watanabe, Richard M., Florez, Jose C., Ingelsson, Erik, McCarthy, Mark I., Prokopenko, Inga
Publicado 2014

Evaluation in usual practice of the bevacizumab-FOLFIRI combination for the first-line treatment of patients with unresectable metastatic colorectal cancer treated in 2006: focus o...

por Metges, J. P., Lebot, M. A., Faroux, R., Riaud, F., Gamelin, E., Capitain, O., Guérin Meyer, V., Leynia, P., Douillard, J. Y., Senellart, H., Rochard, S., Louvigné, C., Campion, L., Dupuis, O., Grollier, C., Achour, N. A., Person, B., Raoul, J. L., Boucher, E., Bertrand, C., Ramée, J. F., Guivarch, L., Etienne, P. L., Roussel, S., Desclos, H., Julien, M. N., Labarre, M. I., Klein, V., Bessard, R., Stampfli, C., Royet, F., Faycal, J., Gouva, S., Le Bihan, G., Couturier, M., Gourlaouen, A., Bertholom, C., Porneuf, M., Jobard, E., Peguet, E., Grasset, D., Bouret, J. F., Bicheler, V., Ulvoas, A., Miglianico, L., Chouzenoux, C., Deguiral, P., Derenne, L., Martin, D., Langlet, P. Michel, Bodin, C., Rossi, V., Barré, S., Cojocarasu, O., Naveau Ploux, C., Vidal, A. M., Cumin, I., Egreteau, J., Brouard, A., Matysiak Budnik, T., Thomaré, P., Le Bris Michel, A. S., Piriou, G., Largeau, R., Elhannani, C., Crespeau, E., Suberville, F., Bourgeois, H., Riche, C., Lagadec, D. Déniel, Marhuenda, F., Grudé, F.
Publicado 2014

An integrative cross-omics analysis of DNA methylation sites of glucose and insulin homeostasis

por Liu, Jun, Carnero-Montoro, Elena, van Dongen, Jenny, Lent, Samantha, Nedeljkovic, Ivana, Ligthart, Symen, Tsai, Pei-Chien, Martin, Tiphaine C., Mandaviya, Pooja R., Jansen, Rick, Peters, Marjolein J., Duijts, Liesbeth, Jaddoe, Vincent W. V., Tiemeier, Henning, Felix, Janine F., Willemsen, Gonneke, de Geus, Eco J. C., Chu, Audrey Y., Levy, Daniel, Hwang, Shih-Jen, Bressler, Jan, Gondalia, Rahul, Salfati, Elias L., Herder, Christian, Hidalgo, Bertha A., Tanaka, Toshiko, Moore, Ann Zenobia, Lemaitre, Rozenn N., Jhun, Min A, Smith, Jennifer A., Sotoodehnia, Nona, Bandinelli, Stefania, Ferrucci, Luigi, Arnett, Donna K., Grallert, Harald, Assimes, Themistocles L., Hou, Lifang, Baccarelli, Andrea, Whitsel, Eric A., van Dijk, Ko Willems, Amin, Najaf, Uitterlinden, André G., Sijbrands, Eric J. G., Franco, Oscar H., Dehghan, Abbas, Spector, Tim D., Dupuis, Josée, Hivert, Marie-France, Rotter, Jerome I., Meigs, James B., Pankow, James S., van Meurs, Joyce B. J., Isaacs, Aaron, Boomsma, Dorret I., Bell, Jordana T., Demirkan, Ayşe, van Duijn, Cornelia M.
Publicado 2019

Sugar-Sweetened Beverage Consumption May Modify Associations Between Genetic Variants in the CHREBP (Carbohydrate Responsive Element Binding Protein) Locus and HDL-C (High-Density...

por Haslam, Danielle E., Peloso, Gina M., Guirette, Melanie, Imamura, Fumiaki, Bartz, Traci M., Pitsillides, Achilleas N., Wang, Carol A., Li-Gao, Ruifang, Westra, Jason M., Pitkänen, Niina, Young, Kristin L., Graff, Mariaelisa, Wood, Alexis C., Braun, Kim V.E., Luan, Jian’an, Kähönen, Mika, Kiefte-de Jong, Jessica C., Ghanbari, Mohsen, Tintle, Nathan, Lemaitre, Rozenn N., Mook-Kanamori, Dennis O., North, Kari, Helminen, Mika, Mossavar-Rahmani, Yasmin, Snetselaar, Linda, Martin, Lisa W., Viikari, Jorma S., Oddy, Wendy H., Pennell, Craig E., Rosendall, Frits R., Ikram, M. Arfan, Uitterlinden, Andre G, Psaty, Bruce M., Mozaffarian, Dariush, Rotter, Jerome I., Taylor, Kent D., Lehtimäki, Terho, Raitakari, Olli T., Livingston, Kara A., Voortman, Trudy, Forouhi, Nita G., Wareham, Nick J., de Mutsert, Renée, Rich, Steven S., Manson, JoAnn E., Mora, Samia, Ridker, Paul M., Merino, Jordi, Meigs, James B., Dashti, Hassan S., Chasman, Daniel I., Lichtenstein, Alice H., Smith, Caren E., Dupuis, Josée, Herman, Mark A., McKeown, Nicola M.
Publicado 2021

The Serological Sciences Network (SeroNet) for COVID-19: Depth and Breadth of Serology Assays and Plans for Assay Harmonization

por Karger, Amy B., Brien, James D., Christen, Jayne M., Dhakal, Santosh, Kemp, Troy J., Klein, Sabra L., Pinto, Ligia A., Premkumar, Lakshmanane, Roback, John D., Binder, Raquel A., Boehme, Karl W., Boppana, Suresh, Cordon-Cardo, Carlos, Crawford, James M., Daiss, John L., Dupuis, Alan P., Espino, Ana M., Firpo-Betancourt, Adolfo, Forconi, Catherine, Forrest, J. Craig, Girardin, Roxie C., Granger, Douglas A., Granger, Steve W., Haddad, Natalie S., Heaney, Christopher D., Hunt, Danielle T., Kennedy, Joshua L., King, Christopher L., Krammer, Florian, Kruczynski, Kate, LaBaer, Joshua, Lee, F. Eun-Hyung, Lee, William T., Liu, Shan-Lu, Lozanski, Gerard, Lucas, Todd, Mendu, Damodara Rao, Moormann, Ann M., Murugan, Vel, Okoye, Nkemakonam C., Pantoja, Petraleigh, Payne, Anne F., Park, Jin, Pinninti, Swetha, Pinto, Amelia K., Pisanic, Nora, Qiu, Ji, Sariol, Carlos A., Simon, Viviana, Song, Lusheng, Steffen, Tara L., Stone, E. Taylor, Styer, Linda M., Suthar, Mehul S., Thomas, Stefani N., Thyagarajan, Bharat, Wajnberg, Ania, Yates, Jennifer L., Sobhani, Kimia
Publicado 2022

The Serological Sciences Network (SeroNet) for COVID-19: Depth and Breadth of Serology Assays and Plans for Assay Harmonization

por Karger, Amy B., Brien, James D., Christen, Jayne M., Dhakal, Santosh, Kemp, Troy J., Klein, Sabra L., Pinto, Ligia A., Premkumar, Lakshmanane, Roback, John D., Binder, Raquel A., Boehme, Karl W., Boppana, Suresh, Cordon-Cardo, Carlos, Crawford, James M., Daiss, John L., Dupuis, Alan P., Espino, Ana M., Firpo-Betancourt, Adolfo, Forconi, Catherine, Forrest, J. Craig, Girardin, Roxie C., Granger, Douglas A., Granger, Steve W., Haddad, Natalie S., Heaney, Christopher D., Hunt, Danielle T., Kennedy, Joshua L., King, Christopher L., Krammer, Florian, Kruczynski, Kate, LaBaer, Joshua, Lee, F. Eun-Hyung, Lee, William T., Liu, Shan-Lu, Lozanski, Gerard, Lucas, Todd, Mendu, Damodara Rao, Moormann, Ann M., Murugan, Vel, Okoye, Nkemakonam C., Pantoja, Petraleigh, Payne, Anne F., Park, Jin, Pinninti, Swetha, Pinto, Amelia K., Pisanic, Nora, Qiu, Ji, Sariol, Carlos A., Simon, Viviana, Song, Lusheng, Steffen, Tara L., Stone, E. Taylor, Styer, Linda M., Suthar, Mehul S., Thomas, Stefani N., Thyagarajan, Bharat, Wajnberg, Ania, Yates, Jennifer L., Sobhani, Kimia
Publicado 2022

Impaired IL-23–dependent induction of IFN-γ underlies mycobacterial disease in patients with inherited TYK2 deficiency

por Ogishi, Masato, Arias, Andrés Augusto, Yang, Rui, Han, Ji Eun, Zhang, Peng, Rinchai, Darawan, Halpern, Joshua, Mulwa, Jeanette, Keating, Narelle, Chrabieh, Maya, Lainé, Candice, Seeleuthner, Yoann, Ramírez-Alejo, Noé, Nekooie-Marnany, Nioosha, Guennoun, Andrea, Muller-Fleckenstein, Ingrid, Fleckenstein, Bernhard, Kilic, Sara S., Minegishi, Yoshiyuki, Ehl, Stephan, Kaiser-Labusch, Petra, Kendir-Demirkol, Yasemin, Rozenberg, Flore, Errami, Abderrahmane, Zhang, Shen-Ying, Zhang, Qian, Bohlen, Jonathan, Philippot, Quentin, Puel, Anne, Jouanguy, Emmanuelle, Pourmoghaddas, Zahra, Bakhtiar, Shahrzad, Willasch, Andre M., Horneff, Gerd, Llanora, Genevieve, Shek, Lynette P., Chai, Louis Y.A., Tay, Sen Hee, Rahimi, Hamid H., Mahdaviani, Seyed Alireza, Nepesov, Serdar, Bousfiha, Aziz A., Erdeniz, Emine Hafize, Karbuz, Adem, Marr, Nico, Navarrete, Carmen, Adeli, Mehdi, Hammarstrom, Lennart, Abolhassani, Hassan, Parvaneh, Nima, Al Muhsen, Saleh, Alosaimi, Mohammed F., Alsohime, Fahad, Nourizadeh, Maryam, Moin, Mostafa, Arnaout, Rand, Alshareef, Saad, El-Baghdadi, Jamila, Genel, Ferah, Sherkat, Roya, Kiykim, Ayça, Yücel, Esra, Keles, Sevgi, Bustamante, Jacinta, Abel, Laurent, Casanova, Jean-Laurent, Boisson-Dupuis, Stéphanie
Publicado 2022

Time-to-Event Genome-Wide Association Study for Incident Cardiovascular Disease in People with Type 2 Diabetes Mellitus

por Kwak, Soo Heon, Hernandez-Cancela, Ryan B., DiCorpo, Daniel A, Condon, David E., Merino, Jordi, Wu, Peitao, Brody, Jennifer A, Yao, Jie, Guo, Xiuqing, Ahmadizar, Fariba, Meyer, Mariah, Sincan, Murat, Mercader, Josep M., Lee, Sujin, Haessler, Jeffrey, Vy, Ha My T., Lin, Zhaotong, Armstrong, Nicole D., Gu, Shaopeng, Tsao, Noah L., Lange, Leslie A., Wang, Ningyuan, Wiggins, Kerri L., Trompet, Stella, Liu, Simin, Loos, Ruth J.F., Judy, Renae, Schroeder, Philip H., Hasbani, Natalie R., Bos, Maxime M., Morrison, Alanna C., Jackson, Rebecca D., Reiner, Alexander P., Manson, JoAnn E., Chaudhary, Ninad S., Carmichael, Lynn K., Chen, Yii-Der Ida, Taylor, Kent D., Ghanbari, Mohsen, van Meurs, Joyce, Pitsillides, Achilleas N, Psaty, Bruce M., Noordam, Raymond, Do, Ron, Park, Kyong Soo, Jukema, J Wouter, Kavousi, Maryam, Correa, Adolfo, Rich, Stephen S., Damrauer, Scott M., Hajek, Catherine, Cho, Nam H., Irvin, Marguerite R., Pankow, James S., Nadkarni, Girish N., Sladek, Robert, Goodarzi, Mark O., Florez, Jose C., Chasman, Daniel I., Heckbert, Susan R., Kooperberg, Charles, Dupuis, Josée, Malhotra, Rajeev, de Vries, Paul S., Liu, Ching-Ti, Rotter, Jerome I., Meigs, James B.
Publicado 2023

Stratifying Type 2 Diabetes Cases by BMI Identifies Genetic Risk Variants in LAMA1 and Enrichment for Risk Variants in Lean Compared to Obese Cases

por Perry, John R. B., Voight, Benjamin F., Yengo, Loïc, Amin, Najaf, Dupuis, Josée, Ganser, Martha, Grallert, Harald, Navarro, Pau, Li, Man, Qi, Lu, Steinthorsdottir, Valgerdur, Scott, Robert A., Almgren, Peter, Arking, Dan E., Aulchenko, Yurii, Balkau, Beverley, Benediktsson, Rafn, Bergman, Richard N., Boerwinkle, Eric, Bonnycastle, Lori, Burtt, Noël P., Campbell, Harry, Charpentier, Guillaume, Collins, Francis S., Gieger, Christian, Green, Todd, Hadjadj, Samy, Hattersley, Andrew T., Herder, Christian, Hofman, Albert, Johnson, Andrew D., Kottgen, Anna, Kraft, Peter, Labrune, Yann, Langenberg, Claudia, Manning, Alisa K., Mohlke, Karen L., Morris, Andrew P., Oostra, Ben, Pankow, James, Petersen, Ann-Kristin, Pramstaller, Peter P., Prokopenko, Inga, Rathmann, Wolfgang, Rayner, William, Roden, Michael, Rudan, Igor, Rybin, Denis, Scott, Laura J., Sigurdsson, Gunnar, Sladek, Rob, Thorleifsson, Gudmar, Thorsteinsdottir, Unnur, Tuomilehto, Jaakko, Uitterlinden, Andre G., Vivequin, Sidonie, Weedon, Michael N., Wright, Alan F., Hu, Frank B., Illig, Thomas, Kao, Linda, Meigs, James B., Wilson, James F., Stefansson, Kari, van Duijn, Cornelia, Altschuler, David, Morris, Andrew D., Boehnke, Michael, McCarthy, Mark I., Froguel, Philippe, Palmer, Colin N. A., Wareham, Nicholas J., Groop, Leif, Frayling, Timothy M., Cauchi, Stéphane
Publicado 2012

Quality of dietary fat and genetic risk of type 2 diabetes: individual participant data meta-analysis

por Merino, Jordi, Guasch-Ferré, Marta, Ellervik, Christina, Dashti, Hassan S, Sharp, Stephen J, Wu, Peitao, Overvad, Kim, Sarnowski, Chloé, Kuokkanen, Mikko, Lemaitre, Rozenn N, Justice, Anne E, Ericson, Ulrika, Braun, Kim V E, Mahendran, Yuvaraj, Frazier-Wood, Alexis C, Sun, Dianjianyi, Chu, Audrey Y, Tanaka, Toshiko, Luan, Jian’an, Hong, Jaeyoung, Tjønneland, Anne, Ding, Ming, Lundqvist, Annamari, Mukamal, Kenneth, Rohde, Rebecca, Schulz, Christina-Alexandra, Franco, Oscar H, Grarup, Niels, Chen, Yii-Der Ida, Bazzano, Lydia, Franks, Paul W, Buring, Julie E, Langenberg, Claudia, Liu, Ching-Ti, Hansen, Torben, Jensen, Majken K, Sääksjärvi, Katri, Psaty, Bruce M, Young, Kristin L, Hindy, George, Sandholt, Camilla Helene, Ridker, Paul M, Ordovas, Jose M, Meigs, James B, Pedersen, Oluf, Kraft, Peter, Perola, Markus, North, Kari E, Orho-Melander, Marju, Voortman, Trudy, Toft, Ulla, Rotter, Jerome I, Qi, Lu, Forouhi, Nita G, Mozaffarian, Dariush, Sørensen, Thorkild I A, Stampfer, Meir J, Männistö, Satu, Selvin, Elizabeth, Imamura, Fumiaki, Salomaa, Veikko, Hu, Frank B, Wareham, Nick J, Dupuis, Josée, Smith, Caren E, Kilpeläinen, Tuomas O, Chasman, Daniel I, Florez, Jose C
Publicado 2019

Whole genome sequence analysis of pulmonary function and COPD in 19,996 multi-ethnic participants

por Zhao, Xutong, Qiao, Dandi, Yang, Chaojie, Kasela, Silva, Kim, Wonji, Ma, Yanlin, Shrine, Nick, Batini, Chiara, Sofer, Tamar, Taliun, Sarah A. Gagliano, Sakornsakolpat, Phuwanat, Balte, Pallavi P., Prokopenko, Dmitry, Yu, Bing, Lange, Leslie A., Dupuis, Josée, Cade, Brian E., Lee, Jiwon, Gharib, Sina A., Daya, Michelle, Laurie, Cecelia A., Ruczinski, Ingo, Cupples, L. Adrienne, Loehr, Laura R., Bartz, Traci M., Morrison, Alanna C., Psaty, Bruce M., Vasan, Ramachandran S., Wilson, James G., Taylor, Kent D., Durda, Peter, Johnson, W. Craig, Cornell, Elaine, Guo, Xiuqing, Liu, Yongmei, Tracy, Russell P., Ardlie, Kristin G., Aguet, François, VanDenBerg, David J., Papanicolaou, George J., Rotter, Jerome I., Barnes, Kathleen C., Jain, Deepti, Nickerson, Deborah A., Muzny, Donna M., Metcalf, Ginger A., Doddapaneni, Harshavardhan, Dugan-Perez, Shannon, Gupta, Namrata, Gabriel, Stacey, Rich, Stephen S., O’Connor, George T., Redline, Susan, Reed, Robert M., Laurie, Cathy C., Daviglus, Martha L., Preudhomme, Liana K., Burkart, Kristin M., Kaplan, Robert C., Wain, Louise V., Tobin, Martin D., London, Stephanie J., Lappalainen, Tuuli, Oelsner, Elizabeth C., Abecasis, Goncalo R., Silverman, Edwin K., Barr, R. Graham, Cho, Michael H., Manichaikul, Ani
Publicado 2020

Pulmonary Function and Blood DNA Methylation: A Multiancestry Epigenome-Wide Association Meta-analysis

por Lee, Mikyeong, Huan, Tianxiao, McCartney, Daniel L., Chittoor, Geetha, de Vries, Maaike, Lahousse, Lies, Nguyen, Jennifer N., Brody, Jennifer A., Castillo-Fernandez, Juan, Terzikhan, Natalie, Qi, Cancan, Joehanes, Roby, Min, Josine L., Smilnak, Gordon J., Shaw, Jessica R., Yang, Chen Xi, Colicino, Elena, Hoang, Thanh T., Bermingham, Mairead L., Xu, Hanfei, Justice, Anne E., Xu, Cheng-Jian, Rich, Stephen S., Cox, Simon R., Vonk, Judith M., Prokić, Ivana, Sotoodehnia, Nona, Tsai, Pei-Chien, Schwartz, Joel D., Leung, Janice M., Sikdar, Sinjini, Walker, Rosie M., Harris, Sarah E., van der Plaat, Diana A., Van Den Berg, David J., Bartz, Traci M., Spector, Tim D., Vokonas, Pantel S., Marioni, Riccardo E., Taylor, Adele M., Liu, Yongmei, Barr, R. Graham, Lange, Leslie A., Baccarelli, Andrea A., Obeidat, Ma’en, Fornage, Myriam, Wang, Tianyuan, Ward, James M., Motsinger-Reif, Alison A., Hemani, Gibran, Koppelman, Gerard H., Bell, Jordana T., Gharib, Sina A., Brusselle, Guy, Boezen, H. Marike, North, Kari E., Levy, Daniel, Evans, Kathryn L., Dupuis, Josée, Breeze, Charles E., Manichaikul, Ani, London, Stephanie J.
Publicado 2022

Mendelian Randomization Studies Do Not Support a Causal Role for Reduced Circulating Adiponectin Levels in Insulin Resistance and Type 2 Diabetes

por Yaghootkar, Hanieh, Lamina, Claudia, Scott, Robert A., Dastani, Zari, Hivert, Marie-France, Warren, Liling L., Stancáková, Alena, Buxbaum, Sarah G., Lyytikäinen, Leo-Pekka, Henneman, Peter, Wu, Ying, Cheung, Chloe Y.Y., Pankow, James S., Jackson, Anne U., Gustafsson, Stefan, Zhao, Jing Hua, Ballantyne, Christie M., Xie, Weijia, Bergman, Richard N., Boehnke, Michael, el Bouazzaoui, Fatiha, Collins, Francis S., Dunn, Sandra H., Dupuis, Josee, Forouhi, Nita G., Gillson, Christopher, Hattersley, Andrew T., Hong, Jaeyoung, Kähönen, Mika, Kuusisto, Johanna, Kedenko, Lyudmyla, Kronenberg, Florian, Doria, Alessandro, Assimes, Themistocles L., Ferrannini, Ele, Hansen, Torben, Hao, Ke, Häring, Hans, Knowles, Joshua W., Lindgren, Cecilia M., Nolan, John J., Paananen, Jussi, Pedersen, Oluf, Quertermous, Thomas, Smith, Ulf, Lehtimäki, Terho, Liu, Ching-Ti, Loos, Ruth J.F., McCarthy, Mark I., Morris, Andrew D., Vasan, Ramachandran S., Spector, Tim D., Teslovich, Tanya M., Tuomilehto, Jaakko, van Dijk, Ko Willems, Viikari, Jorma S., Zhu, Na, Langenberg, Claudia, Ingelsson, Erik, Semple, Robert K., Sinaiko, Alan R., Palmer, Colin N.A., Walker, Mark, Lam, Karen S.L., Paulweber, Bernhard, Mohlke, Karen L., van Duijn, Cornelia, Raitakari, Olli T., Bidulescu, Aurelian, Wareham, Nick J., Laakso, Markku, Waterworth, Dawn M., Lawlor, Debbie A., Meigs, James B., Richards, J. Brent, Frayling, Timothy M.
Publicado 2013

A novel highly-penetrant form of obesity due to microdeletions on chromosome 16p11.2

por Walters, R. G., Jacquemont, S., Valsesia, A., de Smith, A. J., Martinet, D., Andersson, J., Falchi, M., Chen, F., Andrieux, J., Lobbens, S., Delobel, B., Stutzmann, F., Moustafa, J. S. El-Sayed, Chèvre, J.-C., Lecoeur, C., Vatin, V., Bouquillon, S., Buxton, J. L., Boute, O., Holder-Espinasse, M., Cuisset, J.-M., Lemaitre, M.-P., Ambresin, A.-E., Brioshi, A., Gaillard, M., Giusti, V., Fellmann, F., Ferrarini, A., Hadjikhani, N., Campion, D., Guilmatre, A., Goldenberg, A., Calmels, N., Mandel, J.-L., Le Caignec, C., David, A., Isidor, B., Cordier, M.-P., Dupuis-Girod, S., Labalme, A., Sanlaville, D., Béri-Deixheimer, M., Jonveaux, P., Leheup, B., Õunap, K., Bochukova, E. G., Henning, E., Keogh, J., Ellis, R. J., MacDermot, K. D., Vincent-Delorme, C., Plessis, G., Touraine, R., Philippe, A., Malan, V., Mathieu-Dramard, M., Chiesa, J., Blaumeiser, B., Kooy, R. F., Caiazzo, R., Pigeyre, M., Balkau, B., Sladek, R., Bergmann, S., Mooser, V., Waterworth, D., Reymond, A., Vollenweider, P., Waeber, G., Kurg, A., Palta, P., Esko, T., Metspalu, A., Nelis, M., Elliott, P., Hartikainen, A.-L., McCarthy, M. I., Peltonen, L., Carlsson, L., Jacobson, P., Sjöström, L., Huang, N., Hurles, M. E., O’Rahilly, S., Farooqi, I. S., Männik, K., Jarvelin, M.-R., Pattou, F., Meyre, D., Walley, A. J., Coin, L. J. M., Blakemore, A. I. F., Froguel, P., Beckmann, J. S.
Publicado 2010

Large-Scale Genome-Wide Association Studies and Meta-Analyses of Longitudinal Change in Adult Lung Function

por Tang, Wenbo, Kowgier, Matthew, Loth, Daan W., Soler Artigas, María, Joubert, Bonnie R., Hodge, Emily, Gharib, Sina A., Smith, Albert V., Ruczinski, Ingo, Gudnason, Vilmundur, Mathias, Rasika A., Harris, Tamara B., Hansel, Nadia N., Launer, Lenore J., Barnes, Kathleen C., Hansen, Joyanna G., Albrecht, Eva, Aldrich, Melinda C., Allerhand, Michael, Barr, R. Graham, Brusselle, Guy G., Couper, David J., Curjuric, Ivan, Davies, Gail, Deary, Ian J., Dupuis, Josée, Fall, Tove, Foy, Millennia, Franceschini, Nora, Gao, Wei, Gläser, Sven, Gu, Xiangjun, Hancock, Dana B., Heinrich, Joachim, Hofman, Albert, Imboden, Medea, Ingelsson, Erik, James, Alan, Karrasch, Stefan, Koch, Beate, Kritchevsky, Stephen B., Kumar, Ashish, Lahousse, Lies, Li, Guo, Lind, Lars, Lindgren, Cecilia, Liu, Yongmei, Lohman, Kurt, Lumley, Thomas, McArdle, Wendy L., Meibohm, Bernd, Morris, Andrew P., Morrison, Alanna C., Musk, Bill, North, Kari E., Palmer, Lyle J., Probst-Hensch, Nicole M., Psaty, Bruce M., Rivadeneira, Fernando, Rotter, Jerome I., Schulz, Holger, Smith, Lewis J., Sood, Akshay, Starr, John M., Strachan, David P., Teumer, Alexander, Uitterlinden, André G., Völzke, Henry, Voorman, Arend, Wain, Louise V., Wells, Martin T., Wilk, Jemma B., Williams, O. Dale, Heckbert, Susan R., Stricker, Bruno H., London, Stephanie J., Fornage, Myriam, Tobin, Martin D., O′Connor, George T., Hall, Ian P., Cassano, Patricia A.
Publicado 2014

Human IRF1 governs macrophagic IFN-γ immunity to mycobacteria

por Rosain, Jérémie, Neehus, Anna-Lena, Manry, Jeremy, Yang, Rui, Le Pen, Jérémie, Daher, Wassim, Liu, Zhiyong, Chan, Yi-Hao, Tahuil, Natalia, Türel, Özden, Bourgey, Mathieu, Ogishi, Masato, Doisne, Jean-Marc, Izquierdo, Helena M., Shirasaki, Takayoshi, Le Voyer, Tom, Guérin, Antoine, Bastard, Paul, Moncada-Velez, Marcela, Han, Ji Eun, Khan, Taushif, Rapaport, Franck, Hong, Seon-Hui, Cheung, Andrew, Haake, Kathrin, Mindt, Barbara C., Perez, Laura, Philippot, Quentin, Lee, Danyel, Zhang, Peng, Rinchai, Darawan, Al Ali, Fatima, Ata, Manar Mahmoud Ahmad, Rahman, Mahbuba, Peel, Jessica N., Heissel, Søren, Molina, Henrik, Kendir-Demirkol, Yasemin, Bailey, Rasheed, Zhao, Shuxiang, Bohlen, Jonathan, Mancini, Mathieu, Seeleuthner, Yoann, Roelens, Marie, Lorenzo, Lazaro, Soudée, Camille, Paz, María Elvira Josefina, Gonzalez, Maria Laura, Jeljeli, Mohamed, Soulier, Jean, Romana, Serge, L’Honneur, Anne-Sophie, Materna, Marie, Martínez-Barricarte, Rubén, Pochon, Mathieu, Oleaga-Quintas, Carmen, Michev, Alexandre, Migaud, Mélanie, Lévy, Romain, Alyanakian, Marie-Alexandra, Rozenberg, Flore, Croft, Carys A., Vogt, Guillaume, Emile, Jean-François, Kremer, Laurent, Ma, Cindy S., Fritz, Jörg H., Lemon, Stanley M., Spaan, András N., Manel, Nicolas, Abel, Laurent, MacDonald, Margaret R., Boisson-Dupuis, Stéphanie, Marr, Nico, Tangye, Stuart G., Di Santo, James P., Zhang, Qian, Zhang, Shen-Ying, Rice, Charles M., Béziat, Vivien, Lachmann, Nico, Langlais, David, Casanova, Jean-Laurent, Gros, Philippe, Bustamante, Jacinta
Publicado 2023

Identification and Functional Characterization of G6PC2 Coding Variants Influencing Glycemic Traits Define an Effector Transcript at the G6PC2-ABCB11 Locus

por Mahajan, Anubha, Sim, Xueling, Ng, Hui Jin, Manning, Alisa, Rivas, Manuel A., Highland, Heather M., Locke, Adam E., Grarup, Niels, Im, Hae Kyung, Cingolani, Pablo, Flannick, Jason, Fontanillas, Pierre, Fuchsberger, Christian, Gaulton, Kyle J., Teslovich, Tanya M., Rayner, N. William, Robertson, Neil R., Beer, Nicola L., Rundle, Jana K., Bork-Jensen, Jette, Ladenvall, Claes, Blancher, Christine, Buck, David, Buck, Gemma, Burtt, Noël P., Gabriel, Stacey, Gjesing, Anette P., Groves, Christopher J., Hollensted, Mette, Huyghe, Jeroen R., Jackson, Anne U., Jun, Goo, Justesen, Johanne Marie, Mangino, Massimo, Murphy, Jacquelyn, Neville, Matt, Onofrio, Robert, Small, Kerrin S., Stringham, Heather M., Syvänen, Ann-Christine, Trakalo, Joseph, Abecasis, Goncalo, Bell, Graeme I., Blangero, John, Cox, Nancy J., Duggirala, Ravindranath, Hanis, Craig L., Seielstad, Mark, Wilson, James G., Christensen, Cramer, Brandslund, Ivan, Rauramaa, Rainer, Surdulescu, Gabriela L., Doney, Alex S. F., Lannfelt, Lars, Linneberg, Allan, Isomaa, Bo, Tuomi, Tiinamaija, Jørgensen, Marit E., Jørgensen, Torben, Kuusisto, Johanna, Uusitupa, Matti, Salomaa, Veikko, Spector, Timothy D., Morris, Andrew D., Palmer, Colin N. A., Collins, Francis S., Mohlke, Karen L., Bergman, Richard N., Ingelsson, Erik, Lind, Lars, Tuomilehto, Jaakko, Hansen, Torben, Watanabe, Richard M., Prokopenko, Inga, Dupuis, Josee, Karpe, Fredrik, Groop, Leif, Laakso, Markku, Pedersen, Oluf, Florez, Jose C., Morris, Andrew P., Altshuler, David, Meigs, James B., Boehnke, Michael, McCarthy, Mark I., Lindgren, Cecilia M., Gloyn, Anna L.
Publicado 2015

DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases

por Ligthart, Symen, Marzi, Carola, Aslibekyan, Stella, Mendelson, Michael M., Conneely, Karen N., Tanaka, Toshiko, Colicino, Elena, Waite, Lindsay L., Joehanes, Roby, Guan, Weihua, Brody, Jennifer A., Elks, Cathy, Marioni, Riccardo, Jhun, Min A., Agha, Golareh, Bressler, Jan, Ward-Caviness, Cavin K., Chen, Brian H., Huan, Tianxiao, Bakulski, Kelly, Salfati, Elias L., Fiorito, Giovanni, Wahl, Simone, Schramm, Katharina, Sha, Jin, Hernandez, Dena G., Just, Allan C., Smith, Jennifer A., Sotoodehnia, Nona, Pilling, Luke C., Pankow, James S., Tsao, Phil S., Liu, Chunyu, Zhao, Wei, Guarrera, Simonetta, Michopoulos, Vasiliki J., Smith, Alicia K., Peters, Marjolein J., Melzer, David, Vokonas, Pantel, Fornage, Myriam, Prokisch, Holger, Bis, Joshua C., Chu, Audrey Y., Herder, Christian, Grallert, Harald, Yao, Chen, Shah, Sonia, McRae, Allan F., Lin, Honghuang, Horvath, Steve, Fallin, Daniele, Hofman, Albert, Wareham, Nicholas J., Wiggins, Kerri L., Feinberg, Andrew P., Starr, John M., Visscher, Peter M., Murabito, Joanne M., Kardia, Sharon L. R., Absher, Devin M., Binder, Elisabeth B., Singleton, Andrew B., Bandinelli, Stefania, Peters, Annette, Waldenberger, Melanie, Matullo, Giuseppe, Schwartz, Joel D., Demerath, Ellen W., Uitterlinden, André G., van Meurs, Joyce B. J., Franco, Oscar H., Chen, Yii-Der Ida, Levy, Daniel, Turner, Stephen T., Deary, Ian J., Ressler, Kerry J., Dupuis, Josée, Ferrucci, Luigi, Ong, Ken K., Assimes, Themistocles L., Boerwinkle, Eric, Koenig, Wolfgang, Arnett, Donna K., Baccarelli, Andrea A., Benjamin, Emelia J., Dehghan, Abbas
Publicado 2016