Antiarrhythmic effect of the Ca(2+)-activated K(+) (SK) channel inhibitor ICA combined with either amiodarone or dofetilide in an isolated heart model of atrial fibrillation

por Kirchhoff, Jeppe Egedal, Diness, Jonas Goldin, Abildgaard, Lea, Sheykhzade, Majid, Grunnet, Morten, Jespersen, Thomas
Publicado 2016

The K(Ca)2 Channel Inhibitor AP30663 Selectively Increases Atrial Refractoriness, Converts Vernakalant-Resistant Atrial Fibrillation and Prevents Its Reinduction in Conscious Pigs

por Diness, Jonas Goldin, Kirchhoff, Jeppe Egedal, Speerschneider, Tobias, Abildgaard, Lea, Edvardsson, Nils, Sørensen, Ulrik S., Grunnet, Morten, Bentzen, Bo Hjorth
Publicado 2020

Inhibition of K(Ca)2 Channels Decreased the Risk of Ventricular Arrhythmia in the Guinea Pig Heart During Induced Hypokalemia

por Diness, Jonas Goldin, Abildgaard, Lea, Bomholtz, Sofia Hammami, Skarsfeldt, Mark Alexander, Edvardsson, Nils, Sørensen, Ulrik S., Grunnet, Morten, Bentzen, Bo Hjorth
Publicado 2020

Mechanisms of Action of the KCa2-Negative Modulator AP30663, a Novel Compound in Development for Treatment of Atrial Fibrillation in Man

por Bentzen, Bo Hjorth, Bomholtz, Sofia Hammami, Simó-Vicens, Rafel, Folkersen, Lasse, Abildgaard, Lea, Speerschneider, Tobias, Muthukumarasamy, Kalai Mangai, Edvardsson, Nils, Sørensen, Ulrik S., Grunnet, Morten, Diness, Jonas Goldin
Publicado 2020

The K(Ca)2 Channel Inhibitor AP14145, But Not Dofetilide or Ondansetron, Provides Functional Atrial Selectivity in Guinea Pig Hearts

por Kirchhoff, Jeppe Egedal, Skarsfeldt, Mark Alexander, Muthukumarasamy, Kalai Mangai, Simó-Vicens, Rafel, Bomholtz, Sofia Hammami, Abildgaard, Lea, Jespersen, Thomas, Sørensen, Ulrik S., Grunnet, Morten, Bentzen, Bo Hjorth, Diness, Jonas Goldin
Publicado 2019