Precision Breast Cancer Medicine: Early Stage Triple Negative Breast Cancer—A Review of Molecular Characterisation, Therapeutic Targets and Future Trends

por Pinilla, Karen, Drewett, Lynsey M., Lucey, Rebecca, Abraham, Jean E.
Publicado 2022

A Bayesian adaptive design for biomarker trials with linked treatments

por Wason, James M S, Abraham, Jean E, Baird, Richard D, Gournaris, Ioannis, Vallier, Anne-Laure, Brenton, James D, Earl, Helena M, Mander, Adrian P
Publicado 2015

Fbxl17 is rearranged in breast cancer and loss of its activity leads to increased global O-GlcNAcylation

por Mason, Bethany, Flach, Susanne, Teixeira, Felipe R., Manzano Garcia, Raquel, Rueda, Oscar M., Abraham, Jean E., Caldas, Carlos, Edwards, Paul A. W., Laman, Heike
Publicado 2019

Saliva samples are a viable alternative to blood samples as a source of DNA for high throughput genotyping

por Abraham, Jean E, Maranian, Mel J, Spiteri, Inmaculada, Russell, Roslin, Ingle, Susan, Luccarini, Craig, Earl, Helena M, Pharoah, Paul PD, Dunning, Alison M, Caldas, Carlos
Publicado 2012

CYP2D6 gene variants: association with breast cancer specific survival in a cohort of breast cancer patients from the United Kingdom treated with adjuvant tamoxifen

por Abraham, Jean E, Maranian, Mel J, Driver, Kristy E, Platte, Radka, Kalmyrzaev, Bolot, Baynes, Caroline, Luccarini, Craig, Shah, Mitul, Ingle, Susan, Greenberg, David, Earl, Helena M, Dunning, Alison M, Pharoah, Paul DP, Caldas, Carlos
Publicado 2010

A nested cohort study of 6,248 early breast cancer patients treated in neoadjuvant and adjuvant chemotherapy trials investigating the prognostic value of chemotherapy-related toxic...

por Abraham, Jean E., Hiller, Louise, Dorling, Leila, Vallier, Anne-Laure, Dunn, Janet, Bowden, Sarah, Ingle, Susan, Jones, Linda, Hardy, Richard, Twelves, Christopher, Poole, Christopher J., Pharoah, Paul D P, Caldas, Carlos, Earl, Helena M.
Publicado 2015

NRG1 fusions in breast cancer

por Howarth, Karen D., Mirza, Tashfina, Cooke, Susanna L., Chin, Suet-Feung, Pole, Jessica C., Turro, Ernest, Eldridge, Matthew D., Garcia, Raquel Manzano, Rueda, Oscar M., Boursnell, Chris, Abraham, Jean E., Caldas, Carlos, Edwards, Paul A. W.
Publicado 2021

The Relationship between Common Genetic Markers of Breast Cancer Risk and Chemotherapy-Induced Toxicity: A Case-Control Study

por Dorling, Leila, Kar, Siddhartha, Michailidou, Kyriaki, Hiller, Louise, Vallier, Anne-Laure, Ingle, Susan, Hardy, Richard, Bowden, Sarah J., Dunn, Janet A., Twelves, Chris, Poole, Christopher J., Caldas, Carlos, Earl, Helena M., Pharoah, Paul D. P., Abraham, Jean E.
Publicado 2016

Computational pathology of pre-treatment biopsies identifies lymphocyte density as a predictor of response to neoadjuvant chemotherapy in breast cancer

por Ali, H. Raza, Dariush, Aliakbar, Provenzano, Elena, Bardwell, Helen, Abraham, Jean E., Iddawela, Mahesh, Vallier, Anne-Laure, Hiller, Louise, Dunn, Janet. A., Bowden, Sarah J., Hickish, Tamas, McAdam, Karen, Houston, Stephen, Irwin, Mike J., Pharoah, Paul D. P., Brenton, James D., Walton, Nicholas A., Earl, Helena M., Caldas, Carlos
Publicado 2016

Multi-omic machine learning predictor of breast cancer therapy response

por Sammut, Stephen-John, Crispin-Ortuzar, Mireia, Chin, Suet-Feung, Provenzano, Elena, Bardwell, Helen A., Ma, Wenxin, Cope, Wei, Dariush, Ali, Dawson, Sarah-Jane, Abraham, Jean E., Dunn, Janet, Hiller, Louise, Thomas, Jeremy, Cameron, David A., Bartlett, John M. S., Hayward, Larry, Pharoah, Paul D., Markowetz, Florian, Rueda, Oscar M., Earl, Helena M., Caldas, Carlos
Publicado 2021

Comparison of tumor‐informed and tumor‐naïve sequencing assays for ctDNA detection in breast cancer

por Santonja, Angela, Cooper, Wendy N, Eldridge, Matthew D, Edwards, Paul A W, Morris, James A, Edwards, Abigail R, Zhao, Hui, Heider, Katrin, Couturier, Dominique‐Laurent, Vijayaraghavan, Aadhitthya, Mennea, Paulius, Ditter, Emma‐Jane, Smith, Christopher G, Boursnell, Chris, Manzano García, Raquel, Rueda, Oscar M, Beddowes, Emma, Biggs, Heather, Sammut, Stephen‐John, Rosenfeld, Nitzan, Caldas, Carlos, Abraham, Jean E, Gale, Davina
Publicado 2023

Hyperpolarized (13)C MRI of Tumor Metabolism Demonstrates Early Metabolic Response to Neoadjuvant Chemotherapy in Breast Cancer

por Woitek, Ramona, McLean, Mary A., Gill, Andrew B., Grist, James T., Provenzano, Elena, Patterson, Andrew J., Ursprung, Stephan, Torheim, Turid, Zaccagna, Fulvio, Locke, Matthew, Laurent, Marie-Christine, Hilborne, Sarah, Frary, Amy, Beer, Lucian, Rundo, Leonardo, Patterson, Ilse, Slough, Rhys, Kane, Justine, Biggs, Heather, Harrison, Emma, Lanz, Titus, Basu, Bristi, Baird, Richard, Sala, Evis, Graves, Martin J., Gilbert, Fiona J., Abraham, Jean E., Caldas, Carlos, Brindle, Kevin M., Gallagher, Ferdia A.
Publicado 2020

6 versus 12 months of adjuvant trastuzumab for HER2-positive early breast cancer (PERSEPHONE): 4-year disease-free survival results of a randomised phase 3 non-inferiority trial

por Earl, Helena M, Hiller, Louise, Vallier, Anne-Laure, Loi, Shrushma, McAdam, Karen, Hughes-Davies, Luke, Harnett, Adrian N, Ah-See, Mei-Lin, Simcock, Richard, Rea, Daniel, Raj, Sanjay, Woodings, Pamela, Harries, Mark, Howe, Donna, Raynes, Kerry, Higgins, Helen B, Wilcox, Maggie, Plummer, Chris, Mansi, Janine, Gounaris, Ioannis, Mahler–Araujo, Betania, Provenzano, Elena, Chhabra, Anita, Abraham, Jean E, Caldas, Carlos, Hall, Peter S, McCabe, Christopher, Hulme, Claire, Miles, David, Wardley, Andrew M, Cameron, David A, Dunn, Janet A
Publicado 2019

Imaging breast cancer using hyperpolarized carbon-13 MRI

por Gallagher, Ferdia A., Woitek, Ramona, McLean, Mary A., Gill, Andrew B., Manzano Garcia, Raquel, Provenzano, Elena, Riemer, Frank, Kaggie, Joshua, Chhabra, Anita, Ursprung, Stephan, Grist, James T., Daniels, Charlie J., Zaccagna, Fulvio, Laurent, Marie-Christine, Locke, Matthew, Hilborne, Sarah, Frary, Amy, Torheim, Turid, Boursnell, Chris, Schiller, Amy, Patterson, Ilse, Slough, Rhys, Carmo, Bruno, Kane, Justine, Biggs, Heather, Harrison, Emma, Deen, Surrin S., Patterson, Andrew, Lanz, Titus, Kingsbury, Zoya, Ross, Mark, Basu, Bristi, Baird, Richard, Lomas, David J., Sala, Evis, Wason, James, Rueda, Oscar M., Chin, Suet-Feung, Wilkinson, Ian B., Graves, Martin J., Abraham, Jean E., Gilbert, Fiona J., Caldas, Carlos, Brindle, Kevin M.
Publicado 2020

Hyperpolarized Carbon-13 MRI for Early Response Assessment of Neoadjuvant Chemotherapy in Breast Cancer Patients

por Woitek, Ramona, McLean, Mary A., Ursprung, Stephan, Rueda, Oscar M., Manzano Garcia, Raquel, Locke, Matthew J., Beer, Lucian, Baxter, Gabrielle, Rundo, Leonardo, Provenzano, Elena, Kaggie, Joshua, Patterson, Andrew, Frary, Amy, Field-Rayner, Johanna, Papalouka, Vasiliki, Kane, Justine, Benjamin, Arnold J.V., Gill, Andrew B., Priest, Andrew N., Lewis, David Y., Russell, Roslin, Grimmer, Ashley, White, Brian, Latimer-Bowman, Beth, Patterson, Ilse, Schiller, Amy, Carmo, Bruno, Slough, Rhys, Lanz, Titus, Wason, James, Schulte, Rolf F., Chin, Suet-Feung, Graves, Martin J., Gilbert, Fiona J., Abraham, Jean E., Caldas, Carlos, Brindle, Kevin M., Sala, Evis, Gallagher, Ferdia A.
Publicado 2021

Residual cancer burden after neoadjuvant chemotherapy and long-term survival outcomes in breast cancer: a multicentre pooled analysis of 5161 patients

por Yau, Christina, Osdoit, Marie, van der Noordaa, Marieke, Shad, Sonal, Wei, Jane, de Croze, Diane, Hamy, Anne-Sophie, Laé, Marick, Reyal, Fabien, Sonke, Gabe S, Steenbruggen, Tessa G, van Seijen, Maartje, Wesseling, Jelle, Martín, Miguel, del Monte-Millán, Maria, López-Tarruella, Sara, Boughey, Judy C, Goetz, Matthew P, Hoskin, Tanya, Gould, Rebekah, Valero, Vicente, Edge, Stephen B, Abraham, Jean E, Bartlett, John M S, Caldas, Carlos, Dunn, Janet, Earl, Helena, Hayward, Larry, Hiller, Louise, Provenzano, Elena, Sammut, Stephen-John, Thomas, Jeremy S, Cameron, David, Graham, Ashley, Hall, Peter, Mackintosh, Lorna, Fan, Fang, Godwin, Andrew K, Schwensen, Kelsey, Sharma, Priyanka, DeMichele, Angela M, Cole, Kimberly, Pusztai, Lajos, Kim, Mi-Ok, van ‘t Veer, Laura J, Esserman, Laura J, Symmans, W Fraser
Publicado 2022

Identification of Novel Genetic Markers of Breast Cancer Survival

por Guo, Qi, Schmidt, Marjanka K., Kraft, Peter, Canisius, Sander, Chen, Constance, Khan, Sofia, Tyrer, Jonathan, Bolla, Manjeet K., Wang, Qin, Dennis, Joe, Michailidou, Kyriaki, Lush, Michael, Kar, Siddhartha, Beesley, Jonathan, Dunning, Alison M., Shah, Mitul, Czene, Kamila, Darabi, Hatef, Eriksson, Mikael, Lambrechts, Diether, Weltens, Caroline, Leunen, Karin, Bojesen, Stig E., Nordestgaard, Børge G., Nielsen, Sune F., Flyger, Henrik, Chang-Claude, Jenny, Rudolph, Anja, Seibold, Petra, Flesch-Janys, Dieter, Blomqvist, Carl, Aittomäki, Kristiina, Fagerholm, Rainer, Muranen, Taru A., Couch, Fergus J., Olson, Janet E., Vachon, Celine, Andrulis, Irene L., Knight, Julia A., Glendon, Gord, Mulligan, Anna Marie, Broeks, Annegien, Hogervorst, Frans B., Haiman, Christopher A., Henderson, Brian E., Schumacher, Fredrick, Le Marchand, Loic, Hopper, John L., Tsimiklis, Helen, Apicella, Carmel, Southey, Melissa C., Cox, Angela, Cross, Simon S., Reed, Malcolm W. R., Giles, Graham G., Milne, Roger L., McLean, Catriona, Winqvist, Robert, Pylkäs, Katri, Jukkola-Vuorinen, Arja, Grip, Mervi, Hooning, Maartje J., Hollestelle, Antoinette, Martens, John W. M., van den Ouweland, Ans M. W., Marme, Federik, Schneeweiss, Andreas, Yang, Rongxi, Burwinkel, Barbara, Figueroa, Jonine, Chanock, Stephen J., Lissowska, Jolanta, Sawyer, Elinor J., Tomlinson, Ian, Kerin, Michael J., Miller, Nicola, Brenner, Hermann, Dieffenbach, Aida Karina, Arndt, Volker, Holleczek, Bernd, Mannermaa, Arto, Kataja, Vesa, Kosma, Veli-Matti, Hartikainen, Jaana M., Li, Jingmei, Brand, Judith S., Humphreys, Keith, Devilee, Peter, Tollenaar, Rob A. E. M., Seynaeve, Caroline, Radice, Paolo, Peterlongo, Paolo, Bonanni, Bernardo, Mariani, Paolo, Fasching, Peter A., Beckmann, Matthias W., Hein, Alexander, Ekici, Arif B., Chenevix-Trench, Georgia, Balleine, Rosemary, Phillips, Kelly-Anne, Benitez, Javier, Zamora, M. Pilar, Arias Perez, Jose Ignacio, Menéndez, Primitiva, Jakubowska, Anna, Lubinski, Jan, Jaworska-Bieniek, Katarzyna, Durda, Katarzyna, Hamann, Ute, Kabisch, Maria, Ulmer, Hans Ulrich, Rüdiger, Thomas, Margolin, Sara, Kristensen, Vessela, Nord, Silje, Evans, D. Gareth, Abraham, Jean E., Earl, Helena M., Hiller, Louise, Dunn, Janet A., Bowden, Sarah, Berg, Christine, Campa, Daniele, Diver, W. Ryan, Gapstur, Susan M., Gaudet, Mia M., Hankinson, Susan E., Hoover, Robert N., Hüsing, Anika, Kaaks, Rudolf, Machiela, Mitchell J., Willett, Walter, Barrdahl, Myrto, Canzian, Federico, Chin, Suet-Feung, Caldas, Carlos, Hunter, David J., Lindstrom, Sara, García-Closas, Montserrat, Hall, Per, Easton, Douglas F., Eccles, Diana M., Rahman, Nazneen, Nevanlinna, Heli, Pharoah, Paul D. P.
Publicado 2015