NACHO: an R package for quality control of NanoString nCounter data

por Canouil, Mickaël, Bouland, Gerard A, Bonnefond, Amélie, Froguel, Philippe, ’t Hart, Leen M, Slieker, Roderick C
Publicado 2019

Assessment of the bi-directional relationship between blood mitochondrial DNA copy number and type 2 diabetes mellitus: a multivariable-adjusted regression and Mendelian randomisat...

por Wang, Wenyi, Luo, Jiao, Willems van Dijk, Ko, Hägg, Sara, Grassmann, Felix, `t Hart, Leen M., van Heemst, Diana, Noordam, Raymond
Publicado 2022

Sex Steroids Affect Triglyceride Handling, Glucose-Dependent Insulinotropic Polypeptide, and Insulin Sensitivity: A 1-week randomized clinical trial in healthy young men

por Lapauw, Bruno, Ouwens, Margriet, ′t Hart, Leen M., Wuyts, Birgitte, Holst, Jens J., T'Sjoen, Guy, Kaufman, Jean-Marc, Ruige, Johannes B.
Publicado 2010

CONQUER: an interactive toolbox to understand functional consequences of GWAS hits

por Bouland, Gerard A, Beulens, Joline W J, Nap, Joey, van der Slik, Arno R, Zaldumbide, Arnaud, ’t Hart, Leen M, Slieker, Roderick C
Publicado 2020

Diabetes risk loci-associated pathways are shared across metabolic tissues

por Bouland, Gerard A., Beulens, Joline W. J., Nap, Joey, van der Slik, Arno R., Zaldumbide, Arnaud, ’t Hart, Leen M., Slieker, Roderick C.
Publicado 2022

Visit-to-visit variability of glycemia and vascular complications: the Hoorn Diabetes Care System cohort

por Slieker, Roderick C., van der Heijden, Amber A. W. H., Nijpels, Giel, Elders, Petra J. M., ’t Hart, Leen M., Beulens, Joline W. J.
Publicado 2019

HbA(1c) is associated with altered expression in blood of cell cycle- and immune response-related genes

por Slieker, Roderick C., van der Heijden, Amber A. W. A., van Leeuwen, Nienke, Mei, Hailiang, Nijpels, Giel, Beulens, Joline W. J., ’t Hart, Leen M.
Publicado 2017

The Hoorn Diabetes Care System (DCS) cohort. A prospective cohort of persons with type 2 diabetes treated in primary care in the Netherlands

por van der Heijden, Amber AWA, Rauh, Simone P, Dekker, Jacqueline M, Beulens, Joline W, Elders, Petra, ‘t Hart, Leen M, Rutters, Femke, van Leeuwen, Nienke, Nijpels, Giel
Publicado 2017

Performance of Risk Assessment Models for Prevalent or Undiagnosed Type 2 Diabetes Mellitus in a Multi-Ethnic Population—The Helius Study

por Obura, Morgan O., van Valkengoed, Irene GM, Rutters, Femke, ’t Hart, Leen M., Rauh, Simone P., Moll van Charante, Eric, Snijder, Marieke B., Beulens, Joline W.J.
Publicado 2021

Altered blood gene expression in the obesity-related type 2 diabetes cluster may be causally involved in lipid metabolism: a Mendelian randomisation study

por de Klerk, Juliette A., Beulens, Joline W. J., Mei, Hailiang, Bijkerk, Roel, van Zonneveld, Anton Jan, Koivula, Robert W., Elders, Petra J. M., ’t Hart, Leen M., Slieker, Roderick C.
Publicado 2023

Apolipoprotein-CIII O-Glycosylation, a Link between GALNT2 and Plasma Lipids

por Naber, Annemieke, Demus, Daniel, Slieker, Roderick, Nicolardi, Simone, Beulens, Joline W. J., Elders, Petra J. M., Lieverse, Aloysius G., Sijbrands, Eric J. G., ’t Hart, Leen M., Wuhrer, Manfred, van Hoek, Mandy
Publicado 2023

Metformin and statin use associate with plasma protein N-glycosylation in people with type 2 diabetes

por Singh, Sunny S, Naber, Annemieke, Dotz, Viktoria, Schoep, Emma, Memarian, Elham, Slieker, Roderick C, Elders, Petra J M, Vreeker, Gerda, Nicolardi, Simone, Wuhrer, Manfred, Sijbrands, Eric J G, Lieverse, Aloysius G, 't Hart, Leen M, van Hoek, Mandy
Publicado 2020

Plasma protein N-glycosylation is associated with cardiovascular disease, nephropathy, and retinopathy in type 2 diabetes

por Memarian, Elham, 't Hart, Leen M, Slieker, Roderick C, Lemmers, Roosmarijn F L, van der Heijden, Amber A, Rutters, Femke, Nijpels, Giel, Schoep, Emma, Lieverse, Aloysius G, Sijbrands, Eric J G, Wuhrer, Manfred, van Hoek, Mandy, Dotz, Viktoria
Publicado 2021

Performance of prediction models for nephropathy in people with type 2 diabetes: systematic review and external validation study

por Slieker, Roderick C, van der Heijden, Amber A W A, Siddiqui, Moneeza K, Langendoen-Gort, Marlous, Nijpels, Giel, Herings, Ron, Feenstra, Talitha L, Moons, Karel G M, Bell, Samira, Elders, Petra J, ’t Hart, Leen M, Beulens, Joline W J
Publicado 2021

A SNP panel for identification of DNA and RNA specimens

por Yousefi, Soheil, Abbassi-Daloii, Tooba, Kraaijenbrink, Thirsa, Vermaat, Martijn, Mei, Hailiang, van ‘t Hof, Peter, van Iterson, Maarten, Zhernakova, Daria V., Claringbould, Annique, Franke, Lude, ‘t Hart, Leen M., Slieker, Roderick C., van der Heijden, Amber, de Knijff, Peter, ’t Hoen, Peter A. C.
Publicado 2018

Discovery of predictors of sudden cardiac arrest in diabetes: rationale and outline of the RESCUED (REcognition of Sudden Cardiac arrest vUlnErability in Diabetes) project

por van Dongen, Laura H, Harms, Peter P, Hoogendoorn, Mark, Zimmerman, Dominic S, Lodder, Elisabeth M, 't Hart, Leen M, Herings, Ron, van Weert, Henk C P M, Nijpels, Giel, Swart, Karin M A, van der Heijden, Amber A, Blom, Marieke T, Elders, Petra J, Tan, Hanno L
Publicado 2021

The endothelial function biomarker soluble E‐selectin is associated with nonalcoholic fatty liver disease

por Simons, Nynke, Bijnen, Mitchell, Wouters, Kristiaan A. M., Rensen, Sander S., Beulens, Joline W. J., van Greevenbroek, Marleen M. J., ’t Hart, Leen M., Greve, Jan Willem M., van der Kallen, Carla J. H., Schaper, Nicolaas C., Schalkwijk, Casper G., Stehouwer, Coen D. A., Brouwers, Martijn C. G. J.
Publicado 2020

Gene Variants in the Novel Type 2 Diabetes Loci CDC123/CAMK1D, THADA, ADAMTS9, BCL11A, and MTNR1B Affect Different Aspects of Pancreatic β-Cell Function

por Simonis-Bik, Annemarie M., Nijpels, Giel, van Haeften, Timon W., Houwing-Duistermaat, Jeanine J., Boomsma, Dorret I., Reiling, Erwin, van Hove, Els C., Diamant, Michaela, Kramer, Mark H.H., Heine, Robert J., Maassen, J. Antonie, Slagboom, P. Eline, Willemsen, Gonneke, Dekker, Jacqueline M., Eekhoff, Elisabeth M., de Geus, Eco J., 't Hart, Leen M.
Publicado 2010

Combined Risk Allele Score of Eight Type 2 Diabetes Genes Is Associated With Reduced First-Phase Glucose-Stimulated Insulin Secretion During Hyperglycemic Clamps

por ‘t Hart, Leen M., Simonis-Bik, Annemarie M., Nijpels, Giel, van Haeften, Timon W., Schäfer, Silke A., Houwing-Duistermaat, Jeanine J., Boomsma, Dorret I., Groenewoud, Marlous J., Reiling, Erwin, van Hove, Els C., Diamant, Michaela, Kramer, Mark H.H., Heine, Robert J., Maassen, J. Antonie, Kirchhoff, Kerstin, Machicao, Fausto, Häring, Hans-Ulrich, Slagboom, P. Eline, Willemsen, Gonneke, Eekhoff, Elisabeth M., de Geus, Eco J., Dekker, Jacqueline M., Fritsche, Andreas
Publicado 2010

Genome-Wide Meta-analysis Identifies Genetic Variants Associated With Glycemic Response to Sulfonylureas

por Dawed, Adem Y., Yee, Sook Wah, Zhou, Kaixin, van Leeuwen, Nienke, Zhang, Yanfei, Siddiqui, Moneeza K., Etheridge, Amy, Innocenti, Federico, Xu, Fei, Li, Josephine H., Beulens, Joline W., van der Heijden, Amber A., Slieker, Roderick C., Chang, Yu-Chuan, Mercader, Josep M., Kaur, Varinderpal, Witte, John S., Lee, Ming Ta Michael, Kamatani, Yoichiro, Momozawa, Yukihide, Kubo, Michiaki, Palmer, Colin N.A., Florez, Jose C., Hedderson, Monique M., ‘t Hart, Leen M., Giacomini, Kathleen M., Pearson, Ewan R.
Publicado 2021