Domain-specific insight into the recognition of BH3-death motifs by the pro-survival Bcl-2 protein

por Mushtaq, Ameeq Ul, Ådén, Jörgen, Ali, Katan, Gröbner, Gerhard
Publicado 2022

Insight into Functional Membrane Proteins by Solution NMR: The Human Bcl-2 Protein—A Promising Cancer Drug Target

por Ul Mushtaq, Ameeq, Ådén, Jörgen, Sparrman, Tobias, Hedenström, Mattias, Gröbner, Gerhard
Publicado 2021

Backbone chemical shift assignment and dynamics of the N-terminal domain of ClpB from Francisella tularensis type VI secretion system

por Mushtaq, Ameeq Ul, Ådén, Jörgen, Alam, Athar, Sjöstedt, Anders, Gröbner, Gerhard
Publicado 2022

Dissociation between the critical role of ClpB of Francisella tularensis for the heat shock response and the DnaK interaction and its important role for efficient type VI secretion...

por Alam, Athar, Golovliov, Igor, Javed, Eram, Kumar, Rajender, Ådén, Jörgen, Sjöstedt, Anders
Publicado 2020

A Capped Peptide of the Aggregation Prone NAC 71–82 Amino Acid Stretch of α-Synuclein Folds into Soluble β-Sheet Oligomers at Low and Elevated Peptide Concentrations

por Näsström, Thomas, Ådén, Jörgen, Shibata, Fumina, Andersson, Per Ola, Karlsson, Björn C.G.
Publicado 2020

Creation of distinctive Bax-lipid complexes at mitochondrial membrane surfaces drives pore formation to initiate apoptosis

por Clifton, Luke A., Wacklin-Knecht, Hanna P., Ådén, Jörgen, Mushtaq, Ameeq Ul, Sparrman, Tobias, Gröbner, Gerhard
Publicado 2023

Structural basis for catalytically restrictive dynamics of a high-energy enzyme state

por Kovermann, Michael, Ådén, Jörgen, Grundström, Christin, Elisabeth Sauer-Eriksson, A., Sauer, Uwe H., Wolf-Watz, Magnus
Publicado 2015

Synthetic NAC 71-82 Peptides Designed to Produce Fibrils with Different Protofilament Interface Contacts

por Näsström, Thomas, Dahlberg, Tobias, Malyshev, Dmitry, Ådén, Jörgen, Andersson, Per Ola, Andersson, Magnus, Karlsson, Björn C. G.
Publicado 2021

Correlated Inter-Domain Motions in Adenylate Kinase

por Esteban-Martín, Santiago, Fenwick, Robert Bryn, Ådén, Jörgen, Cossins, Benjamin, Bertoncini, Carlos W., Guallar, Victor, Wolf-Watz, Magnus, Salvatella, Xavier
Publicado 2014

Bacterial Chaperones CsgE and CsgC Differentially Modulate Human α-Synuclein Amyloid Formation via Transient Contacts

por Chorell, Erik, Andersson, Emma, Evans, Margery L., Jain, Neha, Götheson, Anna, Åden, Jörgen, Chapman, Matthew R., Almqvist, Fredrik, Wittung-Stafshede, Pernilla
Publicado 2015

The Small Molecule Alpha-Synuclein Aggregator, FN075, Enhances Alpha-Synuclein Pathology in Subclinical AAV Rat Models

por Kelly, Rachel, Cairns, Andrew G., Ådén, Jörgen, Almqvist, Fredrik, Bemelmans, Alexis-Pierre, Brouillet, Emmanuel, Patton, Tommy, McKernan, Declan P., Dowd, Eilís
Publicado 2021

Neutron reflectometry and NMR spectroscopy of full-length Bcl-2 protein reveal its membrane localization and conformation

por Mushtaq, Ameeq Ul, Ådén, Jörgen, Clifton, Luke A., Wacklin-Knecht, Hanna, Campana, Mario, Dingeldein, Artur P. G., Persson, Cecilia, Sparrman, Tobias, Gröbner, Gerhard
Publicado 2021

Intramolecular Povarov Reactions for the Synthesis of Chromenopyridine Fused 2-Pyridone Polyheterocycles Binding to α-Synuclein and Amyloid-β Fibrils

por Adolfsson, Dan E., Tyagi, Mohit, Singh, Pardeep, Deuschmann, Adrian, Ådén, Jörgen, Gharibyan, Anna L., Jayaweera, Sanduni Wasana, Lindgren, Anders E. G., Olofsson, Anders, Almqvist, Fredrik
Publicado 2020

Tandem Ring Opening/Intramolecular [2 + 2] Cycloaddition Reaction for the Synthesis of Cyclobutane Fused Thiazolino-2-Pyridones

por Tyagi, Mohit, Adolfsson, Dan E., Singh, Pardeep, Ådén, Jörgen, Jayaweera, Sanduni Wasana, Gharibyan, Anna, Bharate, Jaideep B., Kiss, Anita, Sarkar, Souvik, Olofsson, Anders, Almqvist, Fredrik
Publicado 2021

Protein-lipid interaction at low pH induces oligomerization of the MakA cytotoxin from Vibrio cholerae

por Nadeem, Aftab, Berg, Alexandra, Pace, Hudson, Alam, Athar, Toh, Eric, Ådén, Jörgen, Zlatkov, Nikola, Myint, Si Lhyam, Persson, Karina, Gröbner, Gerhard, Sjöstedt, Anders, Bally, Marta, Barandun, Jonas, Uhlin, Bernt Eric, Wai, Sun Nyunt
Publicado 2022