Tumor hypoxia: an important regulator of tumor progression or a potential modulator of tumor immunogenicity?

por Hassan Venkatesh, Goutham, Abou Khouzam, Raefa, Shaaban Moustafa Elsayed, Walid, Ahmed Zeinelabdin, Nagwa, Terry, Stéphane, Chouaib, Salem
Publicado 2021

Tumor Hypoxia Regulates Immune Escape/Invasion: Influence on Angiogenesis and Potential Impact of Hypoxic Biomarkers on Cancer Therapies

por Abou Khouzam, Raefa, Brodaczewska, Klaudia, Filipiak, Aleksandra, Zeinelabdin, Nagwa Ahmed, Buart, Stephanie, Szczylik, Cezary, Kieda, Claudine, Chouaib, Salem
Publicado 2021

Dissecting the Role of AXL in Cancer Immune Escape and Resistance to Immune Checkpoint Inhibition

por Engelsen, Agnete S. T., Lotsberg, Maria L., Abou Khouzam, Raefa, Thiery, Jean-Paul, Lorens, James B., Chouaib, Salem, Terry, Stéphane
Publicado 2022

The Effect of Hypoxia and Hypoxia-Associated Pathways in the Regulation of Antitumor Response: Friends or Foes?

por Abou Khouzam, Raefa, Zaarour, Rania Faouzi, Brodaczewska, Klaudia, Azakir, Bilal, Venkatesh, Goutham Hassan, Thiery, Jerome, Terry, Stéphane, Chouaib, Salem
Publicado 2022

Hypoxia, a Targetable Culprit to Counter Pancreatic Cancer Resistance to Therapy

por Abou Khouzam, Raefa, Lehn, Jean-Marie, Mayr, Hemma, Clavien, Pierre-Alain, Wallace, Michael Bradley, Ducreux, Michel, Limani, Perparim, Chouaib, Salem
Publicado 2023

An Eight-Gene Hypoxia Signature Predicts Survival in Pancreatic Cancer and Is Associated With an Immunosuppressed Tumor Microenvironment

por Abou Khouzam, Raefa, Rao, Shyama Prasad, Venkatesh, Goutham Hassan, Zeinelabdin, Nagwa Ahmed, Buart, Stephanie, Meylan, Maxime, Nimmakayalu, Manjunath, Terry, Stéphane, Chouaib, Salem
Publicado 2021

E-cadherin Downregulation and microRNAs in Sporadic Intestinal-Type Gastric Cancer

por Rossi, Tania, Tedaldi, Gianluca, Petracci, Elisabetta, Abou Khouzam, Raefa, Ranzani, Guglielmina Nadia, Morgagni, Paolo, Saragoni, Luca, Monti, Manlio, Calistri, Daniele, Ulivi, Paola, Molinari, Chiara
Publicado 2019

Effects of nutrients on matrix metalloproteinases in human T-lymphotropic virus type 1 positive and negative malignant T-lymphocytes

por Harakeh, Steve, Abou-Khouzam, Raefa, Damanhouri, Ghazi A., Al-Hejin, Ahmed, Kumosani, Taha, Niedzwiecki, Aleksandra, Rath, Mathias, Barbour, Elie, Diab-Assaf, Mona, Azar, Rania
Publicado 2022

Chronic hypoxia is associated with transcriptomic reprogramming and increased genomic instability in cancer cells

por Abou Khouzam, Raefa, Sharda, Mohak, Rao, Shyama Prasad, Kyerewah-Kersi, Stephanie Maame, Zeinelabdin, Nagwa Ahmed, Mahmood, Ayda Shah, Nawafleh, Husam, Khan, Munazza Samar, Venkatesh, Goutham Hassan, Chouaib, Salem
Publicado 2023

Genomic Analysis of Waterpipe Smoke-Induced Lung Tumor Autophagy and Plasticity

por Zaarour, Rania Faouzi, Sharda, Mohak, Azakir, Bilal, Hassan Venkatesh, Goutham, Abou Khouzam, Raefa, Rifath, Ayesha, Nizami, Zohra Nausheen, Abdullah, Fatima, Mohammad, Fatin, Karaali, Hajar, Nawafleh, Husam, Elsayed, Yehya, Chouaib, Salem
Publicado 2022

Hypoxia increases mutational load of breast cancer cells through frameshift mutations

por Hassan Venkatesh, Goutham, Bravo, Pamela, Shaaban Moustafa Elsayed, Walid, Amirtharaj, Francis, Wojtas, Bartosz, Abou Khouzam, Raefa, Hussein Nawafleh, Husam, Mallya, Sandeep, Satyamoorthy, Kapaettu, Dessen, Philippe, Rosselli, Filippo, Thiery, Jerome, Chouaib, Salem
Publicado 2020

Multigene Panel Testing Increases the Number of Loci Associated with Gastric Cancer Predisposition

por Tedaldi, Gianluca, Pirini, Francesca, Tebaldi, Michela, Zampiga, Valentina, Cangini, Ilaria, Danesi, Rita, Arcangeli, Valentina, Ravegnani, Mila, Abou Khouzam, Raefa, Molinari, Chiara, Oliveira, Carla, Morgagni, Paolo, Saragoni, Luca, Bencivenga, Maria, Ulivi, Paola, Amadori, Dino, Martinelli, Giovanni, Falcini, Fabio, Ranzani, Guglielmina Nadia, Calistri, Daniele
Publicado 2019