Pembrolizumab versus paclitaxel for previously treated PD-L1-positive advanced gastric or gastroesophageal junction cancer: 2-year update of the randomized phase 3 KEYNOTE-061 tria...

por Fuchs, Charles S., Özgüroğlu, Mustafa, Bang, Yung-Jue, Di Bartolomeo, Maria, Mandala, Mario, Ryu, Min-Hee, Fornaro, Lorenzo, Olesinski, Tomasz, Caglevic, Christian, Chung, Hyun C., Muro, Kei, Van Cutsem, Eric, Elme, Anneli, Thuss-Patience, Peter, Chau, Ian, Ohtsu, Atsushi, Bhagia, Pooja, Wang, Anran, Shih, Chie-Schin, Shitara, Kohei
Publicado 2021

A gain-of-function screen to identify genes that reduce lifespan in the adult of Drosophila melanogaster

por Nakayama, Minoru, Ishibashi, Tomoki, Ishikawa, Hiroyuki O, Sato, Hiroyasu, Usui, Takao, Okuda, Takayuki, Yashiro, Hiroyuki, Ishikawa, Hironori, Taikou, Yoshie, Minami, Asako, Kato, Kengo, Taki, Masataka, Aigaki, Toshiro, Gunji, Wataru, Ohtsu, Masaya, Murakami, Yasufumi, Tanuma, Sei-ichi, Tsuboi, Alice, Adachi, Mai, Kuroda, Junpei, Sasamura, Takeshi, Yamakawa, Tomoko, Matsuno, Kenji
Publicado 2014

Regulation of MEK inhibitor selumetinib sensitivity by AKT phosphorylation in the novel BRAF L525R mutant

por Nakai, Chikako, Mimaki, Sachiyo, Matsushima, Koutatsu, Shinozaki, Eiji, Yamazaki, Kentaro, Muro, Kei, Yamaguchi, Kensei, Nishina, Tomohiro, Yuki, Satoshi, Shitara, Kohei, Bando, Hideaki, Suzuki, Yutaka, Akagi, Kiwamu, Nomura, Shogo, Fujii, Satoshi, Sugiyama, Masaya, Nishida, Nao, Mizokami, Masashi, Koh, Yasuhiro, Koshizaka, Takuya, Okada, Hideki, Abe, Yukiko, Ohtsu, Atsushi, Yoshino, Takayuki, Tsuchihara, Katsuya
Publicado 2023

Clinical significance of BRAF non-V600E mutations on the therapeutic effects of anti-EGFR monoclonal antibody treatment in patients with pretreated metastatic colorectal cancer: th...

por Shinozaki, Eiji, Yoshino, Takayuki, Yamazaki, Kentaro, Muro, Kei, Yamaguchi, Kensei, Nishina, Tomohiro, Yuki, Satoshi, Shitara, Kohei, Bando, Hideaki, Mimaki, Sachiyo, Nakai, Chikako, Matsushima, Koutatsu, Suzuki, Yutaka, Akagi, Kiwamu, Yamanaka, Takeharu, Nomura, Shogo, Fujii, Satoshi, Esumi, Hiroyasu, Sugiyama, Masaya, Nishida, Nao, Mizokami, Masashi, Koh, Yasuhiro, Abe, Yukiko, Ohtsu, Atsushi, Tsuchihara, Katsuya
Publicado 2017

High-Density Lipoprotein Cholesterol and Cardiovascular Events in Patients with Stable Coronary Artery Disease Treated with Statins: An Observation from the REAL-CAD Study

por Omote, Kazunori, Yokota, Isao, Nagai, Toshiyuki, Sakuma, Ichiro, Nakagawa, Yoshihisa, Kamiya, Kiwamu, Iwata, Hiroshi, Miyauchi, Katsumi, Ozaki, Yukio, Hibi, Kiyoshi, Hiro, Takafumi, Fukumoto, Yoshihiro, Mori, Hiroyoshi, Hokimoto, Seiji, Ohashi, Yasuo, Ohtsu, Hiroshi, Ogawa, Hisao, Daida, Hiroyuki, Iimuro, Satoshi, Shimokawa, Hiroaki, Saito, Yasushi, Kimura, Takeshi, Matsuzaki, Masunori, Nagai, Ryozo, Anzai, Toshihisa
Publicado 2022

Circulating tumor DNA-guided treatment with pertuzumab plus trastuzumab for HER2-amplified metastatic colorectal cancer: a phase 2 trial

por Nakamura, Yoshiaki, Okamoto, Wataru, Kato, Takeshi, Esaki, Taito, Kato, Ken, Komatsu, Yoshito, Yuki, Satoshi, Masuishi, Toshiki, Nishina, Tomohiro, Ebi, Hiromichi, Sawada, Kentaro, Taniguchi, Hiroya, Fuse, Nozomu, Nomura, Shogo, Fukui, Makoto, Matsuda, Seiko, Sakamoto, Yasutoshi, Uchigata, Hiroshi, Kitajima, Kana, Kuramoto, Naomi, Asakawa, Takashi, Olsen, Steve, Odegaard, Justin I., Sato, Akihiro, Fujii, Satoshi, Ohtsu, Atsushi, Yoshino, Takayuki
Publicado 2021

Synergistic Effect of Motivation for the Elderly and Support for Going out

por Mashimo, Yumi, Tsuchihashi, Saki, Tsutsui, Kenta, Arai, Tomoyuki, Tsuji, Yoshitaka, Numai, Toshiaki, Kameda, Kazuo, Nishizawa, Kyoko, Kovacs, Mami, Tanaka, Shukichi, Watanabe, Hiroki, Naruse, Yasushi, Ohmura, Mitsuyo, Ishida, Noriyuki, Iwasaki, Toshiki, Hiruma, Gaku, Miyazaki, Naoki, Takemura, Ryo, Nagashima, Kengo, Sato, Yasunori, Ohtsu, Yui, Nakano, Takashi, Aida, Naomi, Iizuka, Isao, Kato, Hiromi, Kobayashi, Yoshiki, Senbonmatsu, Takaaki
Publicado 2022

Neutropenia and survival outcomes in metastatic colorectal cancer patients treated with trifluridine/tipiracil in the RECOURSE and J003 trials

por Yoshino, T., Cleary, J. M., Van Cutsem, E., Mayer, R. J., Ohtsu, A., Shinozaki, E., Falcone, A., Yamazaki, K., Nishina, T., Garcia-Carbonero, R., Komatsu, Y., Baba, H., Argilés, G., Tsuji, A., Sobrero, A., Yamaguchi, K., Peeters, M., Muro, K., Zaniboni, A., Sugimoto, N., Shimada, Y., Tsuji, Y., Hochster, H. S., Moriwaki, T., Tran, B., Esaki, T., Hamada, C., Tanase, T., Benedetti, F., Makris, L., Yamashita, F., Lenz, H.-J.
Publicado 2020

Small Dense Low-Density Lipoprotein Cholesterol and Cardiovascular Risk in Statin-Treated Patients with Coronary Artery Disease

por Ishii, Junnichi, Kashiwabara, Kosuke, Ozaki, Yukio, Takahashi, Hiroshi, Kitagawa, Fumihiko, Nishimura, Hideto, Ishii, Hideki, Iimuro, Satoshi, Kawai, Hideki, Muramatsu, Takashi, Naruse, Hiroyuki, Iwata, Hiroshi, Tanizawa-Motoyama, Sadako, Ito, Hiroyasu, Watanabe, Eiichi, Matsuyama, Yutaka, Fukumoto, Yoshihiro, Sakuma, Ichiro, Nakagawa, Yoshihisa, Hibi, Kiyoshi, Hiro, Takafumi, Hokimoto, Seiji, Miyauchi, Katsumi, Ohtsu, Hiroshi, Izawa, Hideo, Ogawa, Hisao, Daida, Hiroyuki, Shimokawa, Hiroaki, Saito, Yasushi, Kimura, Takeshi, Matsuzaki, Masunori, Nagai, Ryozo
Publicado 2022

Efficacy of Targeted Trials and Signaling Pathway Landscape in Advanced Gastrointestinal Cancers From SCRUM-Japan GI-SCREEN: A Nationwide Genomic Profiling Program

por Nakamura, Yoshiaki, Yamashita, Riu, Okamoto, Wataru, Komatsu, Yoshito, Yuki, Satoshi, Ueno, Makoto, Kato, Ken, Taniguchi, Hiroya, Kagawa, Yoshinori, Denda, Tadamichi, Hara, Hiroki, Esaki, Taito, Moriwaki, Toshikazu, Sunakawa, Yu, Oki, Eiji, Nagashima, Fumio, Nishina, Tomohiro, Satoh, Taroh, Kawakami, Hisato, Yamaguchi, Kensei, Ohtsubo, Koushiro, Kato, Takeshi, Horita, Yosuke, Tsuji, Akihito, Yasui, Hisateru, Goto, Masahiro, Hamamoto, Yasuo, Wakabayashi, Masashi, Ikeno, Takashi, Shitara, Kohei, Bando, Hideaki, Tsuchihara, Katsuya, Miki, Izumi, Ichiki, Hiroko, Ohtsu, Atsushi, Yoshino, Takayuki
Publicado 2023

High-Dose Versus Low-Dose Pitavastatin in Japanese Patients With Stable Coronary Artery Disease (REAL-CAD): A Randomized Superiority Trial

por Taguchi, Isao, Iimuro, Satoshi, Iwata, Hiroshi, Takashima, Hiroaki, Abe, Mitsuru, Amiya, Eisuke, Ogawa, Takanori, Ozaki, Yukio, Sakuma, Ichiro, Nakagawa, Yoshihisa, Hibi, Kiyoshi, Hiro, Takafumi, Fukumoto, Yoshihiro, Hokimoto, Seiji, Miyauchi, Katsumi, Yamazaki, Tsutomu, Ito, Hiroshi, Otsuji, Yutaka, Kimura, Kazuo, Takahashi, Jun, Hirayama, Atsushi, Yokoi, Hiroyoshi, Kitagawa, Kazuo, Urabe, Takao, Okada, Yasushi, Terayama, Yasuo, Toyoda, Kazunori, Nagao, Takehiko, Matsumoto, Masayasu, Ohashi, Yasuo, Kaneko, Tetsuji, Fujita, Retsu, Ohtsu, Hiroshi, Ogawa, Hisao, Daida, Hiroyuki, Shimokawa, Hiroaki, Saito, Yasushi, Kimura, Takeshi, Inoue, Teruo, Matsuzaki, Masunori, Nagai, Ryozo
Publicado 2018

Effect of Early vs Delayed Surgical Treatment on Motor Recovery in Incomplete Cervical Spinal Cord Injury With Preexisting Cervical Stenosis: A Randomized Clinical Trial

por Chikuda, Hirotaka, Koyama, Yurie, Matsubayashi, Yoshitaka, Ogata, Toru, Ohtsu, Hiroshi, Sugita, Shurei, Sumitani, Masahiko, Kadono, Yuho, Miura, Toshiki, Tanaka, Sakae, Akiyama, Toru, Ando, Kei, Anno, Masato, Azuma, Seiichi, Endo, Kenji, Endo, Toru, Fujiyoshi, Takayuki, Furuya, Takeo, Hayashi, Hiroyuki, Higashikawa, Akiro, Hiyama, Akihiko, Horii, Chiaki, Iimoto, Seiji, Iizuka, Yoichi, Ikuma, Hisanori, Imagama, Shiro, Inokuchi, Koichi, Inoue, Hirokazu, Inoue, Tomoo, Ishii, Keisuke, Ishii, Masayoshi, Ito, Takui, Itoi, Akira, Iwamoto, Kohei, Iwasaki, Motoki, Kaito, Takashi, Kato, Tsuyoshi, Katoh, Hiroyuki, Kawaguchi, Yoshiharu, Kawano, Osamu, Kimura, Atsushi, Kobayashi, Kazuyoshi, Koda, Masao, Komatsu, Miki, Kumagai, Gentaro, Maeda, Takeshi, Makino, Takahiro, Mannoji, Chikato, Masuda, Kazuhiro, Masuda, Keisuke, Matsumoto, Koji, Matsumoto, Morio, Matsunaga, Shunji, Matsuyama, Yukihiro, Mieda, Tokue, Miyoshi, Kota, Mochida, Joji, Moridaira, Hiroshi, Motegi, Hiroyuki, Nakagawa, Yukihiro, Nohara, Yutaka, Oae, Kazunori, Ogawa, Shinji, Okazaki, Rentaro, Okuda, Akinori, Onishi, Eijiro, Ono, Atsushi, Oshima, Masashi, Oshita, Yusuke, Saita, Kazuo, Sasao, Yutaka, Sato, Kimiaki, Sawakami, Kimihiko, Seichi, Atsushi, Seki, Shoji, Shigematsu, Hideki, Suda, Kota, Takagi, Yasutaka, Takahashi, Masahito, Takahashi, Ryosuke, Takasawa, Eiji, Takenaka, Shota, Takeshita, Katsushi, Takeshita, Yujiro, Tokioka, Takamitsu, Tokuhashi, Yasuaki, Tonosu, Juichi, Uei, Hiroshi, Wada, Kanichiro, Watanabe, Masahiko, Yahata, Tadashi, Yamada, Kei, Yasuda, Taketoshi, Yasui, Keigo, Yoshii, Toshitaka
Publicado 2021