Inflammatory responses in the placenta upon SARS-CoV-2 infection late in pregnancy

por Argueta, Lissenya B., Lacko, Lauretta A., Bram, Yaron, Tada, Takuya, Carrau, Lucia, Rendeiro, André Figueiredo, Zhang, Tuo, Uhl, Skyler, Lubor, Brienne C., Chandar, Vasuretha, Gil, Cristianel, Zhang, Wei, Dodson, Brittany J., Bastiaans, Jeroen, Prabhu, Malavika, Houghton, Sean, Redmond, David, Salvatore, Christine M., Yang, Yawei J., Elemento, Olivier, Baergen, Rebecca N., tenOever, Benjamin R., Landau, Nathaniel R., Chen, Shuibing, Schwartz, Robert E., Stuhlmann, Heidi
Publicado 2022

Modeling COVID-19 with Human Pluripotent Stem Cell-Derived Cells Reveals Synergistic Effects of Anti-inflammatory Macrophages with ACE2 Inhibition Against SARS-CoV-2

por Duan, Fuyu, Guo, Liyan, Yang, Liuliu, Han, Yuling, Thakur, Abhimanyu, Nilsson-Payant, Benjamin E., Wang, Pengfei, Zhang, Zhao, Yan Ma, Chui, Zhou, Xiaoya, Han, Teng, Zhang, Tuo, Wang, Xing, Xu, Dong, Duan, Xiaohua, Xiang, Jenny, Tse, Hung-fat, Liao, Can, Luo, Weiren, Huang, Fang-Ping, Chen, Ya-Wen, Evans, Todd, Schwartz, Robert E., tenOever, Benjamin, Ho, David D., Chen, Shuibing, Na, Jie, Lian, Qizhou, Chen, Huanhuan Joyce
Publicado 2020

Adaptable haemodynamic endothelial cells for organogenesis and tumorigenesis

por Palikuqi, Brisa, Nguyen, Duc-Huy T., Li, Ge, Schreiner, Ryan, Pellegata, Alessandro F., Liu, Ying, Redmond, David, Geng, Fuqiang, Lin, Yang, Gómez-Salinero, Jesus M., Yokoyama, Masataka, Zumbo, Paul, Zhang, Tuo, Kunar, Balvir, Witherspoon, Mavee, Han, Teng, Tedeschi, Alfonso M., Scottoni, Federico, Lipkin, Steven M., Dow, Lukas, Elemento, Olivier, Xiang, Jenny Z., Shido, Koji, Spence, Jason R., Zhou, Qiao J., Schwartz, Robert E., De Coppi, Paolo, Rabbany, Sina Y., Rafii, Shahin
Publicado 2020

SARS-CoV-2 Infection Causes Dopaminergic Neuron Senescence

por Han, Yuling, Yang, Liuliu, Kim, Tae Wan, Nair, Manoj S., Harschnitz, Oliver, Wang, Pengfei, Zhu, Jiajun, Koo, So Yeon, Tang, Xuming, Lacko, Lauretta A., Chandar, Vasuretha, Bram, Yaron, Zhang, Tuo, Zhang, Wei, He, Feng, Caicedo, James, Huang, Yaoxing, Evans, Todd, van der Valk, Paul, Titulaer, Maarten J., Spoor, Jochem K. H., Furler, Robert L., Canoll, Peter, Goldman, James E., Przedborski, Serge, Schwartz, Robert E., Ho, David D., Studer, Lorenz, Chen, Shuibing
Publicado 2021

Hyperglycemia in acute COVID-19 is characterized by insulin resistance and adipose tissue infectivity by SARS-CoV-2

por Reiterer, Moritz, Rajan, Mangala, Gómez-Banoy, Nicolás, Lau, Jennifer D., Gomez-Escobar, Luis G., Ma, Lunkun, Gilani, Ankit, Alvarez-Mulett, Sergio, Sholle, Evan T., Chandar, Vasuretha, Bram, Yaron, Hoffman, Katherine, Bhardwaj, Priya, Piloco, Phoebe, Rubio-Navarro, Alfonso, Uhl, Skyler, Carrau, Lucia, Houhgton, Sean, Redmond, David, Shukla, Alpana P., Goyal, Parag, Brown, Kristy A., tenOever, Benjamin R., Alonso, Laura C., Schwartz, Robert E., Schenck, Edward J., Safford, Monika M., Lo, James C.
Publicado 2021

Hyperglycemia in acute COVID-19 is characterized by insulin resistance and adipose tissue infectivity by SARS-CoV-2

por Reiterer, Moritz, Rajan, Mangala, Gómez-Banoy, Nicolás, Lau, Jennifer D., Gomez-Escobar, Luis G., Ma, Lunkun, Gilani, Ankit, Alvarez-Mulett, Sergio, Sholle, Evan T., Chandar, Vasuretha, Bram, Yaron, Hoffman, Katherine, Bhardwaj, Priya, Piloco, Phoebe, Rubio-Navarro, Alfonso, Uhl, Skyler, Carrau, Lucia, Houhgton, Sean, Redmond, David, Shukla, Alpana P., Goyal, Parag, Brown, Kristy A., tenOever, Benjamin R., Alonso, Laura C., Schwartz, Robert E., Schenck, Edward J., Safford, Monika M., Lo, James C.
Publicado 2021

Identification of SARS-CoV-2 Inhibitors using Lung and Colonic Organoids

por Han, Yuling, Duan, Xiaohua, Yang, Liuliu, Nilsson-Payant, Benjamin E., Wang, Pengfei, Duan, Fuyu, Tang, Xuming, Yaron, Tomer M., Zhang, Tuo, Uhl, Skyler, Bram, Yaron, Richardson, Chanel, Zhu, Jiajun, Zhao, Zeping, Redmond, David, Houghton, Sean, Nguyen, Duc-Huy T., Xu, Dong, Wang, Xing, Jessurun, Jose, Borczuk, Alain, Huang, Yaoxing, Johnson, Jared L., Liu, Yuru, Xiang, Jenny, Wang, Hui, Cantley, Lewis C., tenOever, Benjamin R., Ho, David D., Pan, Fong Cheng, Evans, Todd, Chen, Huanhuan Joyce, Schwartz, Robert E., Chen, Shuibing
Publicado 2020

A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and Organoids

por Yang, Liuliu, Han, Yuling, Nilsson-Payant, Benjamin E., Gupta, Vikas, Wang, Pengfei, Duan, Xiaohua, Tang, Xuming, Zhu, Jiajun, Zhao, Zeping, Jaffré, Fabrice, Zhang, Tuo, Kim, Tae Wan, Harschnitz, Oliver, Redmond, David, Houghton, Sean, Liu, Chengyang, Naji, Ali, Ciceri, Gabriele, Guttikonda, Sudha, Bram, Yaron, Nguyen, Duc-Huy T., Cioffi, Michele, Chandar, Vasuretha, Hoagland, Daisy A., Huang, Yaoxing, Xiang, Jenny, Wang, Hui, Lyden, David, Borczuk, Alain, Chen, Huanhuan Joyce, Studer, Lorenz, Pan, Fong Cheng, Ho, David D., tenOever, Benjamin R., Evans, Todd, Schwartz, Robert E., Chen, Shuibing
Publicado 2020

A human iPSC-array-based GWAS identifies a virus susceptibility locus in the NDUFA4 gene and functional variants

por Han, Yuling, Tan, Lei, Zhou, Ting, Yang, Liuliu, Carrau, Lucia, Lacko, Lauretta A., Saeed, Mohsan, Zhu, Jiajun, Zhao, Zeping, Nilsson-Payant, Benjamin E., Lira Neto, Filipe Tenorio, Cahir, Clare, Giani, Alice Maria, Chai, Jin Chou, Li, Yang, Dong, Xue, Moroziewicz, Dorota, Paull, Daniel, Zhang, Tuo, Koo, Soyeon, Tan, Christina, Danziger, Ron, Ba, Qian, Feng, Lingling, Chen, Zhengming, Zhong, Aaron, Wise, Gilbert J., Xiang, Jenny Z., Wang, Hui, Schwartz, Robert E., tenOever, Benjamin R., Noggle, Scott A., Rice, Charles M., Qi, Qibin, Evans, Todd, Chen, Shuibing
Publicado 2022

Author Correction: A molecular single-cell lung atlas of lethal COVID-19

por Melms, Johannes C., Biermann, Jana, Huang, Huachao, Wang, Yiping, Nair, Ajay, Tagore, Somnath, Katsyv, Igor, Rendeiro, André F., Amin, Amit Dipak, Schapiro, Denis, Frangieh, Chris J., Luoma, Adrienne M., Filliol, Aveline, Fang, Yinshan, Ravichandran, Hiranmayi, Clausi, Mariano G., Alba, George A., Rogava, Meri, Chen, Sean W., Ho, Patricia, Montoro, Daniel T., Kornberg, Adam E., Han, Arnold S., Bakhoum, Mathieu F., Anandasabapathy, Niroshana, Suárez-Fariñas, Mayte, Bakhoum, Samuel F., Bram, Yaron, Borczuk, Alain, Guo, Xinzheng V., Lefkowitch, Jay H., Marboe, Charles, Lagana, Stephen M., Del Portillo, Armando, Tsai, Emily J., Zorn, Emmanuel, Markowitz, Glen S., Schwabe, Robert F., Schwartz, Robert E., Elemento, Olivier, Saqi, Anjali, Hibshoosh, Hanina, Que, Jianwen, Izar, Benjamin
Publicado 2021

System-wide transcriptome damage and tissue identity loss in COVID-19 patients

por Park, Jiwoon, Foox, Jonathan, Hether, Tyler, Danko, David C., Warren, Sarah, Kim, Youngmi, Reeves, Jason, Butler, Daniel J., Mozsary, Christopher, Rosiene, Joel, Shaiber, Alon, Afshin, Evan E., MacKay, Matthew, Rendeiro, André F., Bram, Yaron, Chandar, Vasuretha, Geiger, Heather, Craney, Arryn, Velu, Priya, Melnick, Ari M., Hajirasouliha, Iman, Beheshti, Afshin, Taylor, Deanne, Saravia-Butler, Amanda, Singh, Urminder, Wurtele, Eve Syrkin, Schisler, Jonathan, Fennessey, Samantha, Corvelo, André, Zody, Michael C., Germer, Soren, Salvatore, Steven, Levy, Shawn, Wu, Shixiu, Tatonetti, Nicholas P., Shapira, Sagi, Salvatore, Mirella, Westblade, Lars F., Cushing, Melissa, Rennert, Hanna, Kriegel, Alison J., Elemento, Olivier, Imielinski, Marcin, Rice, Charles M., Borczuk, Alain C., Meydan, Cem, Schwartz, Robert E., Mason, Christopher E.
Publicado 2022

TARGETED DOWN REGULATION OF CORE MITOCHONDRIAL GENES DURING SARS-COV-2 INFECTION

por Guarnieri, Joseph W., Dybas, Joseph M., Fazelinia, Hossein, Kim, Man S., Frere, Justin, Zhang, Yuanchao, Albrecht, Yentli Soto, Murdock, Deborah G., Angelin, Alessia, Singh, Larry N., Weiss, Scott L., Best, Sonja M., Lott, Marie T., Cope, Henry, Zaksas, Viktorija, Saravia-Butler, Amanda, Meydan, Cem, Foox, Jonathan, Mozsary, Christopher, Kidane, Yared H., Priebe, Waldemar, Emmett, Mark R., Meller, Robert, Singh, Urminder, Bram, Yaron, tenOever, Benjamin R., Heise, Mark T., Moorman, Nathaniel J., Madden, Emily A., Taft-Benz, Sharon A., Anderson, Elizabeth J., Sanders, Wes A., Dickmander, Rebekah J., Baxter, Victoria K., Baylin, Stephen B., Wurtele, Eve Syrkin, Moraes-Vieira, Pedro M., Taylor, Deanne, Mason, Christopher E., Schisler, Jonathan C., Schwartz, Robert E., Beheshti, Afshin, Wallace, Douglas C.
Publicado 2022

Intestinal Host Response to SARS-CoV-2 Infection and COVID-19 Outcomes in Patients With Gastrointestinal Symptoms

por Livanos, Alexandra E., Jha, Divya, Cossarini, Francesca, Gonzalez-Reiche, Ana S., Tokuyama, Minami, Aydillo, Teresa, Parigi, Tommaso L., Ladinsky, Mark S., Ramos, Irene, Dunleavy, Katie, Lee, Brian, Dixon, Rebekah E., Chen, Steven T., Martinez-Delgado, Gustavo, Nagula, Satish, Bruce, Emily A., Ko, Huaibin M., Glicksberg, Benjamin S., Nadkarni, Girish, Pujadas, Elisabet, Reidy, Jason, Naymagon, Steven, Grinspan, Ari, Ahmad, Jawad, Tankelevich, Michael, Bram, Yaron, Gordon, Ronald, Sharma, Keshav, Houldsworth, Jane, Britton, Graham J., Chen-Liaw, Alice, Spindler, Matthew P., Plitt, Tamar, Wang, Pei, Cerutti, Andrea, Faith, Jeremiah J., Colombel, Jean-Frederic, Kenigsberg, Ephraim, Argmann, Carmen, Merad, Miriam, Gnjatic, Sacha, Harpaz, Noam, Danese, Silvio, Cordon-Cardo, Carlos, Rahman, Adeeb, Schwartz, Robert E., Kumta, Nikhil A., Aghemo, Alessio, Bjorkman, Pamela J., Petralia, Francesca, van Bakel, Harm, Garcia-Sastre, Adolfo, Mehandru, Saurabh
Publicado 2021

Host protein kinases required for SARS-CoV-2 nucleocapsid phosphorylation and viral replication

por Yaron, Tomer M., Heaton, Brook E., Levy, Tyler M., Johnson, Jared L., Jordan, Tristan X., Cohen, Benjamin M., Kerelsky, Alexander, Lin, Ting-Yu, Liberatore, Katarina M., Bulaon, Danielle K., Van Nest, Samantha J., Koundouros, Nikos, Kastenhuber, Edward R., Mercadante, Marisa N., Shobana-Ganesh, Kripa, He, Long, Schwartz, Robert E., Chen, Shuibing, Weinstein, Harel, Elemento, Olivier, Piskounova, Elena, Nilsson-Payant, Benjamin E., Lee, Gina, Trimarco, Joseph D., Burke, Kaitlyn N., Hamele, Cait E., Chaparian, Ryan R., Harding, Alfred T., Tata, Aleksandra, Zhu, Xinyu, Tata, Purushothama Rao, Smith, Clare M., Possemato, Anthony P., Tkachev, Sasha L., Hornbeck, Peter V., Beausoleil, Sean A., Anand, Shankara K., Aguet, François, Getz, Gad, Davidson, Andrew D., Heesom, Kate, Kavanagh-Williamson, Maia, Matthews, David A., tenOever, Benjamin R., Cantley, Lewis C., Blenis, John, Heaton, Nicholas S.
Publicado 2022

Shotgun transcriptome, spatial omics, and isothermal profiling of SARS-CoV-2 infection reveals unique host responses, viral diversification, and drug interactions

por Butler, Daniel, Mozsary, Christopher, Meydan, Cem, Foox, Jonathan, Rosiene, Joel, Shaiber, Alon, Danko, David, Afshinnekoo, Ebrahim, MacKay, Matthew, Sedlazeck, Fritz J., Ivanov, Nikolay A., Sierra, Maria, Pohle, Diana, Zietz, Michael, Gisladottir, Undina, Ramlall, Vijendra, Sholle, Evan T., Schenck, Edward J., Westover, Craig D., Hassan, Ciaran, Ryon, Krista, Young, Benjamin, Bhattacharya, Chandrima, Ng, Dianna L., Granados, Andrea C., Santos, Yale A., Servellita, Venice, Federman, Scot, Ruggiero, Phyllis, Fungtammasan, Arkarachai, Chin, Chen-Shan, Pearson, Nathaniel M., Langhorst, Bradley W., Tanner, Nathan A., Kim, Youngmi, Reeves, Jason W., Hether, Tyler D., Warren, Sarah E., Bailey, Michael, Gawrys, Justyna, Meleshko, Dmitry, Xu, Dong, Couto-Rodriguez, Mara, Nagy-Szakal, Dorottya, Barrows, Joseph, Wells, Heather, O’Hara, Niamh B., Rosenfeld, Jeffrey A., Chen, Ying, Steel, Peter A. D., Shemesh, Amos J., Xiang, Jenny, Thierry-Mieg, Jean, Thierry-Mieg, Danielle, Iftner, Angelika, Bezdan, Daniela, Sanchez, Elizabeth, Campion, Thomas R., Sipley, John, Cong, Lin, Craney, Arryn, Velu, Priya, Melnick, Ari M., Shapira, Sagi, Hajirasouliha, Iman, Borczuk, Alain, Iftner, Thomas, Salvatore, Mirella, Loda, Massimo, Westblade, Lars F., Cushing, Melissa, Wu, Shixiu, Levy, Shawn, Chiu, Charles, Schwartz, Robert E., Tatonetti, Nicholas, Rennert, Hanna, Imielinski, Marcin, Mason, Christopher E.
Publicado 2021