Molecular mechanisms of CRISPR-mediated microbial immunity

por Gasiunas, Giedrius, Sinkunas, Tomas, Siksnys, Virginijus
Publicado 2013

Structural basis of DNA target recognition by the B3 domain of Arabidopsis epigenome reader VAL1

por Sasnauskas, Giedrius, Kauneckaitė, Kotryna, Siksnys, Virginijus
Publicado 2018

Degenerate sequence recognition by the monomeric restriction enzyme: single mutation converts BcnI into a strand-specific nicking endonuclease

por Kostiuk, Georgij, Sasnauskas, Giedrius, Tamulaitiene, Giedre, Siksnys, Virginijus
Publicado 2011

Target site cleavage by the monomeric restriction enzyme BcnI requires translocation to a random DNA sequence and a switch in enzyme orientation

por Sasnauskas, Giedrius, Kostiuk, Georgij, Tamulaitis, Gintautas, Siksnys, Virginijus
Publicado 2011

The recognition domain of the methyl-specific endonuclease McrBC flips out 5-methylcytosine

por Sukackaite, Rasa, Grazulis, Saulius, Tamulaitis, Gintautas, Siksnys, Virginijus
Publicado 2012

Template-directed addition of nucleosides to DNA by the BfiI restriction enzyme

por Sasnauskas, Giedrius, Connolly, Bernard A., Halford, Stephen E., Siksnys, Virginijus
Publicado 2008

Structural mechanisms for the 5′-CCWGG sequence recognition by the N- and C-terminal domains of EcoRII

por Golovenko, Dmitrij, Manakova, Elena, Tamulaitiene, Giedre, Grazulis, Saulius, Siksnys, Virginijus
Publicado 2009

Crystal structure of the R-protein of the multisubunit ATP-dependent restriction endonuclease NgoAVII

por Tamulaitiene, Giedre, Silanskas, Arunas, Grazulis, Saulius, Zaremba, Mindaugas, Siksnys, Virginijus
Publicado 2014

Structure-guided sequence specificity engineering of the modification-dependent restriction endonuclease LpnPI

por Sasnauskas, Giedrius, Zagorskaitė, Evelina, Kauneckaitė, Kotryna, Tamulaitiene, Giedre, Siksnys, Virginijus
Publicado 2015

Nucleotide flipping by restriction enzymes analyzed by 2-aminopurine steady-state fluorescence

por Tamulaitis, Gintautas, Zaremba, Mindaugas, Szczepanowski, Roman H., Bochtler, Matthias, Siksnys, Virginijus
Publicado 2007

How PspGI, catalytic domain of EcoRII and Ecl18kI acquire specificities for different DNA targets

por Tamulaitis, Gintautas, Zaremba, Mindaugas, Szczepanowski, Roman H., Bochtler, Matthias, Siksnys, Virginijus
Publicado 2008

CgII cleaves DNA using a mechanism distinct from other ATP-dependent restriction endonucleases

por Toliusis, Paulius, Zaremba, Mindaugas, Silanskas, Arunas, Szczelkun, Mark D., Siksnys, Virginijus
Publicado 2017

Restriction endonuclease BpuJI specific for the 5′-CCCGT sequence is related to the archaeal Holliday junction resolvase family

por Sukackaite, Rasa, Lagunavicius, Arunas, Stankevicius, Kornelijus, Urbanke, Claus, Venclovas, Česlovas, Siksnys, Virginijus
Publicado 2007

Tetrameric restriction enzymes: expansion to the GIY-YIG nuclease family

por Gasiunas, Giedrius, Sasnauskas, Giedrius, Tamulaitis, Gintautas, Urbanke, Claus, Razaniene, Dalia, Siksnys, Virginijus
Publicado 2008

The Streptococcus thermophilus CRISPR/Cas system provides immunity in Escherichia coli

por Sapranauskas, Rimantas, Gasiunas, Giedrius, Fremaux, Christophe, Barrangou, Rodolphe, Horvath, Philippe, Siksnys, Virginijus
Publicado 2011

Structural mechanisms of the degenerate sequence recognition by Bse634I restriction endonuclease

por Manakova, Elena, Gražulis, Saulius, Zaremba, Mindaugas, Tamulaitiene, Giedre, Golovenko, Dmitrij, Siksnys, Virginijus
Publicado 2012

crRNA and tracrRNA guide Cas9-mediated DNA interference in Streptococcus thermophilus

por Karvelis, Tautvydas, Gasiunas, Giedrius, Miksys, Algirdas, Barrangou, Rodolphe, Horvath, Philippe, Siksnys, Virginijus
Publicado 2013

Functional significance of protein assemblies predicted by the crystal structure of the restriction endonuclease BsaWI

por Tamulaitis, Gintautas, Rutkauskas, Marius, Zaremba, Mindaugas, Grazulis, Saulius, Tamulaitiene, Giedre, Siksnys, Virginijus
Publicado 2015

The dynamics of the monomeric restriction endonuclease BcnI during its interaction with DNA

por Kostiuk, Georgij, Dikić, Jasmina, Schwarz, Friedrich W., Sasnauskas, Giedrius, Seidel, Ralf, Siksnys, Virginijus
Publicado 2017

Structure of the DNA-Bound Spacer Capture Complex of a Type II CRISPR-Cas System

por Wilkinson, Martin, Drabavicius, Gediminas, Silanskas, Arunas, Gasiunas, Giedrius, Siksnys, Virginijus, Wigley, Dale B.
Publicado 2019