Protective activity of mRNA vaccines against ancestral and variant SARS-CoV-2 strains

por Ying, Baoling, Whitener, Bradley, VanBlargan, Laura A., Hassan, Ahmed O., Shrihari, Swathi, Liang, Chieh-Yu, Karl, Courtney E., Mackin, Samantha, Chen, Rita E., Kafai, Natasha M., Wilks, Samuel H., Smith, Derek J., Carreño, Juan Manuel, Singh, Gagandeep, Krammer, Florian, Carfi, Andrea, Elbashir, Sayda, Edwards, Darin K., Thackray, Larissa B., Diamond, Michael S.
Publicado 2021

Protective activity of mRNA vaccines against ancestral and variant SARS-CoV-2 strains

por Ying, Baoling, Whitener, Bradley, VanBlargan, Laura A., Hassan, Ahmed O., Shrihari, Swathi, Liang, Chieh-Yu, Karl, Courtney E., Mackin, Samantha, Chen, Rita E., Kafai, Natasha M., Wilks, Samuel H., Smith, Derek J., Carreño, Juan Manuel, Singh, Gagandeep, Krammer, Florian, Carfi, Andrea, Elbashir, Sayda M., Edwards, Darin K., Thackray, Larissa B., Diamond, Michael S.
Publicado 2021

Variant SARS-CoV-2 mRNA vaccines confer broad neutralization as primary or booster series in mice

por Wu, Kai, Choi, Angela, Koch, Matthew, Elbashir, Sayda, Ma, LingZhi, Lee, Diana, Woods, Angela, Henry, Carole, Palandjian, Charis, Hill, Anna, Jani, Hardik, Quinones, Julian, Nunna, Naveen, O'Connell, Sarah, McDermott, Adrian B., Falcone, Samantha, Narayanan, Elisabeth, Colpitts, Tonya, Bennett, Hamilton, Corbett, Kizzmekia S., Seder, Robert, Graham, Barney S., Stewart-Jones, Guillaume B.E., Carfi, Andrea, Edwards, Darin K.
Publicado 2021

Bivalent SARS-CoV-2 mRNA vaccines increase breadth of neutralization and protect against the BA.5 Omicron variant

por Scheaffer, Suzanne M., Lee, Diana, Whitener, Bradley, Ying, Baoling, Wu, Kai, Jani, Hardik, Martin, Philippa, Amato, Nicholas J., Avena, Laura E., Berrueta, Daniela Montes, Schmidt, Stephen D., O’Dell, Sijy, Nasir, Arshan, Chuang, Gwo-Yu, Stewart-Jones, Guillaume, Koup, Richard A., Doria-Rose, Nicole A., Carfi, Andrea, Elbashir, Sayda M., Thackray, Larissa B., Edwards, Darin K., Diamond, Michael S.
Publicado 2022

COVID-19 vaccine mRNA-1273 elicits a protective immune profile in mice that is not associated with vaccine-enhanced disease upon SARS-CoV-2 challenge

por DiPiazza, Anthony T., Leist, Sarah R., Abiona, Olubukola M., Moliva, Juan I., Werner, Anne, Minai, Mahnaz, Nagata, Bianca M., Bock, Kevin W., Phung, Emily, Schäfer, Alexandra, Dinnon, Kenneth H., Chang, Lauren A., Loomis, Rebecca J., Boyoglu-Barnum, Seyhan, Alvarado, Gabriela S., Sullivan, Nancy J., Edwards, Darin K., Morabito, Kaitlyn M., Mascola, John R., Carfi, Andrea, Corbett, Kizzmekia S., Moore, Ian N., Baric, Ralph S., Graham, Barney S., Ruckwardt, Tracy J.
Publicado 2021

SARS-CoV-2 vaccines elicit durable immune responses in infant rhesus macaques

por Garrido, Carolina, Curtis, Alan D., Dennis, Maria, Pathak, Sachi H., Gao, Hongmei, Montefiori, David, Tomai, Mark, Fox, Christopher B., Kozlowski, Pamela A., Scobey, Trevor, Munt, Jennifer E., Mallory, Michael L., Saha, Pooja T., Hudgens, Michael G., Lindesmith, Lisa C., Baric, Ralph S., Abiona, Olubukola M., Graham, Barney S., Corbett, Kizzmekia S., Edwards, Darin, Carfi, Andrea, Fouda, Genevieve, Van Rompay, Koen K. A., De Paris, Kristina, Permar, Sallie R.
Publicado 2021

Boosting with variant-matched or historical mRNA vaccines protects against Omicron infection in mice

por Ying, Baoling, Scheaffer, Suzanne M., Whitener, Bradley, Liang, Chieh-Yu, Dmytrenko, Oleksandr, Mackin, Samantha, Wu, Kai, Lee, Diana, Avena, Laura E., Chong, Zhenlu, Case, James Brett, Ma, LingZhi, Kim, Thu T.M., Sein, Caralyn E., Woods, Angela, Berrueta, Daniela Montes, Chang, Gwo-Yu, Stewart-Jones, Guillaume, Renzi, Isabella, Lai, Yen-Ting, Malinowski, Agata, Carfi, Andrea, Elbashir, Sayda M., Edwards, Darin K., Thackray, Larissa B., Diamond, Michael S.
Publicado 2022

Distinct sensitivities to SARS-CoV-2 variants in vaccinated humans and mice

por Walls, Alexandra C., VanBlargan, Laura A., Wu, Kai, Choi, Angela, Navarro, Mary Jane, Lee, Diana, Avena, Laura, Berrueta, Daniela Montes, Pham, Minh N., Elbashir, Sayda, Kraft, John C., Miranda, Marcos C., Kepl, Elizabeth, Johnson, Max, Blackstone, Alyssa, Sprouse, Kaitlin, Fiala, Brooke, O’Connor, Megan A., Brunette, Natalie, Arunachalam, Prabhu S., Shirreff, Lisa, Rogers, Kenneth, Carter, Lauren, Fuller, Deborah H., Villinger, Francois, Pulendran, Bali, Diamond, Michael S., Edwards, Darin K., King, Neil P., Veesler, David
Publicado 2022

Infant rhesus macaques immunized against SARS-CoV-2 are protected against heterologous virus challenge one year later

por Milligan, Emma C., Olstad, Katherine, Williams, Caitlin A., Mallory, Michael, Cano, Patricio, Cross, Kaitlyn A., Munt, Jennifer E., Garrido, Carolina, Lindesmith, Lisa, Watanabe, Jennifer, Usachenko, Jodie L., Hopkins, Lincoln, Immareddy, Ramya, Lakshmanappa, Yashavanth Shaan, Elizaldi, Sonny R., Roh, Jamin W., Sammak, Rebecca L., Pollard, Rachel E., Yee, JoAnn L., Herbek, Savannah, Scobey, Trevor, Miehlke, Dieter, Fouda, Genevieve, Ferrari, Guido, Gao, Hongmei, Shen, Xiaoying, Kozlowski, Pamela A., Montefiori, David, Hudgens, Michael G., Edwards, Darin K., Carfi, Andrea, Corbett, Kizzmekia S., Graham, Barney S., Fox, Christopher B., Tomai, Mark, Iyer, Smita S., Baric, Ralph, Reader, Rachel, Dittmer, Dirk P., Van Rompay, Koen K.A., Permar, Sallie R., De Paris, Kristina
Publicado 2022

SARS-CoV-2 Omicron Variant Neutralization after mRNA-1273 Booster Vaccination

por Pajon, Rolando, Doria-Rose, Nicole A., Shen, Xiaoying, Schmidt, Stephen D., O’Dell, Sijy, McDanal, Charlene, Feng, Wenhong, Tong, Jin, Eaton, Amanda, Maglinao, Maha, Tang, Haili, Manning, Kelly E., Edara, Venkata-Viswanadh, Lai, Lilin, Ellis, Madison, Moore, Kathryn M., Floyd, Katharine, Foster, Stephanie L., Posavad, Christine M., Atmar, Robert L., Lyke, Kirsten E., Zhou, Tongqing, Wang, Lingshu, Zhang, Yi, Gaudinski, Martin R., Black, Walker P., Gordon, Ingelise, Guech, Mercy, Ledgerwood, Julie E., Misasi, John N., Widge, Alicia, Sullivan, Nancy J., Roberts, Paul C., Beigel, John H., Korber, Bette, Baden, Lindsey R., El Sahly, Hana, Chalkias, Spyros, Zhou, Honghong, Feng, Jing, Girard, Bethany, Das, Rituparna, Aunins, Anne, Edwards, Darin K., Suthar, Mehul S., Mascola, John R., Montefiori, David C.
Publicado 2022

mRNA-1273 Protects against SARS-CoV-2 Beta Infection in Nonhuman Primates

por Corbett, Kizzmekia S., Werner, Anne P., O’ Connell, Sarah, Gagne, Matthew, Lai, Lilin, Moliva, Juan I., Flynn, Barbara, Choi, Angela, Koch, Matthew, Foulds, Kathryn E., Andrew, Shayne F., Flebbe, Dillon R., Lamb, Evan, Nurmukhambetova, Saule T., Provost, Samantha J., Bock, Kevin W., Minai, Mahnaz, Nagata, Bianca M., Van Ry, Alex, Flinchbaugh, Zackery, Johnston, Timothy S., Mokhtari, Elham Bayat, Mudvari, Prakriti, Henry, Amy R., Laboune, Farida, Chang, Becky, Porto, Maciel, Wear, Jaclyn, Alvarado, Gabriela S., Boyoglu-Barnum, Seyhan, Todd, John-Paul M., Bart, Bridget, Cook, Anthony, Dodson, Alan, Pessaint, Laurent, Steingrebe, Katelyn, Elbashir, Sayda, Sriparna, Manjari, Pekosz, Andrew, Andersen, Hanne, Wu, Kai, Edwards, Darin K., Kar, Swagata, Lewis, Mark G., Boritz, Eli, Moore, Ian N., Carfi, Andrea, Suthar, Mehul S., McDermott, Adrian, Roederer, Mario, Nason, Martha C., Sullivan, Nancy J., Douek, Daniel C., Graham, Barney S., Seder, Robert A.
Publicado 2021

Protection from SARS-CoV-2 Delta one year after mRNA-1273 vaccination in rhesus macaques coincides with anamnestic antibody response in the lung

por Gagne, Matthew, Corbett, Kizzmekia S., Flynn, Barbara J., Foulds, Kathryn E., Wagner, Danielle A., Andrew, Shayne F., Todd, John-Paul M., Honeycutt, Christopher Cole, McCormick, Lauren, Nurmukhambetova, Saule T., Davis-Gardner, Meredith E., Pessaint, Laurent, Bock, Kevin W., Nagata, Bianca M., Minai, Mahnaz, Werner, Anne P., Moliva, Juan I., Tucker, Courtney, Lorang, Cynthia G., Zhao, Bingchun, McCarthy, Elizabeth, Cook, Anthony, Dodson, Alan, Teng, I-Ting, Mudvari, Prakriti, Roberts-Torres, Jesmine, Laboune, Farida, Wang, Lingshu, Goode, Adrienne, Kar, Swagata, Boyoglu-Barnum, Seyhan, Yang, Eun Sung, Shi, Wei, Ploquin, Aurélie, Doria-Rose, Nicole, Carfi, Andrea, Mascola, John R., Boritz, Eli A., Edwards, Darin K., Andersen, Hanne, Lewis, Mark G., Suthar, Mehul S., Graham, Barney S., Roederer, Mario, Moore, Ian N., Nason, Martha C., Sullivan, Nancy J., Douek, Daniel C., Seder, Robert A.
Publicado 2022

SARS-CoV-2 mRNA Vaccine Design Enabled by Prototype Pathogen Preparedness

por Corbett, Kizzmekia S., Edwards, Darin K., Leist, Sarah R., Abiona, Olubukola M., Boyoglu-Barnum, Seyhan, Gillespie, Rebecca A., Himansu, Sunny, Schäfer, Alexandra, Ziwawo, Cynthia T., DiPiazza, Anthony T., Dinnon, Kenneth H., Elbashir, Sayda M., Shaw, Christine A., Woods, Angela, Fritch, Ethan J., Martinez, David R., Bock, Kevin W., Minai, Mahnaz, Nagata, Bianca M., Hutchinson, Geoffrey B., Wu, Kai, Henry, Carole, Bahi, Kapil, Garcia-Dominguez, Dario, Ma, LingZhi, Renzi, Isabella, Kong, Wing-Pui, Schmidt, Stephen D., Wang, Lingshu, Zhang, Yi, Phung, Emily, Chang, Lauren A., Loomis, Rebecca J., Altaras, Nedim Emil, Narayanan, Elisabeth, Metkar, Mihir, Presnyak, Vlad, Liu, Cuiping, Louder, Mark K., Shi, Wei, Leung, Kwanyee, Yang, Eun Sung, West, Ande, Gully, Kendra L., Stevens, Laura J., Wang, Nianshuang, Wrapp, Daniel, Doria-Rose, Nicole A., Stewart-Jones, Guillaume, Bennett, Hamilton, Alvarado, Gabriela S., Nason, Martha C., Ruckwardt, Tracy J., McLellan, Jason S., Denison, Mark R., Chappell, James D., Moore, Ian N., Morabito, Kaitlyn M., Mascola, John R., Baric, Ralph S., Carfi, Andrea, Graham, Barney S.
Publicado 2020

Evaluation of the mRNA-1273 Vaccine against SARS-CoV-2 in Nonhuman Primates

por Corbett, Kizzmekia S., Flynn, Barbara, Foulds, Kathryn E., Francica, Joseph R., Boyoglu-Barnum, Seyhan, Werner, Anne P., Flach, Britta, O’Connell, Sarah, Bock, Kevin W., Minai, Mahnaz, Nagata, Bianca M., Andersen, Hanne, Martinez, David R., Noe, Amy T., Douek, Naomi, Donaldson, Mitzi M., Nji, Nadesh N., Alvarado, Gabriela S., Edwards, Darin K., Flebbe, Dillon R., Lamb, Evan, Doria-Rose, Nicole A., Lin, Bob C., Louder, Mark K., O’Dell, Sijy, Schmidt, Stephen D., Phung, Emily, Chang, Lauren A., Yap, Christina, Todd, John-Paul M., Pessaint, Laurent, Van Ry, Alex, Browne, Shanai, Greenhouse, Jack, Putman-Taylor, Tammy, Strasbaugh, Amanda, Campbell, Tracey-Ann, Cook, Anthony, Dodson, Alan, Steingrebe, Katelyn, Shi, Wei, Zhang, Yi, Abiona, Olubukola M., Wang, Lingshu, Pegu, Amarendra, Yang, Eun Sung, Leung, Kwanyee, Zhou, Tongqing, Teng, I-Ting, Widge, Alicia, Gordon, Ingelise, Novik, Laura, Gillespie, Rebecca A., Loomis, Rebecca J., Moliva, Juan I., Stewart-Jones, Guillaume, Himansu, Sunny, Kong, Wing-Pui, Nason, Martha C., Morabito, Kaitlyn M., Ruckwardt, Tracy J., Ledgerwood, Julie E., Gaudinski, Martin R., Kwong, Peter D., Mascola, John R., Carfi, Andrea, Lewis, Mark G., Baric, Ralph S., McDermott, Adrian, Moore, Ian N., Sullivan, Nancy J., Roederer, Mario, Seder, Robert A., Graham, Barney S.
Publicado 2020

mRNA-1273 or mRNA-Omicron boost in vaccinated macaques elicits similar B cell expansion, neutralizing responses, and protection from Omicron

por Gagne, Matthew, Moliva, Juan I., Foulds, Kathryn E., Andrew, Shayne F., Flynn, Barbara J., Werner, Anne P., Wagner, Danielle A., Teng, I-Ting, Lin, Bob C., Moore, Christopher, Jean-Baptiste, Nazaire, Carroll, Robin, Foster, Stephanie L., Patel, Mit, Ellis, Madison, Edara, Venkata-Viswanadh, Maldonado, Nahara Vargas, Minai, Mahnaz, McCormick, Lauren, Honeycutt, Christopher Cole, Nagata, Bianca M., Bock, Kevin W., Dulan, Caitlyn N.M., Cordon, Jamilet, Flebbe, Dillon R., Todd, John-Paul M., McCarthy, Elizabeth, Pessaint, Laurent, Van Ry, Alex, Narvaez, Brandon, Valentin, Daniel, Cook, Anthony, Dodson, Alan, Steingrebe, Katelyn, Nurmukhambetova, Saule T., Godbole, Sucheta, Henry, Amy R., Laboune, Farida, Roberts-Torres, Jesmine, Lorang, Cynthia G., Amin, Shivani, Trost, Jessica, Naisan, Mursal, Basappa, Manjula, Willis, Jacquelyn, Wang, Lingshu, Shi, Wei, Doria-Rose, Nicole A., Zhang, Yi, Yang, Eun Sung, Leung, Kwanyee, O’Dell, Sijy, Schmidt, Stephen D., Olia, Adam S., Liu, Cuiping, Harris, Darcy R., Chuang, Gwo-Yu, Stewart-Jones, Guillaume, Renzi, Isabella, Lai, Yen-Ting, Malinowski, Agata, Wu, Kai, Mascola, John R., Carfi, Andrea, Kwong, Peter D., Edwards, Darin K., Lewis, Mark G., Andersen, Hanne, Corbett, Kizzmekia S., Nason, Martha C., McDermott, Adrian B., Suthar, Mehul S., Moore, Ian N., Roederer, Mario, Sullivan, Nancy J., Douek, Daniel C., Seder, Robert A.
Publicado 2022