A cell polarity protein aPKCλ is required for eye lens formation and growth

por Sugiyama, Yuki, Akimoto, Kazunori, Robinson, Michael L., Ohno, Shigeo, Quinlan, Roy A.
Publicado 2009

Short term but highly efficient Cas9 expression mediated by excisional system using adenovirus vector and Cre

por Nagamoto, Sayaka, Agawa, Miyuki, Tsuchitani, Emi, Akimoto, Kazunori, Matsushima, Saki Kondo, Kanegae, Yumi
Publicado 2021

Regulation of Asymmetric Division by Atypical Protein Kinase C Influences Early Specification of CD8(+) T Lymphocyte Fates

por Metz, Patrick J., Lopez, Justine, Kim, Stephanie H., Akimoto, Kazunori, Ohno, Shigeo, Chang, John T.
Publicado 2016

Loss of aPKCλ in Differentiated Neurons Disrupts the Polarity Complex but Does Not Induce Obvious Neuronal Loss or Disorientation in Mouse Brains

por Yamanaka, Tomoyuki, Tosaki, Asako, Kurosawa, Masaru, Akimoto, Kazunori, Hirose, Tomonori, Ohno, Shigeo, Hattori, Nobutaka, Nukina, Nobuyuki
Publicado 2013

Association of PSA variability with prostate cancer development using large-scale medical information data: a retrospective cohort study

por Maeda-Minami, Ayako, Nishikawa, Tomoki, Ishikawa, Hideki, Mutoh, Michihiro, Akimoto, Kazunori, Matsuyama, Yutaka, Mano, Yasunari, Uemura, Hiroji
Publicado 2023

Atypical Protein Kinase C Is Involved in the Evolutionarily Conserved Par Protein Complex and Plays a Critical Role in Establishing Epithelia-Specific Junctional Structures

por Suzuki, Atsushi, Yamanaka, Tomoyuki, Hirose, Tomonori, Manabe, Naoyuki, Mizuno, Keiko, Shimizu, Miki, Akimoto, Kazunori, Izumi, Yasushi, Ohnishi, Tetsuo, Ohno, Shigeo
Publicado 2001

An Essential Role of the Universal Polarity Protein, aPKCλ, on the Maintenance of Podocyte Slit Diaphragms

por Hirose, Tomonori, Satoh, Daisuke, Kurihara, Hidetake, Kusaka, Chiho, Hirose, Hiroko, Akimoto, Kazunori, Matsusaka, Taiji, Ichikawa, Iekuni, Noda, Tetsuo, Ohno, Shigeo
Publicado 2009

Nutlin-3a suppresses poly (ADP-ribose) polymerase 1 by mechanisms different from conventional PARP1 suppressors in a human breast cancer cell line

por Kobayashi, Masaki, Ishizaki, Yuka, Owaki, Mika, Matsumoto, Yoko, Kakiyama, Yuri, Hoshino, Shunsuke, Tagawa, Ryoma, Sudo, Yuka, Okita, Naoyuki, Akimoto, Kazunori, Higami, Yoshikazu
Publicado 2020

High expression of SLC20A1 is less effective for endocrine therapy and predicts late recurrence in ER-positive breast cancer

por Onaga, Chotaro, Tamori, Shoma, Matsuoka, Izumi, Ozaki, Ayaka, Motomura, Hitomi, Nagashima, Yuka, Sato, Tsugumichi, Sato, Keiko, Xiong, Yuyun, Sasaki, Kazunori, Ohno, Shigeo, Akimoto, Kazunori
Publicado 2022

Enhanced hepatic differentiation in the subpopulation of human amniotic stem cells under 3D multicellular microenvironment

por Furuya, Kinji, Zheng, Yun-Wen, Sako, Daisuke, Iwasaki, Kenichi, Zheng, Dong-Xu, Ge, Jian-Yun, Liu, Li-Ping, Furuta, Tomoaki, Akimoto, Kazunori, Yagi, Hiroya, Hamada, Hiromi, Isoda, Hiroko, Oda, Tatsuya, Ohkohchi, Nobuhiro
Publicado 2019

Transcriptomic and Functional Evidence Show Similarities between Human Amniotic Epithelial Stem Cells and Keratinocytes

por Liu, Li-Ping, Zheng, Dong-Xu, Xu, Zheng-Fang, Zhou, Hu-Cheng, Wang, Yun-Cong, Zhou, Hang, Ge, Jian-Yun, Sako, Daisuke, Li, Mi, Akimoto, Kazunori, Li, Yu-Mei, Zheng, Yun-Wen
Publicado 2021

High PKCλ expression is required for ALDH1-positive cancer stem cell function and indicates a poor clinical outcome in late-stage breast cancer patients

por Nozaki, Yuka, Motomura, Hitomi, Tamori, Shoma, Kimura, Yumiko, Onaga, Chotaro, Kanai, Shotaro, Ishihara, Yuka, Ozaki, Ayaka, Hara, Yasushi, Harada, Yohsuke, Mano, Yasunari, Sato, Tsugumichi, Sato, Keiko, Sasaki, Kazunori, Ishiguro, Hitoshi, Ohno, Shigeo, Akimoto, Kazunori
Publicado 2020

Correlation between c-Met and ALDH1 contributes to the survival and tumor-sphere formation of ALDH1 positive breast cancer stem cells and predicts poor clinical outcome in breast c...

por Nozaki, Yuka, Tamori, Shoma, Inada, Masahiro, Katayama, Reika, Nakane, Hiromi, Minamishima, Osamu, Onodera, Yuka, Abe, Makoto, Shiina, Shota, Tamura, Kei, Kodama, Daichi, Sato, Keiko, Hara, Yasushi, Abe, Ryo, Takasawa, Ryoko, Yoshimori, Atsushi, Shinomiya, Nariyoshi, Tanuma, Sei-ichi, Akimoto, Kazunori
Publicado 2017

Glyoxalase 1 and protein kinase Cλ as potential therapeutic targets for late-stage breast cancer

por Motomura, Hitomi, Ozaki, Ayaka, Tamori, Shoma, Onaga, Chotaro, Nozaki, Yuka, Waki, Yuko, Takasawa, Ryoko, Yoshizawa, Kazumi, Mano, Yasunari, Sato, Tsugumichi, Sasaki, Kazunori, Ishiguro, Hitoshi, Miyagi, Yohei, Nagashima, Yoji, Yamamoto, Kouji, Sato, Keiko, Hanawa, Takehisa, Tanuma, Sei-Ichi, Ohno, Shigeo, Akimoto, Kazunori
Publicado 2021

Colorectal laterally spreading tumors show characteristic expression of cell polarity factors, including atypical protein kinase C λ/ι, E-cadherin, β-catenin and basement membrane...

por ICHIKAWA, YASUSHI, NAGASHIMA, YOJI, MORIOKA, KAORI, AKIMOTO, KAZUNORI, KOJIMA, YASUYUKI, ISHIKAWA, TAKASHI, GOTO, AYUMU, KOBAYASHI, NORITOSHI, WATANABE, KAZUTERU, OTA, MITSUYOSHI, FUJII, SHOICHI, KAWAMATA, MAYUMI, TAKAGAWA, RYO, KUNIZAKI, CHIKARA, TAKAHASHI, HIROKAZU, NAKAJIMA, ATSUSHI, MAEDA, SHIN, SHIMADA, HIROSHI, INAYAMA, YOSHIAKI, OHNO, SHIGEO, ENDO, ITARU
Publicado 2014

Glyoxalase 1 gene is highly expressed in basal-like human breast cancers and contributes to survival of ALDH1-positive breast cancer stem cells

por Tamori, Shoma, Nozaki, Yuka, Motomura, Hitomi, Nakane, Hiromi, Katayama, Reika, Onaga, Chotaro, Kikuchi, Eriko, Shimada, Nami, Suzuki, Yuhei, Noike, Mei, Hara, Yasushi, Sato, Keiko, Sato, Tsugumichi, Yamamoto, Kouji, Hanawa, Takehisa, Imai, Misa, Abe, Ryo, Yoshimori, Atsushi, Takasawa, Ryoko, Tanuma, Sei-Ichi, Akimoto, Kazunori
Publicado 2018