Mechanisms Underlying Bone Loss Associated with Gut Inflammation

por Ke, Ke, Arra, Manoj, Abu-Amer, Yousef
Publicado 2019

Aseptic loosening of total joint replacements: mechanisms underlying osteolysis and potential therapies

por Abu-Amer, Yousef, Darwech, Isra, Clohisy, John C
Publicado 2007

Constitutively Active Canonical NF-κB Pathway Induces Severe Bone Loss in Mice

por Otero, Jesse E., Chen, Tim, Zhang, Kaihua, Abu-Amer, Yousef
Publicado 2012

Constitutive Activation of IKK2/NF-κB Impairs Osteogenesis and Skeletal Development

por Swarnkar, Gaurav, Zhang, Kaihua, Mbalaviele, Gabriel, Long, Fanxin, Abu-Amer, Yousef
Publicado 2014

IκB-ζ signaling promotes chondrocyte inflammatory phenotype, senescence, and erosive joint pathology

por Arra, Manoj, Swarnkar, Gaurav, Alippe, Yael, Mbalaviele, Gabriel, Abu-Amer, Yousef
Publicado 2022

Compound loss of GSDMD and GSDME function is necessary to achieve maximal therapeutic effect in colitis

por Xiao, Jianqiu, Sun, Kai, Wang, Chun, Abu-Amer, Yousef, Mbalaviele, Gabriel
Publicado 2022

Tenotomy-induced muscle atrophy is sex-specific and independent of NFκB

por Meyer, Gretchen A, Thomopoulos, Stavros, Abu-Amer, Yousef, Shen, Karen C
Publicado 2022

IKKβ Activation Is Sufficient for RANK-Independent Osteoclast Differentiation and Osteolysis

por Otero, Jesse E, Dai, Simon, Alhawagri, Muhammad A, Darwech, Isra, Abu-Amer, Yousef
Publicado 2010

Inflammatory Responses Reprogram T(REGS) Through Impairment of Neuropilin-1

por Chen, Tim Hung-Po, Arra, Manoj, Mbalaviele, Gabriel, Swarnkar, Gaurav, Abu-Amer, Yousef
Publicado 2019

Substrate Recognition by Osteoclast Precursors Induces C-src/Microtubule Association

por Abu-Amer, Yousef, Ross, F. Patrick, Schlesinger, Paul, Tondravi, M. Mehrdad, Teitelbaum, Steven L.
Publicado 1997

NUMBL Interacts with TAK1, TRAF6 and NEMO to Negatively Regulate NF-κB Signaling During Osteoclastogenesis

por Swarnkar, Gaurav, Chen, Tim Hung-Po, Arra, Manoj, Nasir, Amjad M., Mbalaviele, Gabriel, Abu-Amer, Yousef
Publicado 2017

Inflammatory osteolysis is regulated by site-specific ISGylation of the scaffold protein NEMO

por Adapala, Naga Suresh, Swarnkar, Gaurav, Arra, Manoj, Shen, Jie, Mbalaviele, Gabriel, Ke, Ke, Abu-Amer, Yousef
Publicado 2020

Myeloid Deletion of Nemo Causes Osteopetrosis in Mice Owing to Upregulation of Transcriptional Repressors

por Swarnkar, Gaurav, Shim, Kyuhwan, Nasir, Amjad M., Seehra, Kuljeet, Chen, Hung-Po (Tim), Mbalaviele, Gabriel, Abu-Amer, Yousef
Publicado 2016

Targeting angiogenesis for fracture nonunion treatment in inflammatory disease

por Wang, Cuicui, Ying, Jun, Nie, Xiaolei, Zhou, Tianhong, Xiao, Ding, Swarnkar, Gaurav, Abu-Amer, Yousef, Guan, Jianjun, Shen, Jie
Publicado 2021

Chronic inflammation triggered by the NLRP3 inflammasome in myeloid cells promotes growth plate dysplasia by mesenchymal cells

por Wang, Chun, Xu, Can-Xin, Alippe, Yael, Qu, Chao, Xiao, Jianqiu, Schipani, Ernestina, Civitelli, Roberto, Abu-Amer, Yousef, Mbalaviele, Gabriel
Publicado 2017

Bone matrix components activate the NLRP3 inflammasome and promote osteoclast differentiation

por Alippe, Yael, Wang, Chun, Ricci, Biancamaria, Xiao, Jianqiu, Qu, Chao, Zou, Wei, Novack, Deborah V., Abu-Amer, Yousef, Civitelli, Roberto, Mbalaviele, Gabriel
Publicado 2017

STING-dependent interferon signatures restrict osteoclast differentiation and bone loss in mice

por MacLauchlan, Susan, Kushwaha, Priyanka, Tai, Albert, Chen, Jia, Manning, Catherine, Swarnkar, Gaurav, Abu-Amer, Yousef, Fitzgerald, Katherine A., Sharma, Shruti, Gravallese, Ellen M.
Publicado 2023

Glutamine metabolism modulates chondrocyte inflammatory response

por Arra, Manoj, Swarnkar, Gaurav, Adapala, Naga Suresh, Naqvi, Syeda Kanwal, Cai, Lei, Farooq Rai, Muhammad, Singamaneni, Srikanth, Mbalaviele, Gabriel, Brophy, Robert, Abu-Amer, Yousef
Publicado 2022

Isoflurane Conditioning Provides Protection against Subarachnoid Hemorrhage Induced Delayed Cerebral Ischemia through NF-kB Inhibition

por Liu, Meizi, Jayaraman, Keshav, Mehla, Jogender, Diwan, Deepti, Nelson, James W., Hussein, Ahmed E., Vellimana, Ananth K., Abu-Amer, Yousef, Zipfel, Gregory J., Athiraman, Umeshkumar
Publicado 2023

Isoflurane Conditioning‐Induced Delayed Cerebral Ischemia Protection in Subarachnoid Hemorrhage—Role of Inducible Nitric Oxide Synthase

por Liu, Meizi, Jayaraman, Keshav, Norris, Aaron J., Hussein, Ahmed, Nelson, James W., Mehla, Jogender, Diwan, Deepti, Vellimana, Ananth, Abu‐Amer, Yousef, Zipfel, Gregory J., Athiraman, Umeshkumar
Publicado 2023