APLP2 Regulates Refractive Error and Myopia Development in Mice and Humans

por Tkatchenko, Andrei V., Tkatchenko, Tatiana V., Guggenheim, Jeremy A., Verhoeven, Virginie J. M., Hysi, Pirro G., Wojciechowski, Robert, Singh, Pawan Kumar, Kumar, Ashok, Thinakaran, Gopal, Williams, Cathy
Publicado 2015

Time Spent Outdoors Partly Accounts for the Effect of Education on Myopia

por Clark, Rosie, Kneepkens, Sander C. M., Plotnikov, Denis, Shah, Rupal L., Huang, Yu, Tideman, J. Willem L., Klaver, Caroline C. W., Atan, Denize, Williams, Cathy, Guggenheim, Jeremy A.
Publicado 2023

The MUK five protocol: a phase II randomised, controlled, parallel group, multi-centre trial of carfilzomib, cyclophosphamide and dexamethasone (CCD) vs. cyclophosphamide, bortezom...

por Brown, Sarah, Hinsley, Samantha, Ballesteros, Mónica, Bourne, Sue, McGarry, Paul, Sherratt, Debbie, Flanagan, Louise, Gregory, Walter, Cavenagh, Jamie, Owen, Roger, Williams, Cathy, Kaiser, Martin, Low, Eric, Yong, Kwee
Publicado 2016

A genome-wide association study for corneal curvature identifies the platelet-derived growth factor receptor alpha gene as a quantitative trait locus for eye size in white European...

por Guggenheim, Jeremy A., McMahon, George, Kemp, John P., Akhtar, Saeed, St Pourcain, Beate, Northstone, Kate, Ring, Susan M., Evans, David M., Smith, George Davey, Timpson, Nicholas J., Williams, Cathy
Publicado 2013

The role of ixazomib as an augmented conditioning therapy in salvage autologous stem cell transplant (ASCT) and as a post-ASCT consolidation and maintenance strategy in patients wi...

por Striha, Alina, Ashcroft, A. John, Hockaday, Anna, Cairns, David A., Boardman, Karen, Jacques, Gwen, Williams, Cathy, Snowden, John A., Garg, Mamta, Cavenagh, Jamie, Yong, Kwee, Drayson, Mark T., Owen, Roger, Cook, Mark, Cook, Gordon
Publicado 2018

Association of genetic variants with patient reported quality of life and pain experience in patients in the UK NCRI Myeloma X Relapse [Intensive]) trial; an exploratory study

por Snowden, John A., Ahmedzai, Sam H., Cox, Angela, Cairns, David A., Ashcroft, A. John, Williams, Cathy, Cavenagh, Jamie D., Hockaday, Anna, Brown, Julia M., Brock, Ian W., Morris, Treen C. M., Cook, Gordon
Publicado 2022

Evidence That Emmetropization Buffers Against Both Genetic and Environmental Risk Factors for Myopia

por Pozarickij, Alfred, Enthoven, Clair A., Ghorbani Mojarrad, Neema, Plotnikov, Denis, Tedja, Milly S., Haarman, Annechien E G., Tideman, J. Willem L., Polling, Jan Roelof, Northstone, Kate, Williams, Cathy, Klaver, Caroline C. W., Guggenheim, Jeremy A.
Publicado 2020

Genetic Variants Associated With Human Eye Size Are Distinct From Those Conferring Susceptibility to Myopia

por Plotnikov, Denis, Cui, Jiangtian, Clark, Rosie, Wedenoja, Juho, Pärssinen, Olavi, Tideman, J. Willem L., Jonas, Jost B., Wang, Yaxing, Rudan, Igor, Young, Terri L., Mackey, David A., Terry, Louise, Williams, Cathy, Guggenheim, Jeremy A.
Publicado 2021

Whole exome sequence analysis in 51 624 participants identifies novel genes and variants associated with refractive error and myopia

por Guggenheim, Jeremy A, Clark, Rosie, Cui, Jiangtian, Terry, Louise, Patasova, Karina, Haarman, Annechien E G, Musolf, Anthony M, Verhoeven, Virginie J M, Klaver, Caroline C W, Bailey-Wilson, Joan E, Hysi, Pirro G, Williams, Cathy
Publicado 2022

Drainage, irrigation and fibrinolytic therapy (DRIFT) for posthaemorrhagic ventricular dilatation: 10-year follow-up of a randomised controlled trial

por Luyt, Karen, Jary, Sally L, Lea, Charlotte L, Young, Grace J., Odd, David E, Miller, Helen E, Kmita, Grazyna, Williams, Cathy, Blair, Peter S, Hollingworth, William, Morgan, Michelle, Smith-Collins, Adam P, Walker-Cox, Steven, Aquilina, Kristian, Pople, Ian, Whitelaw, Andrew G
Publicado 2020

Time spent outdoors in childhood is associated with reduced risk of myopia as an adult

por Lingham, Gareth, Yazar, Seyhan, Lucas, Robyn M., Milne, Elizabeth, Hewitt, Alex W., Hammond, Christopher J., MacGregor, Stuart, Rose, Kathryn A., Chen, Fred K., He, Mingguang, Guggenheim, Jeremy A., Clarke, Michael W., Saw, Seang-Mei, Williams, Cathy, Coroneo, Minas T., Straker, Leon, Mackey, David A.
Publicado 2021

A new polygenic score for refractive error improves detection of children at risk of high myopia but not the prediction of those at risk of myopic macular degeneration

por Clark, Rosie, Lee, Samantha Sze-Yee, Du, Ran, Wang, Yining, Kneepkens, Sander C.M., Charng, Jason, Huang, Yu, Hunter, Michael L., Jiang, Chen, Tideman, J.Willem L., Melles, Ronald B., Klaver, Caroline C.W., Mackey, David A., Williams, Cathy, Choquet, Hélène, Ohno-Matsui, Kyoko, Guggenheim, Jeremy A.
Publicado 2023

Patient-Reported Outcome Results From the Open-Label, Randomized Phase III Myeloma X Trial Evaluating Salvage Autologous Stem-Cell Transplantation in Relapsed Multiple Myeloma

por Ahmedzai, Sam H., Snowden, John A., Ashcroft, Andrew John, Cairns, David Allan, Williams, Cathy, Hockaday, Anna, Cavenagh, Jamie D., Ademokun, Debo, Tholouli, Eleni, Allotey, David, Dhanapal, Vijay, Jenner, Matthew, Yong, Kwee, Cavet, Jim, Hunter, Hannah, Bird, Jennifer M., Pratt, Guy, Parrish, Christopher, Brown, Julia M., Morris, Treen C.M., Cook, Gordon
Publicado 2019

Lenalidomide maintenance versus observation for patients with newly diagnosed multiple myeloma (Myeloma XI): a multicentre, open-label, randomised, phase 3 trial

por Jackson, Graham H, Davies, Faith E, Pawlyn, Charlotte, Cairns, David A, Striha, Alina, Collett, Corinne, Hockaday, Anna, Jones, John R, Kishore, Bhuvan, Garg, Mamta, Williams, Cathy D, Karunanithi, Kamaraj, Lindsay, Jindriska, Jenner, Matthew W, Cook, Gordon, Russell, Nigel H, Kaiser, Martin F, Drayson, Mark T, Owen, Roger G, Gregory, Walter M, Morgan, Gareth J
Publicado 2019

The impact of cytogenetics on duration of response and overall survival in patients with relapsed multiple myeloma (long‐term follow‐up results from BSBMT/UKMF Myeloma X Relapse [I...

por Cook, Gordon, Royle, Kara‐Louise, O'Connor, Sheila, Cairns, David A., Ashcroft, A. John, Williams, Cathy D., Hockaday, Anna, Cavenagh, Jamie D., Snowden, John A., Ademokun, Debo, Tholouli, Eleni, Andrews, Vivienne E., Jenner, Matthew, Parrish, Christopher, Yong, Kwee, Cavet, Jim, Hunter, Hannah, Bird, Jenny M., Pratt, Guy, Drayson, Mark T., Brown, Julia M., Morris, Treen C. M.
Publicado 2019

Response-adapted intensification with cyclophosphamide, bortezomib, and dexamethasone versus no intensification in patients with newly diagnosed multiple myeloma (Myeloma XI): a mu...

por Jackson, Graham H, Davies, Faith E, Pawlyn, Charlotte, Cairns, David A, Striha, Alina, Collett, Corinne, Waterhouse, Anna, Jones, John R, Kishore, Bhuvan, Garg, Mamta, Williams, Cathy D, Karunanithi, Kamaraj, Lindsay, Jindriska, Wilson, Jamie N, Jenner, Matthew W, Cook, Gordon, Kaiser, Martin F, Drayson, Mark T, Owen, Roger G, Russell, Nigel H, Gregory, Walter M, Morgan, Gareth J
Publicado 2019

Lenalidomide before and after autologous stem cell transplantation for transplant-eligible patients of all ages in the randomized, phase III, Myeloma XI trial

por Jackson, Graham H., Davies, Faith E., Pawlyn, Charlotte, Cairns, David A., Striha, Alina, Collett, Corinne, Waterhouse, Anna, Jones, John R., Kishore, Bhuvan, Garg, Mamta, Williams, Cathy D., Karunanithi, Kamaraj, Lindsay, Jindriska, Allotey, David, Shafeek, Salim, Jenner, Matthew W., Cook, Gordon, Russell, Nigel H., Kaiser, Martin F., Drayson, Mark T., Owen, Roger G., Gregory, Walter M., Morgan, Gareth J.
Publicado 2021

Carfilzomib, lenalidomide, dexamethasone, and cyclophosphamide (KRdc) as induction therapy for transplant-eligible, newly diagnosed multiple myeloma patients (Myeloma XI+): Interim...

por Jackson, Graham H., Pawlyn, Charlotte, Cairns, David A., de Tute, Ruth M., Hockaday, Anna, Collett, Corinne, Jones, John R., Kishore, Bhuvan, Garg, Mamta, Williams, Cathy D., Karunanithi, Kamaraj, Lindsay, Jindriska, Rocci, Alberto, Snowden, John A., Jenner, Matthew W., Cook, Gordon, Russell, Nigel H., Drayson, Mark T., Gregory, Walter M., Kaiser, Martin F., Owen, Roger G., Davies, Faith E., Morgan, Gareth J.
Publicado 2021

Childhood gene-environment interactions and age-dependent effects of genetic variants associated with refractive error and myopia: The CREAM Consortium

por Fan, Qiao, Guo, Xiaobo, Tideman, J. Willem L., Williams, Katie M., Yazar, Seyhan, Hosseini, S. Mohsen, Howe, Laura D., Pourcain, Beaté St, Evans, David M., Timpson, Nicholas J., McMahon, George, Hysi, Pirro G., Krapohl, Eva, Wang, Ya Xing, Jonas, Jost B., Baird, Paul Nigel, Wang, Jie Jin, Cheng, Ching-Yu, Teo, Yik-Ying, Wong, Tien-Yin, Ding, Xiaohu, Wojciechowski, Robert, Young, Terri L., Pärssinen, Olavi, Oexle, Konrad, Pfeiffer, Norbert, Bailey-Wilson, Joan E., Paterson, Andrew D., Klaver, Caroline C. W., Plomin, Robert, Hammond, Christopher J., Mackey, David A., He, Mingguang, Saw, Seang-Mei, Williams, Cathy, Guggenheim, Jeremy A.
Publicado 2016

A genome-wide association study of corneal astigmatism: The CREAM Consortium

por Shah, Rupal L., Li, Qing, Zhao, Wanting, Tedja, Milly S., Tideman, J. Willem L., Khawaja, Anthony P., Fan, Qiao, Yazar, Seyhan, Williams, Katie M., Verhoeven, Virginie J.M., Xie, Jing, Wang, Ya Xing, Hess, Moritz, Nickels, Stefan, Lackner, Karl J., Pärssinen, Olavi, Wedenoja, Juho, Biino, Ginevra, Concas, Maria Pina, Uitterlinden, André, Rivadeneira, Fernando, Jaddoe, Vincent W.V., Hysi, Pirro G., Sim, Xueling, Tan, Nicholas, Tham, Yih-Chung, Sensaki, Sonoko, Hofman, Albert, Vingerling, Johannes R., Jonas, Jost B., Mitchell, Paul, Hammond, Christopher J., Höhn, René, Baird, Paul N., Wong, Tien-Yin, Cheng, Chinfsg-Yu, Teo, Yik Ying, Mackey, David A., Williams, Cathy, Saw, Seang-Mei, Klaver, Caroline C.W., Guggenheim, Jeremy A., Bailey-Wilson, Joan E.
Publicado 2018