Neurofilament-Light, a Promising Biomarker: Analytical, Metrological and Clinical Challenges

por Coppens, Salomé, Lehmann, Sylvain, Hopley, Christopher, Hirtz, Christophe
Publicado 2023

Readthrough isoform of aquaporin-4 (AQP4) as a therapeutic target for Alzheimer’s disease and other proteinopathies

por Mohaupt, Pablo, Vialaret, Jérôme, Hirtz, Christophe, Lehmann, Sylvain
Publicado 2023

Editorial: Proteomics as a Tool for Biomarker and Drug Target Discovery: Improving the Diagnosis and Treatment of Neurodegenerative Diseases

por Belbin, Olivia, Lehmann, Sylvain, Sabidó, Eduard, Hirtz, Christophe
Publicado 2020

From radioimmunoassay to mass spectrometry: a new method to quantify orexin-A (hypocretin-1) in cerebrospinal fluid

por Hirtz, Christophe, Vialaret, Jérôme, Gabelle, Audrey, Nowak, Nora, Dauvilliers, Yves, Lehmann, Sylvain
Publicado 2016

The alternative proteome in neurobiology

por Mohaupt, Pablo, Roucou, Xavier, Delaby, Constance, Vialaret, Jérôme, Lehmann, Sylvain, Hirtz, Christophe
Publicado 2022

Proteomics Challenges for the Assessment of Synuclein Proteoforms as Clinical Biomarkers in Parkinson’s Disease

por Pons, Marie-Laure, Loftus, Neil, Vialaret, Jerome, Moreau, Stephane, Lehmann, Sylvain, Hirtz, Christophe
Publicado 2022

β-Synuclein as a candidate blood biomarker for synaptic degeneration in Alzheimer’s disease

por Mohaupt, Pablo, Pons, Marie-Laure, Vialaret, Jérôme, Delaby, Constance, Hirtz, Christophe, Lehmann, Sylvain
Publicado 2022

Antibody-free quantification of seven tau peptides in human CSF using targeted mass spectrometry

por Bros, Pauline, Vialaret, Jérôme, Barthelemy, Nicolas, Delatour, Vincent, Gabelle, Audrey, Lehmann, Sylvain, Hirtz, Christophe
Publicado 2015

Sample Pooling and Inflammation Linked to the False Selection of Biomarkers for Neurodegenerative Diseases in Top–Down Proteomics: A Pilot Study

por Molinari, Nicolas, Roche, Stéphane, Peoc’h, Katell, Tiers, Laurent, Séveno, Martial, Hirtz, Christophe, Lehmann, Sylvain
Publicado 2018

Peripheral Blood and Salivary Biomarkers of Blood–Brain Barrier Permeability and Neuronal Damage: Clinical and Applied Concepts

por Janigro, Damir, Bailey, Damian M., Lehmann, Sylvain, Badaut, Jerome, O'Flynn, Robin, Hirtz, Christophe, Marchi, Nicola
Publicado 2021

Changes Occurring on the Activity of Salivary Alpha-Amylase Proteoforms in Two Naturalistic Situations Using a Spectrophotometric Assay

por Contreras-Aguilar, María D., Mateo, Sandra V., Tecles, Fernando, Hirtz, Christophe, Escribano, Damián, Cerón, Jose J.
Publicado 2021

Cerebrospinal fluid phospho-tau T217 outperforms T181 as a biomarker for the differential diagnosis of Alzheimer’s disease and PET amyloid-positive patient identification

por Barthélemy, Nicolas R., Bateman, Randall J., Hirtz, Christophe, Marin, Philippe, Becher, François, Sato, Chihiro, Gabelle, Audrey, Lehmann, Sylvain
Publicado 2020

Excreted/Secreted Proteins from Trypanosome Procyclic Strains

por Atyame Nten, Celestine Michelle, Sommerer, Nicolas, Rofidal, Valerie, Hirtz, Christophe, Rossignol, Michel, Cuny, Gerard, Peltier, Jean-Benoit, Geiger, Anne
Publicado 2010

Exocytosis and protein secretion in Trypanosoma

por Geiger, Anne, Hirtz, Christophe, Bécue, Thierry, Bellard, Eric, Centeno, Delphine, Gargani, Daniel, Rossignol, Michel, Cuny, Gérard, Peltier, Jean-Benoit
Publicado 2010

Repeated neurofilament light chain measurements did not capture Riluzole therapeutic effect in amyotrophic lateral sclerosis patients

por Esselin, Florence, De la Cruz, Elisa, Hirtz, Christophe, Tiers, Laurent, Alphandery, Sébastien, Baudesson, Léandra, Taieb, Guillaume, Camu, William, Lehmann, Sylvain
Publicado 2022

Identification of multiple proteoforms biomarkers on clinical samples by routine Top-Down approaches

por Vialaret, Jerome, Schmit, Pierre-Olivier, Lehmann, Sylvain, Gabelle, Audrey, Wood, Jason, Bern, Marshall, Paape, Rainer, Suckau, Detlev, Kruppa, Gary, Hirtz, Christophe
Publicado 2018

Hepcidin and ferritin levels in restless legs syndrome: a case–control study

por Chenini, Sofiene, Delaby, Constance, Rassu, Anna-Laura, Barateau, Lucie, Vialaret, Jérôme, Hirtz, Christophe, Dupuy, Anne Marie, Lehmann, Sylvain, Jaussent, Isabelle, Dauvilliers, Yves
Publicado 2020

The prognostic value of the Tau protein serum level in metastatic breast cancer patients and its correlation with brain metastases

por Darlix, Amélie, Hirtz, Christophe, Thezenas, Simon, Maceski, Aleksandra, Gabelle, Audrey, Lopez-Crapez, Evelyne, De Forges, Hélène, Firmin, Nelly, Guiu, Séverine, Jacot, William, Lehmann, Sylvain
Publicado 2019

Bystander effectors of chondrosarcoma cells irradiated at different LET impair proliferation of chondrocytes

por Lepleux, Charlotte, Marie-Brasset, Aurélie, Temelie, Mihaela, Boulanger, Marion, Brotin, Émilie, Goldring, Mary B., Hirtz, Christophe, Varès, Guillaume, Nakajima, Tetsuo, Saintigny, Yannick, Savu, Diana, Chevalier, François
Publicado 2019

Blood amyloid and tau biomarkers as predictors of cerebrospinal fluid profiles

por Delaby, Constance, Alcolea, Daniel, Hirtz, Christophe, Vialaret, Jérôme, Kindermans, Jana, Morichon, Lisa, Fortea, Juan, Belbin, Olivia, Gabelle, Audrey, Blennow, Kaj, Zetterberg, Henrik, Lleó, Alberto, Lehmann, Sylvain
Publicado 2022