RAS and PP2A activities converge on epigenetic gene regulation

por Aakula, Anna, Sharma, Mukund, Tabaro, Francesco, Nätkin, Reetta, Kamila, Jesse, Honkanen, Henrik, Schapira, Matthieu, Arrowsmith, Cheryl, Nykter, Matti, Westermarck, Jukka
Publicado 2023

PP2A methylesterase PME‐1 suppresses anoikis and is associated with therapy relapse of PTEN ‐deficient prostate cancers

por Aakula, Anna, Isomursu, Aleksi, Rupp, Christian, Erickson, Andrew, Gupta, Nikhil, Kauko, Otto, Shah, Pragya, Padzik, Artur, Pokharel, Yuba Raj, Kaur, Amanpreet, Li, Song‐Ping, Trotman, Lloyd, Taimen, Pekka, Rannikko, Antti, Lammerding, Jan, Paatero, Ilkka, Mirtti, Tuomas, Ivaska, Johanna, Westermarck, Jukka
Publicado 2023

Structural mechanism for inhibition of PP2A-B56α and oncogenicity by CIP2A

por Pavic, Karolina, Gupta, Nikhil, Omella, Judit Domènech, Derua, Rita, Aakula, Anna, Huhtaniemi, Riikka, Määttä, Juha A., Höfflin, Nico, Okkeri, Juha, Wang, Zhizhi, Kauko, Otto, Varjus, Roosa, Honkanen, Henrik, Abankwa, Daniel, Köhn, Maja, Hytönen, Vesa P., Xu, Wenqing, Nilsson, Jakob, Page, Rebecca, Janssens, Veerle, Leitner, Alexander, Westermarck, Jukka
Publicado 2023