Small molecule inhibitors and CRISPR/Cas9 mutagenesis demonstrate that SMYD2 and SMYD3 activity are dispensable for autonomous cancer cell proliferation

por Thomenius, Michael J., Totman, Jennifer, Harvey, Darren, Mitchell, Lorna H., Riera, Thomas V., Cosmopoulos, Kat, Grassian, Alexandra R., Klaus, Christine, Foley, Megan, Admirand, Elizabeth A., Jahic, Haris, Majer, Christina, Wigle, Tim, Jacques, Suzanne L., Gureasko, Jodi, Brach, Dorothy, Lingaraj, Trupti, West, Kip, Smith, Sherri, Rioux, Nathalie, Waters, Nigel J., Tang, Cuyue, Raimondi, Alejandra, Munchhof, Michael, Mills, James E., Ribich, Scott, Porter Scott, Margaret, Kuntz, Kevin W., Janzen, William P., Moyer, Mikel, Smith, Jesse J., Chesworth, Richard, Copeland, Robert A., Boriack-Sjodin, P. Ann
Publicado 2018

Topological Data Analysis as a Morphometric Method: Using Persistent Homology to Demarcate a Leaf Morphospace

por Li, Mao, An, Hong, Angelovici, Ruthie, Bagaza, Clement, Batushansky, Albert, Clark, Lynn, Coneva, Viktoriya, Donoghue, Michael J., Edwards, Erika, Fajardo, Diego, Fang, Hui, Frank, Margaret H., Gallaher, Timothy, Gebken, Sarah, Hill, Theresa, Jansky, Shelley, Kaur, Baljinder, Klahs, Phillip C., Klein, Laura L., Kuraparthy, Vasu, Londo, Jason, Migicovsky, Zoë, Miller, Allison, Mohn, Rebekah, Myles, Sean, Otoni, Wagner C., Pires, J. C., Rieffer, Edmond, Schmerler, Sam, Spriggs, Elizabeth, Topp, Christopher N., Van Deynze, Allen, Zhang, Kuang, Zhu, Linglong, Zink, Braden M., Chitwood, Daniel H.
Publicado 2018

Life-threatening influenza pneumonitis in a child with inherited IRF9 deficiency

por Hernandez, Nicholas, Melki, Isabelle, Jing, Huie, Habib, Tanwir, Huang, Susie S.Y., Danielson, Jeffrey, Kula, Tomasz, Drutman, Scott, Belkaya, Serkan, Rattina, Vimel, Lorenzo-Diaz, Lazaro, Boulai, Anais, Rose, Yoann, Kitabayashi, Naoki, Rodero, Mathieu P., Dumaine, Cecile, Blanche, Stéphane, Lebras, Marie-Noëlle, Leung, Man Chun, Mathew, Lisa Sara, Boisson, Bertrand, Zhang, Shen-Ying, Boisson-Dupuis, Stephanie, Giliani, Silvia, Chaussabel, Damien, Notarangelo, Luigi D., Elledge, Stephen J., Ciancanelli, Michael J., Abel, Laurent, Zhang, Qian, Marr, Nico, Crow, Yanick J., Su, Helen C., Casanova, Jean-Laurent
Publicado 2018

BMP9-induced osteoblastic differentiation requires functional Notch signaling in mesenchymal stem cells

por Cui, Jing, Zhang, Wenwen, Huang, Enyi, Wang, Jia, Liao, Junyi, Li, Ruidong, Yu, Xinyi, Zhao, Chen, Zeng, Zongyue, Shu, Yi, Zhang, Ruyi, Yan, Shujuan, Lei, Jiayan, Yang, Chao, Wu, Ke, Wu, Ying, Huang, Shifeng, Ji, Xiaojuan, Li, Alexander, Gong, Cheng, Yuan, Chengfu, Zhang, Linghuan, Liu, Wei, Huang, Bo, Feng, Yixiao, An, Liping, Zhang, Bo, Dai, Zhengyu, Shen, Yi, Luo, Wenping, Wang, Xi, Huang, Ailong, Luu, Hue H., Reid, Russell R., Wolf, Jennifer Moriatis, Thinakaran, Gopal, Lee, Michael J., He, Tong-Chuan
Publicado 2018

Pathologic gene network rewiring implicates PPP1R3A as a central regulator in pressure overload heart failure

por Cordero, Pablo, Parikh, Victoria N., Chin, Elizabeth T., Erbilgin, Ayca, Gloudemans, Michael J., Shang, Ching, Huang, Yong, Chang, Alex C., Smith, Kevin S., Dewey, Frederick, Zaleta, Kathia, Morley, Michael, Brandimarto, Jeff, Glazer, Nicole, Waggott, Daryl, Pavlovic, Aleksandra, Zhao, Mingming, Moravec, Christine S., Tang, W. H. Wilson, Skreen, Jamie, Malloy, Christine, Hannenhalli, Sridhar, Li, Hongzhe, Ritter, Scott, Li, Mingyao, Bernstein, Daniel, Connolly, Andrew, Hakonarson, Hakon, Lusis, Aldons J., Margulies, Kenneth B., Depaoli-Roach, Anna A., Montgomery, Stephen B., Wheeler, Matthew T., Cappola, Thomas, Ashley, Euan A.
Publicado 2019

BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design

por Farnaby, William, Koegl, Manfred, Roy, Michael J., Whitworth, Claire, Diers, Emelyne, Trainor, Nicole, Zollman, David, Steurer, Steffen, Karolyi-Oezguer, Jale, Riedmueller, Carina, Gmaschitz, Teresa, Wachter, Johannes, Dank, Christian, Galant, Michael, Sharps, Bernadette, Rumpel, Klaus, Traxler, Elisabeth, Gerstberger, Thomas, Schnitzer, Renate, Petermann, Oliver, Greb, Peter, Weinstabl, Harald, Bader, Gerd, Zoephel, Andreas, Weiss-Puxbaum, Alexander, Ehrenhöfer-Wölfer, Katharina, Wöhrle, Simon, Boehmelt, Guido, Rinnenthal, Joerg, Arnhof, Heribert, Wiechens, Nicola, Wu, Meng-Ying, Owen-Hughes, Tom, Ettmayer, Peter, Pearson, Mark, McConnell, Darryl B., Ciulli, Alessio
Publicado 2019

Establishing an infrastructure for collaboration in primate cognition research

por Altschul, Drew M., Beran, Michael J., Bohn, Manuel, Call, Josep, DeTroy, Sarah, Duguid, Shona J., Egelkamp, Crystal L., Fichtel, Claudia, Fischer, Julia, Flessert, Molly, Hanus, Daniel, Haun, Daniel B. M., Haux, Lou M., Hernandez-Aguilar, R. Adriana, Herrmann, Esther, Hopper, Lydia M., Joly, Marine, Kano, Fumihiro, Keupp, Stefanie, Melis, Alicia P., Motes Rodrigo, Alba, Ross, Stephen R., Sánchez-Amaro, Alejandro, Sato, Yutaro, Schmitt, Vanessa, Schweinfurth, Manon K., Seed, Amanda M., Taylor, Derry, Völter, Christoph J., Warren, Elizabeth, Watzek, Julia
Publicado 2019

Epidemiology of Covid-19 in a Long-Term Care Facility in King County, Washington

por McMichael, Temet M., Currie, Dustin W., Clark, Shauna, Pogosjans, Sargis, Kay, Meagan, Schwartz, Noah G., Lewis, James, Baer, Atar, Kawakami, Vance, Lukoff, Margaret D., Ferro, Jessica, Brostrom-Smith, Claire, Rea, Thomas D., Sayre, Michael R., Riedo, Francis X., Russell, Denny, Hiatt, Brian, Montgomery, Patricia, Rao, Agam K., Chow, Eric J., Tobolowsky, Farrell, Hughes, Michael J., Bardossy, Ana C., Oakley, Lisa P., Jacobs, Jesica R., Stone, Nimalie D., Reddy, Sujan C., Jernigan, John A., Honein, Margaret A., Clark, Thomas A., Duchin, Jeffrey S.
Publicado 2020

Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model

por Rogers, Thomas F., Zhao, Fangzhu, Huang, Deli, Beutler, Nathan, Burns, Alison, He, Wan-ting, Limbo, Oliver, Smith, Chloe, Song, Ge, Woehl, Jordan, Yang, Linlin, Abbott, Robert K., Callaghan, Sean, Garcia, Elijah, Hurtado, Jonathan, Parren, Mara, Peng, Linghang, Ramirez, Sydney, Ricketts, James, Ricciardi, Michael J., Rawlings, Stephen A., Wu, Nicholas C., Yuan, Meng, Smith, Davey M., Nemazee, David, Teijaro, John R., Voss, James E., Wilson, Ian A., Andrabi, Raiees, Briney, Bryan, Landais, Elise, Sok, Devin, Jardine, Joseph G., Burton, Dennis R.
Publicado 2020

Longitudinal follow-up after telephone disclosure in the randomized COGENT Study

por Kilbride, Madison K., Egleston, Brian L., Hall, Michael J., Patrick-Miller, Linda J., Daly, Mary B., Ganschow, Pamela, Grana, Generosa, Olopade, Olufunmilayo I., Fetzer, Dominique, Brandt, Amanda, Chambers, Rachelle, Clark, Dana F., Forman, Andrea, Gaber, Rikki, Gulden, Cassandra, Horte, Janice, Long, Jessica M., Lucas, Terra, Madaan, Shreshtha, Mattie, Kristin, McKenna, Danielle, Montgomery, Susan, Nielsen, Sarah, Powers, Jacquelyn, Rainey, Kim, Rybak, Christina, Savage, Michelle, Seelaus, Christina, Stoll, Jessica, Stopfer, Jill E., Yao, Xinxin (Shirley), Domchek, Susan M., Bradbury, Angela R.
Publicado 2020

A Single-Dose Intranasal ChAd Vaccine Protects Upper and Lower Respiratory Tracts against SARS-CoV-2

por Hassan, Ahmed O., Kafai, Natasha M., Dmitriev, Igor P., Fox, Julie M., Smith, Brittany K., Harvey, Ian B., Chen, Rita E., Winkler, Emma S., Wessel, Alex W., Case, James Brett, Kashentseva, Elena, McCune, Broc T., Bailey, Adam L., Zhao, Haiyan, VanBlargan, Laura A., Dai, Ya-Nan, Ma, Meisheng, Adams, Lucas J., Shrihari, Swathi, Danis, Jonathan E., Gralinski, Lisa E., Hou, Yixuan J., Schäfer, Alexandra, Kim, Arthur S., Keeler, Shamus P., Weiskopf, Daniela, Baric, Ralph S., Holtzman, Michael J., Fremont, Daved H., Curiel, David T., Diamond, Michael S.
Publicado 2020

Drug retention, inactive disease and response rates in 1860 patients with axial spondyloarthritis initiating secukinumab treatment: routine care data from 13 registries in the Euro...

por Michelsen, Brigitte, Lindström, Ulf, Codreanu, Catalin, Ciurea, Adrian, Zavada, Jakub, Loft, Anne Gitte, Pombo-Suarez, Manuel, Onen, Fatos, Kvien, Tore K, Rotar, Ziga, Santos, Maria Jose, Iannone, Florenzo, Hokkanen, Anna-Mari, Gudbjornsson, Bjorn, Askling, Johan, Ionescu, Ruxandra, Nissen, Michael J, Pavelka, Karel, Sanchez-Piedra, Carlos, Akar, Servet, Sexton, Joseph, Tomsic, Matija, Santos, Helena, Sebastiani, Marco, Österlund, Jenny, Geirsson, Arni Jon, Macfarlane, Gary, van der Horst-Bruinsma, Irene, Georgiadis, Stylianos, Brahe, Cecilie Heegaard, Ørnbjerg, Lykke Midtbøll, Hetland, Merete Lund, Østergaard, Mikkel
Publicado 2020

Rare CNVs and phenome-wide profiling highlight brain structural divergence and phenotypical convergence

por Kopal, Jakub, Kumar, Kuldeep, Saltoun, Karin, Modenato, Claudia, Moreau, Clara A., Martin-Brevet, Sandra, Huguet, Guillaume, Jean-Louis, Martineau, Martin, Charles-Olivier, Saci, Zohra, Younis, Nadine, Tamer, Petra, Douard, Elise, Maillard, Anne M., Rodriguez-Herreros, Borja, Pain, Aurélie, Richetin, Sonia, Kushan, Leila, Silva, Ana I., van den Bree, Marianne B. M., Linden, David E. J., Owen, Michael J., Hall, Jeremy, Lippé, Sarah, Draganski, Bogdan, Sønderby, Ida E., Andreassen, Ole A., Glahn, David C., Thompson, Paul M., Bearden, Carrie E., Jacquemont, Sébastien, Bzdok, Danilo
Publicado 2023

Localized Structural Alterations Underlying a Subset of Unexplained Sudden Cardiac Death

por Haïssaguerre, Michel, Hocini, Mélèze, Cheniti, Ghassen, Duchateau, Josselin, Sacher, Frédéric, Puyo, Stéphane, Cochet, Hubert, Takigawa, Masateru, Denis, Arnaud, Martin, Ruairidh, Derval, Nicolas, Bordachar, Pierre, Ritter, Philippe, Ploux, Sylvain, Pambrun, Thomas, Klotz, Nicolas, Massoullié, Gregoire, Pillois, Xavier, Dallet, Corentin, Schott, Jean-Jacques, Scouarnec, Solena, Ackerman, Michael J., Tester, David, Piot, Olivier, Pasquié, Jean-Luc, Leclerc, Christophe, Hermida, Jean-Sylvain, Gandjbakhch, Estelle, Maury, Philippe, Labrousse, Louis, Coronel, Ruben, Jais, Pierre, Benoist, David, Vigmond, Edward, Potse, Mark, Walton, Richard, Nademanee, Koonlawee, Bernus, Olivier, Dubois, Remi
Publicado 2018

Temporal and spatial heterogeneity of host response to SARS-CoV-2 pulmonary infection

por Desai, Niyati, Neyaz, Azfar, Szabolcs, Annamaria, Shih, Angela R., Chen, Jonathan H., Thapar, Vishal, Nieman, Linda T., Solovyov, Alexander, Mehta, Arnav, Lieb, David J., Kulkarni, Anupriya S., Jaicks, Christopher, Xu, Katherine H., Raabe, Michael J., Pinto, Christopher J., Juric, Dejan, Chebib, Ivan, Colvin, Robert B., Kim, Arthur Y., Monroe, Robert, Warren, Sarah E., Danaher, Patrick, Reeves, Jason W., Gong, Jingjing, Rueckert, Erroll H., Greenbaum, Benjamin D., Hacohen, Nir, Lagana, Stephen M., Rivera, Miguel N., Sholl, Lynette M., Stone, James R., Ting, David T., Deshpande, Vikram
Publicado 2020

A unique viral reservoir landscape in HIV-1 elite controllers

por Jiang, Chenyang, Lian, Xiaodong, Gao, Ce, Sun, Xiaoming, Einkauf, Kevin B., Chevalier, Joshua M., Chen, Samantha M.Y., Hua, Stephane, Rhee, Ben, Chang, Kaylee, Blackmer, Jane E., Osborn, Matthew, Peluso, Michael J., Hoh, Rebecca, Somsouk, Ma, Milush, Jeffrey, Bertagnolli, Lynn N., Sweet, Sarah E., Varriale, Joseph A., Burbelo, Peter D., Chun, Tae-Wook, Laird, Gregory M., Serrao, Erik, Engelman, Alan N., Carrington, Mary, Siliciano, Robert F., Siliciano, Janet M., Deeks, Steven G., Walker, Bruce D., Lichterfeld, Mathias, Yu, Xu G.
Publicado 2020

Time for a Fully Integrated Nonclinical–Clinical Risk Assessment to Streamline QT Prolongation Liability Determinations: A Pharma Industry Perspective

por Vargas, Hugo M., Rolf, Michael G., Wisialowski, Todd A., Achanzar, William, Bahinski, Anthony, Bass, Alan, Benson, Charles T, Chaudhary, Khuram W., Couvreur, Nicolas, Dota, Corina, Engwall, Michael J, Michael Foley, C., Gallacher, David, Greiter‐Wilke, Andrea, Guillon, Jean‐Michel, Guth, Brian, Himmel, Herbert M., Hegele‐Hartung, Christa, Ito, Maki, Jenkinson, Stephen, Chiba, Katsuyoshi, Lagrutta, Armando, Levesque, Paul, Martel, Eric, Okai, Yoshiko, Peri, Ravikumar, Pointon, Amy, Qu, Yusheng, Teisman, Ard, Traebert, Martin, Yoshinaga, Takashi, Gintant, Gary A., Leishman, Derek J., Valentin, Jean‐Pierre
Publicado 2020

PREVENTion of CLots in Orthopaedic Trauma (PREVENT CLOT): a randomised pragmatic trial protocol comparing aspirin versus low-molecular-weight heparin for blood clot prevention in o...

por O'Toole, Robert V, Stein, Deborah M, Frey, Katherine P, O'Hara, Nathan N, Scharfstein, Daniel O, Slobogean, Gerard P, Taylor, Tara J, Haac, Bryce E, Carlini, Anthony R, Manson, Theodore T, Sudini, Kuladeep, Mullins, C Daniel, Wegener, Stephen T, Firoozabadi, Reza, Haut, Elliott R, Bosse, Michael J, Seymour, Rachel B, Holden, Martha B, Gitajn, Ida Leah, Goldhaber, Samuel Z, Eastman, Alexander L, Jurkovich, Gregory J, Vallier, Heather A, Gary, Joshua L, Kleweno, Conor P, Cuschieri, Joseph, Marvel, Debra, Castillo, Renan C
Publicado 2021

Identifying key questions in the ecology and evolution of cancer

por Dujon, Antoine M., Aktipis, Athena, Alix‐Panabières, Catherine, Amend, Sarah R., Boddy, Amy M., Brown, Joel S., Capp, Jean‐Pascal, DeGregori, James, Ewald, Paul, Gatenby, Robert, Gerlinger, Marco, Giraudeau, Mathieu, Hamede, Rodrigo K., Hansen, Elsa, Kareva, Irina, Maley, Carlo C., Marusyk, Andriy, McGranahan, Nicholas, Metzger, Michael J., Nedelcu, Aurora M., Noble, Robert, Nunney, Leonard, Pienta, Kenneth J., Polyak, Kornelia, Pujol, Pascal, Read, Andrew F., Roche, Benjamin, Sebens, Susanne, Solary, Eric, Staňková, Kateřina, Swain Ewald, Holly, Thomas, Frédéric, Ujvari, Beata
Publicado 2021

Health disparities and treatment approaches in portopulmonary hypertension and idiopathic pulmonary arterial hypertension: an analysis of the Pulmonary Hypertension Association Reg...

por DuBrock, Hilary M., Burger, Charles D., Bartolome, Sonja D., Feldman, Jeremy P., Ivy, D. Dunbar, Rosenzweig, Erika B., Sager, Jeffrey S., Presberg, Kenneth W., Mathai, Stephen C., Lammi, Matthew R., Klinger, James R., Eggert, Michael, De Marco, Teresa, Elwing, Jean M., Badesch, David, Bull, Todd M., Cadaret, Linda M., Ramani, Gautam, Thenappan, Thenappan, Ford, H. James, Al-Naamani, Nadine, Simon, Marc A., Mazimba, Sula, Runo, James R., Chakinala, Murali, Horn, Evelyn M., Ryan, John J., Frantz, Robert P., Krowka, Michael J.
Publicado 2021