CMV seropositivity and T‐cell senescence predict increased cardiovascular mortality in octogenarians: results from the Newcastle 85+ study

por Spyridopoulos, Ioakim, Martin‐Ruiz, Carmen, Hilkens, Catharien, Yadegarfar, Mohammad E., Isaacs, John, Jagger, Carol, Kirkwood, Tom, von Zglinicki, Thomas
Publicado 2015

Grip strength and inflammatory biomarker profiles in very old adults

por Granic, Antoneta, Davies, Karen, Martin-Ruiz, Carmen, Jagger, Carol, Kirkwood, Thomas B L, von Zglinicki, Thomas, Aihie Sayer, Avan
Publicado 2017

Dynamic Modelling of Pathways to Cellular Senescence Reveals Strategies for Targeted Interventions

por Dalle Pezze, Piero, Nelson, Glyn, Otten, Elsje G., Korolchuk, Viktor I., Kirkwood, Thomas B. L., von Zglinicki, Thomas, Shanley, Daryl P.
Publicado 2014

Inflammation, But Not Telomere Length, Predicts Successful Ageing at Extreme Old Age: A Longitudinal Study of Semi-supercentenarians

por Arai, Yasumichi, Martin-Ruiz, Carmen M., Takayama, Michiyo, Abe, Yukiko, Takebayashi, Toru, Koyasu, Shigeo, Suematsu, Makoto, Hirose, Nobuyoshi, von Zglinicki, Thomas
Publicado 2015

The Newcastle 85+ study: biological, clinical and psychosocial factors associated with healthy ageing: study protocol

por Collerton, Joanna, Barrass, Karen, Bond, John, Eccles, Martin, Jagger, Carol, James, Oliver, Martin-Ruiz, Carmen, Robinson, Louise, von Zglinicki, Thomas, Kirkwood, Tom
Publicado 2007

Fat tissue, aging, and cellular senescence

por Tchkonia, Tamara, Morbeck, Dean E, von Zglinicki, Thomas, van Deursen, Jan, Lustgarten, Joseph, Scrable, Heidi, Khosla, Sundeep, Jensen, Michael D, Kirkland, James L
Publicado 2010

Adult-onset, short-term dietary restriction reduces cell senescence in mice

por Wang, Chunfang, Maddick, Mandy, Miwa, Satomi, Jurk, Diana, Czapiewski, Rafal, Saretzki, Gabriele, Langie, Sabine A.S., Godschalk, Roger W.L., Cameron, Kerry, von Zglinicki, Thomas
Publicado 2010

High-Throughput 13-Parameter Immunophenotyping Identifies Shifts in the Circulating T-Cell Compartment Following Reperfusion in Patients with Acute Myocardial Infarction

por Hoffmann, Jedrzej, Fiser, Karel, Weaver, Jolanta, Dimmick, Ian, Loeher, Monika, Pircher, Hanspeter, Martin-Ruiz, Carmen, Veerasamy, Murugapathy, Keavney, Bernard, von Zglinicki, Thomas, Spyridopoulos, Ioakim
Publicado 2012

Postmitotic neurons develop a p21-dependent senescence-like phenotype driven by a DNA damage response

por Jurk, Diana, Wang, Chunfang, Miwa, Satomi, Maddick, Mandy, Korolchuk, Viktor, Tsolou, Avgi, Gonos, Efstathios S, Thrasivoulou, Christopher, Jill Saffrey, M, Cameron, Kerry, von Zglinicki, Thomas
Publicado 2012

Anti‐inflammatory treatment rescues memory deficits during aging in nfkb1 (−/−) mice

por Fielder, Edward, Tweedy, Clare, Wilson, Caroline, Oakley, Fiona, LeBeau, Fiona E. N., Passos, João F., Mann, Derek A., von Zglinicki, Thomas, Jurk, Diana
Publicado 2020

Nucleoplasmic LAP2α–lamin A complexes are required to maintain a proliferative state in human fibroblasts

por Pekovic, Vanja, Harborth, Jens, Broers, Jos L.V., Ramaekers, Frans C.S., van Engelen, Baziel, Lammens, Martin, von Zglinicki, Thomas, Foisner, Roland, Hutchison, Chris, Markiewicz, Ewa
Publicado 2007

Shared Ageing Research Models (ShARM): a new facility to support ageing research

por Duran, Adele L., Potter, Paul, Wells, Sara, Kirkwood, Tom, von Zglinicki, Thomas, McArdle, Anne, Scudamore, Cheryl, Meng, Qing-Jun, de Haan, Gerald, Corcoran, Anne, Bellantuono, Ilaria
Publicado 2013

Frailty and mortality are not influenced by mitochondrial DNA haplotypes in the very old()

por Collerton, Joanna, Ashok, Deepthi, Martin-Ruiz, Carmen, Pyle, Angela, Hudson, Gavin, Yadegarfar, Mohammad, Davies, Karen, Jagger, Carol, von Zglinicki, Thomas, Kirkwood, Thomas B.L., Chinnery, Patrick F.
Publicado 2013

The epigenetic clock and telomere length are independently associated with chronological age and mortality

por Marioni, Riccardo E, Harris, Sarah E, Shah, Sonia, McRae, Allan F, von Zglinicki, Thomas, Martin-Ruiz, Carmen, Wray, Naomi R, Visscher, Peter M, Deary, Ian J
Publicado 2016

The epigenetic clock and telomere length are independently associated with chronological age and mortality

por Marioni, Riccardo E, Harris, Sarah E, Shah, Sonia, McRae, Allan F, von Zglinicki, Thomas, Martin-Ruiz, Carmen, Wray, Naomi R, Visscher, Peter M, Deary, Ian J
Publicado 2018

The bystander effect contributes to the accumulation of senescent cells in vivo

por da Silva, Paulo F. L., Ogrodnik, Mikolaj, Kucheryavenko, Olena, Glibert, Julien, Miwa, Satomi, Cameron, Kerry, Ishaq, Abbas, Saretzki, Gabriele, Nagaraja‐Grellscheid, Sushma, Nelson, Glyn, von Zglinicki, Thomas
Publicado 2018

Longitudinal telomere length shortening and cognitive and physical decline in later life: The Lothian Birth Cohorts 1936 and 1921

por Harris, Sarah E., Marioni, Riccardo E., Martin-Ruiz, Carmen, Pattie, Alison, Gow, Alan J., Cox, Simon R., Corley, Janie, von Zglinicki, Thomas, Starr, John M., Deary, Ian J.
Publicado 2016

Capability and dependency in the Newcastle 85+ cohort study. Projections of future care needs

por Jagger, Carol, Collerton, Joanna C, Davies, Karen, Kingston, Andrew, Robinson, Louise A, Eccles, Martin P, von Zglinicki, Thomas, Martin-Ruiz, Carmen, James, Oliver FW, Kirkwood, Tom BL, Bond, John
Publicado 2011

Rate of telomere shortening and cardiovascular damage: a longitudinal study in the 1946 British Birth Cohort

por Masi, Stefano, D'Aiuto, Francesco, Martin-Ruiz, Carmen, Kahn, Tauseef, Wong, Andrew, Ghosh, Arjun K., Whincup, Peter, Kuh, Diana, Hughes, Alan, von Zglinicki, Thomas, Hardy, Rebecca, Deanfield, John Eric
Publicado 2014

Short senolytic or senostatic interventions rescue progression of radiation-induced frailty and premature ageing in mice

por Fielder, Edward, Wan, Tengfei, Alimohammadiha, Ghazaleh, Ishaq, Abbas, Low, Evon, Weigand, B Melanie, Kelly, George, Parker, Craig, Griffin, Brigid, Jurk, Diana, Korolchuk, Viktor I, von Zglinicki, Thomas, Miwa, Satomi
Publicado 2022