Application of a Physiologically Based Pharmacokinetic Approach to Predict Theophylline Pharmacokinetics Using Virtual Non-Pregnant, Pregnant, Fetal, Breast-Feeding, and Neonatal P...

por Abduljalil, Khaled, Gardner, Iain, Jamei, Masoud
Publicado 2022

Drug Dosing in Pregnant Women: Challenges and Opportunities in Using Physiologically Based Pharmacokinetic Modeling and Simulations

por Ke, Alice Ban, Greupink, Rick, Abduljalil, Khaled
Publicado 2018

Prediction of drug concentrations in milk during breastfeeding, integrating predictive algorithms within a physiologically‐based pharmacokinetic model

por Abduljalil, Khaled, Pansari, Amita, Ning, Jia, Jamei, Masoud
Publicado 2021

Quantification of Fetal Renal Function Using Fetal Urine Production Rate and Its Reflection on the Amniotic and Fetal Creatinine Levels During Pregnancy

por Ezuruike, Udoamaka, Blenkinsop, Alexander, Pansari, Amita, Abduljalil, Khaled
Publicado 2022

More Power to OATP1B1: An Evaluation of Sample Size in Pharmacogenetic Studies Using a Rosuvastatin PBPK Model for Intestinal, Hepatic, and Renal Transporter‐Mediated Clearances

por Emami Riedmaier, Ariane, Burt, Howard, Abduljalil, Khaled, Neuhoff, Sibylle
Publicado 2016

Does age affect gastric emptying time? A model‐based meta‐analysis of data from premature neonates through to adults

por Bonner, Jennifer J., Vajjah, Pavan, Abduljalil, Khaled, Jamei, Masoud, Rostami‐Hodjegan, Amin, Tucker, Geoffrey T., Johnson, Trevor N.
Publicado 2015

Applications of linking PBPK and PD models to predict the impact of genotypic variability, formulation differences, differences in target binding capacity and target site drug conc...

por Chetty, Manoranjenni, Rose, Rachel H., Abduljalil, Khaled, Patel, Nikunjkumar, Lu, Gaohua, Cain, Theresa, Jamei, Masoud, Rostami-Hodjegan, Amin
Publicado 2014

Assessment of Maternal and Fetal Dolutegravir Exposure by Integrating Ex Vivo Placental Perfusion Data and Physiologically‐Based Pharmacokinetic Modeling

por Freriksen, Jolien J.M., Schalkwijk, Stein, Colbers, Angela P., Abduljalil, Khaled, Russel, Frans G.M., Burger, David M., Greupink, Rick
Publicado 2020

Application of a Physiologically Based Pharmacokinetic Model to Predict Cefazolin and Cefuroxime Disposition in Obese Pregnant Women Undergoing Caesarean Section

por Alrammaal, Hanadi H., Abduljalil, Khaled, Hodgetts Morton, Victoria, Morris, R. Katie, Marriott, John F., Chong, Hsu P., Batchelor, Hannah K.
Publicado 2022

Population PBPK modeling using parametric and nonparametric methods of the Simcyp Simulator, and Bayesian samplers

por Wedagedera, Janak R., Afuape, Anthonia, Chirumamilla, Siri Kalyan, Momiji, Hiroshi, Leary, Robert, Dunlavey, Mike, Matthews, Richard, Abduljalil, Khaled, Jamei, Masoud, Bois, Frederic Y.
Publicado 2022