Depletion of CD40 on CD11c(+) cells worsens the metabolic syndrome and ameliorates hepatic inflammation during NASH

por Aarts, Suzanne, Reiche, Myrthe, den Toom, Myrthe, Gijbels, Marion, Beckers, Linda, Gerdes, Norbert, Lutgens, Esther
Publicado 2019

The CD40–CD40L Dyad in Experimental Autoimmune Encephalomyelitis and Multiple Sclerosis

por Aarts, Suzanne A. B. M., Seijkens, Tom T. P., van Dorst, Koos J. F., Dijkstra, Christine D., Kooij, Gijs, Lutgens, Esther
Publicado 2017

Deficiency of T cell CD40L has minor beneficial effects on obesity-induced metabolic dysfunction

por Reiche, Myrthe E, den Toom, Myrthe, Willemsen, Lisa, van Os, Bram, Gijbels, Marion J J, Gerdes, Norbert, Aarts, Suzanne A B M, Lutgens, Esther
Publicado 2019

Macrophage CD40 plays a minor role in obesity-induced metabolic dysfunction

por Aarts, Suzanne A. B. M., Reiche, Myrthe E., den Toom, Myrthe, Beckers, Linda, Gijbels, Marion J. J., Gerdes, Norbert, de Winther, Menno P. J., Lutgens, Esther
Publicado 2018

Macrophage CD40 signaling drives experimental autoimmune encephalomyelitis

por Aarts, Suzanne ABM, Seijkens, Tom TP, Kusters, Pascal JH, van Tiel, Claudia M, Reiche, Myrthe E, den Toom, Myrthe, Beckers, Linda, van Roomen, Cindy PAA, de Winther, Menno PJ, Kooij, Gijs, Lutgens, Esther
Publicado 2019

Adipocytes control hematopoiesis and inflammation through CD40 signaling

por Reiche, Myrthe E., Poels, Kikkie, Bosmans, Laura A., Vos, Winnie G., van Tiel, Claudia M., Gijbels, Marion J.J., Aarts, Suzanne A.B.M., den Toom, Myrthe, Beckers, Linda, Weber, Christian, Atzler, Dorothee, Rensen, Patrick C.N., Kooijman, Sander, Lutgens, Esther
Publicado 2022

Inhibition of CD40-TRAF6 interactions by the small molecule inhibitor 6877002 reduces neuroinflammation

por Aarts, Suzanne A. B. M., Seijkens, Tom T. P., Kusters, Pascal J. H., van der Pol, Susanne M. A., Zarzycka, Barbara, Heijnen, Priscilla D. A. M., Beckers, Linda, den Toom, Myrthe, Gijbels, Marion J. J., Boon, Louis, Weber, Christian, de Vries, Helga E., Nicolaes, Gerry A. F., Dijkstra, Christine D., Kooij, Gijs, Lutgens, Esther
Publicado 2017

Myeloid CD40 deficiency reduces atherosclerosis by impairing macrophages’ transition into a pro-inflammatory state

por Bosmans, Laura A, van Tiel, Claudia M, Aarts, Suzanne A B M, Willemsen, Lisa, Baardman, Jeroen, van Os, Bram W, den Toom, Myrthe, Beckers, Linda, Ahern, David J, Levels, Johannes H M, Jongejan, Aldo, Moerland, Perry D, Verberk, Sanne G S, van den Bossche, Jan, de Winther, Menno M P J, Weber, Christian, Atzler, Dorothee, Monaco, Claudia, Gerdes, Norbert, Shami, Annelie, Lutgens, Esther
Publicado 2022

Nicotinamide riboside supplementation alters body composition and skeletal muscle acetylcarnitine concentrations in healthy obese humans

por Remie, Carlijn M E, Roumans, Kay H M, Moonen, Michiel P B, Connell, Niels J, Havekes, Bas, Mevenkamp, Julian, Lindeboom, Lucas, de Wit, Vera H W, van de Weijer, Tineke, Aarts, Suzanne A B M, Lutgens, Esther, Schomakers, Bauke V, Elfrink, Hyung L, Zapata-Pérez, Rubén, Houtkooper, Riekelt H, Auwerx, Johan, Hoeks, Joris, Schrauwen-Hinderling, Vera B, Phielix, Esther, Schrauwen, Patrick
Publicado 2020

Targeting CD40-Induced TRAF6 Signaling in Macrophages Reduces Atherosclerosis

por Seijkens, Tom T.P., van Tiel, Claudia M., Kusters, Pascal J.H., Atzler, Dorothee, Soehnlein, Oliver, Zarzycka, Barbara, Aarts, Suzanne A.B.M., Lameijer, Marnix, Gijbels, Marion J., Beckers, Linda, den Toom, Myrthe, Slütter, Bram, Kuiper, Johan, Duchene, Johan, Aslani, Maria, Megens, Remco T.A., van ‘t Veer, Cornelis, Kooij, Gijs, Schrijver, Roy, Hoeksema, Marten A., Boon, Louis, Fay, Francois, Tang, Jun, Baxter, Samantha, Jongejan, Aldo, Moerland, Perry D., Vriend, Gert, Bleijlevens, Boris, Fisher, Edward A., Duivenvoorden, Raphael, Gerdes, Norbert, de Winther, Menno P.J., Nicolaes, Gerry A., Mulder, Willem J.M., Weber, Christian, Lutgens, Esther
Publicado 2018