Mutations in Epigenetic Modifiers in Myeloid Malignancies and the Prospect of Novel Epigenetic-Targeted Therapy

por Fathi, Amir T., Abdel-Wahab, Omar
Publicado 2012

Partial loss of genes might open therapeutic window

por Liu, Bo, Abdel-Wahab, Omar
Publicado 2017

Metabolism and the leukemic stem cell

por Abdel-Wahab, Omar, Levine, Ross L.
Publicado 2010

Recent advances in the treatment of acute myeloid leukemia

por Abdel-Wahab, Omar, Levine, Ross L
Publicado 2010

BRAF-mutant hematopoietic malignancies

por Abdel-Wahab, Omar, Park, Christopher Y.
Publicado 2014

Translating recent advances in the pathogenesis of acute myeloid leukemia to the clinic

por Bewersdorf, Jan Philipp, Abdel-Wahab, Omar
Publicado 2022

Spliceosomal gene mutations in myelodysplasia: molecular links to clonal abnormalities of hematopoiesis

por Inoue, Daichi, Bradley, Robert K., Abdel-Wahab, Omar
Publicado 2016

Overlaid Transcriptional and Proteome Analyses Identify Mitotic Kinesins as Important Targets of Arylsulfonamide-Mediated RBM39 Degradation

por Coomar, Seemon, Mota, Pedro, Penson, Alexander, Schwaller, Jürg, Abdel-Wahab, Omar, Gillingham, Dennis
Publicado 2023

Widespread intronic polyadenylation inactivates tumor suppressor genes in leukemia

por Lee, Shih-Han, Singh, Irtisha, Tisdale, Sarah, Abdel-Wahab, Omar, Leslie, Christina S., Mayr, Christine
Publicado 2018

Recurrent SRSF2 mutations in MDS affect both splicing and NMD

por Rahman, Mohammad Alinoor, Lin, Kuan-Ting, Bradley, Robert K., Abdel-Wahab, Omar, Krainer, Adrian R.
Publicado 2020

Diffuse reduction of cerebral grey matter volumes in Erdheim-Chester disease

por Diamond, Eli L., Hatzoglou, Vaios, Patel, Sneha, Abdel-Wahab, Omar, Rampal, Raajit, Hyman, David M., Holodny, Andrei I., Raj, Ashish
Publicado 2016

Histiocytosis and the nervous system: from diagnosis to targeted therapies

por Cohen Aubart, Fleur, Idbaih, Ahmed, Emile, Jean-François, Amoura, Zahir, Abdel-Wahab, Omar, Durham, Benjamin H, Haroche, Julien, Diamond, Eli L
Publicado 2021

Quantification of tumor-derived cell free DNA(cfDNA) by digital PCR (DigPCR) in cerebrospinal fluid of patients with BRAF(V600) mutated malignancies

por Momtaz, Parisa, Pentsova, Elena, Abdel-Wahab, Omar, Diamond, Eli, Hyman, David, Merghoub, Taha, You, Daoqi, Gasmi, Billel, Viale, Agnes, Chapman, Paul B.
Publicado 2016

Splicing factor SF3B1(K700E) mutant dysregulates erythroid differentiation via aberrant alternative splicing of transcription factor TAL1

por Jin, Shuiling, Su, Hairui, Tran, Ngoc-Tung, Song, Jing, Lu, Sydney S., Li, Ying, Huang, Suming, Abdel-Wahab, Omar, Liu, Yanyan, Zhao, Xinyang
Publicado 2017

Dual BRAF/MEK blockade restores CNS responses in BRAF-mutant Erdheim–Chester disease patients following BRAF inhibitor monotherapy

por Mazor, Roei D, Weissman, Ran, Luckman, Judith, Domachevsky, Liran, Diamond, Eli L, Abdel-Wahab, Omar, Shapira, Shirley, Hershkovitz-Rokah, Oshrat, Groshar, David, Shpilberg, Ofer
Publicado 2020

Impaired hematopoiesis and leukemia development in mice with a conditional knock-in allele of a mutant splicing factor gene U2af1

por Fei, Dennis Liang, Zhen, Tao, Durham, Benjamin, Ferrarone, John, Zhang, Tuo, Garrett, Lisa, Yoshimi, Akihide, Abdel-Wahab, Omar, Bradley, Robert K., Liu, Paul, Varmus, Harold
Publicado 2018

The JAK2V617F oncogene requires expression of inducible phosphofructokinase/fructose-bisphosphatase 3 for cell growth and increased metabolic activity

por Reddy, Mamatha M., Fernandes, Margret S., Deshpande, Anagha, Weisberg, Ellen, Inguilizian, Haig V., Abdel-Wahab, Omar, Kung, Andrew L., Levine, Ross L., Griffin, James D., Sattler, Martin
Publicado 2011

ASXL1 plays an important role in erythropoiesis

por Shi, Hui, Yamamoto, Shohei, Sheng, Mengyao, Bai, Jie, Zhang, Peng, Chen, Runze, Chen, Shi, Shi, Lihong, Abdel-Wahab, Omar, Xu, Mingjiang, Zhou, Yuan, Yang, Feng-Chun
Publicado 2016

CSF1R inhibition for histiocytic neoplasm with CBL mutations refractory to MEK1/2 inhibition

por Diamond, Eli L., Francis, Jasmine H., Lacouture, Mario E., Rotemberg, Veronica, Yabe, Mariko, Petrova-Drus, Kseniya, Ulaner, Gary A., Reddy, Ryan, Abdel-Wahab, Omar, Durham, Benjamin H.
Publicado 2023

HDL and Glut1 inhibition reverse a hypermetabolic state in mouse models of myeloproliferative disorders

por Gautier, Emmanuel L., Westerterp, Marit, Bhagwat, Neha, Cremers, Serge, Shih, Alan, Abdel-Wahab, Omar, Lütjohann, Dieter, Randolph, Gwendalyn J., Levine, Ross L., Tall, Alan R., Yvan-Charvet, Laurent
Publicado 2013