Longitudinal findings of a U.S. preventive evidence-based family intervention tested among youth in Ecuador: Familias Unidas

por Estrada, Yannine, Lozano, Alyssa, Terán, Ana M. Quevedo, Eckembrecher, Daphne G., Rojas, Lourdes M., Tamayo, Cecilia Condo, Lee, Tae Kyoung, Velázquez, María Rosa, Tapia, María I., Martin, Julio, Prado, Guillermo
Publicado 2023

Complex Interplay between Sphingolipid and Sterol Metabolism Revealed by Perturbations to the Leishmania Metabolome Caused by Miltefosine

por Armitage, Emily G., Alqaisi, Amjed Q. I., Godzien, Joanna, Peña, Imanol, Mbekeani, Alison J., Alonso-Herranz, Vanesa, López-Gonzálvez, Ángeles, Martín, Julio, Gabarro, Raquel, Denny, Paul W., Barrett, Michael P., Barbas, Coral
Publicado 2018

Identifying inhibitors of the Leishmania inositol phosphorylceramide synthase with antiprotozoal activity using a yeast-based assay and ultra-high throughput screening platform

por Norcliffe, Jennifer L., Mina, John G., Alvarez, Emilio, Cantizani, Juan, de Dios-Anton, Francisco, Colmenarejo, Gonzalo, Valle, Silva Gonzalez-Del, Marco, Maria, Fiandor, José M., Martin, Julio J., Steel, Patrick G., Denny, Paul W.
Publicado 2018

Multiple unbiased approaches identify oxidosqualene cyclase as the molecular target of a promising anti-leishmanial

por Paradela, Luciana S., Wall, Richard J., Carvalho, Sandra, Chemi, Giulia, Corpas-Lopez, Victoriano, Moynihan, Eoin, Bello, Davide, Patterson, Stephen, Güther, Maria Lucia S., Fairlamb, Alan H., Ferguson, Michael A.J., Zuccotto, Fabio, Martin, Julio, Gilbert, Ian H., Wyllie, Susan
Publicado 2021

Genomic and Phenotypic Characterization of Experimentally Selected Resistant Leishmania donovani Reveals a Role for Dynamin-1-Like Protein in the Mechanism of Resistance to a Novel...

por Hefnawy, Aya, Negreira, Gabriel, Jara, Marlene, Cotton, James A., Maes, Ilse, D’Haenens, Erika, Imamura, Hideo, Cuypers, Bart, Monsieurs, Pieter, Mouchtoglou, Christina, De Winter, Hans, Pintelon, Isabel, Timmermans, Jean-Pierre, Berriman, Matt, Sanders, Mandy, Martin, Julio, de Muylder, Geraldine, Dujardin, Jean-Claude, Sterckx, Yann G.-J., Domagalska, Malgorzata Anna
Publicado 2022

The Q(i) Site of Cytochrome b is a Promiscuous Drug Target in Trypanosoma cruzi and Leishmania donovani

por Wall, Richard J., Carvalho, Sandra, Milne, Rachel, Bueren-Calabuig, Juan A., Moniz, Sonia, Cantizani-Perez, Juan, MacLean, Lorna, Kessler, Albane, Cotillo, Ignacio, Sastry, Lalitha, Manthri, Sujatha, Patterson, Stephen, Zuccotto, Fabio, Thompson, Stephen, Martin, Julio, Marco, Maria, Miles, Timothy J., De Rycker, Manu, Thomas, Michael G., Fairlamb, Alan H., Gilbert, Ian H., Wyllie, Susan
Publicado 2020

Scaffold-Hopping Strategy on a Series of Proteasome Inhibitors Led to a Preclinical Candidate for the Treatment of Visceral Leishmaniasis

por Thomas, Michael, Brand, Stephen, De Rycker, Manu, Zuccotto, Fabio, Lukac, Iva, Dodd, Peter G., Ko, Eun-Jung, Manthri, Sujatha, McGonagle, Kate, Osuna-Cabello, Maria, Riley, Jennifer, Pont, Caterina, Simeons, Frederick, Stojanovski, Laste, Thomas, John, Thompson, Stephen, Viayna, Elisabet, Fiandor, Jose M., Martin, Julio, Wyatt, Paul G., Miles, Timothy J., Read, Kevin D., Marco, Maria, Gilbert, Ian H.
Publicado 2021

Tocilizumab in visual involvement of giant cell arteritis: a multicenter study of 471 patients

por Loricera, Javier, Castañeda, Santos, Moriano, Clara, Narváez, Javier, Aldasoro, Vicente, Maiz, Olga, Melero, Rafael, Villa, Ignacio, Vela, Paloma, Romero-Yuste, Susana, Callejas, José L., de Miguel, Eugenio, Galíndez-Agirregoikoa, Eva, Sivera, Francisca, Fernández-López, Jesús C., Galisteo, Carles, Ferraz-Amaro, Iván, Sánchez-Martín, Julio, Sánchez-Bilbao, Lara, Calderón-Goercke, Mónica, Casado, Alfonso, Hernández, José L., González-Gay, Miguel A., Blanco, Ricardo
Publicado 2022

Structure-Guided Design and Synthesis of a Pyridazinone Series of Trypanosoma cruzi Proteasome Inhibitors

por Thomas, Michael G., McGonagle, Kate, Rowland, Paul, Robinson, David A., Dodd, Peter G., Camino-Díaz, Isabel, Campbell, Lorna, Cantizani, Juan, Castañeda, Pablo, Conn, Daniel, Craggs, Peter D., Edwards, Darren, Ferguson, Liam, Fosberry, Andrew, Frame, Laura, Goswami, Panchali, Hu, Xiao, Korczynska, Justyna, MacLean, Lorna, Martin, Julio, Mutter, Nicole, Osuna-Cabello, Maria, Paterson, Christy, Peña, Imanol, Pinto, Erika G., Pont, Caterina, Riley, Jennifer, Shishikura, Yoko, Simeons, Frederick R. C., Stojanovski, Laste, Thomas, John, Wrobel, Karolina, Young, Robert J., Zmuda, Filip, Zuccotto, Fabio, Read, Kevin D., Gilbert, Ian H., Marco, Maria, Miles, Timothy J., Manzano, Pilar, De Rycker, Manu
Publicado 2023

Preclinical candidate for the treatment of visceral leishmaniasis that acts through proteasome inhibition

por Wyllie, Susan, Brand, Stephen, Thomas, Michael, De Rycker, Manu, Chung, Chun-wa, Pena, Imanol, Bingham, Ryan P., Bueren-Calabuig, Juan A., Cantizani, Juan, Cebrian, David, Craggs, Peter D., Ferguson, Liam, Goswami, Panchali, Hobrath, Judith, Howe, Jonathan, Jeacock, Laura, Ko, Eun-Jung, Korczynska, Justyna, MacLean, Lorna, Manthri, Sujatha, Martinez, Maria S., Mata-Cantero, Lydia, Moniz, Sonia, Nühs, Andrea, Osuna-Cabello, Maria, Pinto, Erika, Riley, Jennifer, Robinson, Sharon, Rowland, Paul, Simeons, Frederick R. C., Shishikura, Yoko, Spinks, Daniel, Stojanovski, Laste, Thomas, John, Thompson, Stephen, Viayna Gaza, Elisabet, Wall, Richard J., Zuccotto, Fabio, Horn, David, Ferguson, Michael A. J., Fairlamb, Alan H., Fiandor, Jose M., Martin, Julio, Gray, David W., Miles, Timothy J., Gilbert, Ian H., Read, Kevin D., Marco, Maria, Wyatt, Paul G.
Publicado 2019