Successful immune checkpoint blockade in a patient with advanced stage microsatellite-unstable biliary tract cancer

por Czink, Elena, Kloor, Matthias, Goeppert, Benjamin, Fröhling, Stefan, Uhrig, Sebastian, Weber, Tim F., Meinel, Jörn, Sutter, Christian, Weiss, Karl Heinz, Schirmacher, Peter, Doeberitz, Magnus von Knebel, Jäger, Dirk, Springfeld, Christoph
Publicado 2017

Genetic changes of non-small cell lung cancer under neoadjuvant therapy

por Warth, Arne, Endris, Volker, Stenzinger, Albrecht, Penzel, Roland, Harms, Alexander, Duell, Thomas, Abdollahi, Amir, Lindner, Michael, Schirmacher, Peter, Muley, Thomas, Dienemann, Hendrik, Fink, Ludger, Morresi-Hauf, Alicia, Pfarr, Nicole, Weichert, Wilko
Publicado 2016

Mutations in BRCA2 and taxane resistance in prostate cancer

por Nientiedt, Cathleen, Heller, Martina, Endris, Volker, Volckmar, Anna-Lena, Zschäbitz, Stefanie, Tapia-Laliena, María A., Duensing, Anette, Jäger, Dirk, Schirmacher, Peter, Sültmann, Holger, Stenzinger, Albrecht, Hohenfellner, Markus, Grüllich, Carsten, Duensing, Stefan
Publicado 2017

Spatial Tissue Proteomics Quantifies Inter- and Intratumor Heterogeneity in Hepatocellular Carcinoma (HCC)

por Buczak, Katarzyna, Ori, Alessandro, Kirkpatrick, Joanna M., Holzer, Kerstin, Dauch, Daniel, Roessler, Stephanie, Endris, Volker, Lasitschka, Felix, Parca, Luca, Schmidt, Alexander, Zender, Lars, Schirmacher, Peter, Krijgsveld, Jeroen, Singer, Stephan, Beck, Martin
Publicado 2018

Yes-associated protein (YAP) induces a secretome phenotype and transcriptionally regulates plasminogen activator Inhibitor-1 (PAI-1) expression in hepatocarcinogenesis

por Marquard, Simone, Thomann, Stefan, Weiler, Sofia M. E., Bissinger, Michaela, Lutz, Teresa, Sticht, Carsten, Tóth, Marcell, de la Torre, Carolina, Gretz, Norbert, Straub, Beate K., Marquardt, Jens, Schirmacher, Peter, Breuhahn, Kai
Publicado 2020

Programmed Death Ligand-1 (PD-L1) Is an Independent Negative Prognosticator in Western-World Gallbladder Cancer

por Albrecht, Thomas, Brinkmann, Fritz, Albrecht, Michael, Lonsdorf, Anke S., Mehrabi, Arianeb, Hoffmann, Katrin, Kulu, Yakup, Charbel, Alphonse, Vogel, Monika N., Rupp, Christian, Köhler, Bruno, Springfeld, Christoph, Schirmacher, Peter, Roessler, Stephanie, Goeppert, Benjamin
Publicado 2021

Spatial modeling reveals nuclear phosphorylation and subcellular shuttling of YAP upon drug-induced liver injury

por Wehling, Lilija, Keegan, Liam, Fernández-Palanca, Paula, Hassan, Reham, Ghallab, Ahmed, Schmitt, Jennifer, Tang, Yingyue, Le Marois, Maxime, Roessler, Stephanie, Schirmacher, Peter, Kummer, Ursula, Hengstler, Jan G, Sahle, Sven, Breuhahn, Kai
Publicado 2022

Spatiotemporal analysis of tumour-infiltrating immune cells in biliary carcinogenesis

por Charbel, Alphonse, Tavernar, Luca, Albrecht, Thomas, Brinkmann, Fritz, Verheij, Joanne, Roos, Eva, Vogel, Monika Nadja, Köhler, Bruno, Springfeld, Christoph, Brobeil, Alexander, Schirmacher, Peter, Singer, Stephan, Mehrabi, Arianeb, Roessler, Stephanie, Goeppert, Benjamin
Publicado 2022

Distinct Activities of Glycolytic Enzymes Identify Chronic Lymphocytic Leukemia Patients with a more Aggressive Course and Resistance to Chemo-Immunotherapy

por Gdynia, Georg, Robak, Tadeusz, Kopitz, Jürgen, Heller, Anette, Grekova, Svetlana, Duglova, Katarina, Laukemper, Gloria, Heinzel-Gutenbrunner, Monika, Gutenbrunner, Cornelius, Roth, Wilfried, Ho, Anthony D., Schirmacher, Peter, Schmitt, Michael, Dreger, Peter, Sellner, Leopold
Publicado 2018

NEMO Prevents Steatohepatitis and Hepatocellular Carcinoma by Inhibiting RIPK1 Kinase Activity-Mediated Hepatocyte Apoptosis

por Kondylis, Vangelis, Polykratis, Apostolos, Ehlken, Hanno, Ochoa-Callejero, Laura, Straub, Beate Katharina, Krishna-Subramanian, Santosh, Van, Trieu-My, Curth, Harald-Morten, Heise, Nicole, Weih, Falk, Klein, Ulf, Schirmacher, Peter, Kelliher, Michelle, Pasparakis, Manolis
Publicado 2015

Prognosis of breast cancer molecular subtypes in routine clinical care: A large prospective cohort study

por Hennigs, André, Riedel, Fabian, Gondos, Adam, Sinn, Peter, Schirmacher, Peter, Marmé, Frederik, Jäger, Dirk, Kauczor, Hans-Ulrich, Stieber, Anne, Lindel, Katja, Debus, Jürgen, Golatta, Michael, Schütz, Florian, Sohn, Christof, Heil, Jörg, Schneeweiss, Andreas
Publicado 2016

NEMO Prevents Steatohepatitis and Hepatocellular Carcinoma by Inhibiting RIPK1 Kinase Activity-Mediated Hepatocyte Apoptosis

por Kondylis, Vangelis, Polykratis, Apostolos, Ehlken, Hanno, Ochoa-Callejero, Laura, Straub, Beate Katharina, Krishna-Subramanian, Santosh, Van, Trieu-My, Curth, Harald-Morten, Heise, Nicole, Weih, Falk, Klein, Ulf, Schirmacher, Peter, Kelliher, Michelle, Pasparakis, Manolis
Publicado 2015

Robust prediction of gene regulation in colorectal cancer tissues from DNA methylation profiles

por Klett, Hagen, Balavarca, Yesilda, Toth, Reka, Gigic, Biljana, Habermann, Nina, Scherer, Dominique, Schrotz-King, Petra, Ulrich, Alexis, Schirmacher, Peter, Herpel, Esther, Brenner, Hermann, Ulrich, Cornelia M., Michels, Karin B., Busch, Hauke, Boerries, Melanie
Publicado 2018

STAT1 and STAT3 Exhibit a Crosstalk and Are Associated with Increased Inflammation in Hepatocellular Carcinoma

por Ploeger, Carolin, Schreck, Johannes, Huth, Thorben, Fraas, Angelika, Albrecht, Thomas, Charbel, Alphonse, Ji, Junfang, Singer, Stephan, Breuhahn, Kai, Pusch, Stefan, Köhler, Bruno Christian, Springfeld, Christoph, Schirmacher, Peter, Mehrabi, Arianeb, Goeppert, Benjamin, Roessler, Stephanie
Publicado 2022

Histological and molecular plasticity of ALK-positive non-small-cell lung cancer under targeted therapy: a case report

por Ball, Markus, Christopoulos, Petros, Kirchner, Martina, Allgäuer, Michael, Brandt, Regine, Winter, Hauke, Heußel, Claus Peter, Herth, Felix, Fröhling, Stefan, Savai, Rajkumar, Kriegsmann, Mark, Schirmacher, Peter, Peters, Solange, Thomas, Michael, Stenzinger, Albrecht, Kazdal, Daniel
Publicado 2022

Dysregulated serum response factor triggers formation of hepatocellular carcinoma

por Ohrnberger, Stefan, Thavamani, Abhishek, Braeuning, Albert, Lipka, Daniel B, Kirilov, Milen, Geffers, Robert, Authenrieth, Stella E, Römer, Michael, Zell, Andreas, Bonin, Michael, Schwarz, Michael, Schütz, Günther, Schirmacher, Peter, Plass, Christoph, Longerich, Thomas, Nordheim, Alfred
Publicado 2015

Genome-wide genetic and epigenetic analyses of pancreatic acinar cell carcinomas reveal aberrations in genome stability

por Jäkel, Cornelia, Bergmann, Frank, Toth, Reka, Assenov, Yassen, van der Duin, Daniel, Strobel, Oliver, Hank, Thomas, Klöppel, Günter, Dorrell, Craig, Grompe, Markus, Moss, Joshua, Dor, Yuval, Schirmacher, Peter, Plass, Christoph, Popanda, Odilia, Schmezer, Peter
Publicado 2017

The long non-coding RNA LINC00152 is essential for cell cycle progression through mitosis in HeLa cells

por Nötzold, Linda, Frank, Lukas, Gandhi, Minakshi, Polycarpou-Schwarz, Maria, Groß, Matthias, Gunkel, Manuel, Beil, Nina, Erfle, Holger, Harder, Nathalie, Rohr, Karl, Trendel, Jakob, Krijgsveld, Jeroen, Longerich, Thomas, Schirmacher, Peter, Boutros, Michael, Erhardt, Sylvia, Diederichs, Sven
Publicado 2017

Obesity as risk factor for subtypes of breast cancer: results from a prospective cohort study

por Nattenmüller, Cina J., Kriegsmann, Mark, Sookthai, Disorn, Fortner, Renée Turzanski, Steffen, Annika, Walter, Britta, Johnson, Theron, Kneisel, Jutta, Katzke, Verena, Bergmann, Manuela, Sinn, Hans Peter, Schirmacher, Peter, Herpel, Esther, Boeing, Heiner, Kaaks, Rudolf, Kühn, Tilman
Publicado 2018

Murine Liver Organoids as a Genetically Flexible System to Study Liver Cancer In Vivo and In Vitro

por Saborowski, Anna, Wolff, Katharina, Spielberg, Steffi, Beer, Benedikt, Hartleben, Björn, Erlangga, Zulrahman, Becker, Diana, Dow, Lukas E., Marhenke, Silke, Woller, Norman, Unger, Kristian, Schirmacher, Peter, Manns, Michael P., Marquardt, Jens U., Vogel, Arndt, Saborowski, Michael
Publicado 2019