Sodium Accumulation and Blood Capillary Rarefaction in the Skin Predispose Spontaneously Hypertensive Rats to Salt Sensitive Hypertension

por Šilhavý, Jan, Mlejnek, Petr, Šimáková, Miroslava, Liška, František, Kubovčiak, Jan, Sticová, Eva, Pravenec, Michal
Publicado 2022

Hypolipidemic and insulin sensitizing effects of salsalate beyond suppressing inflammation in a prediabetic rat model

por Hüttl, Martina, Markova, Irena, Miklánková, Denisa, Zapletalova, Iveta, Kujal, Petr, Šilhavý, Jan, Pravenec, Michal, Malinska, Hana
Publicado 2023

Microarray and qPCR Analysis of Mitochondrial Metabolism Activation during Prenatal and Early Postnatal Development in Rats and Humans with Emphasis on CoQ(10) Biosynthesis

por Krizova, Jana, Hulkova, Martina, Capek, Vaclav, Mlejnek, Petr, Silhavy, Jan, Tesarova, Marketa, Zeman, Jiri, Hansikova, Hana
Publicado 2021

Cap analysis of gene expression reveals alternative promoter usage in a rat model of hypertension

por Dahale, Sonal, Ruiz-Orera, Jorge, Silhavy, Jan, Hübner, Norbert, van Heesch, Sebastiaan, Pravenec, Michal, Atanur, Santosh S
Publicado 2022

Cardioprotective Regimen of Adaptation to Chronic Hypoxia Diversely Alters Myocardial Gene Expression in SHR and SHR-mt(BN) Conplastic Rat Strains

por Nedvedova, Iveta, Kolar, David, Neckar, Jan, Kalous, Martin, Pravenec, Michal, Šilhavý, Jan, Korenkova, Vlasta, Kolar, Frantisek, Zurmanova, Jitka M.
Publicado 2019

Beyond Genes: Inclusion of Alternative Splicing and Alternative Polyadenylation to Assess the Genetic Architecture of Predisposition to Voluntary Alcohol Consumption in Brain of th...

por Lusk, Ryan, Hoffman, Paula L., Mahaffey, Spencer, Rosean, Samuel, Smith, Harry, Silhavy, Jan, Pravenec, Michal, Tabakoff, Boris, Saba, Laura M.
Publicado 2022

CD36 regulates substrates utilisation in brown adipose tissue of spontaneously hypertensive rats: In vitro study

por Silhavy, Jan, Mlejnek, Petr, Šimáková, Miroslava, Marková, Irena, Malínská, Hana, Hüttl, Martina, Kazdová, Ludmila, Kazantsev, Dmitry, Mancini, Massimiliano, Novotný, Jiří, Pravenec, Michal
Publicado 2023

Fumaric Acid Esters Can Block Pro-Inflammatory Actions of Human CRP and Ameliorate Metabolic Disturbances in Transgenic Spontaneously Hypertensive Rats

por Šilhavý, Jan, Zídek, Václav, Mlejnek, Petr, Landa, Vladimír, Šimáková, Miroslava, Strnad, Hynek, Oliyarnyk, Olena, Škop, Vojtěch, Kazdová, Ludmila, Kurtz, Theodore, Pravenec, Michal
Publicado 2014

Effects of Metformin on Tissue Oxidative and Dicarbonyl Stress in Transgenic Spontaneously Hypertensive Rats Expressing Human C-Reactive Protein

por Malínská, Hana, Oliyarnyk, Olena, Škop, Vojtěch, Šilhavý, Jan, Landa, Vladimír, Zídek, Václav, Mlejnek, Petr, Šimáková, Miroslava, Strnad, Hynek, Kazdová, Ludmila, Pravenec, Michal
Publicado 2016

Downregulation of the Glo1 Gene Is Associated with Reduced Adiposity and Ectopic Fat Accumulation in Spontaneously Hypertensive Rats

por Šilhavý, Jan, Malínská, Hana, Hüttl, Martina, Marková, Irena, Oliyarnyk, Olena, Mlejnek, Petr, Šimáková, Miroslava, Liška, František, Kazdová, Ludmila, Moravcová, Radka, Novotný, Jiří, Pravenec, Michal
Publicado 2020

Beneficial Effects of Empagliflozin Are Mediated by Reduced Renal Inflammation and Oxidative Stress in Spontaneously Hypertensive Rats Expressing Human C-Reactive Protein

por Malínská, Hana, Hüttl, Martina, Marková, Irena, Miklánková, Denisa, Hojná, Silvie, Papoušek, František, Šilhavý, Jan, Mlejnek, Petr, Zicha, Josef, Hrdlička, Jaroslav, Pravenec, Michal, Vaněčková, Ivana
Publicado 2022

Hypolipidemic Effects of Beetroot Juice in SHR-CRP and HHTg Rat Models of Metabolic Syndrome: Analysis of Hepatic Proteome

por Šilhavý, Jan, Mlejnek, Petr, Šimáková, Miroslava, Malínská, Hana, Marková, Irena, Hüttl, Martina, Miklánková, Denisa, Kazdová, Ludmila, Vrbacký, Marek, Pecinová, Alena, Mráček, Tomáš, Pravenec, Michal
Publicado 2023

Salsalate ameliorates metabolic disturbances by reducing inflammation in spontaneously hypertensive rats expressing human C-reactive protein and by activating brown adipose tissue...

por Trnovská, Jaroslava, Šilhavý, Jan, Kuda, Ondřej, Landa, Vladimír, Zídek, Václav, Mlejnek, Petr, Šimáková, Miroslava, Strnad, Hynek, Škop, Vojtěch, Oliyarnyk, Olena, Kazdová, Ludmila, Haluzík, Martin, Pravenec, Michal
Publicado 2017

Hepatic Transcriptome Profiling Reveals Lack of Acsm3 Expression in Polydactylous Rats with High-Fat Diet-Induced Hypertriglyceridemia and Visceral Fat Accumulation

por Junková, Kristýna, Mirchi, Lukáš F., Chylíková, Blanka, Janků, Michaela, Šilhavý, Jan, Hüttl, Martina, Marková, Irena, Miklánková, Denisa, Včelák, Josef, Malínská, Hana, Pravenec, Michal, Šeda, Ondřej, Liška, František
Publicado 2021

Targeting of the Plzf Gene in the Rat by Transcription Activator-Like Effector Nuclease Results in Caudal Regression Syndrome in Spontaneously Hypertensive Rats

por Liška, František, Peterková, Renata, Peterka, Miroslav, Landa, Vladimír, Zídek, Václav, Mlejnek, Petr, Šilhavý, Jan, Šimáková, Miroslava, Křen, Vladimír, Starker, Colby G., Voytas, Daniel F., Izsvák, Zsuzsanna, Pravenec, Michal
Publicado 2016

Correction: Targeting of the Plzf Gene in the Rat by Transcription Activator-Like Effector Nuclease Results in Caudal Regression Syndrome in Spontaneously Hypertensive Rats

por Liška, František, Peterková, Renata, Peterka, Miroslav, Landa, Vladimír, Zídek, Václav, Mlejnek, Petr, Šilhavý, Jan, Šimáková, Miroslava, Křen, Vladimír, Starker, Colby G., Voytas, Daniel F., Izsvák, Zsuzsanna, Pravenec, Michal
Publicado 2020

Systems Genetics Approaches in Rat Identify Novel Genes and Gene Networks Associated With Cardiac Conduction

por Adriaens, Michiel E., Lodder, Elisabeth M., Moreno‐Moral, Aida, Šilhavý, Jan, Heinig, Matthias, Glinge, Charlotte, Belterman, Charly, Wolswinkel, Rianne, Petretto, Enrico, Pravenec, Michal, Remme, Carol Ann, Bezzina, Connie R.
Publicado 2018

Systems genetics in the rat HXB/BXH family identifies Tti2 as a pleiotropic quantitative trait gene for adult hippocampal neurogenesis and serum glucose

por Senko, Anna N., Overall, Rupert W., Silhavy, Jan, Mlejnek, Petr, Malínská, Hana, Hüttl, Martina, Marková, Irena, Fabel, Klaus S., Lu, Lu, Stuchlik, Ales, Williams, Robert W., Pravenec, Michal, Kempermann, Gerd
Publicado 2022

Genetic Complementation of ATP Synthase Deficiency Due to Dysfunction of TMEM70 Assembly Factor in Rat

por Marković, Aleksandra, Tauchmannová, Kateřina, Šimáková, Miroslava, Mlejnek, Petr, Kaplanová, Vilma, Pecina, Petr, Pecinová, Alena, Papoušek, František, Liška, František, Šilhavý, Jan, Mikešová, Jana, Neckář, Jan, Houštěk, Josef, Pravenec, Michal, Mráček, Tomáš
Publicado 2022

Translational regulation shapes the molecular landscape of complex disease phenotypes

por Schafer, Sebastian, Adami, Eleonora, Heinig, Matthias, Rodrigues, Katharina E. Costa, Kreuchwig, Franziska, Silhavy, Jan, van Heesch, Sebastiaan, Simaite, Deimante, Rajewsky, Nikolaus, Cuppen, Edwin, Pravenec, Michal, Vingron, Martin, Cook, Stuart A., Hubner, Norbert
Publicado 2015