PDCD1 Polymorphisms May Predict Response to Anti-PD-1 Blockade in Patients With Metastatic Melanoma

por Parakh, Sagun, Musafer, Ashan, Paessler, Sabrina, Witkowski, Tom, Suen, Connie S. N. Li Wai, Tutuka, Candani S. A., Carlino, Matteo S., Menzies, Alexander M., Scolyer, Richard A., Cebon, Jonathan, Dobrovic, Alexander, Long, Georgina V., Klein, Oliver, Behren, Andreas
Publicado 2021

Diagnostic Accuracy of Fine Needle Biopsy for Metastatic Melanoma and Its Implications for Patient Management

por Doubrovsky, Anna, Scolyer, Richard A., Murali, Rajmohan, McKenzie, Paul R., Watson, Geoffrey F., Lee, C. Soon, McLeod, Duncan J., McCarthy, William H., Uren, Roger F., Stretch, Jonathan R., Saw, Robyn P., Thompson, John F.
Publicado 2007

A highly recurrent RPS27 5'UTR mutation in melanoma

por Dutton-Regester, Ken, Gartner, Jared J., Emmanuel, Rafi, Qutob, Nouar, Davies, Michael A., Gershenwald, Jeffrey E., Robinson, William, Robinson, Steven, Rosenberg, Steven A., Scolyer, Richard A., Mann, Graham J., Thompson, John F., Hayward, Nicholas K., Samuels, Yardena
Publicado 2014

Pretreatment Innate Cell Populations and CD4 T Cells in Blood Are Associated With Response to Immune Checkpoint Blockade in Melanoma Patients

por Pirozyan, Mehdi R., McGuire, Helen M., Emran, Abdullah Al, Tseng, Hsin-Yi, Tiffen, Jessamy C., Lee, Jenny H., Carlino, Matteo S., Menzies, Alexander M., Long, Georgina V., Scolyer, Richard A., Fazekas de St Groth, Barbara, Hersey, Peter
Publicado 2020

Detailed spatial immunophenotyping of primary melanomas reveals immune cell subpopulations associated with patient outcome

por Attrill, Grace H., Lee, Hansol, Tasker, Annie T., Adegoke, Nurudeen A., Ferguson, Angela L., da Silva, Ines Pires, Saw, Robyn P. M., Thompson, John F., Palendira, Umaimainthan, Long, Georgina V., Ferguson, Peter M., Scolyer, Richard A., Wilmott, James S.
Publicado 2022

Epigenetic Changes of EGFR play an important role in BRAF inhibitor Resistant Cutaneous Melanomas

por Wang, Jinhua, Huang, Sharon K., Marzese, Diego M., Hsu, Sandy C., Kawas, Neal P., Chong, Kelly K., Long, Georgina V., Menzies, Alexander M., Scolyer, Richard A., Izraely, Sivan, Sagi-Assif, Orit, Witz, Isaac P., Hoon, Dave S.B.
Publicado 2014

First interim analysis of a randomised trial of whole brain radiotherapy in melanoma brain metastases confirms high data quality

por Fogarty, Gerald B, Hong, Angela, Dolven-Jacobsen, Kari, Reisse, Claudius H, Burmeister, Bryan, Haydu, Lauren H, Dhillon, Haryana, Steel, Victoria, Shivalingam, Brindha, Drummond, Kate, Vardy, Janette, Nowak, Anna, Hruby, George, Scolyer, Richard A, Mandel, Catherine, Thompson, John F
Publicado 2015

Tumor MHC Expression Guides First-Line Immunotherapy Selection in Melanoma

por Shklovskaya, Elena, Lee, Jenny H, Lim, Su Yin, Stewart, Ashleigh, Pedersen, Bernadette, Ferguson, Peter, Saw, Robyn PM, Thompson, John F, Shivalingam, Brindha, Carlino, Matteo S, Scolyer, Richard A, Menzies, Alexander M, Long, Georgina V, Kefford, Richard F, Rizos, Helen
Publicado 2020

Clinical and Molecular Heterogeneity in Patients with Innate Resistance to Anti-PD-1 +/− Anti-CTLA-4 Immunotherapy in Metastatic Melanoma Reveals Distinct Therapeutic Targets

por Gide, Tuba N., Pires da Silva, Inês, Quek, Camelia, Ferguson, Peter M., Batten, Marcel, Shang, Ping, Ahmed, Tasnia, Menzies, Alexander M., Carlino, Matteo S., Saw, Robyn P. M., Thompson, John F., Scolyer, Richard A., Long, Georgina V., Wilmott, James S.
Publicado 2021

SIRT6 haploinsufficiency induces BRAF(V600E) melanoma cell resistance to MAPK inhibitors via IGF signalling

por Strub, Thomas, Ghiraldini, Flavia G., Carcamo, Saul, Li, Man, Wroblewska, Aleksandra, Singh, Rajendra, Goldberg, Matthew S., Hasson, Dan, Wang, Zichen, Gallagher, Stuart J., Hersey, Peter, Ma’ayan, Avi, Long, Georgina V., Scolyer, Richard A., Brown, Brian, Zheng, Bin, Bernstein, Emily
Publicado 2018

Replacement and desmoplastic histopathological growth patterns in cutaneous melanoma liver metastases: frequency, characteristics, and robust prognostic value

por Barnhill, Raymond, van Dam, Pieter‐Jan, Vermeulen, Peter, Champenois, Gabriel, Nicolas, André, Rawson, Robert V, Wilmott, James S, Thompson, John F, Long, Georgina V, Cassoux, Nathalie, Roman‐Roman, Sergio, Busam, Klaus J, Scolyer, Richard A, Lazar, Alexander J, Lugassy, Claire
Publicado 2020

Melanoma whole exome sequencing identifies (V600E)B-RAF amplification-mediated acquired B-RAF inhibitor resistance

por Shi, Hubing, Moriceau, Gatien, Kong, Xiangju, Lee, Mi-Kyung, Lee, Hane, Koya, Richard C., Ng, Charles, Chodon, Thinle, Scolyer, Richard A., Dahlman, Kimberly B., Sosman, Jeffrey A., Kefford, Richard F., Long, Georgina V., Nelson, Stanley F., Ribas, Antoni, Lo, Roger S.
Publicado 2012

INPP4B is upregulated and functions as an oncogenic driver through SGK3 in a subset of melanomas

por Chi, Meng Na, Guo, Su Tang, Wilmott, James S., Guo, Xiang Yun, Yan, Xu Guang, Wang, Chun Yan, Liu, Xiao Ying, Jin, Lei, Tseng, Hsin-Yi, Liu, Tao, Croft, Amanda, Hondermarck, Hubert, Scolyer, Richard A., Jiang, Chen Chen, Zhang, Xu Dong
Publicado 2015

Characterization of the treatment-naive immune microenvironment in melanoma with BRAF mutation

por Wang, Minyu, Zadeh, Soroor, Pizzolla, Angela, Thia, Kevin, Gyorki, David E, McArthur, Grant A, Scolyer, Richard A, Long, Georgina, Wilmott, James S, Andrews, Miles C, Au-Yeung, George, Weppler, Ali, Sandhu, Shahneen, Trapani, Joseph A, Davis, Melissa J, Neeson, Paul Joseph
Publicado 2022

Improving Selection for Sentinel Lymph Node Biopsy Among Patients With Melanoma

por Miller, James R., Lo, Serigne N., Nosrati, Mehdi, Stretch, Jonathan R., Spillane, Andrew J., Saw, Robyn P. M., Shannon, Kerwin F., Nieweg, Omgo E., Ch’ng, Sydney, Kim, Kevin B., Leong, Stanley P., Thompson, John F., Scolyer, Richard A., Kashani-Sabet, Mohammed
Publicado 2023

Targeting the MAPK and PI3K pathways in combination with PD1 blockade in melanoma

por Deken, Marcel A., Gadiot, Jules, Jordanova, Ekaterina S., Lacroix, Ruben, van Gool, Melissa, Kroon, Paula, Pineda, Cristina, Geukes Foppen, Marnix H., Scolyer, Richard, Song, Ji-Ying, Verbrugge, Inge, Hoeller, Christoph, Dummer, Reinhard, Haanen, John B. A. G., Long, Georgina V., Blank, Christian U.
Publicado 2016

The mutational landscape of melanoma brain metastases presenting as the first visceral site of recurrence

por Rabbie, Roy, Ferguson, Peter, Wong, Kim, Couturier, Dominique-Laurent, Moran, Una, Turner, Clinton, Emanuel, Patrick, Haas, Kerstin, Saunus, Jodi M., Davidson, Morgan R., Lakhani, Sunil R., Shivalingam, Brindha, Long, Georgina V., Parkinson, Christine, Osman, Iman, Scolyer, Richard A., Corrie, Pippa, Adams, David J.
Publicado 2020

Road to Metastasis: The TWEAK Pathway as a Discriminant between Metastasizing and Non-Metastasizing Thick Melanomas

por Güvenç, Canan, Antoranz, Asier, Szumera-Ciećkiewicz, Anna, Teterycz, Pawel P., Rutkowski, Piotr R., Rawson, Robert V., Scolyer, Richard A., Thompson, John F., Newton-Bishop, Julia, Stas, Marguerite, Boecxstaens, Veerle, Bechter, Oliver, Vercauteren, Jurgen, Garmyn, Marjan, van den Oord, Joost, Bosisio, Francesca Maria
Publicado 2021

TRIM16 inhibits proliferation and migration through regulation of interferon beta 1 in melanoma cells

por Sutton, Selina K., Koach, Jessica, Tan, Owen, Liu, Bing, Carter, Daniel R., Wilmott, James S., Yosufi, Benafsha, Haydu, Lauren E., Mann, Graham J., Thompson, John F., Long, Georgina V., Liu, Tao, McArthur, Grant, Zhang, Xu Dong, Scolyer, Richard A., Cheung, Belamy B., Marshall, Glenn M.
Publicado 2014

Analysis of the Whole-Exome Sequencing of Tumor and Circulating Tumor DNA in Metastatic Melanoma

por Diefenbach, Russell J., Lee, Jenny H., Strbenac, Dario, Yang, Jean Y. H., Menzies, Alexander M., Carlino, Matteo S., Long, Georgina V., Spillane, Andrew J., Stretch, Jonathan R., Saw, Robyn P. M., Thompson, John F., Ch’ng, Sydney, Scolyer, Richard A., Kefford, Richard F., Rizos, Helen
Publicado 2019