A microbiological system for screening the interference of XNA monomers with DNA and RNA metabolism

por Blanchard, Aude, Abramov, Mikhail, Hassan, Camille, Marlière, Philippe, Herdewijn, Piet, Pezo, Valérie
Publicado 2023

Inhibition of MDR1 expression with altritol-modified siRNAs

por Fisher, Michael, Abramov, Mikhail, Van Aerschot, Arthur, Xu, Dong, Juliano, Rudolph L., Herdewijn, Piet
Publicado 2007

Structure, stability and function of 5-chlorouracil modified A:U and G:U base pairs

por Patra, Amritraj, Harp, Joel, Pallan, Pradeep S., Zhao, Linlin, Abramov, Mikhail, Herdewijn, Piet, Egli, Martin
Publicado 2013

Highly stable hexitol based XNA aptamers targeting the vascular endothelial growth factor

por Eremeeva, Elena, Fikatas, Antonios, Margamuljana, Lia, Abramov, Mikhail, Schols, Dominique, Groaz, Elisabetta, Herdewijn, Piet
Publicado 2019

CRISPR-Cas9 recognition of enzymatically synthesized base-modified nucleic acids

por Yang, Hui, Eremeeva, Elena, Abramov, Mikhail, Jacquemyn, Maarten, Groaz, Elisabetta, Daelemans, Dirk, Herdewijn, Piet
Publicado 2023

Random-sequence genetic oligomer pools display an innate potential for ligation and recombination

por Mutschler, Hannes, Taylor, Alexander I, Porebski, Benjamin T, Lightowlers, Alice, Houlihan, Gillian, Abramov, Mikhail, Herdewijn, Piet, Holliger, Philipp
Publicado 2018

Structural Studies of HNA Substrate Specificity in Mutants of an Archaeal DNA Polymerase Obtained by Directed Evolution

por Samson, Camille, Legrand, Pierre, Tekpinar, Mustafa, Rozenski, Jef, Abramov, Mikhail, Holliger, Philipp, Pinheiro, Vitor B., Herdewijn, Piet, Delarue, Marc
Publicado 2020

Kinetic analysis of N-alkylaryl carboxamide hexitol nucleotides as substrates for evolved polymerases

por Renders, Marleen, Dumbre, Shrinivas, Abramov, Mikhail, Kestemont, Donaat, Margamuljana, Lia, Largy, Eric, Cozens, Christopher, Vandenameele, Julie, Pinheiro, Vitor B, Toye, Dominique, Frère, Jean-Marie, Herdewijn, Piet
Publicado 2019

Chimeric siRNAs with chemically modified pentofuranose and hexopyranose nucleotides: altritol-nucleotide (ANA) containing GalNAc–siRNA conjugates: in vitro and in vivo RNAi activit...

por Kumar, Pawan, Degaonkar, Rohan, Guenther, Dale C, Abramov, Mikhail, Schepers, Guy, Capobianco, Marie, Jiang, Yongfeng, Harp, Joel, Kaittanis, Charalambos, Janas, Maja M, Castoreno, Adam, Zlatev, Ivan, Schlegel, Mark K, Herdewijn, Piet, Egli, Martin, Manoharan, Muthiah
Publicado 2020

A large-scale chemical modification screen identifies design rules to generate siRNAs with high activity, high stability and low toxicity

por Bramsen, Jesper B., Laursen, Maria B., Nielsen, Anne F., Hansen, Thomas B., Bus, Claus, Langkjær, Niels, Babu, B. Ravindra, Højland, Torben, Abramov, Mikhail, Van Aerschot, Arthur, Odadzic, Dalibor, Smicius, Romualdas, Haas, Jens, Andree, Cordula, Barman, Jharna, Wenska, Malgorzata, Srivastava, Puneet, Zhou, Chuanzheng, Honcharenko, Dmytro, Hess, Simone, Müller, Elke, Bobkov, Georgii V., Mikhailov, Sergey N., Fava, Eugenio, Meyer, Thomas F., Chattopadhyaya, Jyoti, Zerial, Marino, Engels, Joachim W., Herdewijn, Piet, Wengel, Jesper, Kjems, Jørgen
Publicado 2009