Mid-Gestation lethality of Atxn2l-Ablated Mice

por Key, Jana, Harter, Patrick N., Sen, Nesli-Ece, Gradhand, Elise, Auburger, Georg, Gispert, Suzana
Publicado 2020

Both Ubiquitin Ligases FBXW8 and PARK2 Are Sequestrated into Insolubility by ATXN2 PolyQ Expansions, but Only FBXW8 Expression Is Dysregulated

por Halbach, Melanie Vanessa, Stehning, Tanja, Damrath, Ewa, Jendrach, Marina, Şen, Nesli Ece, Başak, A. Nazlı, Auburger, Georg
Publicado 2015

SerThr-PhosphoProteome of Brain from Aged PINK1-KO+A53T-SNCA Mice Reveals pT1928-MAP1B and pS3781-ANK2 Deficits, as Hub between Autophagy and Synapse Changes

por Auburger, Georg, Gispert, Suzana, Torres-Odio, Sylvia, Jendrach, Marina, Brehm, Nadine, Canet-Pons, Júlia, Key, Jana, Sen, Nesli-Ece
Publicado 2019

TR-FRET-Based Immunoassay to Measure Ataxin-2 as a Target Engagement Marker in Spinocerebellar Ataxia Type 2

por Bux, Jessica, Sen, Nesli Ece, Klink, Isa-Maria, Hauser, Stefan, Synofzik, Matthis, Schöls, Ludger, Auburger, Georg, Riess, Olaf, Hübener-Schmid, Jeannette
Publicado 2023

Systematic Surveys of Iron Homeostasis Mechanisms Reveal Ferritin Superfamily and Nucleotide Surveillance Regulation to be Modified by PINK1 Absence

por Key, Jana, Sen, Nesli Ece, Arsović, Aleksandar, Krämer, Stella, Hülse, Robert, Khan, Natasha Nadeem, Meierhofer, David, Gispert, Suzana, Koepf, Gabriele, Auburger, Georg
Publicado 2020

In Human and Mouse Spino-Cerebellar Tissue, Ataxin-2 Expansion Affects Ceramide-Sphingomyelin Metabolism

por Sen, Nesli-Ece, Arsovic, Aleksandar, Meierhofer, David, Brodesser, Susanne, Oberschmidt, Carola, Canet-Pons, Júlia, Kaya, Zeynep-Ece, Halbach, Melanie-Vanessa, Gispert, Suzana, Sandhoff, Konrad, Auburger, Georg
Publicado 2019

Mouse Ataxin-2 Expansion Downregulates CamKII and Other Calcium Signaling Factors, Impairing Granule—Purkinje Neuron Synaptic Strength

por Arsović, Aleksandar, Halbach, Melanie Vanessa, Canet-Pons, Júlia, Esen-Sehir, Dilhan, Döring, Claudia, Freudenberg, Florian, Czechowska, Nicoletta, Seidel, Kay, Baader, Stephan L., Gispert, Suzana, Sen, Nesli-Ece, Auburger, Georg
Publicado 2020