Serial liquid biopsies for detection of treatment failure and profiling of resistance mechanisms in KLC1–ALK-rearranged lung cancer

por Dietz, Steffen, Christopoulos, Petros, Gu, Lisa, Volckmar, Anna-Lena, Endris, Volker, Yuan, Zhao, Ogrodnik, Simon J., Zemojtel, Tomasz, Heussel, Claus-Peter, Schneider, Marc A., Meister, Michael, Muley, Thomas, Reck, Martin, Schlesner, Matthias, Thomas, Michael, Stenzinger, Albrecht, Sültmann, Holger
Publicado 2019

Validation of a blood protein signature for non-small cell lung cancer

por Mehan, Michael R, Williams, Stephen A, Siegfried, Jill M, Bigbee, William L, Weissfeld, Joel L, Wilson, David O, Pass, Harvey I, Rom, William N, Muley, Thomas, Meister, Michael, Franklin, Wilbur, Miller, York E, Brody, Edward N, Ostroff, Rachel M
Publicado 2014

Non-small cell lung cancer is characterized by dramatic changes in phospholipid profiles

por Marien, Eyra, Meister, Michael, Muley, Thomas, Fieuws, Steffen, Bordel, Sergio, Derua, Rita, Spraggins, Jeffrey, Van de Plas, Raf, Dehairs, Jonas, Wouters, Jens, Bagadi, Muralidhararao, Dienemann, Hendrik, Thomas, Michael, Schnabel, Philipp A, Caprioli, Richard M, Waelkens, Etienne, Swinnen, Johannes V
Publicado 2015

Consolidation Immunotherapy After Platinum-Based Chemoradiotherapy in Patients With Unresectable Stage III Non-Small Cell Lung Cancer—Cross-Sectional Study of Eligibility and Admin...

por Eichkorn, Tanja, Bozorgmehr, Farastuk, Regnery, Sebastian, Dinges, Lisa A., Kudak, Andreas, Bougatf, Nina, Weber, Dorothea, Christopoulos, Petros, Muley, Thomas, Kobinger, Sonja, König, Laila, Hörner-Rieber, Juliane, Adeberg, Sebastian, Heussel, Claus Peter, Thomas, Michael, Debus, Jürgen, El Shafie, Rami A.
Publicado 2020

Clinical Significance of SERPINA1 Gene and Its Encoded Alpha1-Antitrypsin Protein in NSCLC

por Ercetin, Evrim, Richtmann, Sarah, Martinez Delgado, Beatriz, Gomez-Mariano, Gema, Wrenger, Sabine, Korenbaum, Elena, Liu, Bin, DeLuca, David, Kühnel, Mark P., Jonigk, Danny, Yuskaeva, Kadriya, Warth, Arne, Muley, Thomas, Winter, Hauke, Meister, Michael, Welte, Tobias, Janciauskiene, Sabina, Schneider, Marc A.
Publicado 2019

Mass Spectrometry Imaging for Reliable and Fast Classification of Non-Small Cell Lung Cancer Subtypes

por Kriegsmann, Mark, Zgorzelski, Christiane, Casadonte, Rita, Schwamborn, Kristina, Muley, Thomas, Winter, Hauke, Eichhorn, Martin, Eichhorn, Florian, Warth, Arne, Deininger, Soeren-Oliver, Christopoulos, Petros, Thomas, Michael, Longerich, Thomas, Stenzinger, Albrecht, Weichert, Wilko, Müller-Tidow, Carsten, Kriegsmann, Jörg, Schirmacher, Peter, Kriegsmann, Katharina
Publicado 2020

A gene expression signature associated with B cells predicts benefit from immune checkpoint blockade in lung adenocarcinoma

por Budczies, Jan, Kirchner, Martina, Kluck, Klaus, Kazdal, Daniel, Glade, Julia, Allgäuer, Michael, Kriegsmann, Mark, Heußel, Claus-Peter, Herth, Felix J., Winter, Hauke, Meister, Michael, Muley, Thomas, Fröhling, Stefan, Peters, Solange, Seliger, Barbara, Schirmacher, Peter, Thomas, Michael, Christopoulos, Petros, Stenzinger, Albrecht
Publicado 2021

An integrated multiomic and quantitative label-free microscopy-based approach to study pro-fibrotic signalling in ex vivo human precision-cut lung slices

por Khan, Muzamil Majid, Poeckel, Daniel, Halavatyi, Aliaksandr, Zukowska-Kasprzyk, Joanna, Stein, Frank, Vappiani, Johanna, Sevin, Daniel C., Tischer, Christian, Zinn, Nico, Eley, Jessica D., Gudmann, Natasja Stæhr, Muley, Thomas, Winter, Hauke, Fisher, Andrew J., Nanthakumar, Carmel B., Bergamini, Giovanna, Pepperkok, Rainer
Publicado 2021

Comparison of the sensitivity of different criteria to select lung cancer patients for screening in a cohort of German patients

por Walter, Julia, Kauffmann‐Guerrero, Diego, Muley, Thomas, Reck, Martin, Fuge, Jan, Günther, Andreas, Majeed, Raphael W., Savai, Rajkumar, Koch, Ina, Dinkel, Julien, Schneider, Christian, Senghas, Karsten, Kobinger, Sonja, Manapov, Farkhad, Thomas, Michael, Kahnert, Kathrin, Winter, Hauke, Behr, Jürgen, Tammemägi, Martin, Tufman, Amanda
Publicado 2023

Real-world implementation of sequential targeted therapies for EGFR-mutated lung cancer

por Magios, Nikolaus, Bozorgmehr, Farastuk, Volckmar, Anna-Lena, Kazdal, Daniel, Kirchner, Martina, Herth, Felix J., Heussel, Claus-Peter, Eichhorn, Florian, Meister, Michael, Muley, Thomas, Elshafie, Rami A., Fischer, Jürgen R., Faehling, Martin, Kriegsmann, Mark, Schirmacher, Peter, Bischoff, Helge, Stenzinger, Albrecht, Thomas, Michael, Christopoulos, Petros
Publicado 2021

Preliminary results from the EMoLung clinical study showing early lung cancer detection by the LC score

por Rubio, Karla, Müller, Jason M., Mehta, Aditi, Watermann, Iris, Olchers, Till, Koch, Ina, Wessels, Sabine, Schneider, Marc A., Araujo-Ramos, Tania, Singh, Indrabahadur, Kugler, Christian, Stoleriu, Mircea Gabriel, Kriegsmann, Mark, Eichhorn, Martin, Muley, Thomas, Merkel, Olivia M., Braun, Thomas, Ammerpohl, Ole, Reck, Martin, Tresch, Achim, Barreto, Guillermo
Publicado 2023

Comprehensive serial biobanking in advanced NSCLC: feasibility, challenges and perspectives

por Wessels, Sabine, Muley, Thomas, Christopoulos, Petros, Meister, Michael, Heinzmann-Groth, Ingrid, Warth, Arne, Herpel, Esther, Hummler, Simone, Klingmüller, Ursula, Kuon, Jonas, Heussel, Claus-Peter, Eberhardt, Ralf, Herth, Felix J. F., Winter, Hauke, Bischoff, Helge, Stenzinger, Albrecht, Reck, Martin, Huber, Rudolf Maria, Thomas, Michael, Schneider, Marc A.
Publicado 2020

Longitudinal therapy monitoring of ALK-positive lung cancer by combined copy number and targeted mutation profiling of cell-free DNA

por Dietz, Steffen, Christopoulos, Petros, Yuan, Zhao, Angeles, Arlou Kristina, Gu, Lisa, Volckmar, Anna-Lena, Ogrodnik, Simon J., Janke, Florian, Fratte, Chiara Dalle, Zemojtel, Tomasz, Schneider, Marc A., Kazdal, Daniel, Endris, Volker, Meister, Michael, Muley, Thomas, Cecchin, Erika, Reck, Martin, Schlesner, Matthias, Thomas, Michael, Stenzinger, Albrecht, Sültmann, Holger
Publicado 2020

GHSR DNA hypermethylation is a common epigenetic alteration of high diagnostic value in a broad spectrum of cancers

por Moskalev, Evgeny A., Jandaghi, Pouria, Fallah, Mahdi, Manoochehri, Mehdi, Botla, Sandeep K., Kolychev, Oleg V., Nikitin, Evgeny A., Bubnov, Vladymyr V., von Knebel Doeberitz, M., Strobel, Oliver, Hackert, Thilo, Büchler, Markus W., Giese, Nathalia, Bauer, Andrea, Muley, Thomas, Warth, Arne, Schirmacher, Peter, Haller, Florian, Hoheisel, Jörg D., Riazalhosseini, Yasser
Publicado 2015

Deep Learning for the Classification of Small-Cell and Non-Small-Cell Lung Cancer

por Kriegsmann, Mark, Haag, Christian, Weis, Cleo-Aron, Steinbuss, Georg, Warth, Arne, Zgorzelski, Christiane, Muley, Thomas, Winter, Hauke, Eichhorn, Martin E., Eichhorn, Florian, Kriegsmann, Joerg, Christopolous, Petros, Thomas, Michael, Witzens-Harig, Mathias, Sinn, Peter, von Winterfeld, Moritz, Heussel, Claus Peter, Herth, Felix J. F., Klauschen, Frederick, Stenzinger, Albrecht, Kriegsmann, Katharina
Publicado 2020

Deciphering the immunosuppressive tumor microenvironment in ALK- and EGFR-positive lung adenocarcinoma

por Budczies, Jan, Kirchner, Martina, Kluck, Klaus, Kazdal, Daniel, Glade, Julia, Allgäuer, Michael, Kriegsmann, Mark, Heußel, Claus-Peter, Herth, Felix J., Winter, Hauke, Meister, Michael, Muley, Thomas, Goldmann, Torsten, Fröhling, Stefan, Wermke, Martin, Waller, Cornelius F., Tufman, Amanda, Reck, Martin, Peters, Solange, Schirmacher, Peter, Thomas, Michael, Christopoulos, Petros, Stenzinger, Albrecht
Publicado 2021

Early Assessment of Chemotherapy Response in Advanced Non-Small Cell Lung Cancer with Circulating Tumor DNA

por Yaung, Stephanie J., Woestmann, Corinna, Ju, Christine, Ma, Xiaoju Max, Gattam, Sandeep, Zhou, Yiyong, Xi, Liu, Pal, Subrata, Balasubramanyam, Aarthi, Tikoo, Nalin, Heussel, Claus Peter, Thomas, Michael, Kriegsmann, Mark, Meister, Michael, Schneider, Marc A., Herth, Felix J., Wehnl, Birgit, Diehn, Maximilian, Alizadeh, Ash A., Palma, John F., Muley, Thomas
Publicado 2022

Phospholipid profiling identifies acyl chain elongation as a ubiquitous trait and potential target for the treatment of lung squamous cell carcinoma

por Marien, Eyra, Meister, Michael, Muley, Thomas, del Pulgar, Teresa Gomez, Derua, Rita, Spraggins, Jeffrey M., Van de Plas, Raf, Vanderhoydonc, Frank, Machiels, Jelle, Binda, Maria Mercedes, Dehairs, Jonas, Willette-Brown, Jami, Hu, Yinling, Dienemann, Hendrik, Thomas, Michael, Schnabel, Philipp A., Caprioli, Richard M., Lacal, Juan Carlos, Waelkens, Etienne, Swinnen, Johannes V.
Publicado 2016

Conditional deletion of Nedd4-2 in lung epithelial cells causes progressive pulmonary fibrosis in adult mice

por Duerr, Julia, Leitz, Dominik H. W., Szczygiel, Magdalena, Dvornikov, Dmytro, Fraumann, Simon G., Kreutz, Clemens, Zadora, Piotr K., Seyhan Agircan, Ayça, Konietzke, Philip, Engelmann, Theresa A., Hegermann, Jan, Mulugeta, Surafel, Kawabe, Hiroshi, Knudsen, Lars, Ochs, Matthias, Rotin, Daniela, Muley, Thomas, Kreuter, Michael, Herth, Felix J. F., Wielpütz, Mark O., Beers, Michael F., Klingmüller, Ursula, Mall, Marcus A.
Publicado 2020

Conventional and semi-automatic histopathological analysis of tumor cell content for multigene sequencing of lung adenocarcinoma

por Kazdal, Daniel, Rempel, Eugen, Oliveira, Cristiano, Allgäuer, Michael, Harms, Alexander, Singer, Kerstin, Kohlwes, Elke, Ormanns, Steffen, Fink, Ludger, Kriegsmann, Jörg, Leichsenring, Michael, Kriegsmann, Katharina, Stögbauer, Fabian, Tavernar, Luca, Leichsenring, Jonas, Volckmar, Anna-Lena, Longuespée, Rémi, Winter, Hauke, Eichhorn, Martin, Heußel, Claus Peter, Herth, Felix, Christopoulos, Petros, Reck, Martin, Muley, Thomas, Weichert, Wilko, Budczies, Jan, Thomas, Michael, Peters, Solange, Warth, Arne, Schirmacher, Peter, Stenzinger, Albrecht, Kriegsmann, Mark
Publicado 2021