Estimating treatment prolongation for persistent infections

por Martinecz, Antal, Abel zur Wiesch, Pia
Publicado 2018

Mathematical Modeling of Remdesivir to Treat COVID-19: Can Dosing Be Optimized?

por Conway, Jessica M., Abel zur Wiesch, Pia
Publicado 2021

Using Chemical Reaction Kinetics to Predict Optimal Antibiotic Treatment Strategies

por Abel zur Wiesch, Pia, Clarelli, Fabrizio, Cohen, Ted
Publicado 2017

Selection or drift: The population biology underlying transposon insertion sequencing experiments

por Mahmutovic, Anel, Abel zur Wiesch, Pia, Abel, Sören
Publicado 2020

Informed Switching Strongly Decreases the Prevalence of Antibiotic Resistance in Hospital Wards

por Kouyos, Roger D., Abel zur Wiesch, Pia, Bonhoeffer, Sebastian
Publicado 2011

On Being the Right Size: The Impact of Population Size and Stochastic Effects on the Evolution of Drug Resistance in Hospitals and the Community

por Kouyos, Roger D., Abel zur Wiesch, Pia, Bonhoeffer, Sebastian
Publicado 2011

The Role of Adherence and Retreatment in De Novo Emergence of MDR-TB

por Cadosch, Dominique, Abel zur Wiesch, Pia, Kouyos, Roger, Bonhoeffer, Sebastian
Publicado 2016

Reaction Kinetic Models of Antibiotic Heteroresistance

por Martinecz, Antal, Clarelli, Fabrizio, Abel, Sören, Abel zur Wiesch, Pia
Publicado 2019

The Infectious Dose Shapes Vibrio cholerae Within-Host Dynamics

por Gillman, Aaron Nicholas, Mahmutovic, Anel, Abel zur Wiesch, Pia, Abel, Sören
Publicado 2021

Cycling Empirical Antibiotic Therapy in Hospitals: Meta-Analysis and Models

por Abel zur Wiesch, Pia, Kouyos, Roger, Abel, Sören, Viechtbauer, Wolfgang, Bonhoeffer, Sebastian
Publicado 2014

Analysis of Bottlenecks in Experimental Models of Infection

por Abel, Sören, Abel zur Wiesch, Pia, Davis, Brigid M., Waldor, Matthew K.
Publicado 2015

Multi-scale modeling of drug binding kinetics to predict drug efficacy

por Clarelli, Fabrizio, Liang, Jingyi, Martinecz, Antal, Heiland, Ines, Abel zur Wiesch, Pia
Publicado 2019

Bi-modal Distribution of the Second Messenger c-di-GMP Controls Cell Fate and Asymmetry during the Caulobacter Cell Cycle

por Abel, Sören, Bucher, Tabitha, Nicollier, Micaël, Hug, Isabelle, Kaever, Volkhard, Abel zur Wiesch, Pia, Jenal, Urs
Publicado 2013

Smear positivity in paediatric and adult tuberculosis: systematic review and meta-analysis

por Kunkel, Amber, Abel zur Wiesch, Pia, Nathavitharana, Ruvandhi R., Marx, Florian M., Jenkins, Helen E., Cohen, Ted
Publicado 2016

Drug-target binding quantitatively predicts optimal antibiotic dose levels in quinolones

por Clarelli, Fabrizio, Palmer, Adam, Singh, Bhupender, Storflor, Merete, Lauksund, Silje, Cohen, Ted, Abel, Sören, Abel zur Wiesch, Pia
Publicado 2020

High rifampicin peak plasma concentrations accelerate the slow phase of bacterial decline in tuberculosis patients: Evidence for heteroresistance

por Martinecz, Antal, Boeree, Martin J., Diacon, Andreas H., Dawson, Rodney, Hemez, Colin, Aarnoutse, Rob E., Abel zur Wiesch, Pia
Publicado 2023

Mechanisms of antibiotic action shape the fitness landscapes of resistance mutations

por Hemez, Colin, Clarelli, Fabrizio, Palmer, Adam C., Bleis, Christina, Abel, Sören, Chindelevitch, Leonid, Cohen, Theodore, Abel zur Wiesch, Pia
Publicado 2022

RESTAMP – Rate estimates by sequence-tag analysis of microbial populations

por Mahmutovic, Anel, Gillman, Aaron Nicholas, Lauksund, Silje, Robson Moe, Natasha-Anne, Manzi, Aime, Storflor, Merete, Abel zur Wiesch, Pia, Abel, Sören
Publicado 2021

vCOMBAT: a novel tool to create and visualize a computational model of bacterial antibiotic target-binding

por Tran, Vi Ngoc-Nha, Shams, Alireza, Ascioglu, Sinan, Martinecz, Antal, Liang, Jingyi, Clarelli, Fabrizio, Mostowy, Rafal, Cohen, Ted, Abel zur Wiesch, Pia
Publicado 2022

Transposon-insertion sequencing screens unveil requirements for EHEC growth and intestinal colonization

por Warr, Alyson R., Hubbard, Troy P., Munera, Diana, Blondel, Carlos J., Abel zur Wiesch, Pia, Abel, Sören, Wang, Xiaoxue, Davis, Brigid M., Waldor, Matthew K.
Publicado 2019