Subverting lysosomal function in Trypanosoma brucei

por Alsford, Sam
Publicado 2015

Increased Trypanosoma brucei cathepsin-L activity inhibits human serum-mediated trypanolysis

por Alsford, Sam
Publicado 2014

Cell-cycle-regulated control of VSG expression site silencing by histones and histone chaperones ASF1A and CAF-1b in Trypanosoma brucei

por Alsford, Sam, Horn, David
Publicado 2012

DNA breaks as triggers for antigenic variation in African trypanosomes

por Alsford, Sam, Horn, David, Glover, Lucy
Publicado 2009

Genome-wide RNAi screens in African trypanosomes identify the nifurtimox activator NTR and the eflornithine transporter AAT6

por Baker, Nicola, Alsford, Sam, Horn, David
Publicado 2011

DNA Break Site at Fragile Subtelomeres Determines Probability and Mechanism of Antigenic Variation in African Trypanosomes

por Glover, Lucy, Alsford, Sam, Horn, David
Publicado 2013

Deletion of a trypanosome telomere leads to loss of silencing and progressive loss of terminal DNA in the absence of cell cycle arrest

por Glover, Lucy, Alsford, Sam, Beattie, Caroline, Horn, David
Publicado 2007

RNA interference, growth and differentiation appear normal in African trypanosomes lacking Tudor staphylococcal nuclease

por Alsford, Sam, Kemp, Louise E., Kawahara, Taemi, Horn, David
Publicado 2010

Genetic dissection of drug resistance in trypanosomes

por ALSFORD, SAM, KELLY, JOHN M., BAKER, NICOLA, HORN, DAVID
Publicado 2013

Synthetic biology tools for engineering Goodwin oscillation in Trypanosoma brucei brucei

por Borg, Yanika, Alsford, Sam, Pavlika, Vasos, Zaikin, Alexei, Nesbeth, Darren N.
Publicado 2022

Telomeres, tethers and trypanosomes

por Field, Mark C., Horn, David, Alsford, Sam, Koreny, Ludek, Rout, Michael P.
Publicado 2012

Modulation of the Surface Proteome through Multiple Ubiquitylation Pathways in African Trypanosomes

por Zoltner, Martin, Leung, Ka Fai, Alsford, Sam, Horn, David, Field, Mark C.
Publicado 2015

Correction: Modulation of the Surface Proteome through Multiple Ubiquitylation Pathways in African Trypanosomes

por Zoltner, Martin, Leung, Ka Fai, Alsford, Sam, Horn, David, Field, Mark C.
Publicado 2015

Decoding the network of Trypanosoma brucei proteins that determines sensitivity to apolipoprotein-L1

por Currier, Rachel B., Cooper, Anneli, Burrell-Saward, Hollie, MacLeod, Annette, Alsford, Sam
Publicado 2018

Antigenic variation in African trypanosomes: the importance of chromosomal and nuclear context in VSG expression control

por Glover, Lucy, Hutchinson, Sebastian, Alsford, Sam, McCulloch, Richard, Field, Mark C, Horn, David
Publicado 2013

Cathepsin-L Can Resist Lysis by Human Serum in Trypanosoma brucei brucei

por Alsford, Sam, Currier, Rachel B., Guerra-Assunção, José Afonso, Clark, Taane G., Horn, David
Publicado 2014

Ornithine uptake and the modulation of drug sensitivity in Trypanosoma brucei

por Macedo, Juan P., Currier, Rachel B., Wirdnam, Corina, Horn, David, Alsford, Sam, Rentsch, Doris
Publicado 2017

Two essential MYST-family proteins display distinct roles in histone H4K10 acetylation and telomeric silencing in trypanosomes

por Kawahara, Taemi, Siegel, T Nicolai, Ingram, Alexandra K, Alsford, Sam, Cross, George A M, Horn, David
Publicado 2008

Insights into antitrypanosomal drug mode-of-action from cytology-based profiling

por Thomas, James A., Baker, Nicola, Hutchinson, Sebastian, Dominicus, Caia, Trenaman, Anna, Glover, Lucy, Alsford, Sam, Horn, David
Publicado 2018

Distinct activation mechanisms trigger the trypanocidal activity of DNA damaging prodrugs

por Meredith, Emma Louise, Kumar, Ambika, Konno, Aya, Szular, Joanna, Alsford, Sam, Seifert, Karin, Horn, David, Wilkinson, Shane R.
Publicado 2017