High-Throughput CRISPR Screening Identifies Genes Involved in Macrophage Viability and Inflammatory Pathways

por Covarrubias, Sergio, Cortez Vollmers, Apple, Capili, Allyson, Boettcher, Michael, Shulkin, Aaron, Correa, Michele Ramos, Halasz, Haley, Robinson, Elektra K., O’Briain, Laura, Vollmers, Christopher, Blau, James, Katzman, Sol, McManus, Michael T., Carpenter, Susan
Publicado 2020

Macrophage Exosomes Resolve Atherosclerosis by Regulating Hematopoiesis and Inflammation via MicroRNA Cargo

por Bouchareychas, Laura, Duong, Phat, Covarrubias, Sergio, Alsop, Eric, Phu, Tuan Anh, Chung, Allen, Gomes, Michael, Wong, David, Meechoovet, Bessie, Capili, Allyson, Yamamoto, Ryo, Nakauchi, Hiromitsu, McManus, Michael T., Carpenter, Susan, Van Keuren-Jensen, Kendall, Raffai, Robert L.
Publicado 2020

Genomic Resolution of DLX-Orchestrated Transcriptional Circuits Driving Development of Forebrain GABAergic Neurons

por Lindtner, Susan, Catta-Preta, Rinaldo, Tian, Hua, Su-Feher, Linda, Price, James D., Dickel, Diane E., Greiner, Vanille, Silberberg, Shanni N., McKinsey, Gabriel L., McManus, Michael T., Pennacchio, Len A., Visel, Axel, Nord, Alex S., Rubenstein, John L.R.
Publicado 2019

miR-200 deficiency promotes lung cancer metastasis by activating Notch signaling in cancer-associated fibroblasts

por Xue, Bin, Chuang, Chen-Hua, Prosser, Haydn M., Fuziwara, Cesar Seigi, Chan, Claudia, Sahasrabudhe, Neil, Kühn, Maximilian, Wu, Yalei, Chen, Jingqi, Biton, Anne, Chen, Caifu, Wilkinson, John Erby, McManus, Michael T., Bradley, Allan, Winslow, Monte M., Su, Bo, He, Lin
Publicado 2021

Host–Receptor Post-Translational Modifications Refine Staphylococcal Leukocidin Cytotoxicity

por Tromp, Angelino T., Van Gent, Michiel, Jansen, Joris P., Scheepmaker, Lisette M., Velthuizen, Anneroos, De Haas, Carla J.C., Van Kessel, Kok P.M., Bardoel, Bart W., Boettcher, Michael, McManus, Michael T., Van Strijp, Jos A.G., Lebbink, Robert Jan, Haas, Pieter-Jan A., Spaan, András N.
Publicado 2020

A high-coverage shRNA screen identifies TMEM129 as an E3 ligase involved in ER-associated protein degradation

por van de Weijer, Michael L., Bassik, Michael C., Luteijn, Rutger D., Voorburg, Cornelia M., Lohuis, Mirjam A.M., Kremmer, Elisabeth, Hoeben, Rob C., LeProust, Emily M., Chen, Siyuan, Hoelen, Hanneke, Ressing, Maaike E., Patena, Weronika, Weissman, Jonathan S., McManus, Michael T., Wiertz, Emmanuel J.H.J., Lebbink, Robert Jan
Publicado 2014

Biogenesis, delivery, and function of extracellular RNA

por Patton, James G., Franklin, Jeffrey L., Weaver, Alissa M., Vickers, Kasey, Zhang, Bing, Coffey, Robert J., Ansel, K. Mark, Blelloch, Robert, Goga, Andrei, Huang, Bo, L'Etoille, Noelle, Raffai, Robert L., Lai, Charles P., Krichevsky, Anna M., Mateescu, Bogdan, Greiner, Vanille J., Hunter, Craig, Voinnet, Olivier, McManus, Michael T.
Publicado 2015

miR-15/16 Restrain Memory T Cell Differentiation, Cell Cycle, and Survival

por Gagnon, John D., Kageyama, Robin, Shehata, Hesham M., Fassett, Marlys S., Mar, Darryl J., Wigton, Eric J., Johansson, Kristina, Litterman, Adam J., Odorizzi, Pamela, Simeonov, Dimitre, Laidlaw, Brian J., Panduro, Marisella, Patel, Sana, Jeker, Lukas T., Feeney, Margaret E., McManus, Michael T., Marson, Alexander, Matloubian, Mehrdad, Sanjabi, Shomyseh, Ansel, K. Mark
Publicado 2019

BCAA catabolism in brown fat controls energy homeostasis through SLC25A44

por Yoneshiro, Takeshi, Wang, Qiang, Tajima, Kazuki, Matsushita, Mami, Maki, Hiroko, Igarashi, Kaori, Dai, Zhipeng, White, Phillip J., McGarrah, Robert W., Ilkayeva, Olga R, Deleye, Yann, Oguri, Yasuo, Kuroda, Mito, Ikeda, Kenji, Li, Huixia, Ueno, Ayano, Ohishi, Maki, Ishikawa, Takamasa, Kim, Kyeongkyu, Chen, Yong, Sponton, Carlos Henrique, Pradhan, Rachana N., Majd, Homa, Greiner, Vanille Juliette, Yoneshiro, Momoko, Brown, Zachary, Chondronikola, Maria, Takahashi, Haruya, Goto, Tsuyoshi, Kawada, Teruo, Sidossis, Labros, Szoka, Francis C., McManus, Michael T., Saito, Masayuki, Soga, Tomoyoshi, Kajimura, Shingo
Publicado 2019

Epigenetic and transcriptional determinants of the human breast

por Gascard, Philippe, Bilenky, Misha, Sigaroudinia, Mahvash, Zhao, Jianxin, Li, Luolan, Carles, Annaick, Delaney, Allen, Tam, Angela, Kamoh, Baljit, Cho, Stephanie, Griffith, Malachi, Chu, Andy, Robertson, Gordon, Cheung, Dorothy, Li, Irene, Heravi-Moussavi, Alireza, Moksa, Michelle, Mingay, Matthew, Hussainkhel, Angela, Davis, Brad, Nagarajan, Raman P., Hong, Chibo, Echipare, Lorigail, O’Geen, Henriette, Hangauer, Matthew J., Cheng, Jeffrey B., Neel, Dana, Hu, Donglei, McManus, Michael T., Moore, Richard, Mungall, Andrew, Ma, Yussanne, Plettner, Patrick, Ziv, Elad, Wang, Ting, Farnham, Peggy J., Jones, Steven J.M., Marra, Marco A., Tlsty, Thea D., Costello, Joseph F., Hirst, Martin
Publicado 2015

Integrative analysis of 111 reference human epigenomes

por Kundaje, Anshul, Meuleman, Wouter, Ernst, Jason, Bilenky, Misha, Yen, Angela, Kheradpour, Pouya, Zhang, Zhizhuo, Heravi-Moussavi, Alireza, Liu, Yaping, Amin, Viren, Ziller, Michael J, Whitaker, John W, Schultz, Matthew D, Sandstrom, Richard S, Eaton, Matthew L, Wu, Yi-Chieh, Wang, Jianrong, Ward, Lucas D, Sarkar, Abhishek, Quon, Gerald, Pfenning, Andreas, Wang, Xinchen, Claussnitzer, Melina, Coarfa, Cristian, Harris, R Alan, Shoresh, Noam, Epstein, Charles B, Gjoneska, Elizabeta, Leung, Danny, Xie, Wei, Hawkins, R David, Lister, Ryan, Hong, Chibo, Gascard, Philippe, Mungall, Andrew J, Moore, Richard, Chuah, Eric, Tam, Angela, Canfield, Theresa K, Hansen, R Scott, Kaul, Rajinder, Sabo, Peter J, Bansal, Mukul S, Carles, Annaick, Dixon, Jesse R, Farh, Kai-How, Feizi, Soheil, Karlic, Rosa, Kim, Ah-Ram, Kulkarni, Ashwinikumar, Li, Daofeng, Lowdon, Rebecca, Mercer, Tim R, Neph, Shane J, Onuchic, Vitor, Polak, Paz, Rajagopal, Nisha, Ray, Pradipta, Sallari, Richard C, Siebenthall, Kyle T, Sinnott-Armstrong, Nicholas, Stevens, Michael, Thurman, Robert E, Wu, Jie, Zhang, Bo, Zhou, Xin, Beaudet, Arthur E, Boyer, Laurie A, De Jager, Philip, Farnham, Peggy J, Fisher, Susan J, Haussler, David, Jones, Steven, Li, Wei, Marra, Marco, McManus, Michael T, Sunyaev, Shamil, Thomson, James A, Tlsty, Thea D, Tsai, Li-Huei, Wang, Wei, Waterland, Robert A, Zhang, Michael, Chadwick, Lisa H, Bernstein, Bradley E, Costello, Joseph F, Ecker, Joseph R, Hirst, Martin, Meissner, Alexander, Milosavljevic, Aleksandar, Ren, Bing, Stamatoyannopoulos, John A, Wang, Ting, Kellis, Manolis
Publicado 2015