Direct Effects of PPARα Agonists on Retinal Inflammation and Angiogenesis May Explain How Fenofibrate Lowers Risk of Severe Proliferative Diabetic Retinopathy

por Abcouwer, Steven F.
Publicado 2013

Müller Cell–Microglia Cross Talk Drives Neuroinflammation in Diabetic Retinopathy

por Abcouwer, Steven F.
Publicado 2017

Developmental and light regulation of tumor suppressor protein PP2A in the retina

por Rajala, Ammaji, Wang, Yuhong, Abcouwer, Steven F., Gardner, Thomas W., Rajala, Raju V.S.
Publicado 2017

TNF-α Signals Through PKCζ/NF-κB to Alter the Tight Junction Complex and Increase Retinal Endothelial Cell Permeability

por Aveleira, Célia A., Lin, Cheng-Mao, Abcouwer, Steven F., Ambrósio, António F., Antonetti, David A.
Publicado 2010

Minocycline prevents retinal inflammation and vascular permeability following ischemia-reperfusion injury

por Abcouwer, Steven F, Lin, Cheng-mao, Shanmugam, Sumathi, Muthusamy, Arivalagan, Barber, Alistair J, Antonetti, David A
Publicado 2013

Loss of High-Mobility Group Box 1 (HMGB1) Protein in Rods Accelerates Rod Photoreceptor Degeneration After Retinal Detachment

por Ross, Bing X., Choi, Joanne, Yao, Jingyu, Hager, Heather M., Abcouwer, Steven F., Zacks, David N.
Publicado 2020

All-trans-Retinaldehyde Contributes to Retinal Vascular Permeability in Ischemia Reperfusion

por Dreffs, Alyssa, Lin, Cheng-Mao, Liu, Xuwen, Shanmugam, Sumathi, Abcouwer, Steven F., Kern, Timothy S., Antonetti, David A.
Publicado 2020

Conditional Knock out of High-Mobility Group Box 1 (HMGB1) in Rods Reduces Autophagy Activation after Retinal Detachment

por Ross, Bing X., Jia, Lin, Kong, Dejuan, Wang, Tiantian, Hager, Heather M., Abcouwer, Steven F., Zacks, David N.
Publicado 2021

mTORC1-Independent Reduction of Retinal Protein Synthesis in Type 1 Diabetes

por Fort, Patrice E., Losiewicz, Mandy K., Pennathur, Subramaniam, Jefferson, Leonard S., Kimball, Scot R., Abcouwer, Steven F., Gardner, Thomas W.
Publicado 2014

Inflammatory resolution and vascular barrier restoration after retinal ischemia reperfusion injury

por Abcouwer, Steven F., Shanmugam, Sumathi, Muthusamy, Arivalagan, Lin, Cheng-mao, Kong, Dejuan, Hager, Heather, Liu, Xuwen, Antonetti, David A.
Publicado 2021

Hypoxia-Inducible Factor-1α in Rods Is Neuroprotective Following Retinal Detachment

por Ross, Bing X., Jia, Lin, Kong, Dejuan, Wang, Tiantian, Yao, Jingyu, Hager, Heather M., Abcouwer, Steven F., Zacks, David N.
Publicado 2022

Protective Effect of a GLP-1 Analog on Ischemia-Reperfusion Induced Blood–Retinal Barrier Breakdown and Inflammation

por Gonçalves, Andreia, Lin, Cheng-Mao, Muthusamy, Arivalagan, Fontes-Ribeiro, Carlos, Ambrósio, António F., Abcouwer, Steven F., Fernandes, Rosa, Antonetti, David A.
Publicado 2016

Delineating effects of angiopoietin-2 inhibition on vascular permeability and inflammation in models of retinal neovascularization and ischemia/reperfusion

por Canonica, Jérémie, Foxton, Richard, Garrido, Marina Garcia, Lin, Cheng-Mao, Uhles, Sabine, Shanmugam, Sumathi, Antonetti, David A., Abcouwer, Steven F., Westenskow, Peter D.
Publicado 2023

Vitreous Cytokine Expression and a Murine Model Suggest a Key Role of Microglia in the Inflammatory Response to Retinal Detachment

por Kiang, Lee, Ross, Bing X., Yao, Jingyu, Shanmugam, Sumathi, Andrews, Chris A., Hansen, Sean, Besirli, Cagri G., Zacks, David N., Abcouwer, Steven F.
Publicado 2018

Differential Roles of Hyperglycemia and Hypoinsulinemia in Diabetes Induced Retinal Cell Death: Evidence for Retinal Insulin Resistance

por Fort, Patrice E., Losiewicz, Mandy K., Reiter, Chad E. N., Singh, Ravi S. J., Nakamura, Makoto, Abcouwer, Steven F., Barber, Alistair J., Gardner, Thomas W.
Publicado 2011

Differential effects of minocycline on microvascular complications in murine models of type 1 and type 2 diabetes

por Eid, Stephanie A., O’Brien, Phillipe D., Hinder, Lucy M., Hayes, John M., Mendelson, Faye E., Zhang, Hongyu, Narayanan, Samanthi, Abcouwer, Steven F., Brosius, Frank C., Pennathur, Subramaniam, Savelieff, Masha G., Feldman, Eva L.
Publicado 2020

mTORC1 regulates high levels of protein synthesis in retinal ganglion cells of adult mice

por Fort, Patrice E., Losiewicz, Mandy K., Elghazi, Lynda, Kong, Dejuan, Cras-Méneur, Corentin, Fingar, Diane C., Kimball, Scot R., Rajala, Raju V.S., Smith, Alexander J., Ali, Robin R., Abcouwer, Steven F., Gardner, Thomas W.
Publicado 2022

Diminished retinal complex lipid synthesis and impaired fatty acid β-oxidation associated with human diabetic retinopathy

por Fort, Patrice E., Rajendiran, Thekkelnaycke M., Soni, Tanu, Byun, Jaeman, Shan, Yang, Looker, Helen C., Nelson, Robert G., Kretzler, Matthias, Michailidis, George, Roger, Jerome E., Gardner, Thomas W., Abcouwer, Steven F., Pennathur, Subramaniam, Afshinnia, Farsad
Publicado 2021

Mitochondrial uncoupling has no effect on microvascular complications in type 2 diabetes

por Hinder, Lucy M., Sas, Kelli M., O’Brien, Phillipe D., Backus, Carey, Kayampilly, Pradeep, Hayes, John M., Lin, Cheng-mao, Zhang, Hongyu, Shanmugam, Sumathi, Rumora, Amy E., Abcouwer, Steven F., Brosius, Frank C., Pennathur, Subramaniam, Feldman, Eva L.
Publicado 2019

Differential Effects of Empagliflozin on Microvascular Complications in Murine Models of Type 1 and Type 2 Diabetes

por Eid, Stephanie A., O’Brien, Phillipe D., Hinder, Lucy M., Hayes, John M., Mendelson, Faye E., Zhang, Hongyu, Zeng, Lixia, Kretzler, Katharina, Narayanan, Samanthi, Abcouwer, Steven F., Brosius, Frank C., Pennathur, Subramaniam, Savelieff, Masha G., Feldman, Eva L.
Publicado 2020