Tuberin regulates reactive oxygen species in renal proximal cells, kidney from rodents, and kidney from patients with tuberous sclerosis complex

por Habib, Samy L., Abboud, Hanna E.
Publicado 2016

Tuberin haploinsufficiency is associated with the loss of OGG1 in rat kidney tumors

por Habib, Samy L, Simone, Simona, Barnes, Jeff J, Abboud, Hanna E
Publicado 2008

The Informed Consent Process in Genetic Family Studies

por Panoyan, Lucy, Lee, Shuko, Arar, Rawan, Abboud, Hanna E, Arar, Nedal
Publicado 2008

Mechanism of Oxidative DNA Damage in Diabetes : Tuberin Inactivation and Downregulation of DNA Repair Enzyme 8-Oxo-7,8-Dihydro-2′-Deoxyguanosine-DNA Glycosylase

por Simone, Simona, Gorin, Yves, Velagapudi, Chakradhar, Abboud, Hanna E., Habib, Samy L.
Publicado 2008

Evaluation of Neurotrophic Tyrosine Receptor Kinase 2 (NTRK2) as a positional candidate gene for variation in estimated Glomerular Filtration Rate (eGFR) in Mexican American partic...

por Thameem, Farook, Voruganti, V Saroja, Blangero, John, Comuzzie, Anthony G, Abboud, Hanna E
Publicado 2015

TGFβ-Induced Deptor Suppression Recruits mTORC1 and Not mTORC2 to Enhance Collagen I (α2) Gene Expression

por Das, Falguni, Bera, Amit, Ghosh-Choudhury, Nandini, Abboud, Hanna E., Kasinath, Balakuntalam S., Choudhury, Goutam Ghosh
Publicado 2014

Interplay between RNA-binding protein HuR and Nox4 as a novel therapeutic target in diabetic kidney disease

por Shi, Qian, Lee, Doug-Yoon, Féliers, Denis, Abboud, Hanna E., Bhat, Manzoor A., Gorin, Yves
Publicado 2020

Mechanisms of Podocyte Injury in Diabetes: Role of Cytochrome P450 and NADPH Oxidases

por Eid, Assaad A., Gorin, Yves, Fagg, Bridget M., Maalouf, Rita, Barnes, Jeffrey L., Block, Karen, Abboud, Hanna E.
Publicado 2009

Diabetic nephropathy among Mexican Americans

por Debnath, Subrata, Thameem, Farook, Alves, Tahira, Nolen, Jacqueline, Al-Shahrouri, Hania, Bansal, Shweta, Abboud, Hanna E., Fanti, Paolo
Publicado 2012

Tryptophan Metabolism in Patients With Chronic Kidney Disease Secondary to Type 2 Diabetes: Relationship to Inflammatory Markers

por Debnath, Subrata, Velagapudi, Chakradhar, Redus, Laney, Thameem, Farook, Kasinath, Balakuntalam, Hura, Claudia E, Lorenzo, Carlos, Abboud, Hanna E, O’Connor, Jason C
Publicado 2017

Nox4 is a Target for Tuberin Deficiency Syndrome

por Shi, Qian, Viswanadhapalli, Suryavathi, Friedrichs, William E., Velagapudi, Chakradhar, Szyndralewiez, Cédric, Bansal, Shweta, Bhat, Manzoor A., Choudhury, Goutam Ghosh, Abboud, Hanna E.
Publicado 2018

microRNA-21 Governs TORC1 Activation in Renal Cancer Cell Proliferation and Invasion

por Dey, Nirmalya, Das, Falguni, Ghosh-Choudhury, Nandini, Mandal, Chandi Charan, Parekh, Dipen J., Block, Karen, Kasinath, Balakuntalam S., Abboud, Hanna E., Choudhury, Goutam Ghosh
Publicado 2012

Mammalian Target of Rapamycin Regulates Nox4-Mediated Podocyte Depletion in Diabetic Renal Injury

por Eid, Assaad A., Ford, Bridget M., Bhandary, Basant, de Cassia Cavaglieri, Rita, Block, Karen, Barnes, Jeffrey L., Gorin, Yves, Choudhury, Goutam Ghosh, Abboud, Hanna E.
Publicado 2013

The Gly(972)Arg Variant of Human IRS1 Gene Is Associated With Variation in Glomerular Filtration Rate Likely Through Impaired Insulin Receptor Signaling

por Thameem, Farook, Puppala, Sobha, Schneider, Jennifer, Bhandari, Basant, Arya, Rector, Arar, Nedal H., Vasylyeva, Tetyana L., Farook, Vidya S., Fowler, Sharon, Almasy, Laura, Blangero, John, Duggirala, Ravindranath, Abboud, Hanna E.
Publicado 2012

Genome-wide association analysis confirms and extends the association of SLC2A9 with serum uric acid levels to Mexican Americans

por Voruganti, Venkata Saroja, Kent, Jack W., Debnath, Subrata, Cole, Shelley A., Haack, Karin, Göring, Harald H. H., Carless, Melanie A., Curran, Joanne E., Johnson, Matthew P., Almasy, Laura, Dyer, Thomas D., MacCluer, Jean W., Moses, Eric K., Abboud, Hanna E., Mahaney, Michael C., Blangero, John, Comuzzie, Anthony G.
Publicado 2013

A Genome-Wide Search for Linkage of Estimated Glomerular Filtration Rate (eGFR) in the Family Investigation of Nephropathy and Diabetes (FIND)

por Thameem, Farook, Igo, Robert P., Freedman, Barry I., Langefeld, Carl, Hanson, Robert L., Schelling, Jeffrey R., Elston, Robert C., Duggirala, Ravindranath, Nicholas, Susanne B., Goddard, Katrina A. B., Divers, Jasmin, Guo, Xiuqing, Ipp, Eli, Kimmel, Paul L., Meoni, Lucy A., Shah, Vallabh O., Smith, Michael W., Winkler, Cheryl A., Zager, Philip G., Knowler, William C., Nelson, Robert G., Pahl, Madeline V., Parekh, Rulan S., Kao, W. H. Linda, Rasooly, Rebekah S., Adler, Sharon G., Abboud, Hanna E., Iyengar, Sudha K., Sedor, John R.
Publicado 2013

Selecting SNPs informative for African, American Indian and European Ancestry: application to the Family Investigation of Nephropathy and Diabetes (FIND)

por Williams, Robert C., Elston, Robert C., Kumar, Pankaj, Knowler, William C., Abboud, Hanna E., Adler, Sharon, Bowden, Donald W., Divers, Jasmin, Freedman, Barry I., Igo, Robert P., Ipp, Eli, Iyengar, Sudha K., Kimmel, Paul L., Klag, Michael J., Kohn, Orly, Langefeld, Carl D., Leehey, David J., Nelson, Robert G., Nicholas, Susanne B., Pahl, Madeleine V., Parekh, Rulan S., Rotter, Jerome I., Schelling, Jeffrey R., Sedor, John R., Shah, Vallabh O., Smith, Michael W., Taylor, Kent D., Thameem, Farook, Thornley-Brown, Denyse, Winkler, Cheryl A., Guo, Xiuqing, Zager, Phillip, Hanson, Robert L.
Publicado 2016

Genome-Wide Association and Trans-ethnic Meta-Analysis for Advanced Diabetic Kidney Disease: Family Investigation of Nephropathy and Diabetes (FIND)

por Iyengar, Sudha K., Sedor, John R., Freedman, Barry I., Kao, W. H. Linda, Kretzler, Matthias, Keller, Benjamin J., Abboud, Hanna E., Adler, Sharon G., Best, Lyle G., Bowden, Donald W., Burlock, Allison, Chen, Yii-Der Ida, Cole, Shelley A., Comeau, Mary E., Curtis, Jeffrey M., Divers, Jasmin, Drechsler, Christiane, Duggirala, Ravi, Elston, Robert C., Guo, Xiuqing, Huang, Huateng, Hoffmann, Michael Marcus, Howard, Barbara V., Ipp, Eli, Kimmel, Paul L., Klag, Michael J., Knowler, William C., Kohn, Orly F., Leak, Tennille S., Leehey, David J., Li, Man, Malhotra, Alka, März, Winfried, Nair, Viji, Nelson, Robert G., Nicholas, Susanne B., O’Brien, Stephen J., Pahl, Madeleine V., Parekh, Rulan S., Pezzolesi, Marcus G., Rasooly, Rebekah S., Rotimi, Charles N., Rotter, Jerome I., Schelling, Jeffrey R., Seldin, Michael F., Shah, Vallabh O., Smiles, Adam M., Smith, Michael W., Taylor, Kent D., Thameem, Farook, Thornley-Brown, Denyse P., Truitt, Barbara J., Wanner, Christoph, Weil, E. Jennifer, Winkler, Cheryl A., Zager, Philip G., Igo, Robert P., Hanson, Robert L., Langefeld, Carl D.
Publicado 2015

A Loss-of-Function Splice Acceptor Variant in IGF2 Is Protective for Type 2 Diabetes

por Mercader, Josep M., Liao, Rachel G., Bell, Avery D., Dymek, Zachary, Estrada, Karol, Tukiainen, Taru, Huerta-Chagoya, Alicia, Moreno-Macías, Hortensia, Jablonski, Kathleen A., Hanson, Robert L., Walford, Geoffrey A., Moran, Ignasi, Chen, Ling, Agarwala, Vineeta, Ordoñez-Sánchez, María Luisa, Rodríguez-Guillen, Rosario, Rodríguez-Torres, Maribel, Segura-Kato, Yayoi, García-Ortiz, Humberto, Centeno-Cruz, Federico, Barajas-Olmos, Francisco, Caulkins, Lizz, Puppala, Sobha, Fontanillas, Pierre, Williams, Amy L., Bonàs-Guarch, Sílvia, Hartl, Chris, Ripke, Stephan, Tooley, Katherine, Lane, Jacqueline, Zerrweck, Carlos, Martínez-Hernández, Angélica, Córdova, Emilio J., Mendoza-Caamal, Elvia, Contreras-Cubas, Cecilia, González-Villalpando, María E., Cruz-Bautista, Ivette, Muñoz-Hernández, Liliana, Gómez-Velasco, Donaji, Alvirde, Ulises, Henderson, Brian E., Wilkens, Lynne R., Le Marchand, Loic, Arellano-Campos, Olimpia, Riba, Laura, Harden, Maegan, Gabriel, Stacey, Abboud, Hanna E., Cortes, Maria L., Revilla-Monsalve, Cristina, Islas-Andrade, Sergio, Soberon, Xavier, Curran, Joanne E., Jenkinson, Christopher P., DeFronzo, Ralph A., Lehman, Donna M., Hanis, Craig L., Bell, Graeme I., Boehnke, Michael, Blangero, John, Duggirala, Ravindranath, Saxena, Richa, MacArthur, Daniel, Ferrer, Jorge, McCarroll, Steven A., Torrents, David, Knowler, William C., Baier, Leslie J., Burtt, Noel, González-Villalpando, Clicerio, Haiman, Christopher A., Aguilar-Salinas, Carlos A., Tusié-Luna, Teresa, Flannick, Jason, Jacobs, Suzanne B.R., Orozco, Lorena, Altshuler, David, Florez, Jose C.
Publicado 2017

The genetic architecture of type 2 diabetes

por Fuchsberger, Christian, Flannick, Jason, Teslovich, Tanya M, Mahajan, Anubha, Agarwala, Vineeta, Gaulton, Kyle J, Ma, Clement, Fontanillas, Pierre, Moutsianas, Loukas, McCarthy, Davis J, Rivas, Manuel A, Perry, John R B, Sim, Xueling, Blackwell, Thomas W, Robertson, Neil R, Rayner, N William, Cingolani, Pablo, Locke, Adam E, Tajes, Juan Fernandez, Highland, Heather M, Dupuis, Josee, Chines, Peter S, Lindgren, Cecilia M, Hartl, Christopher, Jackson, Anne U, Chen, Han, Huyghe, Jeroen R, van de Bunt, Martijn, Pearson, Richard D, Kumar, Ashish, Müller-Nurasyid, Martina, Grarup, Niels, Stringham, Heather M, Gamazon, Eric R, Lee, Jaehoon, Chen, Yuhui, Scott, Robert A, Below, Jennifer E, Chen, Peng, Huang, Jinyan, Go, Min Jin, Stitzel, Michael L, Pasko, Dorota, Parker, Stephen C J, Varga, Tibor V, Green, Todd, Beer, Nicola L, Day-Williams, Aaron G, Ferreira, Teresa, Fingerlin, Tasha, Horikoshi, Momoko, Hu, Cheng, Huh, Iksoo, Ikram, Mohammad Kamran, Kim, Bong-Jo, Kim, Yongkang, Kim, Young Jin, Kwon, Min-Seok, Lee, Juyoung, Lee, Selyeong, Lin, Keng-Han, Maxwell, Taylor J, Nagai, Yoshihiko, Wang, Xu, Welch, Ryan P, Yoon, Joon, Zhang, Weihua, Barzilai, Nir, Voight, Benjamin F, Han, Bok-Ghee, Jenkinson, Christopher P, Kuulasmaa, Teemu, Kuusisto, Johanna, Manning, Alisa, Ng, Maggie C Y, Palmer, Nicholette D, Balkau, Beverley, Stančáková, Alena, Abboud, Hanna E, Boeing, Heiner, Giedraitis, Vilmantas, Prabhakaran, Dorairaj, Gottesman, Omri, Scott, James, Carey, Jason, Kwan, Phoenix, Grant, George, Smith, Joshua D, Neale, Benjamin M, Purcell, Shaun, Butterworth, Adam S, Howson, Joanna M M, Lee, Heung Man, Lu, Yingchang, Kwak, Soo-Heon, Zhao, Wei, Danesh, John, Lam, Vincent K L, Park, Kyong Soo, Saleheen, Danish, So, Wing Yee, Tam, Claudia H T, Afzal, Uzma, Aguilar, David, Arya, Rector, Aung, Tin, Chan, Edmund, Navarro, Carmen, Cheng, Ching-Yu, Palli, Domenico, Correa, Adolfo, Curran, Joanne E, Rybin, Denis, Farook, Vidya S, Fowler, Sharon P, Freedman, Barry I, Griswold, Michael, Hale, Daniel Esten, Hicks, Pamela J, Khor, Chiea-Chuen, Kumar, Satish, Lehne, Benjamin, Thuillier, Dorothée, Lim, Wei Yen, Liu, Jianjun, van der Schouw, Yvonne T, Loh, Marie, Musani, Solomon K, Puppala, Sobha, Scott, William R, Yengo, Loïc, Tan, Sian-Tsung, Taylor, Herman A, Thameem, Farook, Wilson, Gregory, Wong, Tien Yin, Njølstad, Pål Rasmus, Levy, Jonathan C, Mangino, Massimo, Bonnycastle, Lori L, Schwarzmayr, Thomas, Fadista, João, Surdulescu, Gabriela L, Herder, Christian, Groves, Christopher J, Wieland, Thomas, Bork-Jensen, Jette, Brandslund, Ivan, Christensen, Cramer, Koistinen, Heikki A, Doney, Alex S F, Kinnunen, Leena, Esko, Tõnu, Farmer, Andrew J, Hakaste, Liisa, Hodgkiss, Dylan, Kravic, Jasmina, Lyssenko, Valeriya, Hollensted, Mette, Jørgensen, Marit E, Jørgensen, Torben, Ladenvall, Claes, Justesen, Johanne Marie, Käräjämäki, Annemari, Kriebel, Jennifer, Rathmann, Wolfgang, Lannfelt, Lars, Lauritzen, Torsten, Narisu, Narisu, Linneberg, Allan, Melander, Olle, Milani, Lili, Neville, Matt, Orho-Melander, Marju, Qi, Lu, Qi, Qibin, Roden, Michael, Rolandsson, Olov, Swift, Amy, Rosengren, Anders H, Stirrups, Kathleen, Wood, Andrew R, Mihailov, Evelin, Blancher, Christine, Carneiro, Mauricio O, Maguire, Jared, Poplin, Ryan, Shakir, Khalid, Fennell, Timothy, DePristo, Mark, de Angelis, Martin Hrabé, Deloukas, Panos, Gjesing, Anette P, Jun, Goo, Nilsson, Peter, Murphy, Jacquelyn, Onofrio, Robert, Thorand, Barbara, Hansen, Torben, Meisinger, Christa, Hu, Frank B, Isomaa, Bo, Karpe, Fredrik, Liang, Liming, Peters, Annette, Huth, Cornelia, O'Rahilly, Stephen P, Palmer, Colin N A, Pedersen, Oluf, Rauramaa, Rainer, Tuomilehto, Jaakko, Salomaa, Veikko, Watanabe, Richard M, Syvänen, Ann-Christine, Bergman, Richard N, Bharadwaj, Dwaipayan, Bottinger, Erwin P, Cho, Yoon Shin, Chandak, Giriraj R, Chan, Juliana C N, Chia, Kee Seng, Daly, Mark J, Ebrahim, Shah B, Langenberg, Claudia, Elliott, Paul, Jablonski, Kathleen A, Lehman, Donna M, Jia, Weiping, Ma, Ronald C W, Pollin, Toni I, Sandhu, Manjinder, Tandon, Nikhil, Froguel, Philippe, Barroso, Inês, Teo, Yik Ying, Zeggini, Eleftheria, Loos, Ruth J F, Small, Kerrin S, Ried, Janina S, DeFronzo, Ralph A, Grallert, Harald, Glaser, Benjamin, Metspalu, Andres, Wareham, Nicholas J, Walker, Mark, Banks, Eric, Gieger, Christian, Ingelsson, Erik, Im, Hae Kyung, Illig, Thomas, Franks, Paul W, Buck, Gemma, Trakalo, Joseph, Buck, David, Prokopenko, Inga, Mägi, Reedik, Lind, Lars, Farjoun, Yossi, Owen, Katharine R, Gloyn, Anna L, Strauch, Konstantin, Tuomi, Tiinamaija, Kooner, Jaspal Singh, Lee, Jong-Young, Park, Taesung, Donnelly, Peter, Morris, Andrew D, Hattersley, Andrew T, Bowden, Donald W, Collins, Francis S, Atzmon, Gil, Chambers, John C, Spector, Timothy D, Laakso, Markku, Strom, Tim M, Bell, Graeme I, Blangero, John, Duggirala, Ravindranath, Tai, E Shyong, McVean, Gilean, Hanis, Craig L, Wilson, James G, Seielstad, Mark, Frayling, Timothy M, Meigs, James B, Cox, Nancy J, Sladek, Rob, Lander, Eric S, Gabriel, Stacey, Burtt, Noël P, Mohlke, Karen L, Meitinger, Thomas, Groop, Leif, Abecasis, Goncalo, Florez, Jose C, Scott, Laura J, Morris, Andrew P, Kang, Hyun Min, Boehnke, Michael, Altshuler, David, McCarthy, Mark I
Publicado 2016