Towards optimizing peptide-based inhibitors of protein–protein interactions: predictive saturation variation scanning (PreSaVS)

por Hetherington, Kristina, Dutt, Som, Ibarra, Amaurys A., Cawood, Emma E., Hobor, Fruzsina, Woolfson, Derek N., Edwards, Thomas A., Nelson, Adam, Sessions, Richard B., Wilson, Andrew J.
Publicado 2021

Evaluation of fluoropyruvate as nucleophile in reactions catalysed by N-acetyl neuraminic acid lyase variants: scope, limitations and stereoselectivity

por Stockwell, Jennifer, Daniels, Adam D., Windle, Claire L., Harman, Thomas A., Woodhall, Thomas, Lebl, Tomas, Trinh, Chi H., Mulholland, Keith, Pearson, Arwen R., Berry, Alan, Nelson, Adam
Publicado 2016

Synthesis and Demonstration of the Biological Relevance of sp(3)‐rich Scaffolds Distantly Related to Natural Product Frameworks

por Foley, Daniel J., Craven, Philip G. E., Collins, Patrick M., Doveston, Richard G., Aimon, Anthony, Talon, Romain, Churcher, Ian, von Delft, Frank, Marsden, Stephen P., Nelson, Adam
Publicado 2017

OR05-01 Small Heterodimer Partner Modulates Antigen Presenting Myeloid Cells to Impair Regulatory T Cell Expansion, Promoting Anti-Tumor Immunity in Models of Breast Cancer

por Shahoei, Sayyed Hamed, Nelson, Adam T, Henn, Madeline A, Mathews, Ashley E, Chen, Joy J, Vembar, Varsha, Vardanyan, Anna, Ma, Liqian, Wang, Yu, Apetoh, Lionel, Nelson, Erik Russell
Publicado 2020

Evaluation of the significance of intermediate coronary artery stenoses by stress perfusion CMR

por Richardson, James D, Bertaso, Angela G, Tayeb, Hussam, Wong, Dennis, Nelson, Adam J, Dundon, Benjamin K, Molaee, Payman, Williams, Kerry, Worthley, Matthew I, Teo, Karen S, Worthley, Stephen G
Publicado 2011

Adenosine stress perfusion CMR accurately identifies the culprit vessel

por Richardson, James D, Bertaso, Angela G, Wong, Dennis, Nelson, Adam J, Tayeb, Hussam, Dundon, Benjamin K, Molaee, Payman, Williams, Kerry, Worthley, Matthew I, Teo, Karen S, Worthley, Stephen G
Publicado 2011

Prognostic value of adenosine stress perfusion cardiac magnetic resonance with late gadolinium enhancement

por Bertaso, Angela G, Richardson, James D, Wong, Dennis, Nelson, Adam J, Molaee, Payman, Tayeb, Hussam, Dundon, Benjamin K, Williams, Kerry, Worthley, Matthew I, Teo, Karen S, Worthley, Stephen G
Publicado 2011

Identification of Dihydroorotate Dehydrogenase Inhibitors Using the Cell Painting Assay

por Schölermann, Beate, Bonowski, Jana, Grigalunas, Michael, Burhop, Annina, Xie, Yusheng, Hoock, Joseph G. F., Liu, Jie, Dow, Mark, Nelson, Adam, Nowak, Christine, Pahl, Axel, Sievers, Sonja, Ziegler, Slava
Publicado 2022

Practical Application of Patient-Reported Health Status Measures for Transcatheter Valve Therapies: Insights From the Society of Thoracic Surgeons/American College of Cardiology Tr...

por Hejjaji, Vittal, Cohen, David J., Carroll, John D., Li, Zhuokai, Manandhar, Pratik, Vemulapalli, Sreekanth, Nelson, Adam J., Malik, Ali O., Mack, Michael J., Spertus, John A., Arnold, Suzanne V.
Publicado 2021

Validation of cardiovascular magnetic resonance assessment of pericardial adipose tissue volume

por Nelson, Adam J, Worthley, Matthew I, Psaltis, Peter J, Carbone, Angelo, Dundon, Benjamin K, Duncan, Rae F, Piantadosi, Cynthia, Lau, Dennis H, Sanders, Prashanthan, Wittert, Gary A, Worthley, Stephen G
Publicado 2009

Proximal aortic stiffness in the paediatric adolescent population

por Nelson, Adam J, Cameron, James D, Kaihui, Adelene C, Carbone, Angelo, Willoughby, Scott R, van den Heuvel, Cameron J, Martin, James A, Kennedy, Declan, Worthley, Stephen G, Worthley, Matthew I
Publicado 2011

Reaction Mechanism of N-Acetylneuraminic Acid Lyase Revealed by a Combination of Crystallography, QM/MM Simulation, and Mutagenesis

por Daniels, Adam D., Campeotto, Ivan, van der Kamp, Marc W., Bolt, Amanda H., Trinh, Chi H., Phillips, Simon E. V., Pearson, Arwen R., Nelson, Adam, Mulholland, Adrian J., Berry, Alan
Publicado 2014

Stress perfusion CMR reliably risk stratifies patients with prior exercise treadmill testing

por Bertaso, Angela G, Richardson, James D, Nelson, Adam J, Wong1, Dennis, Tayeb, Hussam, Dundon, Benjamin K, Molaee, Payman, Awwad, George, Williams, Kerry, Worthley, Matthew I, Teo, Karen S, Worthley, Stephen G
Publicado 2011

Comprehensive assessment of estrogen receptor beta antibodies in cancer cell line models and tissue reveals critical limitations in reagent specificity

por Nelson, Adam W., Groen, Arnoud J., Miller, Jodi L., Warren, Anne Y., Holmes, Kelly A., Tarulli, Gerard A., Tilley, Wayne D., Katzenellenbogen, Benita S., Hawse, John R., Gnanapragasam, Vincent J., Carroll, Jason S.
Publicado 2017

Donor Selection in a Geographically Isolated Country during the COVID-19 Pandemic

por Chapman, Laura RM, Oswald, Cecilia, Cain, Lucy E, Araya, Milica, Coulits, Nelly, Maurice, Lucy C, McCleary, Karen, Moses, Jonathan, Mitchell, Richard, OBrien, Tracey A, Wright, Felicity A, Trickett, Annette, Nelson, Adam S
Publicado 2022

Predicting and Experimentally Validating Hot-Spot Residues at Protein–Protein Interfaces

por Ibarra, Amaurys A., Bartlett, Gail J., Hegedüs, Zsöfia, Dutt, Som, Hobor, Fruzsina, Horner, Katherine A., Hetherington, Kristina, Spence, Kirstin, Nelson, Adam, Edwards, Thomas A., Woolfson, Derek N., Sessions, Richard B., Wilson, Andrew J.
Publicado 2019

Ten things to know about ten cardiovascular disease risk factors – 2022

por Bays, Harold E, Kulkarni, Anandita, German, Charles, Satish, Priyanka, Iluyomade, Adedapo, Dudum, Ramzi, Thakkar, Aarti, Rifai, Mahmoud Al, Mehta, Anurag, Thobani, Aneesha, Al-Saiegh, Yousif, Nelson, Adam J, Sheth, Samip, Toth, Peter P.
Publicado 2022

Gaps in Evidence‐Based Therapy Use in Insured Patients in the United States With Type 2 Diabetes Mellitus and Atherosclerotic Cardiovascular Disease

por Nelson, Adam J., Ardissino, Maddalena, Haynes, Kevin, Shambhu, Sonali, Eapen, Zubin J., McGuire, Darren K., Carnicelli, Anthony, Lopes, Renato D., Green, Jennifer B., O’Brien, Emily C., Pagidipati, Neha J., Granger, Christopher B.
Publicado 2021

C-reactive protein levels and plaque regression with evolocumab: Insights from GLAGOV

por Nelson, Adam J., Puri, Rishi, Brennan, Danielle M., Anderson, Todd J., Cho, Leslie, Ballantyne, Christie M., Kastelein, John JP., Koenig, Wolfgang, Kassahun, Helina, Somaratne, Ransi M., Wasserman, Scott M., Nissen, Steven E., Nicholls, Stephen J.
Publicado 2020

Query-guided protein–protein interaction inhibitor discovery

por Celis, Sergio, Hobor, Fruzsina, James, Thomas, Bartlett, Gail J., Ibarra, Amaurys A., Shoemark, Deborah K., Hegedüs, Zsófia, Hetherington, Kristina, Woolfson, Derek N., Sessions, Richard B., Edwards, Thomas A., Andrews, David M., Nelson, Adam, Wilson, Andrew J.
Publicado 2021