Genetic Determinants of Serum Calcification Propensity and Cardiovascular Outcomes in the General Population

por de Haan, Amber, Ahmadizar, Fariba, van der Most, Peter J., Thio, Chris H. L., Kamali, Zoha, Ani, Alireza, Ghanbari, Mohsen, Chaker, Layal, van Meurs, Joyce, Ikram, M. Kamran, van Goor, Harry, Bakker, Stephan J. L., van der Harst, Pim, Snieder, Harold, Kavousi, Maryam, Pasch, Andreas, Eijgelsheim, Mark, de Borst, Martin H.
Publicado 2022

Complex trait methylation scores in the prediction of major depressive disorder

por Barbu, Miruna C., Amador, Carmen, Kwong, Alex S.F., Shen, Xueyi, Adams, Mark J., Howard, David M., Walker, Rosie M., Morris, Stewart W., Min, Josine L., Liu, Chunyu, van Dongen, Jenny, Ghanbari, Mohsen, Relton, Caroline, Porteous, David J., Campbell, Archie, Evans, Kathryn L., Whalley, Heather C., McIntosh, Andrew M.
Publicado 2022

Four missense genetic variants in CUBN are associated with higher levels of eGFR in non-diabetes but not in diabetes mellitus or its subtypes: A genetic association study in Europe...

por Uglebjerg, Nicoline, Ahmadizar, Fariba, Aly, Dina M., Cañadas-Garre, Marisa, Hill, Claire, Naber, Annemieke, Oddsson, Asmundur, Singh, Sunny S., Smyth, Laura, Trégouët, David-Alexandre, Chaker, Layal, Ghanbari, Mohsen, Steinthorsdottir, Valgerdur, Ahlqvist, Emma, Hadjadj, Samy, Van Hoek, Mandy, Kavousi, Maryam, McKnight, Amy Jayne, Sijbrands, Eric J., Stefansson, Kari, Simons, Matias, Rossing, Peter, Ahluwalia, Tarunveer S.
Publicado 2023

A cross-omics integrative study of metabolic signatures of chronic obstructive pulmonary disease

por Prokić, Ivana, Lahousse, Lies, de Vries, Maaike, Liu, Jun, Kalaoja, Marita, Vonk, Judith M., van der Plaat, Diana A., van Diemen, Cleo C., van der Spek, Ashley, Zhernakova, Alexandra, Fu, Jingyuan, Ghanbari, Mohsen, Ala-Korpela, Mika, Kettunen, Johannes, Havulinna, Aki S., Perola, Markus, Salomaa, Veikko, Lind, Lars, Ärnlöv, Johan, Stricker, Bruno H. C., Brusselle, Guy G., Boezen, H. Marike, van Duijn, Cornelia M., Amin, Najaf
Publicado 2020

Metabolome-wide association study on ABCA7 indicates a role of ceramide metabolism in Alzheimer’s disease

por Dehghan, Abbas, Pinto, Rui Climaco, Karaman, Ibrahim, Huang, Jian, Durainayagam, Brenan R., Ghanbari, Mohsen, Nazeer, Areesha, Zhong, Qi, Liggi, Sonia, Whiley, Luke, Mustafa, Rima, Kivipelto, Miia, Solomon, Alina, Ngandu, Tiia, Kanekiyo, Takahisa, Aikawa, Tomonori, Radulescu, Carola I., Barnes, Samuel J., Graça, Gonçalo, Chekmeneva, Elena, Camuzeaux, Stephane, Lewis, Matthew R., Kaluarachchi, Manuja R., Ikram, M. Arfan, Holmes, Elaine, Tzoulaki, Ioanna, Matthews, Paul M., Griffin, Julian L., Elliott, Paul
Publicado 2022

Validating biomarkers and models for epigenetic inference of alcohol consumption from blood

por Maas, Silvana C. E., Vidaki, Athina, Teumer, Alexander, Costeira, Ricardo, Wilson, Rory, van Dongen, Jenny, Beekman, Marian, Völker, Uwe, Grabe, Hans J., Kunze, Sonja, Ladwig, Karl-Heinz, van Meurs, Joyce B. J., Uitterlinden, André G., Voortman, Trudy, Boomsma, Dorret I., Slagboom, P. Eline, van Heemst, Diana, van der Kallen, Carla J. H., van den Berg, Leonard H., Waldenberger, Melanie, Völzke, Henry, Peters, Annette, Bell, Jordana T., Ikram, M. Arfan, Ghanbari, Mohsen, Kayser, Manfred
Publicado 2021

Metabolomic profiles predict individual multidisease outcomes

por Buergel, Thore, Steinfeldt, Jakob, Ruyoga, Greg, Pietzner, Maik, Bizzarri, Daniele, Vojinovic, Dina, Upmeier zu Belzen, Julius, Loock, Lukas, Kittner, Paul, Christmann, Lara, Hollmann, Noah, Strangalies, Henrik, Braunger, Jana M., Wild, Benjamin, Chiesa, Scott T., Spranger, Joachim, Klostermann, Fabian, van den Akker, Erik B., Trompet, Stella, Mooijaart, Simon P., Sattar, Naveed, Jukema, J. Wouter, Lavrijssen, Birgit, Kavousi, Maryam, Ghanbari, Mohsen, Ikram, Mohammad A., Slagboom, Eline, Kivimaki, Mika, Langenberg, Claudia, Deanfield, John, Eils, Roland, Landmesser, Ulf
Publicado 2022

Combined genome-wide association study of 136 quantitative ear morphology traits in multiple populations reveal 8 novel loci

por Li, Yi, Xiong, Ziyi, Zhang, Manfei, Hysi, Pirro G., Qian, Yu, Adhikari, Kaustubh, Weng, Jun, Wu, Sijie, Du, Siyuan, Gonzalez-Jose, Rolando, Schuler-Faccini, Lavinia, Bortolini, Maria-Catira, Acuna-Alonzo, Victor, Canizales-Quinteros, Samuel, Gallo, Carla, Poletti, Giovanni, Bedoya, Gabriel, Rothhammer, Francisco, Wang, Jiucun, Tan, Jingze, Yuan, Ziyu, Jin, Li, Uitterlinden, André G., Ghanbari, Mohsen, Ikram, M. Arfan, Nijsten, Tamar, Zhu, Xiangyu, Lei, Zhen, Jia, Peilin, Ruiz-Linares, Andres, Spector, Timothy D., Wang, Sijia, Kayser, Manfred, Liu, Fan
Publicado 2023

Validated inference of smoking habits from blood with a finite DNA methylation marker set

por Maas, Silvana C. E., Vidaki, Athina, Wilson, Rory, Teumer, Alexander, Liu, Fan, van Meurs, Joyce B. J., Uitterlinden, André G., Boomsma, Dorret I., de Geus, Eco J. C., Willemsen, Gonneke, van Dongen, Jenny, van der Kallen, Carla J. H., Slagboom, P. Eline, Beekman, Marian, van Heemst, Diana, van den Berg, Leonard H., Duijts, Liesbeth, Jaddoe, Vincent W. V., Ladwig, Karl-Heinz, Kunze, Sonja, Peters, Annette, Ikram, M. Arfan, Grabe, Hans J., Felix, Janine F., Waldenberger, Melanie, Franco, Oscar H., Ghanbari, Mohsen, Kayser, Manfred
Publicado 2019

DNA repair in cardiomyocytes is critical for maintaining cardiac function in mice

por de Boer, Martine, te Lintel Hekkert, Maaike, Chang, Jiang, van Thiel, Bibi S., Martens, Leonie, Bos, Maxime M., de Kleijnen, Marion G. J., Ridwan, Yanto, Octavia, Yanti, van Deel, Elza D., Blonden, Lau A., Brandt, Renata M. C., Barnhoorn, Sander, Bautista‐Niño, Paula K., Krabbendam‐Peters, Ilona, Wolswinkel, Rianne, Arshi, Banafsheh, Ghanbari, Mohsen, Kupatt, Christian, de Windt, Leon J., Danser, A. H. Jan, van der Pluijm, Ingrid, Remme, Carol Ann, Stoll, Monika, Pothof, Joris, Roks, Anton J. M., Kavousi, Maryam, Essers, Jeroen, van der Velden, Jolanda, Hoeijmakers, Jan H. J., Duncker, Dirk J.
Publicado 2023

Bivariate genome-wide association meta-analysis of pediatric musculoskeletal traits reveals pleiotropic effects at the SREBF1/TOM1L2 locus

por Medina-Gomez, Carolina, Kemp, John P., Dimou, Niki L., Kreiner, Eskil, Chesi, Alessandra, Zemel, Babette S., Bønnelykke, Klaus, Boer, Cindy G., Ahluwalia, Tarunveer S., Bisgaard, Hans, Evangelou, Evangelos, Heppe, Denise H. M., Bonewald, Lynda F., Gorski, Jeffrey P., Ghanbari, Mohsen, Demissie, Serkalem, Duque, Gustavo, Maurano, Matthew T., Kiel, Douglas P., Hsu, Yi-Hsiang, C.J. van der Eerden, Bram, Ackert-Bicknell, Cheryl, Reppe, Sjur, Gautvik, Kaare M., Raastad, Truls, Karasik, David, van de Peppel, Jeroen, Jaddoe, Vincent W. V., Uitterlinden, André G., Tobias, Jonathan H., Grant, Struan F.A., Bagos, Pantelis G., Evans, David M., Rivadeneira, Fernando
Publicado 2017

A metabolic profile of all-cause mortality risk identified in an observational study of 44,168 individuals

por Deelen, Joris, Kettunen, Johannes, Fischer, Krista, van der Spek, Ashley, Trompet, Stella, Kastenmüller, Gabi, Boyd, Andy, Zierer, Jonas, van den Akker, Erik B., Ala-Korpela, Mika, Amin, Najaf, Demirkan, Ayse, Ghanbari, Mohsen, van Heemst, Diana, Ikram, M. Arfan, van Klinken, Jan Bert, Mooijaart, Simon P., Peters, Annette, Salomaa, Veikko, Sattar, Naveed, Spector, Tim D., Tiemeier, Henning, Verhoeven, Aswin, Waldenberger, Melanie, Würtz, Peter, Davey Smith, George, Metspalu, Andres, Perola, Markus, Menni, Cristina, Geleijnse, Johanna M., Drenos, Fotios, Beekman, Marian, Jukema, J. Wouter, van Duijn, Cornelia M., Slagboom, P. Eline
Publicado 2019

Genetic analysis in European ancestry individuals identifies 517 loci associated with liver enzymes

por Pazoki, Raha, Vujkovic, Marijana, Elliott, Joshua, Evangelou, Evangelos, Gill, Dipender, Ghanbari, Mohsen, van der Most, Peter J., Pinto, Rui Climaco, Wielscher, Matthias, Farlik, Matthias, Zuber, Verena, de Knegt, Robert J., Snieder, Harold, Uitterlinden, André G., Lynch, Julie A., Jiang, Xiyun, Said, Saredo, Kaplan, David E., Lee, Kyung Min, Serper, Marina, Carr, Rotonya M., Tsao, Philip S., Atkinson, Stephen R., Dehghan, Abbas, Tzoulaki, Ioanna, Ikram, M. Arfan, Herzig, Karl-Heinz, Järvelin, Marjo-Riitta, Alizadeh, Behrooz Z., O’Donnell, Christopher J., Saleheen, Danish, Voight, Benjamin F., Chang, Kyong-Mi, Thursz, Mark R., Elliott, Paul
Publicado 2021

Meta-analysis of genome-wide association studies identifies ancestry-specific associations underlying circulating total tau levels

por Sarnowski, Chloé, Ghanbari, Mohsen, Bis, Joshua C., Logue, Mark, Fornage, Myriam, Mishra, Aniket, Ahmad, Shahzad, Beiser, Alexa S., Boerwinkle, Eric, Bouteloup, Vincent, Chouraki, Vincent, Cupples, L Adrienne, Damotte, Vincent, DeCarli, Charles S., DeStefano, Anita L., Djoussé, Luc, Fohner, Alison E., Franz, Carol E., Kautz, Tiffany F., Lambert, Jean-Charles, Lyons, Michael J., Mosley, Thomas H., Mukamal, Kenneth J., Pase, Matthew P., Portilla Fernandez, Eliana C., Rissman, Robert A., Satizabal, Claudia L., Vasan, Ramachandran S., Yaqub, Amber, Debette, Stephanie, Dufouil, Carole, Launer, Lenore J., Kremen, William S., Longstreth, William T., Ikram, M Arfan, Seshadri, Sudha
Publicado 2022

Meta-analysis of epigenome-wide association studies of carotid intima-media thickness

por Portilla-Fernández, Eliana, Hwang, Shih-Jen, Wilson, Rory, Maddock, Jane, Hill, W. David, Teumer, Alexander, Mishra, Pashupati P., Brody, Jennifer A., Joehanes, Roby, Ligthart, Symen, Ghanbari, Mohsen, Kavousi, Maryam, Roks, Anton J. M., Danser, A. H. Jan, Levy, Daniel, Peters, Annette, Ghasemi, Sahar, Schminke, Ulf, Dörr, Marcus, Grabe, Hans J., Lehtimäki, Terho, Kähönen, Mika, Hurme, Mikko A., Bartz, Traci M., Sotoodehnia, Nona, Bis, Joshua C., Thiery, Joachim, Koenig, Wolfgang, Ong, Ken K., Bell, Jordana T., Meisinger, Christine, Wardlaw, Joanna M., Starr, John M., Seissler, Jochen, Then, Cornelia, Rathmann, Wolfgang, Ikram, M. Arfan, Psaty, Bruce M., Raitakari, Olli T., Völzke, Henry, Deary, Ian J., Wong, Andrew, Waldenberger, Melanie, O’Donnell, Christopher J., Dehghan, Abbas
Publicado 2021

Higher thyrotropin leads to unfavorable lipid profile and somewhat higher cardiovascular disease risk: evidence from multi-cohort Mendelian randomization and metabolomic profiling

por van Vliet, Nicolien A., Bos, Maxime M., Thesing, Carisha S., Chaker, Layal, Pietzner, Maik, Houtman, Evelyn, Neville, Matt J., Li-Gao, Ruifang, Trompet, Stella, Mustafa, Rima, Ahmadizar, Fariba, Beekman, Marian, Bot, Mariska, Budde, Kathrin, Christodoulides, Constantinos, Dehghan, Abbas, Delles, Christian, Elliott, Paul, Evangelou, Marina, Gao, He, Ghanbari, Mohsen, van Herwaarden, Antonius E., Ikram, M. Arfan, Jaeger, Martin, Jukema, J. Wouter, Karaman, Ibrahim, Karpe, Fredrik, Kloppenburg, Margreet, Meessen, Jennifer M. T. A., Meulenbelt, Ingrid, Milaneschi, Yuri, Mooijaart, Simon P., Mook-Kanamori, Dennis O., Netea, Mihai G., Netea-Maier, Romana T., Peeters, Robin P., Penninx, Brenda W. J. H., Sattar, Naveed, Slagboom, P. Eline, Suchiman, H. Eka D., Völzke, Henry, Willems van Dijk, Ko, Noordam, Raymond, van Heemst, Diana
Publicado 2021

Genetic and clinical determinants of abdominal aortic diameter: genome-wide association studies, exome array data and Mendelian randomization study

por Portilla-Fernandez, Eliana, Klarin, Derek, Hwang, Shih-Jen, Biggs, Mary L, Bis, Joshua C, Weiss, Stefan, Rospleszcz, Susanne, Natarajan, Pradeep, Hoffmann, Udo, Rogers, Ian S, Truong, Quynh A, Völker, Uwe, Dörr, Marcus, Bülow, Robin, Criqui, Michael H, Allison, Matthew, Ganesh, Santhi K, Yao, Jie, Waldenberger, Melanie, Bamberg, Fabian, Rice, Kenneth M, Essers, Jeroen, Kapteijn, Daniek M C, van der Laan, Sander W, de Knegt, Rob J, Ghanbari, Mohsen, Felix, Janine F, Ikram, M Arfan, Kavousi, Maryam, Uitterlinden, Andre G, Roks, Anton J M, Danser, A H Jan, Tsao, Philip S, Damrauer, Scott M, Guo, Xiuqing, Rotter, Jerome I, Psaty, Bruce M, Kathiresan, Sekar, Völzke, Henry, Peters, Annette, Johnson, Craig, Strauch, Konstantin, Meitinger, Thomas, O’Donnell, Christopher J, Dehghan, Abbas
Publicado 2022

Genomic analysis of diet composition finds novel loci and associations with health and lifestyle

por Meddens, S. Fleur W., de Vlaming, Ronald, Bowers, Peter, Burik, Casper A. P., Linnér, Richard Karlsson, Lee, Chanwook, Okbay, Aysu, Turley, Patrick, Rietveld, Cornelius A., Fontana, Mark Alan, Ghanbari, Mohsen, Imamura, Fumiaki, McMahon, George, van der Most, Peter J., Voortman, Trudy, Wade, Kaitlin H., Anderson, Emma L., Braun, Kim V. E., Emmett, Pauline M., Esko, Tonũ, Gonzalez, Juan R., Kiefte-de Jong, Jessica C., Langenberg, Claudia, Luan, Jian’an, Muka, Taulant, Ring, Susan, Rivadeneira, Fernando, Snieder, Harold, van Rooij, Frank J. A., Wolffenbuttel, Bruce H. R., Smith, George Davey, Franco, Oscar H., Forouhi, Nita G., Ikram, M. Arfan, Uitterlinden, Andre G., van Vliet-Ostaptchouk, Jana V., Wareham, Nick J., Cesarini, David, Harden, K. Paige, Lee, James J., Benjamin, Daniel J., Chow, Carson C., Koellinger, Philipp D.
Publicado 2020

Epigenome-wide association meta-analysis of DNA methylation with coffee and tea consumption

por Karabegović, Irma, Portilla-Fernandez, Eliana, Li, Yang, Ma, Jiantao, Maas, Silvana C. E., Sun, Daokun, Hu, Emily A., Kühnel, Brigitte, Zhang, Yan, Ambatipudi, Srikant, Fiorito, Giovanni, Huang, Jian, Castillo-Fernandez, Juan E., Wiggins, Kerri L., de Klein, Niek, Grioni, Sara, Swenson, Brenton R., Polidoro, Silvia, Treur, Jorien L., Cuenin, Cyrille, Tsai, Pei-Chien, Costeira, Ricardo, Chajes, Veronique, Braun, Kim, Verweij, Niek, Kretschmer, Anja, Franke, Lude, van Meurs, Joyce B. J., Uitterlinden, André G., de Knegt, Robert J., Ikram, M. Arfan, Dehghan, Abbas, Peters, Annette, Schöttker, Ben, Gharib, Sina A., Sotoodehnia, Nona, Bell, Jordana T., Elliott, Paul, Vineis, Paolo, Relton, Caroline, Herceg, Zdenko, Brenner, Hermann, Waldenberger, Melanie, Rebholz, Casey M., Voortman, Trudy, Pan, Qiuwei, Fornage, Myriam, Levy, Daniel, Kayser, Manfred, Ghanbari, Mohsen
Publicado 2021

Investigating the relationships between unfavourable habitual sleep and metabolomic traits: evidence from multi-cohort multivariable regression and Mendelian randomization analyses

por Bos, Maxime M., Goulding, Neil J., Lee, Matthew A., Hofman, Amy, Bot, Mariska, Pool, René, Vijfhuizen, Lisanne S., Zhang, Xiang, Li, Chihua, Mustafa, Rima, Neville, Matt J., Li-Gao, Ruifang, Trompet, Stella, Beekman, Marian, Biermasz, Nienke R., Boomsma, Dorret I., de Boer, Irene, Christodoulides, Constantinos, Dehghan, Abbas, van Dijk, Ko Willems, Ford, Ian, Ghanbari, Mohsen, Heijmans, Bastiaan T., Ikram, M. Arfan, Jukema, J. Wouter, Mook-Kanamori, Dennis O., Karpe, Fredrik, Luik, Annemarie I., Lumey, L. H., van den Maagdenberg, Arn M. J. M., Mooijaart, Simon P., de Mutsert, Renée, Penninx, Brenda W. J. H., Rensen, Patrick C. N., Richmond, Rebecca C., Rosendaal, Frits R., Sattar, Naveed, Schoevers, Robert A., Slagboom, P. Eline, Terwindt, Gisela M., Thesing, Carisha S., Wade, Kaitlin H., Wijsman, Carolien A., Willemsen, Gonneke, Zwinderman, Aeilko H., van Heemst, Diana, Noordam, Raymond, Lawlor, Deborah A.
Publicado 2021