The Glu102 mutation disrupts higher-order oligomerization of the sigma 1 receptor

por Abramyan, Ara M., Yano, Hideaki, Xu, Min, Liu, Leanne, Naing, Sett, Fant, Andrew D., Shi, Lei
Publicado 2020

Atomistic simulations of the Escherichia coli ribosome provide selection criteria for translationally active substrates

por Watson, Zoe L., Knudson, Isaac J., Ward, Fred R., Miller, Scott J., Cate, Jamie H. D., Schepartz, Alanna, Abramyan, Ara M.
Publicado 2023

The mechanism of a high-affinity allosteric inhibitor of the serotonin transporter

por Plenge, Per, Abramyan, Ara M., Sørensen, Gunnar, Mørk, Arne, Weikop, Pia, Gether, Ulrik, Bang-Andersen, Benny, Shi, Lei, Loland, Claus J.
Publicado 2020

The E(2.65)A mutation disrupts dynamic binding poses of SB269652 at the dopamine D2 and D3 receptors

por Verma, Ravi Kumar, Abramyan, Ara M., Michino, Mayako, Free, R. Benjamin, Sibley, David R., Javitch, Jonathan A., Lane, J. Robert, Shi, Lei
Publicado 2018

Distinct inactive conformations of the dopamine D2 and D3 receptors correspond to different extents of inverse agonism

por Lane, J Robert, Abramyan, Ara M, Adhikari, Pramisha, Keen, Alastair C, Lee, Kuo-Hao, Sanchez, Julie, Verma, Ravi Kumar, Lim, Herman D, Yano, Hideaki, Javitch, Jonathan A, Shi, Lei
Publicado 2020

The action of a negative allosteric modulator at the dopamine D(2) receptor is dependent upon sodium ions

por Draper-Joyce, Christopher J., Verma, Ravi Kumar, Michino, Mayako, Shonberg, Jeremy, Kopinathan, Anitha, Klein Herenbrink, Carmen, Scammells, Peter J., Capuano, Ben, Abramyan, Ara M., Thal, David M., Javitch, Jonathan A., Christopoulos, Arthur, Shi, Lei, Lane, J. Robert
Publicado 2018

High-potency ligands for DREADD imaging and activation in rodents and monkeys

por Bonaventura, Jordi, Eldridge, Mark A. G., Hu, Feng, Gomez, Juan L., Sanchez-Soto, Marta, Abramyan, Ara M., Lam, Sherry, Boehm, Matthew A., Ruiz, Christina, Farrell, Mitchell R., Moreno, Andrea, Galal Faress, Islam Mustafa, Andersen, Niels, Lin, John Y., Moaddel, Ruin, Morris, Patrick J., Shi, Lei, Sibley, David R., Mahler, Stephen V., Nabavi, Sadegh, Pomper, Martin G., Bonci, Antonello, Horti, Andrew G., Richmond, Barry J., Michaelides, Michael
Publicado 2019