Gasdermin E permits interleukin-1 beta release in distinct sublytic and pyroptotic phases

por Zhou, Bowen, Abbott, Derek W.
Publicado 2021

Protein engineering reveals that gasdermin A preferentially targets mitochondrial membranes over the plasma membrane during pyroptosis

por Kondolf, Hannah C., D'Orlando, Dana A., Dubyak, George R., Abbott, Derek W.
Publicado 2023

Structure shows that the BIR2 domain of E3 ligase XIAP binds across the RIPK2 kinase dimer interface

por Lethier, Mathilde, Huard, Karine, Hons, Michael, Favier, Adrien, Brutscher, Bernhard, Boeri Erba, Elisabetta, Abbott, Derek W, Cusack, Stephen, Pellegrini, Erika
Publicado 2023

ABIN-1 Regulates RIPK1 Activation by Bridging M1 ubiquitination with K63 Deubiquitination in TNF-RSC

por Dziedzic, Slawomir A., Su, Zhenyi, Barrett, Vica Jean, Najafov, Ayaz, Mookhitiar, Adnan K., Amin, Palak, Pan, Heling, Sun, Li, Zhu, Hong, Ma, Averil, Abbott, Derek W., Yuan, Junying
Publicado 2017

N-GSDMD trafficking to neutrophil organelles facilitates IL-1β release independently of plasma membrane pores and pyroptosis

por Karmakar, Mausita, Minns, Martin, Greenberg, Elyse N., Diaz-Aponte, Jose, Pestonjamasp, Kersi, Johnson, Jennifer L., Rathkey, Joseph K., Abbott, Derek W., Wang, Kun, Shao, Feng, Catz, Sergio D., Dubyak, George R., Pearlman, Eric
Publicado 2020

TH17 cells promote CNS inflammation by sensing danger signals via Mincle

por Zhang, Quanri, Liu, Weiwei, Wang, Han, Zhou, Hao, Bulek, Katarzyna, Chen, Xing, Zhang, Cun-Jin, Zhao, Junjie, Zhang, Renliang, Liu, Caini, Kang, Zizhen, Bermel, Robert A., Dubyak, George, Abbott, Derek W., Xiao, Tsan Sam, Nagy, Laura E., Li, Xiaoxia
Publicado 2022