A Case Study of Clinical Response to Rucaparib in a Patient with Metastatic Castration-Resistant Prostate Cancer and a RAD51B Alteration

por Sautois, Brieuc, Loehr, Andrea, Watkins, Simon P., Schroeder, Hélène, Abida, Wassim
Publicado 2022

Guidelines for Management of Treatment-Emergent Adverse Events During Rucaparib Treatment of Patients with Metastatic Castration-Resistant Prostate Cancer

por Labadie, Brian W, Morris, David S, Bryce, Alan H, Given, Robert, Zhang, Jingsong, Abida, Wassim, Chowdhury, Simon, Patnaik, Akash
Publicado 2022

Phase I Study of Everolimus in Combination with Gemcitabine and Split-Dose Cisplatin in Advanced Urothelial Carcinoma

por Abida, Wassim, Milowsky, Matthew I., Ostrovnaya, Irina, Gerst, Scott R., Rosenberg, Jonathan E., Voss, Martin H., Apolo, Andrea B., Regazzi, Ashley M., McCoy, Asia S., Boyd, Mariel E., Bajorin, Dean F.
Publicado 2016

Tumor copy number alteration burden is a pan-cancer prognostic factor associated with recurrence and death

por Hieronymus, Haley, Murali, Rajmohan, Tin, Amy, Yadav, Kamlesh, Abida, Wassim, Moller, Henrik, Berney, Daniel, Scher, Howard, Carver, Brett, Scardino, Peter, Schultz, Nikolaus, Taylor, Barry, Vickers, Andrew, Cuzick, Jack, Sawyers, Charles L
Publicado 2018

Regulation of the glucocorticoid receptor via a BET-dependent enhancer drives antiandrogen resistance in prostate cancer

por Shah, Neel, Wang, Ping, Wongvipat, John, Karthaus, Wouter R, Abida, Wassim, Armenia, Joshua, Rockowitz, Shira, Drier, Yotam, Bernstein, Bradley E, Long, Henry W, Freedman, Matthew L, Arora, Vivek K, Zheng, Deyou, Sawyers, Charles L
Publicado 2017

AKT mutant allele-specific activation dictates pharmacologic sensitivities

por Shrestha Bhattarai, Tripti, Shamu, Tambudzai, Gorelick, Alexander N., Chang, Matthew T., Chakravarty, Debyani, Gavrila, Elena I., Donoghue, Mark T. A., Gao, JianJong, Patel, Swati, Gao, Sizhi Paul, Reynolds, Margaret H., Phillips, Sarah M., Soumerai, Tara, Abida, Wassim, Hyman, David M., Schram, Alison M., Solit, David B., Smyth, Lillian M., Taylor, Barry S.
Publicado 2022

Rucaparib in Men With Metastatic Castration-Resistant Prostate Cancer Harboring a BRCA1 or BRCA2 Gene Alteration

por Abida, Wassim, Patnaik, Akash, Campbell, David, Shapiro, Jeremy, Bryce, Alan H., McDermott, Ray, Sautois, Brieuc, Vogelzang, Nicholas J., Bambury, Richard M., Voog, Eric, Zhang, Jingsong, Piulats, Josep M., Ryan, Charles J., Merseburger, Axel S., Daugaard, Gedske, Heidenreich, Axel, Fizazi, Karim, Higano, Celestia S., Krieger, Laurence E., Sternberg, Cora N., Watkins, Simon P., Despain, Darrin, Simmons, Andrew D., Loehr, Andrea, Dowson, Melanie, Golsorkhi, Tony, Chowdhury, Simon
Publicado 2020

Tumor Microenvironment-Derived NRG1 Promotes Antiandrogen Resistance in Prostate Cancer

por Zhang, Zeda, Karthaus, Wouter R., Lee, Young Sun, Gao, Vianne R., Wu, Chao, Russo, Joshua W., Liu, Menghan, Mota, Jose Mauricio, Abida, Wassim, Linton, Eliot, Lee, Eugine, Barnes, Spencer D., Chen, Hsuan-An, Mao, Ninghui, Wongvipat, John, Choi, Danielle, Chen, Xiaoping, Zhao, Huiyong, Manova-Todorova, Katia, de Stanchina, Elisa, Taplin, Mary-Ellen, Balk, Steven P., Rathkopf, Dana E., Gopalan, Anuradha, Carver, Brett S., Mu, Ping, Jiang, Xuejun, Watson, Philip A., Sawyers, Charles L.
Publicado 2020

Loss of CHD1 Promotes Heterogeneous Mechanisms of Resistance to AR-Targeted Therapy via Chromatin Dysregulation

por Zhang, Zeda, Zhou, Chuanli, Li, Xiaoling, Barnes, Spencer D., Deng, Su, Hoover, Elizabeth, Chen, Chi-Chao, Lee, Young Sun, Zhang, Yanxiao, Wang, Choushi, Metang, Lauren A., Wu, Chao, Tirado, Carla Rodriguez, Johnson, Nickolas A., Wongvipat, John, Navrazhina, Kristina, Cao, Zhen, Choi, Danielle, Huang, Chun-Hao, Linton, Eliot, Chen, Xiaoping, Liang, Yupu, Mason, Christopher E., de Stanchina, Elisa, Abida, Wassim, Lujambio, Amaia, Li, Sheng, Lowe, Scott W., Mendell, Joshua T., Malladi, Venkat S., Sawyers, Charles L., Mu, Ping
Publicado 2020

Tumor fraction-guided cell-free DNA profiling in metastatic solid tumor patients

por Tsui, Dana W. Y., Cheng, Michael L., Shady, Maha, Yang, Julie L., Stephens, Dennis, Won, Helen, Srinivasan, Preethi, Huberman, Kety, Meng, Fanli, Jing, Xiaohong, Patel, Juber, Hasan, Maysun, Johnson, Ian, Gedvilaite, Erika, Houck-Loomis, Brian, Socci, Nicholas D., Selcuklu, S. Duygu, Seshan, Venkatraman E., Zhang, Hongxin, Chakravarty, Debyani, Zehir, Ahmet, Benayed, Ryma, Arcila, Maria, Ladanyi, Marc, Funt, Samuel A., Feldman, Darren R., Li, Bob T., Razavi, Pedram, Rosenberg, Jonathan, Bajorin, Dean, Iyer, Gopa, Abida, Wassim, Scher, Howard I., Rathkopf, Dana, Viale, Agnes, Berger, Michael F., Solit, David B.
Publicado 2021

BET Bromodomain Inhibition Blocks an AR-Repressed, E2F1-Activated Treatment-Emergent Neuroendocrine Prostate Cancer Lineage Plasticity Program

por Kim, Dae-Hwan, Sun, Duanchen, Storck, William K., Welker Leng, Katherine, Jenkins, Chelsea, Coleman, Daniel J., Sampson, David, Guan, Xiangnan, Kumaraswamy, Anbarasu, Rodansky, Eva S., Urrutia, Joshua A., Schwartzman, Jacob A., Zhang, Chao, Beltran, Himisha, Labrecque, Mark P., Morrissey, Colm, Lucas, Jared M., Coleman, Ilsa M., Nelson, Peter S., Corey, Eva, Handelman, Samuel K., Sexton, Jonathan Z., Aggarwal, Rahul, Abida, Wassim, Feng, Felix Y., Small, Eric J., Spratt, Daniel E., Bankhead, Armand, Rao, Arvind, Gesner, Emily M., Attwell, Sarah, Lakhotia, Sanjay, Campeau, Eric, Yates, Joel A., Xia, Zheng, Alumkal, Joshi J.
Publicado 2021

The long tail of oncogenic drivers in prostate cancer

por Armenia, Joshua, Wankowicz, Stephanie A.M., Liu, David, Gao, Jianjiong, Kundra, Ritika, Reznik, Ed, Chatila, Walid K., Chakravarty, Debyani, Han, G. Celine, Coleman, Ilsa, Montgomery, Bruce, Pritchard, Colin, Morrissey, Colm, Barbieri, Christopher E., Beltran, Himisha, Sboner, Andrea, Zafeiriou, Zafeiris, Miranda, Susana, Bielski, Craig M., Penson, Alexander V., Tolonen, Charlotte, Huang, Franklin W., Robinson, Dan, Wu, Yi Mi, Lonigro, Robert, Garraway, Levi A., Demichelis, Francesca, Kantoff, Philip W., Taplin, Mary-Ellen, Abida, Wassim, Taylor, Barry S., Scher, Howard I., Nelson, Peter S., de Bono, Johann S., Rubin, Mark A., Sawyers, Charles L., Chinnaiyan, Arul M., Schultz, Nikolaus, Van Allen, Eliezer M.
Publicado 2018

Genomic correlates of clinical outcome in advanced prostate cancer

por Abida, Wassim, Cyrta, Joanna, Heller, Glenn, Prandi, Davide, Armenia, Joshua, Coleman, Ilsa, Cieslik, Marcin, Benelli, Matteo, Robinson, Dan, Van Allen, Eliezer M., Sboner, Andrea, Fedrizzi, Tarcisio, Mosquera, Juan Miguel, Robinson, Brian D., De Sarkar, Navonil, Kunju, Lakshmi P., Tomlins, Scott, Wu, Yi Mi, Nava Rodrigues, Daniel, Loda, Massimo, Gopalan, Anuradha, Reuter, Victor E., Pritchard, Colin C., Mateo, Joaquin, Bianchini, Diletta, Miranda, Susana, Carreira, Suzanne, Rescigno, Pasquale, Filipenko, Julie, Vinson, Jacob, Montgomery, Robert B., Beltran, Himisha, Heath, Elisabeth I., Scher, Howard I., Kantoff, Philip W., Taplin, Mary-Ellen, Schultz, Nikolaus, deBono, Johann S., Demichelis, Francesca, Nelson, Peter S., Rubin, Mark A., Chinnaiyan, Arul M., Sawyers, Charles L.
Publicado 2019

High-intensity sequencing reveals the sources of plasma circulating cell-free DNA variants

por Razavi, Pedram, Li, Bob T., Brown, David N., Jung, Byoungsok, Hubbell, Earl, Shen, Ronglai, Abida, Wassim, Juluru, Krishna, De Bruijn, Ino, Hou, Chenlu, Venn, Oliver, Lim, Raymond, Anand, Aseem, Maddala, Tara, Gnerre, Sante, Satya, Ravi Vijaya, Liu, Qinwen, Shen, Ling, Eattock, Nicholas, Yue, Jeanne, Blocker, Alexander W., Lee, Mark, Sehnert, Amy, Xu, Hui, Hall, Megan P., Santiago-Zayas, Angie, Novotny, William F., Isbell, James M., Rusch, Valerie W., Plitas, George, Heerdt, Alexandra S., Ladanyi, Marc, Hyman, David M., Jones, David R., Morrow, Monica, Riely, Gregory J., Scher, Howard I., Rudin, Charles M., Robson, Mark E., Diaz, Luis A., Solit, David B., Aravanis, Alexander M., Reis-Filho, Jorge S.
Publicado 2019

Clinical genomic profiling in the management of patients with soft tissue and bone sarcoma

por Gounder, Mrinal M., Agaram, Narasimhan P., Trabucco, Sally E., Robinson, Victoria, Ferraro, Richard A., Millis, Sherri Z., Krishnan, Anita, Lee, Jessica, Attia, Steven, Abida, Wassim, Drilon, Alexander, Chi, Ping, Angelo, Sandra P. D’, Dickson, Mark A., Keohan, Mary Lou, Kelly, Ciara M., Agulnik, Mark, Chawla, Sant P., Choy, Edwin, Chugh, Rashmi, Meyer, Christian F., Myer, Parvathi A., Moore, Jessica L., Okimoto, Ross A., Pollock, Raphael E., Ravi, Vinod, Singh, Arun S., Somaiah, Neeta, Wagner, Andrew J., Healey, John H., Frampton, Garrett M., Venstrom, Jeffrey M., Ross, Jeffrey S., Ladanyi, Marc, Singer, Samuel, Brennan, Murray F., Schwartz, Gary K., Lazar, Alexander J., Thomas, David M., Maki, Robert G., Tap, William D., Ali, Siraj M., Jin, Dexter X.
Publicado 2022

Immunogenomic analyses associate immunological alterations with mismatch repair defects in prostate cancer

por Nava Rodrigues, Daniel, Rescigno, Pasquale, Liu, David, Yuan, Wei, Carreira, Suzanne, Lambros, Maryou B., Seed, George, Mateo, Joaquin, Riisnaes, Ruth, Mullane, Stephanie, Margolis, Claire, Miao, Diana, Miranda, Susana, Dolling, David, Clarke, Matthew, Bertan, Claudia, Crespo, Mateus, Boysen, Gunther, Ferreira, Ana, Sharp, Adam, Figueiredo, Ines, Keliher, Daniel, Aldubayan, Saud, Burke, Kelly P., Sumanasuriya, Semini, Fontes, Mariane Sousa, Bianchini, Diletta, Zafeiriou, Zafeiris, Teixeira Mendes, Larissa Sena, Mouw, Kent, Schweizer, Michael T., Pritchard, Colin C., Salipante, Stephen, Taplin, Mary-Ellen, Beltran, Himisha, Rubin, Mark A., Cieslik, Marcin, Robinson, Dan, Heath, Elizabeth, Schultz, Nikolaus, Armenia, Joshua, Abida, Wassim, Scher, Howard, Lord, Christopher, D’Andrea, Alan, Sawyers, Charles L., Chinnaiyan, Arul M., Alimonti, Andrea, Nelson, Peter S., Drake, Charles G., Van Allen, Eliezer M., de Bono, Johann S.
Publicado 2018

Enhanced specificity of clinical high-sensitivity tumor mutation profiling in cell-free DNA via paired normal sequencing using MSK-ACCESS

por Rose Brannon, A., Jayakumaran, Gowtham, Diosdado, Monica, Patel, Juber, Razumova, Anna, Hu, Yu, Meng, Fanli, Haque, Mohammad, Sadowska, Justyna, Murphy, Brian J., Baldi, Tessara, Johnson, Ian, Ptashkin, Ryan, Hasan, Maysun, Srinivasan, Preethi, Rema, Anoop Balakrishnan, Rijo, Ivelise, Agarunov, Aaron, Won, Helen, Perera, Dilmi, Brown, David N., Samoila, Aliaksandra, Jing, Xiaohong, Gedvilaite, Erika, Yang, Julie L., Stephens, Dennis P., Dix, Jenna-Marie, DeGroat, Nicole, Nafa, Khedoudja, Syed, Aijazuddin, Li, Alan, Lebow, Emily S., Bowman, Anita S., Ferguson, Donna C., Liu, Ying, Mata, Douglas A., Sharma, Rohit, Yang, Soo-Ryum, Bale, Tejus, Benhamida, Jamal K., Chang, Jason C., Dogan, Snjezana, Hameed, Meera R., Hechtman, Jaclyn F., Moung, Christine, Ross, Dara S., Vakiani, Efsevia, Vanderbilt, Chad M., Yao, JinJuan, Razavi, Pedram, Smyth, Lillian M., Chandarlapaty, Sarat, Iyer, Gopa, Abida, Wassim, Harding, James J., Krantz, Benjamin, O’Reilly, Eileen, Yu, Helena A., Li, Bob T., Rudin, Charles M., Diaz, Luis, Solit, David B., Arcila, Maria E., Ladanyi, Marc, Loomis, Brian, Tsui, Dana, Berger, Michael F., Zehir, Ahmet, Benayed, Ryma
Publicado 2021

Mutational Landscape of Metastatic Cancer Revealed from Prospective Clinical Sequencing of 10,000 Patients

por Zehir, Ahmet, Benayed, Ryma, Shah, Ronak H., Syed, Aijazuddin, Middha, Sumit, Kim, Hyunjae R., Srinivasan, Preethi, Gao, Jianjiong, Chakravarty, Debyani, Devlin, Sean M., Hellmann, Matthew D., Barron, David A., Schram, Alison M., Hameed, Meera, Dogan, Snjezana, Ross, Dara S., Hechtman, Jaclyn F., DeLair, Deborah F., Yao, JinJuan, Mandelker, Diana L., Cheng, Donavan T., Chandramohan, Raghu, Mohanty, Abhinita S., Ptashkin, Ryan N., Jayakumaran, Gowtham, Prasad, Meera, Syed, Mustafa H., Rema, Anoop Balakrishnan, Liu, Zhen Y., Nafa, Khedoudja, Borsu, Laetitia, Sadowska, Justyna, Casanova, Jacklyn, Bacares, Ruben, Kiecka, Iwona J., Razumova, Anna, Son, Julie B., Stewart, Lisa, Baldi, Tessara, Mullaney, Kerry A., Al-Ahmadie, Hikmat, Vakiani, Efsevia, Abeshouse, Adam A., Penson, Alexander V., Jonsson, Philip, Camacho, Niedzica, Chang, Matthew T., Won, Helen H., Gross, Benjamin E., Kundra, Ritika, Heins, Zachary J., Chen, Hsiao-Wei, Phillips, Sarah, Zhang, Hongxin, Wang, Jiaojiao, Ochoa, Angelica, Wills, Jonathan, Eubank, Michael, Thomas, Stacy B., Gardos, Stuart M., Reales, Dalicia N., Galle, Jesse, Durany, Robert, Cambria, Roy, Abida, Wassim, Cercek, Andrea, Feldman, Darren R., Gounder, Mrinal M., Hakimi, A. Ari, Harding, James J., Iyer, Gopa, Janjigian, Yelena Y., Jordan, Emmet J., Kelly, Ciara M., Lowery, Maeve A., Morris, Luc G.T., Omuro, Antonio M., Raj, Nitya, Razavi, Pedram, Shoushtari, Alexander N., Shukla, Neerav, Soumerai, Tara E., Varghese, Anna M., Yaeger, Rona, Coleman, Jonathan, Bochner, Bernard, Riely, Gregory J., Saltz, Leonard B., Scher, Howard I., Sabbatini, Paul J., Robson, Mark E., Klimstra, David S., Taylor, Barry S., Baselga, Jose, Schultz, Nikolaus, Hyman, David M., Arcila, Maria E., Solit, David B., Ladanyi, Marc, Berger, Michael F.
Publicado 2017