Beta cells in type 1 diabetes: mass and function; sleeping or dead?

por Oram, Richard A., Sims, Emily K., Evans-Molina, Carmella
Publicado 2019

Precision medicine in type 1 diabetes

por Carr, Alice L. J., Evans-Molina, Carmella, Oram, Richard A.
Publicado 2022

RET gene mutations are not a common cause of congenital solitary functioning kidney in adults

por Oram, Richard A., Edghill, Emma L., Woolf, Adrian S., Hennekam, R. C., Ellard, Sian, Hattersley, A. T., Bingham, Coralie
Publicado 2009

Frequency and phenotype of type 1 diabetes in the first six decades of life: a cross-sectional, genetically stratified survival analysis from UK Biobank

por Thomas, Nicholas J, Jones, Samuel E, Weedon, Michael N, Shields, Beverley M, Oram, Richard A, Hattersley, Andrew T
Publicado 2018

Utility of genetic risk scores in type 1 diabetes

por Luckett, Amber M., Weedon, Michael N., Hawkes, Gareth, Leslie, R. David, Oram, Richard A., Grant, Struan F. A.
Publicado 2023

Type 1 Diabetes Risk Phenotypes Using Cluster Analysis

por You, Lu, Ferrat, Lauric A., Oram, Richard A., Parikh, Hemang M., Steck, Andrea K., Krischer, Jeffrey, Redondo, Maria J.
Publicado 2023

Measurement of Peak C-Peptide at Diagnosis Informs Glycemic Control but not Hypoglycemia in Adults With Type 1 Diabetes

por Carr, Alice L J, Oram, Richard A, Marren, Shannon M, McDonald, Timothy J, Narendran, Parth, Andrews, Robert C
Publicado 2021

Prevalence of Fabry disease-causing variants in the UK Biobank

por Gilchrist, Mark, Casanova, Francesco, Tyrrell, Jess S, Cannon, Stuart, Wood, Andrew R, Fife, Nicole, Young, Katherine, Oram, Richard A, Weedon, Michael N
Publicado 2023

Logistic regression has similar performance to optimised machine learning algorithms in a clinical setting: application to the discrimination between type 1 and type 2 diabetes in...

por Lynam, Anita L., Dennis, John M., Owen, Katharine R., Oram, Richard A., Jones, Angus G., Shields, Beverley M., Ferrat, Lauric A.
Publicado 2020

Estimation of Early Graft Function Using the BETA-2 Score Following Clinical Islet Transplantation

por Lam, Anna, Oram, Richard A., Forbes, Shareen, Olateju, Tolu, Malcolm, Andrew J., Imes, Sharleen, Shapiro, A. M. James, Senior, Peter A.
Publicado 2022

Studies of insulin and proinsulin in pancreas and serum support the existence of aetiopathological endotypes of type 1 diabetes associated with age at diagnosis

por Leete, Pia, Oram, Richard A., McDonald, Timothy J., Shields, Beverley M., Ziller, Clemens, Hattersley, Andrew T., Richardson, Sarah J., Morgan, Noel G.
Publicado 2020

Urine C-peptide creatinine ratio can be used to assess insulin resistance and insulin production in people without diabetes: an observational study

por Oram, Richard A, Rawlingson, Andrew, Shields, Beverley M, Bingham, Coralie, Besser, Rachel E J, McDonald, Tim J, Knight, Bridget A, Hattersley, Andrew T
Publicado 2013

Methods for quick, accurate and cost-effective determination of the type 1 diabetes genetic risk score (T1D-GRS)

por Locke, Jonathan M., Latten, Mark J., Datta, Renu Y., Wood, Andrew R., Crockard, Martin A., Lamont, John V., Weedon, Michael N., Oram, Richard A.
Publicado 2020

The majority of patients with long-duration type 1 diabetes are insulin microsecretors and have functioning beta cells

por Oram, Richard A., Jones, Angus G., Besser, Rachel E. J., Knight, Bridget A., Shields, Beverley M., Brown, Richard J., Hattersley, Andrew T., McDonald, Timothy J.
Publicado 2013

Erratum to: The majority of patients with long-duration type 1 diabetes are insulin microsecretors and have functioning beta cells

por Oram, Richard A., Jones, Angus G., Besser, Rachel E. J., Knight, Bridget A., Shields, Beverley M., Brown, Richard J., Hattersley, Andrew T., McDonald, Timothy J.
Publicado 2013

Capturing the real‐world benefit of residual β‐cell function during clinically important time‐periods in established Type 1 diabetes

por Taylor, Guy S., Shaw, Andy C., Smith, Kieran, Wason, James, McDonald, Timothy J., Oram, Richard A., Stevenson, Emma, Shaw, James A. M., West, Daniel J.
Publicado 2022

Applying a genetic risk score for prostate cancer to men with lower urinary tract symptoms in primary care to predict prostate cancer diagnosis: a cohort study in the UK Biobank

por Green, Harry D., Merriel, Samuel W. D., Oram, Richard A., Ruth, Katherine S., Tyrrell, Jessica, Jones, Samuel E., Thirlwell, Chrissie, Weedon, Michael N., Bailey, Sarah E. R.
Publicado 2022

A Type 1 Diabetes Genetic Risk Score Predicts Progression of Islet Autoimmunity and Development of Type 1 Diabetes in Individuals at Risk

por Redondo, Maria J., Geyer, Susan, Steck, Andrea K., Sharp, Seth, Wentworth, John M., Weedon, Michael N., Antinozzi, Peter, Sosenko, Jay, Atkinson, Mark, Pugliese, Alberto, Oram, Richard A.
Publicado 2018

Type 1 diabetes defined by severe insulin deficiency occurs after 30 years of age and is commonly treated as type 2 diabetes

por Thomas, Nicholas J., Lynam, Anita L., Hill, Anita V., Weedon, Michael N., Shields, Beverley M., Oram, Richard A., McDonald, Timothy J., Hattersley, Andrew T., Jones, Angus G.
Publicado 2019

Estimating disease prevalence in large datasets using genetic risk scores

por Evans, Benjamin D., Słowiński, Piotr, Hattersley, Andrew T., Jones, Samuel E., Sharp, Seth, Kimmitt, Robert A., Weedon, Michael N., Oram, Richard A., Tsaneva-Atanasova, Krasimira, Thomas, Nicholas J.
Publicado 2021