Sequential Exposure to Obesogenic Factors in Females Rats: From Physiological Changes to Lipid Metabolism in Liver and Mesenteric Adipose Tissue

por Novelle, Marta G., Vázquez, María J., Peinado, Juan R., Martinello, Kátia D., López, Miguel, Luckman, Simon M., Tena-Sempere, Manuel, Malagón, María M., Nogueiras, Rubén, Diéguez, Carlos
Publicado 2017

Beyond the brain-Peripheral kisspeptin signaling is essential for promoting endometrial gland development and function

por León, Silvia, Fernadois, Daniela, Sull, Alexandra, Sull, Judith, Calder, Michele, Hayashi, Kanako, Bhattacharya, Moshmi, Power, Stephen, Vilos, George A., Vilos, Angelos G., Tena-Sempere, Manuel, Babwah, Andy V.
Publicado 2016

Corrigendum: Beyond the brain-Peripheral kisspeptin signaling is essential for promoting endometrial gland development and function

por León, Silvia, Fernandois, Daniela, Sull, Alexandra, Sull, Judith, Calder, Michele, Hayashi, Kanako, Bhattacharya, Moshmi, Power, Stephen, Vilos, George A., Vilos, Angelos G., Tena-Sempere, Manuel, Babwah, Andy V.
Publicado 2016

A Functional Link between AMPK and Orexin Mediates the Effect of BMP8B on Energy Balance

por Martins, Luís, Seoane-Collazo, Patricia, Contreras, Cristina, González-García, Ismael, Martínez-Sánchez, Noelia, González, Francisco, Zalvide, Juan, Gallego, Rosalía, Diéguez, Carlos, Nogueiras, Rubén, Tena-Sempere, Manuel, López, Miguel
Publicado 2016

mTOR signaling in the arcuate nucleus of the hypothalamus mediates the anorectic action of estradiol

por González-García, Ismael, Martínez de Morentin, Pablo B, Estévez-Salguero, Ánxela, Contreras, Cristina, Romero-Picó, Amparo, Fernø, Johan, Nogueiras, Rubén, Diéguez, Carlos, Tena-Sempere, Manuel, Tovar, Sulay, López, Miguel
Publicado 2018

Selective loss of kisspeptin signaling in oocytes causes progressive premature ovulatory failure

por Ruohonen, Suvi T, Gaytan, Francisco, Usseglio Gaudi, Andrea, Velasco, Inmaculada, Kukoricza, Krisztina, Perdices-Lopez, Cecilia, Franssen, Delphine, Guler, Ipek, Mehmood, Arfa, Elo, Laura L, Ohlsson, Claes, Poutanen, Matti, Tena-Sempere, Manuel
Publicado 2022

Kappa-Opioid Receptor Blockade Ameliorates Obesity Caused by Estrogen Withdrawal via Promotion of Energy Expenditure through mTOR Pathway

por Romero-Picó, Amparo, Novelle, Marta G., Al-Massadi, Omar, Beiroa, Daniel, Tojo, Marta, Heras, Violeta, Ruiz-Pino, Francisco, Senra, Ana, López, Miguel, Blouet, Clemence, Tena-Sempere, Manuel, Nogueiras, Rubén, Diéguez, Carlos
Publicado 2022

Direct Actions of Kisspeptins on GnRH Neurons Permit Attainment of Fertility but are Insufficient to Fully Preserve Gonadotropic Axis Activity

por León, Silvia, Barroso, Alexia, Vázquez, María J., García-Galiano, David, Manfredi-Lozano, María, Ruiz-Pino, Francisco, Heras, Violeta, Romero-Ruiz, Antonio, Roa, Juan, Schutz, Günther, Kirilov, Milen, Gaytan, Francisco, Pinilla, Leonor, Tena-Sempere, Manuel
Publicado 2016

VCE-004.8, A Multitarget Cannabinoquinone, Attenuates Adipogenesis and Prevents Diet-Induced Obesity

por Palomares, Belen, Ruiz-Pino, Francisco, Navarrete, Carmen, Velasco, Inmaculada, Sánchez-Garrido, Miguel A., Jimenez-Jimenez, Carla, Pavicic, Carolina, Vazquez, Maria J., Appendino, Giovanni, Bellido, M. Luz, Calzado, Marco A., Tena-Sempere, Manuel, Muñoz, Eduardo
Publicado 2018

The Lin28/Let-7 System in Early Human Embryonic Tissue and Ectopic Pregnancy

por Lozoya, Teresa, Domínguez, Francisco, Romero-Ruiz, Antonio, Steffani, Liliana, Martínez, Sebastián, Monterde, Mercedes, Ferri, Blanca, Núñez, Maria Jose, AinhoaRomero-Espinós, Zamora, Omar, Gurrea, Marta, Sangiao-Alvarellos, Susana, Vega, Olivia, Simón, Carlos, Pellicer, Antonio, Tena-Sempere, Manuel
Publicado 2014

Defining a novel leptin–melanocortin–kisspeptin pathway involved in the metabolic control of puberty

por Manfredi-Lozano, Maria, Roa, Juan, Ruiz-Pino, Francisco, Piet, Richard, Garcia-Galiano, David, Pineda, Rafael, Zamora, Aurora, Leon, Silvia, Sanchez-Garrido, Miguel A., Romero-Ruiz, Antonio, Dieguez, Carlos, Vazquez, Maria Jesus, Herbison, Allan E., Pinilla, Leonor, Tena-Sempere, Manuel
Publicado 2016

Interplay between gonadal hormones and postnatal overfeeding in defining sex-dependent differences in gut microbiota architecture

por Santos-Marcos, Jose A., Barroso, Alexia, Rangel-Zuñiga, Oriol A., Perdices-Lopez, Cecilia, Haro, Carmen, Sanchez-Garrido, Miguel A., Molina-Abril, Helena, Ohlsson, Claes, Perez-Martinez, Pablo, Poutanen, Matti, Lopez-Miranda, Jose, Perez-Jimenez, Francisco, Tena-Sempere, Manuel, Camargo, Antonio
Publicado 2020

Estradiol Regulates Energy Balance by Ameliorating Hypothalamic Ceramide-Induced ER Stress

por González-García, Ismael, Contreras, Cristina, Estévez-Salguero, Ánxela, Ruíz-Pino, Francisco, Colsh, Benoit, Pensado, Iván, Liñares-Pose, Laura, Rial-Pensado, Eva, Martínez de Morentin, Pablo B., Fernø, Johan, Diéguez, Carlos, Nogueiras, Rubén, Le Stunff, Hervé, Magnan, Christophe, Tena-Sempere, Manuel, López, Miguel
Publicado 2018

Intestinal Microbiota Is Influenced by Gender and Body Mass Index

por Haro, Carmen, Rangel-Zúñiga, Oriol A., Alcalá-Díaz, Juan F., Gómez-Delgado, Francisco, Pérez-Martínez, Pablo, Delgado-Lista, Javier, Quintana-Navarro, Gracia M., Landa, Blanca B., Navas-Cortés, Juan A., Tena-Sempere, Manuel, Clemente, José C., López-Miranda, José, Pérez-Jiménez, Francisco, Camargo, Antonio
Publicado 2016

Dicer ablation in Kiss1 neurons impairs puberty and fertility preferentially in female mice

por Roa, Juan, Ruiz-Cruz, Miguel, Ruiz-Pino, Francisco, Onieva, Rocio, Vazquez, Maria J., Sanchez-Tapia, Maria J., Ruiz-Rodriguez, Jose M., Sobrino, Veronica, Barroso, Alexia, Heras, Violeta, Velasco, Inmaculada, Perdices-Lopez, Cecilia, Ohlsson, Claes, Avendaño, Maria Soledad, Prevot, Vincent, Poutanen, Matti, Pinilla, Leonor, Gaytan, Francisco, Tena-Sempere, Manuel
Publicado 2022

Estradiol Regulates Brown Adipose Tissue Thermogenesis via Hypothalamic AMPK

por Martínez de Morentin, Pablo B., González-García, Ismael, Martins, Luís, Lage, Ricardo, Fernández-Mallo, Diana, Martínez-Sánchez, Noelia, Ruíz-Pino, Francisco, Liu, Ji, Morgan, Donald A., Pinilla, Leonor, Gallego, Rosalía, Saha, Asish K., Kalsbeek, Andries, Fliers, Eric, Bisschop, Peter H., Diéguez, Carlos, Nogueiras, Rubén, Rahmouni, Kamal, Tena-Sempere, Manuel, López, Miguel
Publicado 2014

Hypothalamic miR-30 regulates puberty onset via repression of the puberty-suppressing factor, Mkrn3

por Heras, Violeta, Sangiao-Alvarellos, Susana, Manfredi-Lozano, Maria, Sanchez-Tapia, María J., Ruiz-Pino, Francisco, Roa, Juan, Lara-Chica, Maribel, Morrugares-Carmona, Rosario, Jouy, Nathalie, Abreu, Ana P., Prevot, Vincent, Belsham, Denise, Vazquez, Maria J., Calzado, Marco A., Pinilla, Leonor, Gaytan, Francisco, Latronico, Ana C., Kaiser, Ursula B., Castellano, Juan M., Tena-Sempere, Manuel
Publicado 2019

Metformin and simvastatin exert additive antitumour effects in glioblastoma via senescence-state: clinical and translational evidence

por Fuentes-Fayos, Antonio C., G-García, Miguel E., Pérez-Gómez, Jesús M., Montero-Hidalgo, Antonio J., Martín-Colom, Julia, Doval-Rosa, Carlos, Blanco-Acevedo, Cristóbal, Torres, Encarnación, Toledano-Delgado, Álvaro, Sánchez-Sánchez, Rafael, Peralbo-Santaella, Esther, Ortega-Salas, Rosa M., Jiménez-Vacas, Juan M., Tena-Sempere, Manuel, López, Miguel, Castaño, Justo P., Gahete, Manuel D., Solivera, Juan, Luque, Raúl M.
Publicado 2023

KLB, encoding β‐Klotho, is mutated in patients with congenital hypogonadotropic hypogonadism

por Xu, Cheng, Messina, Andrea, Somm, Emmanuel, Miraoui, Hichem, Kinnunen, Tarja, Acierno, James, Niederländer, Nicolas J, Bouilly, Justine, Dwyer, Andrew A, Sidis, Yisrael, Cassatella, Daniele, Sykiotis, Gerasimos P, Quinton, Richard, De Geyter, Christian, Dirlewanger, Mirjam, Schwitzgebel, Valérie, Cole, Trevor R, Toogood, Andrew A, Kirk, Jeremy MW, Plummer, Lacey, Albrecht, Urs, Crowley, William F, Mohammadi, Moosa, Tena‐Sempere, Manuel, Prevot, Vincent, Pitteloud, Nelly
Publicado 2017

Two missense mutations in KCNQ1 cause pituitary hormone deficiency and maternally inherited gingival fibromatosis

por Tommiska, Johanna, Känsäkoski, Johanna, Skibsbye, Lasse, Vaaralahti, Kirsi, Liu, Xiaonan, Lodge, Emily J., Tang, Chuyi, Yuan, Lei, Fagerholm, Rainer, Kanters, Jørgen K., Lahermo, Päivi, Kaunisto, Mari, Keski-Filppula, Riikka, Vuoristo, Sanna, Pulli, Kristiina, Ebeling, Tapani, Valanne, Leena, Sankila, Eeva-Marja, Kivirikko, Sirpa, Lääperi, Mitja, Casoni, Filippo, Giacobini, Paolo, Phan-Hug, Franziska, Buki, Tal, Tena-Sempere, Manuel, Pitteloud, Nelly, Veijola, Riitta, Lipsanen-Nyman, Marita, Kaunisto, Kari, Mollard, Patrice, Andoniadou, Cynthia L., Hirsch, Joel A., Varjosalo, Markku, Jespersen, Thomas, Raivio, Taneli
Publicado 2017