Icotinib, Almonertinib, and Olmutinib: A 2D Similarity/Docking-Based Study to Predict the Potential Binding Modes and Interactions into EGFR

por Almalki, Faisal A., Shawky, Ahmed M., Abdalla, Ashraf N., Gouda, Ahmed M.
Publicado 2021

Pharmacophore-based virtual screening, synthesis, biological evaluation, and molecular docking study of novel pyrrolizines bearing urea/thiourea moieties with potential cytotoxicit...

por Shawky, Ahmed M., Ibrahim, Nashwa A., Abourehab, Mohammed A. S., Abdalla, Ashraf N., Gouda, Ahmed M.
Publicado 2020

Chemosensitization of HT29 and HT29-5FU Cell Lines by a Combination of a Multi-Tyrosine Kinase Inhibitor and 5FU Downregulates ABCC1 and Inhibits PIK3CA in Light of Their Importanc...

por Abdalla, Ashraf N., Malki, Waleed H., Qattan, Amal, Shahid, Imran, Hossain, Mohammad Akbar, Ahmed, Muhammad
Publicado 2021

Novel pyrrolizines bearing 3,4,5-trimethoxyphenyl moiety: design, synthesis, molecular docking, and biological evaluation as potential multi-target cytotoxic agents

por Shawky, Ahmed M., Ibrahim, Nashwa A., Abdalla, Ashraf N., Abourehab, Mohammed A. S., Gouda, Ahmed M.
Publicado 2021

A Comprehensive Overview of Globally Approved JAK Inhibitors

por Shawky, Ahmed M., Almalki, Faisal A., Abdalla, Ashraf N., Abdelazeem, Ahmed H., Gouda, Ahmed M.
Publicado 2022

Consensus small interfering RNA targeted to stem-loops II and III of IRES structure of 5′ UTR effectively inhibits virus replication and translation of HCV sub-genotype 4a isolates...

por AlMalki, Waleed H., Shahid, Imran, Abdalla, Ashraf N., Johargy, Ayman K., Ahmed, Muhammad, Hassan, Sajida
Publicado 2021

Virological surveillance, molecular phylogeny, and evolutionary dynamics of hepatitis C virus subtypes 1a and 4a isolates in patients from Saudi Arabia

por AlMalki, Waleed H., Shahid, Imran, Abdalla, Ashraf N., Johargy, Ayman K., Ahmed, Muhammad, Hassan, Sajida
Publicado 2021

In Silico Approach Using Free Software to Optimize the Antiproliferative Activity and Predict the Potential Mechanism of Action of Pyrrolizine-Based Schiff Bases

por Almalki, Faisal A., Abdalla, Ashraf N., Shawky, Ahmed M., El Hassab, Mahmoud A., Gouda, Ahmed M.
Publicado 2021

Quinazolin-4(3H)-one based potential multiple tyrosine kinase inhibitors with excellent cytotoxicity

por Mirgany, Tebyan O., Abdalla, Ashraf N., Arifuzzaman, Md, Motiur Rahman, A. F. M., Al-Salem, Huda S.
Publicado 2021

A Novel Approach to Develop New and Potent Inhibitors for the Simultaneous Inhibition of Protease and Helicase Activities of HCV NS3/4A Protease: A Computational Approach

por Riaz, Muhammad, Rehman, Ashfaq Ur, Waqas, Muhammad, Khalid, Asaad, Abdalla, Ashraf N., Mahmood, Arif, Hu, Junjian, Wadood, Abdul
Publicado 2023

Para-Substituted Thiosemicarbazones as Cholinesterase Inhibitors: Synthesis, In Vitro Biological Evaluation, and In Silico Study

por Khan, Momin, Gohar, Hina, Alam, Aftab, Wadood, Abdul, Shareef, Azam, Ali, Mahboob, Khalid, Asaad, Abdalla, Ashraf N., Ullah, Farhat
Publicado 2023

The vital role of animal, marine, and microbial natural products against COVID-19

por Alqathama, Aljawharah A., Ahmad, Rizwan, Alsaedi, Ruba B., Alghamdi, Raghad A., Abkar, Ekram H., Alrehaly, Rola H., Abdalla, Ashraf N.
Publicado 2022

Proapoptotic Activity of Achillea membranacea Essential Oil and Its Major Constituent 1,8-Cineole against A2780 Ovarian Cancer Cells

por Abdalla, Ashraf N., Shaheen, Usama, Abdallah, Qasem M. A., Flamini, Guido, Bkhaitan, Majdi M., Abdelhady, Mohamed I. S., Ascrizzi, Roberta, Bader, Ammar
Publicado 2020

Isolation, Characterization, Complete Structural Assignment, and Anticancer Activities of the Methoxylated Flavonoids from Rhamnus disperma Roots

por Mohammed, Hamdoon A., Abd El-Wahab, Mohammed F., Shaheen, Usama, Mohammed, Abd El-Salam I., Abdalla, Ashraf N., Ragab, Ehab A.
Publicado 2021

Olive Leaf Extracts for a Green Synthesis of Silver-Functionalized Multi-Walled Carbon Nanotubes

por Alhajri, Hassna Mohammed, Aloqaili, Sadeem Salih, Alterary, Seham S., Alqathama, Aljawharah, Abdalla, Ashraf N., Alzhrani, Rami M., Alotaibi, Bander S., Alsaab, Hashem O.
Publicado 2022

Multi-Fold Computational Analysis to Discover Novel Putative Inhibitors of Isethionate Sulfite-Lyase (Isla) from Bilophila wadsworthia: Combating Colorectal Cancer and Inflammatory...

por Waqas, Muhammad, Halim, Sobia Ahsan, Ullah, Atta, Ali, Assim Alaa Mohammed, Khalid, Asaad, Abdalla, Ashraf N., Khan, Ajmal, Al-Harrasi, Ahmed
Publicado 2023

Comparative Expression Analysis of Breakpoint Cluster Region–Abelson Oncogene in Leukemia Patients

por Arshad, Farah, Ali, Amjad, Rehman, Gauhar, Halim, Sobia Ahsan, Waqas, Muhammad, Khalid, Asaad, Abdalla, Ashraf N., Khan, Ajmal, Al-Harrasi, Ahmed
Publicado 2023

A Series of Isatin-Hydrazones with Cytotoxic Activity and CDK2 Kinase Inhibitory Activity: A Potential Type II ATP Competitive Inhibitor

por Al-Salem, Huda S., Arifuzzaman, Md, Alkahtani, Hamad M., Abdalla, Ashraf N., Issa, Iman S., Alqathama, Aljawharah, Albalawi, Fatemah S., Rahman, A. F. M. Motiur
Publicado 2020

Pyrrolizine/Indolizine-NSAID Hybrids: Design, Synthesis, Biological Evaluation, and Molecular Docking Studies

por Abourehab, Mohammed A. S., Alqahtani, Alaa M., Almalki, Faisal A., Zaher, Dana M., Abdalla, Ashraf N., Gouda, Ahmed M., Beshr, Eman A. M.
Publicado 2021

Antiamnesic Effects of Novel Phthalimide Derivatives in Scopolamine-Induced Memory Impairment in Mice: A Useful Therapy for Alzheimer’s Disease

por Karim, Nasiara, Khan, Inbisat, Khan, Imran, Halim, Sobia Ahsan, Khalid, Asaad, Abdalla, Ashraf N., Rehman, Najeeb Ur, Khan, Ajmal, Al-Harrasi, Ahmed
Publicado 2023