Investigating molecular interactions between oxidized neuroglobin and cytochrome c

por Tiwari, Purushottam B., Chapagain, Prem P., Üren, Aykut
Publicado 2018

Helix-A peptide prevents gp120-mediated neuronal loss

por Avdoshina, Valeria, Taraballi, Francesca, Tasciotti, Ennio, Üren, Aykut, Mocchetti, Italo
Publicado 2019

Identification of undecylenic acid as EAG channel inhibitor using surface plasmon resonance-based screen of KCNH channels

por Wang, Ze-Jun, Tiwari, Purushottam B., Üren, Aykut, Brelidze, Tinatin I.
Publicado 2019

Investigating cyclic nucleotide and cyclic dinucleotide binding to HCN channels by surface plasmon resonance

por Hayoz, Sebastien, Tiwari, Purushottam B., Piszczek, Grzegorz, Üren, Aykut, Brelidze, Tinatin I.
Publicado 2017

Heparin Inhibits Hepatocyte Growth Factor Induced Motility and Invasion of Hepatocellular Carcinoma Cells through Early Growth Response Protein 1

por Ozen, Evin, Gozukizil, Aysim, Erdal, Esra, Uren, Aykut, Bottaro, Donald P., Atabey, Nese
Publicado 2012

YK-4-279 Inhibits ERG and ETV1 Mediated Prostate Cancer Cell Invasion

por Rahim, Said, Beauchamp, Elspeth M., Kong, Yali, Brown, Milton L., Toretsky, Jeffrey A., Üren, Aykut
Publicado 2011

SPRD: a surface plasmon resonance database of common factors for better experimental planning

por Tiwari, Purushottam B., Bencheqroun, Camelia, Lemus, Mario, Shaw, Taryn, Kouassi-Brou, Marilyn, Alaoui, Adil, Üren, Aykut
Publicado 2021

Insulin-Like Growth Factor 1 Receptor as a Therapeutic Target in Ewing Sarcoma: Lack of Consistent Upregulation or Recurrent Mutation and a Review of the Clinical Trial Literature

por O'Neill, Alison, Shah, Nilay, Zitomersky, Naamah, Ladanyi, Marc, Shukla, Neerav, Üren, Aykut, Loeb, David, Toretsky, Jeffrey
Publicado 2013

Acetylation Increases EWS-FLI1 DNA Binding and Transcriptional Activity

por Schlottmann, Silke, Erkizan, Hayriye V., Barber-Rotenberg, Julie S., Knights, Chad, Cheema, Amrita, Üren, Aykut, Avantaggiati, Maria L., Toretsky, Jeffrey A.
Publicado 2012

Comprehensive profiling of mRNA splicing indicates that GC content signals altered cassette exon inclusion in Ewing sarcoma

por Graham, Garrett T, Selvanathan, Saravana P, Zöllner, Stefan K, Stahl, Emily, Shlien, Adam, Caplen, Natasha J, Üren, Aykut, Toretsky, Jeffrey A
Publicado 2022

Clofarabine induces ERK/MSK/CREB activation through inhibiting CD99 on Ewing sarcoma cells

por Sevim, Handan, Çelik, Haydar, Düşünceli, Levent, Ceyhan, Ceyda S., Molotkova, Anna, Nakazawa, Kay, Graham, Garrett T., Petro, Jeffrey R., Toretsky, Jeffrey A., Üren, Aykut
Publicado 2021

Characterization of magnesium requirement of human 5'-tyrosyl DNA phosphodiesterase mediated reaction

por Adhikari, Sanjay, Karmahapatra, Soumendra K, Karve, Tejaswita M, Bandyopadhyay, Sanjona, Woodrick, Jordan, Manthena, Praveen V, Glasgow, Eric, Byers, Stephen, Saha, Tapas, Uren, Aykut
Publicado 2012

Small Molecule Binds with Lymphocyte Antigen 6K to Induce Cancer Cell Death

por Benti, Senyi, Tiwari, Purushottam B., Goodlett, Dustin W., Daneshian, Leily, Kern, Grant B., Smith, Mark D., Uren, Aykut, Chruszcz, Maksymilian, Shimizu, Linda S., Upadhyay, Geeta
Publicado 2020

Pharmacokinetic modeling optimizes inhibition of the ‘undruggable’ EWS-FLI1 transcription factor in Ewing Sarcoma

por Hong, Sung-Hyeok, Youbi, Sarah. E., Hong, S. Peter, Kallakury, Bhaskar, Monroe, Phillip, Erkizan, Hayriye V, Barber-Rotenberg, Julie S., Houghton, Peter, Üren, Aykut, Toretsky, Jeffrey A.
Publicado 2013

Synthesis and Structure–Activity Relationship Studies of Small Molecule Disruptors of EWS-FLI1 Interactions in Ewing’s Sarcoma

por Tosso, Perrer N., Kong, Yali, Scher, Lauren, Cummins, Ryan, Schneider, Jeffrey, Rahim, Said, Holman, K. Travis, Toretsky, Jeffrey, Wang, Kan, Üren, Aykut, Brown, Milton L.
Publicado 2014

Ezrin Enhances EGFR Signaling and Modulates Erlotinib Sensitivity in Non–Small Cell Lung Cancer Cells()

por Saygideğer-Kont, Yasemin, Minas, Tsion Zewdu, Jones, Hayden, Hour, Sarah, Çelik, Haydar, Temel, Idil, Han, Jenny, Atabey, Nese, Erkizan, Hayriye Verda, Toretsky, Jeffrey A., Üren, Aykut
Publicado 2016

Beta-Catenin Accelerates Human Papilloma Virus Type-16 Mediated Cervical Carcinogenesis in Transgenic Mice

por Bulut, Gülay, Fallen, Shannon, Beauchamp, Elspeth M., Drebing, Lauren E., Sun, Junfeng, Berry, Deborah L., Kallakury, Bhaskar, Crum, Christopher P., Toretsky, Jeffrey A., Schlegel, Richard, Üren, Aykut
Publicado 2011

Targeting the Non-catalytic RVxF Site of Protein Phosphatase-1 With Small Molecules for Ebola Virus Inhibition

por Lin, Xionghao, Ammosova, Tatiana, Choy, Meng S., Pietzsch, Colette A., Ivanov, Andrey, Ahmad, Asrar, Saygideğer, Yasemin, Kumari, Namita, Kovalskyy, Dmytro, Üren, Aykut, Peti, Wolfgang, Bukreyev, Alexander, Nekhai, Sergei
Publicado 2019

Small molecule selected to disrupt oncogenic protein EWS-FLI1 interaction with RNA Helicase A inhibits Ewing's Sarcoma

por Erkizan, Hayriye V., Kong, Yali, Merchant, Melinda, Schlottmann, Silke, Barber-Rotenberg, Julie S., Abaan, Ogan D., Chou, Tsu-hang, Dakshanamurthy, Sivanesan, Brown, Milton L., Üren, Aykut, Toretsky, Jeffrey A.
Publicado 2009

Antimitotic activity of DY131 and the estrogen-related receptor beta 2 (ERRβ2) splice variant in breast cancer

por Heckler, Mary M., Zeleke, Tizita Zewde, Divekar, Shailaja D., Fernandez, Aileen I., Tiek, Deanna M., Woodrick, Jordan, Farzanegan, Alexander, Roy, Rabindra, Üren, Aykut, Mueller, Susette C., Riggins, Rebecca B.
Publicado 2016