Identification of BACE2 as an avid ß-amyloid-degrading protease

por Abdul-Hay, Samer O, Sahara, Tomoko, McBride, Melinda, Kang, Dongcheul, Leissring, Malcolm A
Publicado 2012

Deletion of Insulin-Degrading Enzyme Elicits Antipodal, Age-Dependent Effects on Glucose and Insulin Tolerance

por Abdul-Hay, Samer O., Kang, Dongcheul, McBride, Melinda, Li, Lilin, Zhao, Ji, Leissring, Malcolm A.
Publicado 2011

Cathepsin D regulates cerebral Aβ42/40 ratios via differential degradation of Aβ42 and Aβ40

por Suire, Caitlin N., Abdul-Hay, Samer O., Sahara, Tomoko, Kang, Dongcheul, Brizuela, Monica K., Saftig, Paul, Dickson, Dennis W., Rosenberry, Terrone L., Leissring, Malcolm A.
Publicado 2020

Prominent tauopathy and intracellular β-amyloid accumulation triggered by genetic deletion of cathepsin D: Implications for Alzheimer disease pathogenesis

por Terron, Heather M., Parikh, Sagar J., Abdul-Hay, Samer O., Sahara, Tomoko, Kang, Dongcheul, Dickson, Dennis W., Saftig, Paul, LaFerla, Frank M., Lane, Shelley, Leissring, Malcolm A.
Publicado 2023

Designed Inhibitors of Insulin-Degrading Enzyme Regulate the Catabolism and Activity of Insulin

por Leissring, Malcolm A., Malito, Enrico, Hedouin, Sabrine, Reinstatler, Lael, Sahara, Tomoko, Abdul-Hay, Samer O., Choudhry, Shakeel, Maharvi, Ghulam M., Fauq, Abdul H., Huzarska, Malwina, May, Philip S., Choi, Sungwoon, Logan, Todd P., Turk, Benjamin E., Cantley, Lewis C., Manolopoulou, Marika, Tang, Wei-Jen, Stein, Ross L., Cuny, Gregory D., Selkoe, Dennis J.
Publicado 2010

LRRTM3 Interacts with APP and BACE1 and Has Variants Associating with Late-Onset Alzheimer’s Disease (LOAD)

por Lincoln, Sarah, Allen, Mariet, Cox, Claire L., Walker, Louise P., Malphrus, Kimberly, Qiu, Yushi, Nguyen, Thuy, Rowley, Christopher, Kouri, Naomi, Crook, Julia, Pankratz, V. Shane, Younkin, Samuel, Younkin, Linda, Carrasquillo, Minerva, Zou, Fanggeng, Abdul-Hay, Samer O., Springer, Wolfdieter, Sando, Sigrid B., Aasly, Jan O., Barcikowska, Maria, Wszolek, Zbigniew K., Lewis, Jada M., Dickson, Dennis, Graff-Radford, Neill R., Petersen, Ronald C., Eckman, Elizabeth, Younkin, Steven G., Ertekin-Taner, Nilüfer
Publicado 2013