Recent progress and challenges in drug development against COVID-19 coronavirus (SARS-CoV-2) - an update on the status

por Abd El-Aziz, Tarek Mohamed, Stockand, James D.
Publicado 2020

Snake Venoms in Drug Discovery: Valuable Therapeutic Tools for Life Saving

por Mohamed Abd El-Aziz, Tarek, Soares, Antonio Garcia, Stockand, James D.
Publicado 2019

Human recombinant soluble ACE2 (hrsACE2) shows promise for treating severe COVID­19

por Abd El-Aziz, Tarek Mohamed, Al-Sabi, Ahmed, Stockand, James D.
Publicado 2020

Optogenetic Control of PIP2 Interactions Shaping ENaC Activity

por Abd El-Aziz, Tarek Mohamed, Kaur, Amanpreet, Shapiro, Mark S., Stockand, James D., Archer, Crystal R.
Publicado 2022

Editorial: Ion channels in health and disease

por Al-Sabi, Ahmed, Abd El-Aziz, Tarek Mohamed, Yu, Peilin, Rowe, Ashlee H., Wulff, Heike
Publicado 2022

Marine Brominated Tyrosine Alkaloids as Promising Inhibitors of SARS-CoV-2

por El-Demerdash, Amr, Hassan, Afnan, Abd El-Aziz, Tarek Mohamed, Stockand, James D., Arafa, Reem K.
Publicado 2021

P2Y(2) receptor decreases blood pressure by inhibiting ENaC

por Soares, Antonio G., Contreras, Jorge, Mironova, Elena, Archer, Crystal R., Stockand, James D., Abd El-Aziz, Tarek Mohamed
Publicado 2023

Cisplatin Decreases ENaC Activity Contributing to Renal Salt Wasting Syndrome

por Soares, Antonio G., Mironova, Elena, Archer, Crystal R., Contreras, Jorge, Stockand, James D., Abd El-Aziz, Tarek Mohamed
Publicado 2020

Chlorotoxin: A Helpful Natural Scorpion Peptide to Diagnose Glioma and Fight Tumor Invasion

por Dardevet, Lucie, Rani, Dipti, Abd El Aziz, Tarek, Bazin, Ingrid, Sabatier, Jean-Marc, Fadl, Mahmoud, Brambilla, Elisabeth, De Waard, Michel
Publicado 2015

Stimulation of the Epithelial Na(+) Channel in Renal Principal Cells by Gs-Coupled Designer Receptors Exclusively Activated by Designer Drugs

por Soares, Antonio G., Contreras, Jorge, Archer, Crystal R., Mironova, Elena, Berdeaux, Rebecca, Stockand, James D., Abd El-Aziz, Tarek Mohamed
Publicado 2021

The Search for Natural and Synthetic Inhibitors That Would Complement Antivenoms as Therapeutics for Snakebite Envenoming

por Gutiérrez, José María, Albulescu, Laura-Oana, Clare, Rachel H., Casewell, Nicholas R., Abd El-Aziz, Tarek Mohamed, Escalante, Teresa, Rucavado, Alexandra
Publicado 2021

Investigating the structure-activity relationship of marine polycyclic batzelladine alkaloids as promising inhibitors for SARS-CoV-2 main protease (M(pro))

por Elgohary, Alaa M., Elfiky, Abdo A., Pereira, Florbela, Abd El-Aziz, Tarek Mohamed, Sobeh, Mansour, Arafa, Reem K., El-Demerdash, Amr
Publicado 2022

Potential Role of Platelet-Activating C-Type Lectin-Like Proteins in Viper Envenomation Induced Thrombotic Microangiopathy Symptom

por Long, Chengbo, Liu, Ming, Tian, Huiwen, Li, Ya, Wu, Feilong, Mwangi, James, Lu, Qiumin, Mohamed Abd El-Aziz, Tarek, Lai, Ren, Shen, Chuanbin
Publicado 2020

Mechanisms and consequences of casein kinase II and ankyrin-3 regulation of the epithelial Na(+) channel

por Abd El-Aziz, Tarek Mohamed, Soares, Antonio G., Mironova, Elena, Boiko, Nina, Kaur, Amanpreet, Archer, Crystal R., Stockand, James D., Berman, Jonathan M.
Publicado 2021

Comprehensive Virtual Screening of the Antiviral Potentialities of Marine Polycyclic Guanidine Alkaloids against SARS-CoV-2 (COVID-19)

por El-Demerdash, Amr, Metwaly, Ahmed M., Hassan, Afnan, Abd El-Aziz, Tarek Mohamed, Elkaeed, Eslam B., Eissa, Ibrahim H., Arafa, Reem K., Stockand, James D.
Publicado 2021

Actiflagelin, a new sperm activator isolated from Walterinnesia aegyptia venom using phenotypic screening

por Abd El-Aziz, Tarek Mohamed, Al Khoury, Sawsan, Jaquillard, Lucie, Triquigneaux, Mathilde, Martinez, Guillaume, Bourgoin-Voillard, Sandrine, Sève, Michel, Arnoult, Christophe, Beroud, Rémy, De Waard, Michel
Publicado 2018

Deficiency of ROS-Activated TRPM2 Channel Protects Neurons from Cerebral Ischemia-Reperfusion Injury through Upregulating Autophagy

por Hu, Xupang, Wu, Lijuan, Liu, Xingyu, Zhang, Yi, Xu, Min, Fang, Qiuyuan, Lu, Lin, Niu, Jianguo, Abd El-Aziz, Tarek Mohamed, Jiang, Lin-Hua, Li, Fangfang, Yang, Wei
Publicado 2021

Identification and Characterization of Novel Proteins from Arizona Bark Scorpion Venom That Inhibit Nav1.8, a Voltage-Gated Sodium Channel Regulator of Pain Signaling

por Abd El-Aziz, Tarek Mohamed, Xiao, Yucheng, Kline, Jake, Gridley, Harold, Heaston, Alyse, Linse, Klaus D., Ward, Micaiah J., Rokyta, Darin R., Stockand, James D., Cummins, Theodore R., Fornelli, Luca, Rowe, Ashlee H.
Publicado 2021

Structural and Functional Characterization of a Novel Scorpion Toxin that Inhibits Na(V)1.8 via Interactions With the DI Voltage Sensor and DII Pore Module

por George, Kiran, Lopez-Mateos, Diego, Abd El-Aziz, Tarek Mohamed, Xiao, Yucheng, Kline, Jake, Bao, Hong, Raza, Syed, Stockand, James D., Cummins, Theodore R., Fornelli, Luca, Rowe, Matthew P., Yarov-Yarovoy, Vladimir, Rowe, Ashlee H.
Publicado 2022

Identification, Characterization and Synthesis of Walterospermin, a Sperm Motility Activator from the Egyptian Black Snake Walterinnesia aegyptia Venom

por Abd El-Aziz, Tarek Mohamed, Jaquillard, Lucie, Bourgoin-Voillard, Sandrine, Martinez, Guillaume, Triquigneaux, Mathilde, Zoukimian, Claude, Combemale, Stéphanie, Hograindleur, Jean-Pascal, Al Khoury, Sawsan, Escoffier, Jessica, Michelland, Sylvie, Bulet, Philippe, Beroud, Rémy, Seve, Michel, Arnoult, Christophe, De Waard, Michel
Publicado 2020