The Epigenetic Regulatory Protein CBX2 Promotes mTORC1 Signalling and Inhibits DREAM Complex Activity to Drive Breast Cancer Cell Growth

por Bilton, Lucie J., Warren, Chloe, Humphries, Rebecca M., Kalsi, Shannon, Waters, Ella, Francis, Thomas, Dobrowinski, Wojtek, Beltran-Alvarez, Pedro, Wade, Mark A.
Publicado 2022

Growth faltering is associated with altered brain functional connectivity and cognitive outcomes in urban Bangladeshi children exposed to early adversity

por Xie, Wanze, Jensen, Sarah K. G., Wade, Mark, Kumar, Swapna, Westerlund, Alissa, Kakon, Shahria H., Haque, Rashidul, Petri, William A., Nelson, Charles A.
Publicado 2019

KDM4B is a Master Regulator of the Estrogen Receptor Signalling Cascade

por Gaughan, Luke, Stockley, Jacqueline, Coffey, Kelly, O’Neill, Daniel, Jones, Dominic L., Wade, Mark, Wright, Jamie, Moore, Madeleine, Tse, Sandy, Rogerson, Lynsey, Robson, Craig N.
Publicado 2013

Adolescent cognitive control and mediofrontal theta oscillations are disrupted by neglect: Associations with transdiagnostic risk for psychopathology in a randomized controlled tri...

por Buzzell, George A., Troller-Renfree, Sonya V., Wade, Mark, Debnath, Ranjan, Morales, Santiago, Bowers, Maureen E., Zeanah, Charles H., Nelson, Charles A., Fox, Nathan A.
Publicado 2020

Examining the Human Element in Lab Biosafety

por Haile, Betiel H., Wade, Mark, Blevins, Patricia, Cannons, Andrew, France, Richard, Ferland, D., Shaikh, Affan, Park, Meeyoung, Erondu, Ngozi, Kaufman, Sean G., McNabb, Scott J.
Publicado 2014

Development and exploitation of a novel mutant androgen receptor modelling strategy to identify new targets for advanced prostate cancer therapy

por O'Neill, Daniel, Jones, Dominic, Wade, Mark, Grey, James, Nakjang, Sirintra, Guo, Wenrui, Cork, David, Davies, Barry R., Wedge, Steve R., Robson, Craig N., Gaughan, Luke
Publicado 2015

Circ-ZNF609 Is a Circular RNA that Can Be Translated and Functions in Myogenesis

por Legnini, Ivano, Di Timoteo, Gaia, Rossi, Francesca, Morlando, Mariangela, Briganti, Francesca, Sthandier, Olga, Fatica, Alessandro, Santini, Tiziana, Andronache, Adrian, Wade, Mark, Laneve, Pietro, Rajewsky, Nikolaus, Bozzoni, Irene
Publicado 2017

Early deprivation alters structural brain development from middle childhood to adolescence

por Sheridan, Margaret A., Mukerji, Cora E., Wade, Mark, Humphreys, Kathryn L., Garrisi, Kathryn, Goel, Srishti, Patel, Kinjal, Fox, Nathan A., Zeanah, Charles H., Nelson, Charles A., McLaughlin, Katie A.
Publicado 2022

Cognitive and Emotional Well-Being of Preschool Children Before and During the COVID-19 Pandemic

por Finegold, Katherine E., Knight, Julia A., Hung, Rayjean J., Ssewanyana, Derrick, Wong, Jody, Bertoni, Kashtin, Adel Khani, Nadya, Watson, Harmoni, Levitan, Robert D., Jenkins, Jennifer M., Matthews, Stephen G., Wade, Mark
Publicado 2023

The anti-obesity effect of FGF19 does not require UCP1-dependent thermogenesis

por Antonellis, Patrick J., Droz, Brian A., Cosgrove, Richard, O'Farrell, Libbey S., Coskun, Tamer, Perfield, James W., Bauer, Steven, Wade, Mark, Chouinard, Tara E., Brozinick, Joseph T., Adams, Andrew C., Samms, Ricardo J.
Publicado 2019

P1031: PRELIMINARY DATA FROM THE PHASE 1/2 STUDY OF TP-3654, AN INVESTIGATIONAL SELECTIVE PIM1 KINASE INHIBITOR, SHOWED CYTOKINE REDUCTION AND CLINICAL RESPONSES IN RELAPSED/REFRAC...

por El Chaer, Firas, Rein, Lindsay, Shimoda, Kazuya, Yuda, Junichiro, Haque, Tamanna, Mccloskey, James, Takami, Akiyoshi, Fukaya, Masafumi, Shirane, Shuichi, Kabir, Sujan, Mei, Jian, LI, Zhonggai, Wade, Mark, Lebedinsky, Claudia, Rampal, Raajit K
Publicado 2023

Window-of-Opportunity Study of Valproic Acid in Breast Cancer Testing a Gene Expression Biomarker

por Cohen, Adam L., Neumayer, Leigh, Boucher, Ken, Factor, Rachel E., Shrestha, Gajendra, Wade, Mark, Lamb, John G., Arbogast, Kylee, Piccolo, Stephen R., Riegert, Joanna, Schabel, Matthias, Bild, Andrea H., Werner, Theresa L.
Publicado 2017

Common cancer-associated imbalances in the DNA damage response confer sensitivity to single agent ATR inhibition

por Middleton, Fiona K., Patterson, Miranda J., Elstob, Claire J., Fordham, Sarah, Herriott, Ashleigh, Wade, Mark A., McCormick, Aiste, Edmondson, Richard, May, Felicity E.B., Allan, James M., Pollard, John R., Curtin, Nicola J.
Publicado 2015

Phosphoproteomics reveals rewiring of the insulin signaling network and multi-nodal defects in insulin resistance

por Fazakerley, Daniel J., van Gerwen, Julian, Cooke, Kristen C., Duan, Xiaowen, Needham, Elise J., Díaz-Vegas, Alexis, Madsen, Søren, Norris, Dougall M., Shun-Shion, Amber S., Krycer, James R., Burchfield, James G., Yang, Pengyi, Wade, Mark R., Brozinick, Joseph T., James, David E., Humphrey, Sean J.
Publicado 2023

JNJ-64041757 (JNJ-757), a Live, Attenuated, Double-Deleted Listeria monocytogenes–Based Immunotherapy in Patients With NSCLC: Results From Two Phase 1 Studies

por Brahmer, Julie R., Johnson, Melissa L., Cobo, Manuel, Viteri, Santiago, Sarto, Juan Coves, Sukari, Ammar, Awad, Mark M., Salgia, Ravi, Papadimitrakopoulou, Vali A., Rajan, Arun, Bandyopadhyay, Nibedita, Allred, Alicia J., Wade, Mark, Mason, Gary E., Zudaire, Enrique, Knoblauch, Roland E., Stone, Nicole, Lorenzi, Matthew V., Hassan, Raffit
Publicado 2020

The Pleiotropic Actions of Adiponectin are Initiated via Receptor-Mediated Activation of Ceramidase Activity

por Holland, William L., Miller, Russell A., Wang, Zhao V., Sun, Kai, Barth, Brian M., Bui, Hai H., Davis, Kathryn E., Bikman, Benjamin T., Halberg, Nils, Rutkowski, Joseph M., Wade, Mark R., Tenorio, Vincent M., Kuo, Ming-Shang, Brozinick, Joseph T., Zhang, Bei B., Birnbaum, Morris J., Summers, Scott A., Scherer, Philipp E.
Publicado 2010

Safety and preliminary immunogenicity of JNJ-64041809, a live-attenuated, double-deleted Listeria monocytogenes-based immunotherapy, in metastatic castration-resistant prostate can...

por Drake, Charles G., Pachynski, Russell K., Subudhi, Sumit K., McNeel, Douglas G., Antonarakis, Emmanuel S., Bauer, Todd M., Lauer, Peter, Brockstedt, Dirk, Patricia, Daniel, Wade, Mark, Zudaire, Enrique, Bandyopadhyay, Nibedita, Parasrampuria, Dolly A., Girgis, Suzette, Mason, Gary E., Knoblauch, Roland E., Stone, Nicole, Infante, Jeffrey R., Gottardis, Marco M., Fong, Lawrence
Publicado 2021

Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead

por Goodson, William H., Lowe, Leroy, Carpenter, David O., Gilbertson, Michael, Manaf Ali, Abdul, Lopez de Cerain Salsamendi, Adela, Lasfar, Ahmed, Carnero, Amancio, Azqueta, Amaya, Amedei, Amedeo, Charles, Amelia K., Collins, Andrew R., Ward, Andrew, Salzberg, Anna C., Colacci, Anna Maria, Olsen, Ann-Karin, Berg, Arthur, Barclay, Barry J., Zhou, Binhua P., Blanco-Aparicio, Carmen, Baglole, Carolyn J., Dong, Chenfang, Mondello, Chiara, Hsu, Chia-Wen, Naus, Christian C., Yedjou, Clement, Curran, Colleen S., Laird, Dale W., Koch, Daniel C., Carlin, Danielle J., Felsher, Dean W., Roy, Debasish, Brown, Dustin G., Ratovitski, Edward, Ryan, Elizabeth P., Corsini, Emanuela, Rojas, Emilio, Moon, Eun-Yi, Laconi, Ezio, Marongiu, Fabio, Al-Mulla, Fahd, Chiaradonna, Ferdinando, Darroudi, Firouz, Martin, Francis L., Van Schooten, Frederik J., Goldberg, Gary S., Wagemaker, Gerard, Nangami, Gladys N., Calaf, Gloria M., Williams, Graeme P., Wolf, Gregory T., Koppen, Gudrun, Brunborg, Gunnar, Lyerly, H. Kim, Krishnan, Harini, Ab Hamid, Hasiah, Yasaei, Hemad, Sone, Hideko, Kondoh, Hiroshi, Salem, Hosni K., Hsu, Hsue-Yin, Park, Hyun Ho, Koturbash, Igor, Miousse, Isabelle R., Scovassi, A.Ivana, Klaunig, James E., Vondráček, Jan, Raju, Jayadev, Roman, Jesse, Wise, John Pierce, Whitfield, Jonathan R., Woodrick, Jordan, Christopher, Joseph A., Ochieng, Josiah, Martinez-Leal, Juan Fernando, Weisz, Judith, Kravchenko, Julia, Sun, Jun, Prudhomme, Kalan R., Narayanan, Kannan Badri, Cohen-Solal, Karine A., Moorwood, Kim, Gonzalez, Laetitia, Soucek, Laura, Jian, Le, D’Abronzo, Leandro S., Lin, Liang-Tzung, Li, Lin, Gulliver, Linda, McCawley, Lisa J., Memeo, Lorenzo, Vermeulen, Louis, Leyns, Luc, Zhang, Luoping, Valverde, Mahara, Khatami, Mahin, Romano, Maria Fiammetta, Chapellier, Marion, Williams, Marc A., Wade, Mark, Manjili, Masoud H., Lleonart, Matilde E., Xia, Menghang, Gonzalez Guzman, Michael J., Karamouzis, Michalis V., Kirsch-Volders, Micheline, Vaccari, Monica, Kuemmerle, Nancy B., Singh, Neetu, Cruickshanks, Nichola, Kleinstreuer, Nicole, van Larebeke, Nik, Ahmed, Nuzhat, Ogunkua, Olugbemiga, Krishnakumar, P.K., Vadgama, Pankaj, Marignani, Paola A., Ghosh, Paramita M., Ostrosky-Wegman, Patricia, Thompson, Patricia A., Dent, Paul, Heneberg, Petr, Darbre, Philippa, Leung, Po Sing, Nangia-Makker, Pratima, Cheng, Qiang (Shawn), Robey, R.Brooks, Al-Temaimi, Rabeah, Roy, Rabindra, Andrade-Vieira, Rafaela, Sinha, Ranjeet K., Mehta, Rekha, Vento, Renza, Di Fiore, Riccardo, Ponce-Cusi, Richard, Dornetshuber-Fleiss, Rita, Nahta, Rita, Castellino, Robert C., Palorini, Roberta, Hamid, Roslida A., Langie, Sabine A.S., Eltom, Sakina E., Brooks, Samira A., Ryeom, Sandra, Wise, Sandra S., Bay, Sarah N., Harris, Shelley A., Papagerakis, Silvana, Romano, Simona, Pavanello, Sofia, Eriksson, Staffan, Forte, Stefano, Casey, Stephanie C., Luanpitpong, Sudjit, Lee, Tae-Jin, Otsuki, Takemi, Chen, Tao, Massfelder, Thierry, Sanderson, Thomas, Guarnieri, Tiziana, Hultman, Tove, Dormoy, Valérian, Odero-Marah, Valerie, Sabbisetti, Venkata, Maguer-Satta, Veronique, Rathmell, W.Kimryn, Engström, Wilhelm, Decker, William K., Bisson, William H., Rojanasakul, Yon, Luqmani, Yunus, Chen, Zhenbang, Hu, Zhiwei
Publicado 2015