HACE1 blocks HIF1α accumulation under hypoxia in a RAC1 dependent manner

por Turgu, Busra, Zhang, Fan, El-Naggar, Amal, Negri, Gian Luca, Kogler, Melanie, Tortola, Luigi, Johnson, Fraser, Ng, Tony, Li, Amy, Yapp, Donald, Lockwood, William, Martinez, Daniel, Maris, John M., Daugaard, Mads, Penninger, Josef M., Hughes, Christopher S., Sorensen, Poul H.
Publicado 2021

Cerebellar associative sensory learning defects in five mouse autism models

por Kloth, Alexander D, Badura, Aleksandra, Li, Amy, Cherskov, Adriana, Connolly, Sara G, Giovannucci, Andrea, Bangash, M Ali, Grasselli, Giorgio, Peñagarikano, Olga, Piochon, Claire, Tsai, Peter T, Geschwind, Daniel H, Hansel, Christian, Sahin, Mustafa, Takumi, Toru, Worley, Paul F, Wang, Samuel S-H
Publicado 2015

Models of cardiovascular surgery biobanking to facilitate translational research and precision medicine

por Zhu, YingYan, Jackson, Dan, Hunter, Benjamin, Beattie, Lorna, Turner, Lisa, Hambly, Brett D., Jeremy, Richmond W., Malecki, Cassandra, Robertson, Elizabeth N., Li, Amy, dos Remedios, Cris, Richmond, David, Semsarian, Christopher, O'Sullivan, John F., Bannon, Paul G., Lal, Sean
Publicado 2021

Abnormal contractility in human heart myofibrils from patients with dilated cardiomyopathy due to mutations in TTN and contractile protein genes

por Vikhorev, Petr G., Smoktunowicz, Natalia, Munster, Alex B., Copeland, O’Neal, Kostin, Sawa, Montgiraud, Cecile, Messer, Andrew E., Toliat, Mohammad R., Li, Amy, dos Remedios, Cristobal G., Lal, Sean, Blair, Cheavar A., Campbell, Kenneth S., Guglin, Maya, Richter, Manfred, Knöll, Ralph, Marston, Steven B.
Publicado 2017

The impact of rare variation on gene expression across tissues

por Li, Xin, Kim, Yungil, Tsang, Emily K., Davis, Joe R., Damani, Farhan N., Chiang, Colby, Hess, Gaelen T., Zappala, Zachary, Strober, Benjamin J., Scott, Alexandra J., Li, Amy, Ganna, Andrea, Bassik, Michael C., Merker, Jason D., Hall, Ira M., Battle, Alexis, Montgomery, Stephen B.
Publicado 2017

Author Correction: Abnormal contractility in human heart myofibrils from patients with dilated cardiomyopathy due to mutations in TTN and contractile protein genes

por Vikhorev, Petr G., Smoktunowicz, Natalia, Munster, Alex B., Copeland, O’ Neal, Kostin, Sawa, Montgiraud, Cecile, Messer, Andrew E., Toliat, Mohammad R., Li, Amy, dos Remedios, Cristobal G., Lal, Sean, Blair, Cheavar A., Campbell, Kenneth S., Guglin, Maya, Richter, Manfred, Knöll, Ralph, Marston, Steven B.
Publicado 2018

Prolonged Impairment of Short-Chain Fatty Acid and L-Isoleucine Biosynthesis in Gut Microbiome in Patients With COVID-19

por Zhang, Fen, Wan, Yating, Zuo, Tao, Yeoh, Yun Kit, Liu, Qin, Zhang, Lin, Zhan, Hui, Lu, Wenqi, Xu, Wenye, Lui, Grace C.Y., Li, Amy Y.L., Cheung, Chun Pan, Wong, Chun Kwok, Chan, Paul K.S., Chan, Francis K.L., Ng, Siew C.
Publicado 2022

Gut microbiota composition is associated with SARS-CoV-2 vaccine immunogenicity and adverse events

por Ng, Siew C, Peng, Ye, Zhang, Lin, Mok, Chris KP, Zhao, Shilin, Li, Amy, Ching, Jessica YL, Liu, Yingzhi, Yan, Shuai, Chan, Dream L S, Zhu, Jie, Chen, Chunke, Fung, Adrian CH, Wong, Kenneth KY, Hui, David SC, Chan, Francis KL, Tun, Hein M
Publicado 2022

Delayed and Attenuated Antibody Responses to Coronavirus Disease 2019 Vaccination With Poor Cross-Variant Neutralization in Solid-Organ Transplant Recipients—A Prospective Longitud...

por Liew, May Y, Mathews, Josh I, Li, Amy, Singh, Rohan, Jaramillo, Salvador A, Weiss, Zoe F, Bowman, Kathryn, Ankomah, Pierre O, Ghantous, Fadi, Lewis, Gregory D, Neuringer, Isabel, Bitar, Natasha, Lipiner, Taryn, Dighe, Anand S, Kotton, Camille N, Seaman, Michael S, Lemieux, Jacob E, Goldberg, Marcia B
Publicado 2023

Antibiotics and probiotics impact gut antimicrobial resistance gene reservoir in COVID-19 patients

por Su, Qi, Liu, Qin, Zhang, Lin, Xu, Zhilu, Liu, Chenyu, Lu, Wenqi, Ching, Jessica YL, Li, Amy, Mak, Joyce Wing Yan, Lui, Grace Chung Yan, Ng, Susanna So Shan, Chow, Kai Ming, Hui, David SC, Chan, Paul KS, Chan, Francis Ka Leung, Ng, Siew C
Publicado 2022

Targeted genomic CRISPR-Cas9 screen identifies MAP4K4 as essential for glioblastoma invasion

por Prolo, Laura M., Li, Amy, Owen, Scott F., Parker, Jonathon J., Foshay, Kara, Nitta, Ryan T., Morgens, David W., Bolin, Sara, Wilson, Christy M., Vega L, Johana C. M., Luo, Emily J., Nwagbo, Gigi, Waziri, Allen, Li, Gordon, Reimer, Richard J., Bassik, Michael C., Grant, Gerald A.
Publicado 2019

Multi-kingdom gut microbiota analyses define COVID-19 severity and post-acute COVID-19 syndrome

por Liu, Qin, Su, Qi, Zhang, Fen, Tun, Hein M., Mak, Joyce Wing Yan, Lui, Grace Chung-Yan, Ng, Susanna So Shan, Ching, Jessica Y. L., Li, Amy, Lu, Wenqi, Liu, Chenyu, Cheung, Chun Pan, Hui, David S. C., Chan, Paul K. S., Chan, Francis Ka Leung, Ng, Siew C.
Publicado 2022

Bithionol blocks pathogenicity of bacterial toxins, ricin, and Zika virus

por Leonardi, William, Zilbermintz, Leeor, Cheng, Luisa W., Zozaya, Josue, Tran, Sharon H., Elliott, Jeffrey H., Polukhina, Kseniya, Manasherob, Robert, Li, Amy, Chi, Xiaoli, Gharaibeh, Dima, Kenny, Tara, Zamani, Rouzbeh, Soloveva, Veronica, Haddow, Andrew D., Nasar, Farooq, Bavari, Sina, Bassik, Michael C., Cohen, Stanley N., Levitin, Anastasia, Martchenko, Mikhail
Publicado 2016

Retro-2 protects cells from ricin toxicity by inhibiting ASNA1-mediated ER targeting and insertion of tail-anchored proteins

por Morgens, David W, Chan, Charlene, Kane, Andrew J, Weir, Nicholas R, Li, Amy, Dubreuil, Michael M, Tsui, C Kimberly, Hess, Gaelen T, Lavertu, Adam, Han, Kyuho, Polyakov, Nicole, Zhou, Jing, Handy, Emma L, Alabi, Philip, Dombroski, Amanda, Yao, David, Altman, Russ B, Sello, Jason K, Denic, Vladimir, Bassik, Michael C
Publicado 2019

Mitigation of off-target toxicity in CRISPR-Cas9 screens for essential non-coding elements

por Tycko, Josh, Wainberg, Michael, Marinov, Georgi K., Ursu, Oana, Hess, Gaelen T., Ego, Braeden K., Aradhana, Li, Amy, Truong, Alisa, Trevino, Alexandro E., Spees, Kaitlyn, Yao, David, Kaplow, Irene M., Greenside, Peyton G., Morgens, David W., Phanstiel, Douglas H., Snyder, Michael P., Bintu, Lacramioara, Greenleaf, William J., Kundaje, Anshul, Bassik, Michael C.
Publicado 2019

Distinct hypertrophic cardiomyopathy genotypes result in convergent sarcomeric proteoform profiles revealed by top-down proteomics

por Tucholski, Trisha, Cai, Wenxuan, Gregorich, Zachery R., Bayne, Elizabeth F., Mitchell, Stanford D., McIlwain, Sean J., de Lange, Willem J., Wrobbel, Max, Karp, Hannah, Hite, Zachary, Vikhorev, Petr G., Marston, Steven B., Lal, Sean, Li, Amy, dos Remedios, Cristobal, Kohmoto, Takushi, Hermsen, Joshua, Ralphe, J. Carter, Kamp, Timothy J., Moss, Richard L., Ge, Ying
Publicado 2020

Alterations in Gut Microbiota of Patients With COVID-19 During Time of Hospitalization

por Zuo, Tao, Zhang, Fen, Lui, Grace C.Y., Yeoh, Yun Kit, Li, Amy Y.L., Zhan, Hui, Wan, Yating, Chung, Arthur C.K., Cheung, Chun Pan, Chen, Nan, Lai, Christopher K.C., Chen, Zigui, Tso, Eugene Y.K., Fung, Kitty S.C., Chan, Veronica, Ling, Lowell, Joynt, Gavin, Hui, David S.C., Chan, Francis K.L., Chan, Paul K.S., Ng, Siew C.
Publicado 2020

CRISPR screens in cancer spheroids identify 3D growth specific vulnerabilities

por Han, Kyuho, Pierce, Sarah E., Li, Amy, Spees, Kaitlyn, Anderson, Gray R., Seoane, Jose A., Lo, Yuan-Hung, Dubreuil, Michael, Olivas, Micah, Kamber, Roarke A., Wainberg, Michael, Kostyrko, Kaja, Kelly, Marcus R., Yousefi, Maryam, Simpkins, Scott W., Yao, David, Lee, Keonil, Kuo, Calvin J., Jackson, Peter K., Sweet-Cordero, Alejandro, Kundaje, Anshul, Gentles, Andrew J., Curtis, Christina, Winslow, Monte M., Bassik, Michael C.
Publicado 2020

Temporal landscape of human gut RNA and DNA virome in SARS-CoV-2 infection and severity

por Zuo, Tao, Liu, Qin, Zhang, Fen, Yeoh, Yun Kit, Wan, Yating, Zhan, Hui, Lui, Grace C. Y., Chen, Zigui, Li, Amy Y. L., Cheung, Chun Pan, Chen, Nan, Lv, Wenqi, Ng, Rita W. Y., Tso, Eugene Y. K., Fung, Kitty S. C., Chan, Veronica, Ling, Lowell, Joynt, Gavin, Hui, David S. C., Chan, Francis K. L., Chan, Paul K. S., Ng, Siew C.
Publicado 2021

Gut microbiota composition reflects disease severity and dysfunctional immune responses in patients with COVID-19

por Yeoh, Yun Kit, Zuo, Tao, Lui, Grace Chung-Yan, Zhang, Fen, Liu, Qin, Li, Amy YL, Chung, Arthur CK, Cheung, Chun Pan, Tso, Eugene YK, Fung, Kitty SC, Chan, Veronica, Ling, Lowell, Joynt, Gavin, Hui, David Shu-Cheong, Chow, Kai Ming, Ng, Susanna So Shan, Li, Timothy Chun-Man, Ng, Rita WY, Yip, Terry CF, Wong, Grace Lai-Hung, Chan, Francis KL, Wong, Chun Kwok, Chan, Paul KS, Ng, Siew C
Publicado 2021