Gut bacteria from multiple sclerosis patients modulate human T cells and exacerbate symptoms in mouse models

por Cekanaviciute, Egle, Yoo, Bryan B., Runia, Tessel F., Debelius, Justine W., Singh, Sneha, Nelson, Charlotte A., Kanner, Rachel, Bencosme, Yadira, Lee, Yun Kyung, Hauser, Stephen L., Crabtree-Hartman, Elizabeth, Sand, Ilana Katz, Gacias, Mar, Zhu, Yunjiao, Casaccia, Patrizia, Cree, Bruce A. C., Knight, Rob, Mazmanian, Sarkis K., Baranzini, Sergio E.
Publicado 2017

A specific amino acid motif of HLA-DRB1 mediates risk and interacts with smoking history in Parkinson’s disease

por Hollenbach, Jill A., Norman, Paul J., Creary, Lisa E., Damotte, Vincent, Montero-Martin, Gonzalo, Caillier, Stacy, Anderson, Kirsten M., Misra, Maneesh K., Nemat-Gorgani, Neda, Osoegawa, Kazutoyo, Santaniello, Adam, Renschen, Adam, Marin, Wesley M., Dandekar, Ravi, Parham, Peter, Tanner, Caroline M., Hauser, Stephen L., Fernandez-Viña, Marcelo, Oksenberg, Jorge R.
Publicado 2019

Remote Observational Research for Multiple Sclerosis: A Natural Experiment

por Bove, Riley, Poole, Shane, Cuneo, Richard, Gupta, Sasha, Sabatino, Joseph, Harms, Meagan, Cooper, Tifffany, Rowles, William, Miller, Nicolette, Gomez, Refujia, Lincoln, Robin, McPolin, Kira, Powers, Kyra, Santaniello, Adam, Renschen, Adam, Bevan, Carolyn J., Gelfand, Jeffrey M., Goodin, Douglas S., Guo, Chu-Yueh, Romeo, Andrew R., Hauser, Stephen L., Campbell Cree, Bruce Anthony
Publicado 2022

A Major Histocompatibility Class I Locus Contributes to Multiple Sclerosis Susceptibility Independently from HLA-DRB1*15:01

por Cree, Bruce A. C., Rioux, John D., McCauley, Jacob L., Gourraud, Pierre-Antoine F. D., Goyette, Philippe, McElroy, Joseph, De Jager, Philip, Santaniello, Adam, Vyse, Timothy J., Gregersen, Peter K., Mirel, Daniel, Hafler, David A., Haines, Jonathan L., Pericak-Vance, Margaret A., Compston, Alastair, Sawcer, Stephen J., Oksenberg, Jorge R., Hauser, Stephen L.
Publicado 2010

Evidence of novel fine-scale structural variation at autism spectrum disorder candidate loci

por Hedges, Dale J, Hamilton-Nelson, Kara L, Sacharow, Stephanie J, Nations, Laura, Beecham, Gary W, Kozhekbaeva, Zhanna M, Butler, Brittany L, Cukier, Holly N, Whitehead, Patrice L, Ma, Deqiong, Jaworski, James M, Nathanson, Lubov, Lee, Joycelyn M, Hauser, Stephen L, Oksenberg, Jorge R, Cuccaro, Michael L, Haines, Jonathan L, Gilbert, John R, Pericak-Vance, Margaret A
Publicado 2012

Risk of requiring a wheelchair in primary progressive multiple sclerosis: Data from the ORATORIO trial and the MSBase registry

por Butzkueven, Helmut, Spelman, Tim, Horakova, Dana, Hughes, Stella, Solaro, Claudio, Izquierdo, Guillermo, Kubala Havrdová, Eva, Grand'Maison, Francois, Prat, Alexandre, Girard, Marc, Hupperts, Raymond, Onofrj, Marco, Lugaresi, Alessandra, Taylor, Bruce, Giovannoni, Gavin, Kappos, Ludwig, Hauser, Stephen L., Montalban, Xavier, Craveiro, Licinio, Freitas, Rita, Model, Fabian, Overell, James, Muros‐Le Rouzic, Erwan, Sauter, Annette, Wang, Qing, Wormser, David, Wolinsky, Jerry S.
Publicado 2021

A non-synonymous SNP within membrane metalloendopeptidase-like 1 (MMEL1) is associated with multiple sclerosis

por Ban, Maria, McCauley, Jacob L., Zuvich, Rebecca, Baker, Amie, Bergamaschi, Laura, Cox, Mathew, Kemppinen, Anu, D’Alfonso, Sandra, Guerini, Franca R., Lechner-Scott, Jeannette, Dudbridge, Frank, Wason, James, Robertson, Neil P., De Jager, Philip L., Hafler, David A., Barcellos, Lisa F., Ivinson, Adrian J., Sexton, David, Oksenberg, Jorge R., Hauser, Stephen L., Pericak-Vance, Margaret A., Haines, Jonathan, Compston, Alastair, Sawcer, Stephen
Publicado 2010

High density mapping of the MHC identifies a shared role for HLA-DRB1*01:03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis

por Goyette, Philippe, Boucher, Gabrielle, Mallon, Dermot, Ellinghaus, Eva, Jostins, Luke, Huang, Hailiang, Ripke, Stephan, Gusareva, Elena S, Annese, Vito, Hauser, Stephen L, Oksenberg, Jorge R, Thomsen, Ingo, Leslie, Stephen, Daly, Mark J, Van Steen, Kristel, Duerr, Richard H, Barrett, Jeffrey C, McGovern, Dermot PB, Schumm, L Philip, Traherne, James A, Carrington, Mary N, Kosmoliaptsis, Vasilis, Karlsen, Tom H, Franke, Andre, Rioux, John D
Publicado 2015

A pathogenic and clonally expanded B cell transcriptome in active multiple sclerosis

por Ramesh, Akshaya, Schubert, Ryan D., Greenfield, Ariele L., Dandekar, Ravi, Loudermilk, Rita, Sabatino, Joseph J., Koelzer, Matthew T., Tran, Edwina B., Koshal, Kanishka, Kim, Kicheol, Pröbstel, Anne-Katrin, Banerji, Debarko, Guo, Chu-Yueh, Green, Ari J., Bove, Riley M., DeRisi, Joseph L., Gelfand, Jeffrey M., Cree, Bruce A. C., Zamvil, Scott S., Baranzini, Sergio E., Hauser, Stephen L., Wilson, Michael R.
Publicado 2020

A second major histocompatibility complex susceptibility locus for multiple sclerosis

por Yeo, Tai Wai, De Jager, Philip L, Gregory, Simon G, Barcellos, Lisa F, Walton, Amie, Goris, An, Fenoglio, Chiara, Ban, Maria, Taylor, Craig J, Goodman, Reyna S, Walsh, Emily, Wolfish, Cara S, Horton, Roger, Traherne, James, Beck, Stephan, Trowsdale, John, Caillier, Stacy J, Ivinson, Adrian J, Green, Todd, Pobywajlo, Susan, Lander, Eric S, Pericak-Vance, Margaret A, Haines, Jonathan L, Daly, Mark J, Oksenberg, Jorge R, Hauser, Stephen L, Compston, Alastair, Hafler, David A, Rioux, John D, Sawcer, Stephen
Publicado 2007

Meta-analysis of genome-wide association studies reveals genetic overlap between Hodgkin lymphoma and multiple sclerosis

por Khankhanian, Pouya, Cozen, Wendy, Himmelstein, Daniel S, Madireddy, Lohith, Din, Lennox, van den Berg, Anke, Matsushita, Takuya, Glaser, Sally L, Moré, Jayaji M, Smedby, Karin E., Baranzini, Sergio E, Mack, Thomas M, Lizée, Antoine, de Sanjosé, Silvia, Gourraud, Pierre-Antoine, Nieters, Alexandra, Hauser, Stephen L, Cocco, Pierluigi, Maynadié, Marc, Foretová, Lenka, Staines, Anthony, Delahaye-Sourdeix, Manon, Li, Dalin, Bhatia, Smita, Melbye, Mads, Onel, Kenan, Jarrett, Ruth, McKay, James D, Oksenberg, Jorge R, Hjalgrim, Henrik
Publicado 2016

Silent progression in disease activity–free relapsing multiple sclerosis

por Cree, Bruce A. C., Hollenbach, Jill A., Bove, Riley, Kirkish, Gina, Sacco, Simone, Caverzasi, Eduardo, Bischof, Antje, Gundel, Tristan, Zhu, Alyssa H., Papinutto, Nico, Stern, William A., Bevan, Carolyn, Romeo, Andrew, Goodin, Douglas S., Gelfand, Jeffrey M., Graves, Jennifer, Green, Ari J., Wilson, Michael R., Zamvil, Scott S., Zhao, Chao, Gomez, Refujia, Ragan, Nicholas R., Rush, Gillian Q., Barba, Patrick, Santaniello, Adam, Baranzini, Sergio E., Oksenberg, Jorge R., Henry, Roland G., Hauser, Stephen L.
Publicado 2019

Comprehensive follow-up of the first genome-wide association study of multiple sclerosis identifies KIF21B and TMEM39A as susceptibility loci

por McCauley, Jacob L., Zuvich, Rebecca L., Beecham, Ashley H., De Jager, Philip L., Konidari, Ioanna, Whitehead, Patrice L., Aubin, Cristin, Ban, Maria, Pobywajlo, Susan, Briskin, Rebeccah, Romano, Susan, Aggarwal, Neelum T., Piccio, Laura, McArdle, Wendy L., Strachan, David P., Evans, Denis, Cross, Anne H., Cree, Bruce, Rioux, John D., Barcellos, Lisa F., Ivinson, Adrian J., Compston, Alastair, Hafler, David A., Hauser, Stephen L., Oksenberg, Jorge R., Sawcer, Stephen J., Pericak-Vance, Margaret A., Haines, Jonathan L.
Publicado 2010

Genome, epigenome and RNA sequences of monozygotic twins discordant for multiple sclerosis

por Baranzini, Sergio E., Mudge, Joann, van Velkinburgh, Jennifer C., Khankhanian, Pouya, Khrebtukova, Irina, Miller, Neil A., Zhang, Lu, Farmer, Andrew D., Bell, Callum J., Kim, Ryan W., May, Gregory D., Woodward, Jimmy E., Caillier, Stacy J., McElroy, Joseph P., Gomez, Refujia, Pando, Marcelo J., Clendenen, Leonda E., Ganusova, Elena E., Schilkey, Faye D., Ramaraj, Thiruvarangan, Khan, Omar A., Huntley, Jim J., Luo, Shujun, Kwok, Pui-yan, Wu, Thomas D., Schroth, Gary P., Oksenberg, Jorge R., Hauser, Stephen L., Kingsmore, Stephen F.
Publicado 2010

Long‐term evolution of multiple sclerosis disability in the treatment era

por Cree, Bruce A. C., Gourraud, Pierre‐Antoine, Oksenberg, Jorge R., Bevan, Carolyn, Crabtree‐Hartman, Elizabeth, Gelfand, Jeffrey M., Goodin, Douglas S., Graves, Jennifer, Green, Ari J., Mowry, Ellen, Okuda, Darin T., Pelletier, Daniel, von Büdingen, H.‐Christian, Zamvil, Scott S., Agrawal, Alisha, Caillier, Stacy, Ciocca, Caroline, Gomez, Refujia, Kanner, Rachel, Lincoln, Robin, Lizee, Antoine, Qualley, Pamela, Santaniello, Adam, Suleiman, Leena, Bucci, Monica, Panara, Valentina, Papinutto, Nico, Stern, William A., Zhu, Alyssa H., Cutter, Gary R., Baranzini, Sergio, Henry, Roland G., Hauser, Stephen L.
Publicado 2016

Spinal Cord Atrophy Predicts Progressive Disease in Relapsing Multiple Sclerosis

por Bischof, Antje, Papinutto, Nico, Keshavan, Anisha, Rajesh, Anand, Kirkish, Gina, Zhang, Xinheng, Mallott, Jacob M., Asteggiano, Carlo, Sacco, Simone, Gundel, Tristan J., Zhao, Chao, Stern, William A., Caverzasi, Eduardo, Zhou, Yifan, Gomez, Refujia, Ragan, Nicholas R., Santaniello, Adam, Zhu, Alyssa H., Juwono, Jeremy, Bevan, Carolyn J., Bove, Riley M., Crabtree, Elizabeth, Gelfand, Jeffrey M., Goodin, Douglas S., Graves, Jennifer S., Green, Ari J., Oksenberg, Jorge R., Waubant, Emmanuelle, Wilson, Michael R., Zamvil, Scott S., Cree, Bruce A. C., Hauser, Stephen L., Henry, Roland G.
Publicado 2022

Reply to “Spinal Cord Atrophy Is a Preclinical Marker of Progressive MS”

por Bischof, Antje, Papinutto, Nico, Keshavan, Anisha, Rajesh, Anand, Kirkish, Gina, Zhang, Xinheng, Mallott, Jacob M., Asteggiano, Carlo, Sacco, Simone, Gundel, Tristan J., Zhao, Chao, Stern, William A., Caverzasi, Eduardo, Zhou, Yifan, Gomez, Refujia, Ragan, Nicholas R., Santaniello, Adam, Zhu, Alyssa H., Juwono, Jeremy, Bevan, Carolyn J., Bove, Riley M., Crabtree‐Hartman, Elizabeth, Gelfand, Jeffrey M., Goodin, Douglas S., Graves, Jennifer S., Green, Ari J., Oksenberg, Jorge R., Waubant, Emmanuelle, Wilson, Michael R., Zamvil, Scott S., Cree, Bruce A., Hauser, Stephen L., Henry, Roland G.
Publicado 2022

Multiple sclerosis risk loci and disease severity in 7,125 individuals from 10 studies

por George, Michaela F., Briggs, Farren B.S., Shao, Xiaorong, Gianfrancesco, Milena A., Kockum, Ingrid, Harbo, Hanne F., Celius, Elisabeth G., Bos, Steffan D., Hedström, Anna, Shen, Ling, Bernstein, Allan, Alfredsson, Lars, Hillert, Jan, Olsson, Tomas, Patsopoulos, Nikolaos A., De Jager, Philip L., Oturai, Annette B., Søndergaard, Helle B., Sellebjerg, Finn, Sorensen, Per S., Gomez, Refujia, Caillier, Stacy J., Cree, Bruce A.C., Oksenberg, Jorge R., Hauser, Stephen L., D'Alfonso, Sandra, Leone, Maurizio A., Boneschi, Filippo Martinelli, Sorosina, Melissa, van der Mei, Ingrid, Taylor, Bruce V., Zhou, Yuan, Schaefer, Catherine, Barcellos, Lisa F.
Publicado 2016

A Predictive Autoantibody Signature in Multiple Sclerosis

por Zamecnik, Colin R., Sowa, Gavin M., Abdelhak, Ahmed, Dandekar, Ravi, Bair, Rebecca D., Wade, Kristen J., Bartley, Christopher M., Tubati, Asritha, Gomez, Refujia, Fouassier, Camille, Gerungan, Chloe, Alexander, Jessica, Wapniarski, Anne E., Loudermilk, Rita P., Eggers, Erica L., Zorn, Kelsey C., Ananth, Kirtana, Jabassini, Nora, Mann, Sabrina A., Ragan, Nicholas R., Santaniello, Adam, Henry, Roland G., Baranzini, Sergio E., Zamvil, Scott S., Bove, Riley M., Guo, Chu-Yueh, Gelfand, Jeffrey M., Cuneo, Richard, von Büdingen, H.-Christian, Oksenberg, Jorge R., Cree, Bruce AC, Hollenbach, Jill A., Green, Ari J., Hauser, Stephen L., Wallin, Mitchell T., DeRisi, Joseph L., Wilson, Michael R.
Publicado 2023

KIR(+)CD8(+) T cells suppress pathogenic T cells and are active in autoimmune diseases and COVID-19

por Li, Jing, Zaslavsky, Maxim, Su, Yapeng, Guo, Jing, Sikora, Michael J., van Unen, Vincent, Christophersen, Asbjørn, Chiou, Shin-Heng, Chen, Liang, Li, Jiefu, Ji, Xuhuai, Wilhelmy, Julie, McSween, Alana M., Palanski, Brad A., Mallajosyula, Venkata Vamsee Aditya, Bracey, Nathan A., Dhondalay, Gopal Krishna R., Bhamidipati, Kartik, Pai, Joy, Kipp, Lucas B., Dunn, Jeffrey E., Hauser, Stephen L., Oksenberg, Jorge R., Satpathy, Ansuman T., Robinson, William H., Dekker, Cornelia L., Steinmetz, Lars M., Khosla, Chaitan, Utz, Paul J., Sollid, Ludvig M., Chien, Yueh-Hsiu, Heath, James R., Fernandez-Becker, Nielsen Q., Nadeau, Kari C., Saligrama, Naresha, Davis, Mark M.
Publicado 2022