H3K27M in Gliomas Causes a One-Step Decrease in H3K27 Methylation and Reduced Spreading within the Constraints of H3K36 Methylation

por Harutyunyan, Ashot S., Chen, Haifen, Lu, Tianyuan, Horth, Cynthia, Nikbakht, Hamid, Krug, Brian, Russo, Caterina, Bareke, Eric, Marchione, Dylan M., Coradin, Mariel, Garcia, Benjamin A., Jabado, Nada, Majewski, Jacek
Publicado 2020

KAT6A mutations in Arboleda-Tham syndrome drive epigenetic regulation of posterior HOXC cluster

por Singh, Meghna, Spendlove, Sarah, Wei, Angela, Bondhus, Leroy, Nava, Aileen, de L. Vitorino, Francisca N., Amano, Seth, Lee, Jacob, Echeverria, Gesenia, Gomez, Dianne, Garcia, Benjamin A., Arboleda, Valerie A.
Publicado 2023

Proteomic and genomic approaches reveal critical functions of H3K9 methylation and Heterochromatin Protein-1γ in reprogramming to pluripotency

por Sridharan, Rupa, Gonzales-Cope, Michelle, Chronis, Constantinos, Bonora, Giancarlo, McKee, Robin, Huang, Chengyang, Patel, Sanjeet, Lopez, David, Mishra, Nilamadhab, Pellegrini, Matteo, Carey, Michael, Garcia, Benjamin A., Plath, Kathrin
Publicado 2013

Identification of nuclear hormone receptor pathways causing insulin resistance by transcriptional and epigenomic analysis

por Kang, Sona, Tsai, Linus T., Zhou, Yiming, Evertts, Adam, Xu, Su, Griffin, Michael J., Issner, Robbyn, Whitton, Holly J., Garcia, Benjamin A., Epstein, Charles B., Mikkelsen, Tarjei S., Rosen, Evan D.
Publicado 2014

KMT2D regulates p63 target enhancers to coordinate epithelial homeostasis

por Lin-Shiao, Enrique, Lan, Yemin, Coradin, Mariel, Anderson, Amy, Donahue, Greg, Simpson, Cory L., Sen, Payel, Saffie, Rizwan, Busino, Luca, Garcia, Benjamin A., Berger, Shelley L., Capell, Brian C.
Publicado 2018

A quantitative atlas of histone modification signatures from human cancer cells

por LeRoy, Gary, DiMaggio, Peter A, Chan, Eric Y, Zee, Barry M, Blanco, M Andres, Bryant, Barbara, Flaniken, Ian Z, Liu, Sherry, Kang, Yibin, Trojer, Patrick, Garcia, Benjamin A
Publicado 2013

Memory acquisition and retrieval impact different epigenetic processes that regulate gene expression

por Peixoto, Lucia L, Wimmer, Mathieu E, Poplawski, Shane G, Tudor, Jennifer C, Kenworthy, Charles A, Liu, Shichong, Mizuno, Keiko, Garcia, Benjamin A, Zhang, Nancy R, Giese, K Peter, Abel, Ted
Publicado 2015

Histone H3K27 Dimethyl Loss is Highly Specific for Malignant Peripheral Nerve Sheath Tumor and Distinguishes True PRC2 Loss from Isolated H3K27 Trimethyl Loss

por Marchione, Dylan M, Lisby, Amanda, Viaene, Angela N, Santi, Mariarita, Nasrallah, MacLean, Wang, Li-Ping, Williams, Erik A, Larque, Ana B, Chebib, Ivan, Garcia, Benjamin A, Wojcik, John B
Publicado 2019

Automethylation of PRC2 promotes H3K27 methylation and is impaired in H3K27M pediatric glioma

por Lee, Chul-Hwan, Yu, Jia-Ray, Granat, Jeffrey, Saldaña-Meyer, Ricardo, Andrade, Joshua, LeRoy, Gary, Jin, Ying, Lund, Peder, Stafford, James M., Garcia, Benjamin A., Ueberheide, Beatrix, Reinberg, Danny
Publicado 2019

Adenovirus-mediated ubiquitination alters protein-RNA binding and aids viral RNA processing

por Herrmann, Christin, Dybas, Joseph M., Liddle, Jennifer C., Price, Alexander M, Hayer, Katharina E., Lauman, Richard, Purman, Caitlin E., Charman, Matthew, Kim, Eui Tae, Garcia, Benjamin A, Weitzman, Matthew D
Publicado 2020

The NANCI–Nkx2.1 gene duplex buffers Nkx2.1 expression to maintain lung development and homeostasis

por Herriges, Michael J., Tischfield, David J., Cui, Zheng, Morley, Michael P., Han, Yumiao, Babu, Apoorva, Li, Su, Lu, MinMin, Cendan, Isis, Garcia, Benjamin A., Anderson, Stewart A., Morrisey, Edward E.
Publicado 2017

One minute analysis of 200 histone posttranslational modifications by direct injection mass spectrometry

por Sidoli, Simone, Kori, Yekaterina, Lopes, Mariana, Yuan, Zuo-Fei, Kim, Hee Jong, Kulej, Katarzyna, Janssen, Kevin A., Agosto, Laura M., da Cunha, Julia Pinheiro Chagas, Andrews, Andrew J., Garcia, Benjamin A.
Publicado 2019

H3K36 dimethylation shapes the epigenetic interaction landscape by directing repressive chromatin modifications in embryonic stem cells

por Chen, Haifen, Hu, Bo, Horth, Cynthia, Bareke, Eric, Rosenbaum, Phillip, Kwon, Sin Young, Sirois, Jacinthe, Weinberg, Daniel N., Robison, Faith M., Garcia, Benjamin A., Lu, Chao, Pastor, William A., Majewski, Jacek
Publicado 2022

Altered chromatin occupancy of patient-associated H4 mutants misregulate neuronal differentiation

por Feng, Lijuan, Barrows, Douglas, Zhong, Liangwen, Mätlik, Kärt, Porter, Elizabeth G., Djomo, Annaelle M., Yau, Iris, Soshnev, Alexey A., Carroll, Thomas S., Wen, Duancheng, Hatten, Mary E., Garcia, Benjamin A., Allis, C. David
Publicado 2023

KAT6A mutations in Arboleda-Tham syndrome drive epigenetic regulation of posterior HOXC cluster

por Singh, Meghna, Spendlove, Sarah J., Wei, Angela, Bondhus, Leroy M., Nava, Aileen A., de L. Vitorino, Francisca N., Amano, Seth, Lee, Jacob, Echeverria, Gesenia, Gomez, Dianne, Garcia, Benjamin A., Arboleda, Valerie A.
Publicado 2023

Novel viral splicing events and open reading frames revealed by long-read direct RNA sequencing of adenovirus transcripts

por Price, Alexander M., Steinbock, Robert T., Lauman, Richard, Charman, Matthew, Hayer, Katharina E., Kumar, Namrata, Halko, Edwin, Lum, Krystal K., Wei, Monica, Wilson, Angus C., Garcia, Benjamin A., Depledge, Daniel P., Weitzman, Matthew D.
Publicado 2022

Structure and noncanonical Cdk8 activation mechanism within an Argonaute-containing Mediator kinase module

por Li, Yi-Chuan, Chao, Ti-Chun, Kim, Hee Jong, Cholko, Timothy, Chen, Shin-Fu, Li, Guojie, Snyder, Laura, Nakanishi, Kotaro, Chang, Chia-en, Murakami, Kenji, Garcia, Benjamin A., Boyer, Thomas G., Tsai, Kuang-Lei
Publicado 2021

SIRT7 links H3K18 deacetylation to maintenance of oncogenic transformation

por Barber, Matthew F., Michishita-Kioi, Eriko, Xi, Yuanxin, Tasselli, Luisa, Kioi, Mitomu, Moqtaderi, Zarmik, Tennen, Ruth I., Paredes, Silvana, Young, Nicolas L., Chen, Kaifu, Struhl, Kevin, Garcia, Benjamin A., Gozani, Or, Li, Wei, Chua, Katrin F.
Publicado 2012

The histone variant macroH2A suppresses melanoma progression through regulation of CDK8

por Kapoor, Avnish, Goldberg, Matthew S., Cumberland, Lara K., Ratnakumar, Kajan, Segura, Miguel F., Emanuel, Patrick O., Menendez, Silvia, Vardabasso, Chiara, LeRoy, Gary, Vidal, Claudia I., Polsky, David, Osman, Iman, Garcia, Benjamin A., Hernando, Eva, Bernstein, Emily
Publicado 2010

Naked Mole Rat Cells Have a Stable Epigenome that Resists iPSC Reprogramming

por Tan, Li, Ke, Zhonghe, Tombline, Gregory, Macoretta, Nicholas, Hayes, Kevin, Tian, Xiao, Lv, Ruitu, Ablaeva, Julia, Gilbert, Michael, Bhanu, Natarajan V., Yuan, Zuo-Fei, Garcia, Benjamin A., Shi, Yujiang G., Shi, Yang, Seluanov, Andrei, Gorbunova, Vera
Publicado 2017