The Intriguing Sigma-1 and Sigma-2 Receptors and Their Potential Therapeutic Roles 2.0

द्वारा Abate, Carmen, Maurice, Tangui
प्रकाशित 2023

σ(2) Receptor and Its Role in Cancer with Focus on a MultiTarget Directed Ligand (MTDL) Approach

द्वारा Abatematteo, Francesca Serena, Niso, Mauro, Lacivita, Enza, Abate, Carmen
प्रकाशित 2021

Multi-Target Directed Ligands (MTDLs) Binding the σ(1) Receptor as Promising Therapeutics: State of the Art and Perspectives

द्वारा Abatematteo, Francesca Serena, Niso, Mauro, Contino, Marialessandra, Leopoldo, Marcello, Abate, Carmen
प्रकाशित 2021

Multifunctional thiosemicarbazones targeting sigma receptors: in vitro and in vivo antitumor activities in pancreatic cancer models

द्वारा Niso, Mauro, Kopecka, Joanna, Abatematteo, Francesca Serena, Berardi, Francesco, Riganti, Chiara, Abate, Carmen
प्रकाशित 2021

PB28, the Sigma-1 and Sigma-2 Receptors Modulator With Potent Anti–SARS-CoV-2 Activity: A Review About Its Pharmacological Properties and Structure Affinity Relationships

द्वारा Abate, Carmen, Niso, Mauro, Abatematteo, Francesca Serena, Contino, Marialessandra, Colabufo, Nicola Antonio, Berardi, Francesco
प्रकाशित 2020

MRP1-Collateral Sensitizers as a Novel Therapeutic Approach in Resistant Cancer Therapy: An In Vitro and In Vivo Study in Lung Resistant Tumor

द्वारा Riganti, Chiara, Giampietro, Roberta, Kopecka, Joanna, Costamagna, Costanzo, Abatematteo, Francesca Serena, Contino, Marialessandra, Abate, Carmen
प्रकाशित 2020

Sigma-2 receptor agonist derivatives of 1-Cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28) induce cell death via mitochondrial superoxide produ...

द्वारा Pati, Maria Laura, Hornick, John R., Niso, Mauro, Berardi, Francesco, Spitzer, Dirk, Abate, Carmen, Hawkins, William
प्रकाशित 2017

Cytotoxic pathways activated by multifunctional thiosemicarbazones targeting sigma-2 receptors in breast and lung carcinoma cells

द्वारा Kopecka, Joanna, Barbanente, Alessandra, Vitone, Daniele, Arnesano, Fabio, Margiotta, Nicola, Berchialla, Paola, Niso, Mauro, Riganti, Chiara, Abate, Carmen
प्रकाशित 2023

NO1, a New Sigma 2 Receptor/TMEM97 Fluorescent Ligand, Downregulates SOCE and Promotes Apoptosis in the Triple Negative Breast Cancer Cell Lines

द्वारा Cantonero, Carlos, Camello, Pedro Javier, Abate, Carmen, Berardi, Francesco, Salido, Gines Maria, Rosado, Juan Antonio, Redondo, Pedro C.
प्रकाशित 2020

Design and Synthesis of Arylpiperazine Serotonergic/Dopaminergic Ligands with Neuroprotective Properties

द्वारा Mastromarino, Margherita, Niso, Mauro, Abate, Carmen, Proschak, Ewgenij, Dubiel, Mariam, Stark, Holger, Castro, Marián, Lacivita, Enza, Leopoldo, Marcello
प्रकाशित 2022

Lysosomal Membrane Permeabilization is an Early Event in Sigma-2 Receptor Ligand Mediated Cell Death in Pancreatic Cancer

द्वारा Hornick, John R, Vangveravong, Suwanna, Spitzer, Dirk, Abate, Carmen, Berardi, Francesco, Goedegebuure, Peter, Mach, Robert H, Hawkins, William G
प्रकाशित 2012

Why PB28 Could Be a Covid 2019 Game Changer?

द्वारा Colabufo, Nicola Antonio, Leopoldo, Marcello, Ferorelli, Savina, Abate, Carmen, Contino, Marialessandra, Perrone, Maria Grazia, Niso, Mauro, Perrone, Roberto, Berardi, Francesco
प्रकाशित 2020

New Pharmacological Strategies against Pancreatic Adenocarcinoma: The Multifunctional Thiosemicarbazone FA4

द्वारा Anobile, Dario P., Niso, Mauro, Puerta, Adrian, Fraga Rodrigues, Stephanie M., Abatematteo, Francesca S., Avan, Amir, Abate, Carmen, Riganti, Chiara, Giovannetti, Elisa
प्रकाशित 2022

Sigma-2 receptor/TMEM97 agonist PB221 as an alternative drug for brain tumor

द्वारा Liu, Chia-Chi, Yu, Ching-Fang, Wang, Shu-Chi, Li, Hsueh-Yin, Lin, Chiu-Min, Wang, Hsia-Han, Abate, Carmen, Chiang, Chi-Shiun
प्रकाशित 2019

Development of Fluorescent 4-[4-(3H-Spiro[isobenzofuran-1,4′-piperidin]-1′-yl)butyl]indolyl Derivatives as High-Affinity Probes to Enable the Study of σ Receptors via Fluorescence-...

द्वारा Abatematteo, Francesca Serena, Majellaro, Maria, Montsch, Bianca, Prieto-Díaz, Rubén, Niso, Mauro, Contino, Marialessandra, Stefanachi, Angela, Riganti, Chiara, Mangiatordi, Giuseppe Felice, Delre, Pietro, Heffeter, Petra, Sotelo, Eddy, Abate, Carmen
प्रकाशित 2023

A conformational rearrangement of the SARS-CoV-2 host protein sigma-1 is required for antiviral activity: insights from a combined in-silico/in-vitro approach

द्वारा Abatematteo, Francesca Serena, Delre, Pietro, Mercurio, Ivan, Rezelj, Veronica V., Siliqi, Dritan, Beaucourt, Stephanie, Lattanzi, Gianluca, Colabufo, Nicola Antonio, Leopoldo, Marcello, Saviano, Michele, Vignuzzi, Marco, Mangiatordi, Giuseppe Felice, Abate, Carmen
प्रकाशित 2023

Proceedings from the Fourth International Symposium on σ-2 Receptors: Role in Health and Disease

द्वारा Izzo, Nicholas J., Colom-Cadena, Martí, Riad, Aladdin A., Xu, Jinbin, Singh, Meharvan, Abate, Carmen, Cahill, Michael A., Spires-Jones, Tara L., Bowen, Wayne D., Mach, Robert H., Catalano, Susan M.
प्रकाशित 2020

Sigma-2 Receptor Ligand Binding Modulates Association between TSPO and TMEM97

द्वारा Thejer, Bashar M., Infantino, Vittoria, Santarsiero, Anna, Pappalardo, Ilaria, Abatematteo, Francesca S., Teakel, Sarah, Van Oosterum, Ashleigh, Mach, Robert H., Denora, Nunzio, Lee, Byung Chul, Resta, Nicoletta, Bagnulo, Rosanna, Niso, Mauro, Contino, Marialessandra, Montsch, Bianca, Heffeter, Petra, Abate, Carmen, Cahill, Michael A.
प्रकाशित 2023

Synthesis and Biological Evaluation of Enantiomerically Pure (R)- and (S)-[(18)F]OF-NB1 for Imaging the GluN2B Subunit-Containing NMDA receptors

द्वारा Korff, Marvin, Chaudhary, Ahmad, Li, Yinlong, Zhou, Xin, Zhao, Chunyu, Rong, Jian, Chen, Jiahui, Xiao, Zhiwei, Elghazawy, Nehal H., Sippl, Wolfgang, Davenport, April T., Daunais, James B., Wang, Lu, Abate, Carmen, Ahmed, Hazem, Crowe, Ron, Liang, Steven H., Ametamey, Simon M., Wünsch, Bernhard, Haider, Ahmed
प्रकाशित 2023

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms

द्वारा Gordon, David E., Hiatt, Joseph, Bouhaddou, Mehdi, Rezelj, Veronica V., Ulferts, Svenja, Braberg, Hannes, Jureka, Alexander S., Obernier, Kirsten, Guo, Jeffrey Z., Batra, Jyoti, Kaake, Robyn M., Weckstein, Andrew R., Owens, Tristan W., Gupta, Meghna, Pourmal, Sergei, Titus, Erron W., Cakir, Merve, Soucheray, Margaret, McGregor, Michael, Cakir, Zeynep, Jang, Gwendolyn, O’Meara, Matthew J., Tummino, Tia A., Zhang, Ziyang, Foussard, Helene, Rojc, Ajda, Zhou, Yuan, Kuchenov, Dmitry, Hüttenhain, Ruth, Xu, Jiewei, Eckhardt, Manon, Swaney, Danielle L., Fabius, Jacqueline M., Ummadi, Manisha, Tutuncuoglu, Beril, Rathore, Ujjwal, Modak, Maya, Haas, Paige, Haas, Kelsey M., Naing, Zun Zar Chi, Pulido, Ernst H., Shi, Ying, Barrio-Hernandez, Inigo, Memon, Danish, Petsalaki, Eirini, Dunham, Alistair, Marrero, Miguel Correa, Burke, David, Koh, Cassandra, Vallet, Thomas, Silvas, Jesus A., Azumaya, Caleigh M., Billesbølle, Christian, Brilot, Axel F., Campbell, Melody G., Diallo, Amy, Dickinson, Miles Sasha, Diwanji, Devan, Herrera, Nadia, Hoppe, Nick, Kratochvil, Huong T., Liu, Yanxin, Merz, Gregory E., Moritz, Michelle, Nguyen, Henry C., Nowotny, Carlos, Puchades, Cristina, Rizo, Alexandrea N., Schulze-Gahmen, Ursula, Smith, Amber M., Sun, Ming, Young, Iris D., Zhao, Jianhua, Asarnow, Daniel, Biel, Justin, Bowen, Alisa, Braxton, Julian R., Chen, Jen, Chio, Cynthia M., Chio, Un Seng, Deshpande, Ishan, Doan, Loan, Faust, Bryan, Flores, Sebastian, Jin, Mingliang, Kim, Kate, Lam, Victor L., Li, Fei, Li, Junrui, Li, Yen-Li, Li, Yang, Liu, Xi, Lo, Megan, Lopez, Kyle E., Melo, Arthur A., Moss, Frank R., Nguyen, Phuong, Paulino, Joana, Pawar, Komal Ishwar, Peters, Jessica K., Pospiech, Thomas H., Safari, Maliheh, Sangwan, Smriti, Schaefer, Kaitlin, Thomas, Paul V., Thwin, Aye C., Trenker, Raphael, Tse, Eric, Tsui, Tsz Kin Martin, Wang, Feng, Whitis, Natalie, Yu, Zanlin, Zhang, Kaihua, Zhang, Yang, Zhou, Fengbo, Saltzberg, Daniel, Hodder, Anthony J., Shun-Shion, Amber S., Williams, Daniel M., White, Kris M., Rosales, Romel, Kehrer, Thomas, Miorin, Lisa, Moreno, Elena, Patel, Arvind H., Rihn, Suzannah, Khalid, Mir M., Vallejo-Gracia, Albert, Fozouni, Parinaz, Simoneau, Camille R., Roth, Theodore L., Wu, David, Karim, Mohd Anisul, Ghoussaini, Maya, Dunham, Ian, Berardi, Francesco, Weigang, Sebastian, Chazal, Maxime, Park, Jisoo, Logue, James, McGrath, Marisa, Weston, Stuart, Haupt, Robert, Hastie, C. James, Elliott, Matthew, Brown, Fiona, Burness, Kerry A., Reid, Elaine, Dorward, Mark, Johnson, Clare, Wilkinson, Stuart G., Geyer, Anna, Giesel, Daniel M., Baillie, Carla, Raggett, Samantha, Leech, Hannah, Toth, Rachel, Goodman, Nicola, Keough, Kathleen C., Lind, Abigail L., Klesh, Reyna J., Hemphill, Kafi R., Carlson-Stevermer, Jared, Oki, Jennifer, Holden, Kevin, Maures, Travis, Pollard, Katherine S., Sali, Andrej, Agard, David A., Cheng, Yifan, Fraser, James S., Frost, Adam, Jura, Natalia, Kortemme, Tanja, Manglik, Aashish, Southworth, Daniel R., Stroud, Robert M., Alessi, Dario R., Davies, Paul, Frieman, Matthew B., Ideker, Trey, Abate, Carmen, Jouvenet, Nolwenn, Kochs, Georg, Shoichet, Brian, Ott, Melanie, Palmarini, Massimo, Shokat, Kevan M., García-Sastre, Adolfo, Rassen, Jeremy A., Grosse, Robert, Rosenberg, Oren S., Verba, Kliment A., Basler, Christopher F., Vignuzzi, Marco, Peden, Andrew A., Beltrao, Pedro, Krogan, Nevan J.
प्रकाशित 2020